Clinical trials: Severe Periodontitis
Periodontal Diseases
Controlled Study Comparing REPaiR® and MIST Therapies for Treatment of Periodontitis
A comparison of laser (REPaiR) compared with minimally invasive surgical therapy for moderate to severe periodontal disease.
- Trial name
- NCT04169139
- Testing
- MIST (minimally invasive surgical therapy)
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- McGuire Institute
Periodontal Disease
Safety, Efficacy and Treatment Regimen Study of ST266 in Subjects With Moderate to Severe Periodontitis
The purpose of this study is to determine whether ST266 will reduce pocket depth (PD) as an adjunctive to scaling and root planing (SRP) in subjects with moderate to severe periodontal disease.
- Trial name
- NCT02761993
- Testing
- ST266, Saline (0.9% NaCl)
- Where
- 6 sites in United States
- Volunteers
- 151 people
- Sponsor
- Noveome Biotherapeutics, formerly Stemnion
Periodontitis Chronic Generalized Moderate, Periodontitis Chronic Generalized Severe
Regular Home-use of Dual-light Photodynamic Therapy in the Management of Chronic Stage III-IV Periodontitis
This study is designed to determine the efficacy of the Lumoral method in chronic periodontitis with a targeted group of stage III and IV periodontitis.
- Trial name
- NCT05698823
- Testing
- Lumoral Treatment
- Where
- Lithuania
- Volunteers
- 56 people
- Sponsor
- Koite Health Oy
Moderate to Severe Chronic Periodontitis
Evaluation of the KLOX BioPhotonic OraLum Gel With a LED Curing Lamp in Moderate to Severe Chronic Periodontitis
Multicenter, prospective, interventional open case series study using a randomized split-mouth design in moderate to severe chronic periodontitis patients having half-mouth treated with the KLOX BioPhotonic OraLum gel with a LED…
- Trial name
- NCT02325570
- Testing
- KLOX BioPhotonic OraLum Gel, Scaling and Root Planing (SRP)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- KLOX Technologies Inc.
Periodontitis
Efficacy and Safety of LP-005 Injection in Patients With Moderate-to-Severe Periodontitis
This is a multicenter, randomized, double-blind, placebo-controlled Phase II clinical study designed to evaluate the clinical efficacy, safety, pharmacokinetics, pharmacodynamics, and immunogenicity of multiple local injections…
- Trial name
- NCT07603713
- Testing
- LP-005 Injection
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Longbio Pharma (Suzhou) Co., Ltd.