Clinical trials: Severe Sepsis With Septic Shock
Severe Sepsis, Septic Shock
Efficacy of Melatonin in Patients With Severe Sepsis or Septic Shock
OBJECTIVES. To establish the therapeutic efficiency of melatonin in adult patients with severe sepsis and septic shock. Specifically: 1.
- Trial name
- NCT01858909
- Testing
- Melatonin
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Aragon Institute of Health Sciences
Septic Shock, Severe Sepsis
Restrictive Intravenous Fluids Trial in Sepsis
IV fluid resuscitation has long been recognized to be an important treatment for patients with severe sepsis and septic shock. While under-resuscitation is known to increase morbidity and mortality, contemporary data suggests…
- Trial name
- RIFTS (NCT03137446)
- Testing
- Intravenous Fluid Cap
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Rhode Island Hospital
Sepsis, Severe
Bispectral Index (BIS) for Classification of Procalcitonin (PCT) Sepsis Grades in Critically Ill Patients With Sepsis
To evaluate the discriminative power of BIS monitoring to classify the degree of mental state associated with the PCT graded sepsis cascade, and to assess its utility for monitoring the improvement or deterioration of sepsis.
- Trial name
- BIS6 (NCT03244293)
- Testing
- no intervention
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Suez Canal University
Shock, Septic, Severe Sepsis
Protocol-driven Hemodynamic Support for Patients With Septic Shock
This research is being done to see if a protocol (a set of orders that determine how much and how quickly a drug/fluid is given) for fluid and drugs used to increase blood pressure (vasopressors) will work better then general…
- Conditions
- Shock, Septic, Severe Sepsis, Sepsis
- Trial name
- NCT00335907
- Testing
- Fluid and Vasopressor Protocol
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- National Institute of General Medical Sciences (NIGMS)
Sepsis, Shock, Septic
Sepsis Assessment in Belgian Emergency Rooms
To validate the use of the Heparin Binding Protein (HBP) concentration to assist in the evaluation of patients admitting to the emergency department with suspected infection.
- Conditions
- Sepsis, Shock, Septic, Severe Sepsis
- Trial name
- SABER (NCT02424721)
- Where
- 4 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Axis Shield Diagnostics Ltd
Severe Sepsis, Septic Shock
Effect of Hyperglycemia in PAI-1 Activity and the Relationship With Outcome in Severe Sepsis and Septic Shock
The purpose of this study is to determine the effect of the intensive insulin therapy on coagulation and fibrinolysis in patients affected by severe sepsis and septic shock.
- Trial name
- NCT00159952
- Testing
- intensive insulin therapy
- Where
- 3 sites in Italy
- Volunteers
- 90 people
- Sponsor
- Policlinico Hospital
Septic Shock, Endotoxemia
Evaluating the Use of Polymyxin B Cartridge Hemoperfusion for Patients With Septic Shock and COVID 19
Prospective, observational, clinical investigation of PMX cartridge use in COVID 19 patients with septic shock
- Conditions
- Septic Shock, Endotoxemia, COVID, Corona Virus Infection
- Trial name
- NCT04352985
- Testing
- Toraymyxin PMX-20R (PMX Cartridge)
- Where
- 3 sites in United States
- Sponsor
- Spectral Diagnostics (US) Inc.