Clinical trials: Severe and Persistent Mental Illness
Mental Illness Persistent, Chronic Disease
Reverse Colocated Integrated Care Intervention Among Persons With Severe Persistent Mental Illness at US-Mexico Border
This study evaluated whether patients with severe and persistent mental illness (SPMI) who received coordinated co-located behavioral health and primary care services were more likely to improve health outcomes after 12 months…
- Conditions
- Mental Illness Persistent, Chronic Disease, Hypertension, Diabetes
- Trial name
- NCT03881657
- Testing
- Reverse Colocated Integrated Care, Usual Care
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Health Resources in Action, Inc.
Schizoaffective Disorder, Schizophrenia
Smoking Cessation for Veterans With Severe and Persistent Mental Illness
The investigators have developed an intervention called Behavioral Treatment of Smoking Cessation in SPMI (BTSCS), an innovative intervention that supplements pharmacotherapy and education with contingency management and a…
- Conditions
- Schizoaffective Disorder, Schizophrenia, Affective Psychosis, Bipolar, Affective Disorders, Psychotic
- Trial name
- NCT00960375
- Testing
- BTSCS, StSST
- Where
- 2 sites in United States
- Volunteers
- 179 people
- Sponsor
- US Department of Veterans Affairs
Anxiety Disorders, Generalized Anxiety Disorder
Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method
The study will compare the delivery of an 8-week Mindful Self-Compassion training, in-person against video-conference, on anxiety and depression symptom severity in patients with diagnosed anxiety disorders (generalized anxiety…
- Conditions
- Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder
- Trial name
- NCT07028216
- Testing
- Mindful Self-Compassion
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Georgetown University
Mental Illness, Schizophrenia
Cognitive Training to Enhance VA Work Program Outcomes
The purpose of this study is to determine whether augmenting work services with cognitive remediation can improve vocational outcomes for psychiatrically disabled participants in VA work services.
- Conditions
- Mental Illness, Schizophrenia, Depression, PTSD
- Trial name
- NCT00829400
- Testing
- Cognitive Remediation, Nintendo Brain Age
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- VA Connecticut Healthcare System
Schizophrenia, Schizoaffective
Safety and Tolerability of Varenicline in Schizophrenia (SATOVA)
This is a 15 week trial to determine (1) the safety and tolerability of varenicline when used for smoking cessation/reduction in individuals with schizophrenia; (2) if treatment with varenicline affects the symptoms of…
- Conditions
- Schizophrenia, Schizoaffective, Psychosis
- Trial name
- NCT00702793
- Testing
- Varenicline
- Sponsor
- University of British Columbia
Anxiety Disorders, Social Anxiety Disorder
Transdiagnostic Internet-delivered REBT Intervention for Adolescents' Internalizing Problems
To investigate the efficacy and mechanisms of change of an Internet-delivered transdiagnostic REBT intervention for adolescents with internalizing problems.
- Conditions
- Anxiety Disorders, Social Anxiety Disorder, Generalized Anxiety Disorder, Panic Disorder
- Trial name
- REBTonAd (NCT04179526)
- Testing
- Transdiagnostic Internet-delivered REBT
- Where
- Romania
- Volunteers
- 106 people
- Sponsor
- Babes-Bolyai University
Major Depressive Disorder, Persistent Depressive Disorder
Personalized Indications for CBT and Antidepressants in Treating Depression
Depression currently affects close to 2 million Canadians and is the leading cause of disability worldwide. Pharmacological treatments (antidepressant medication) and psychological treatments such as cognitive-behavioural therapy…
- Trial name
- CANBIND6 (NCT02752542)
- Testing
- Cognitive Behavioral Therapy, Pharmacotherapy
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Nova Scotia Health Authority
Disorder of Consciousness
Treating Severe Brain-injured Patients With Apomorphine
Background: Patients who survive severe brain injury may develop chronic disorders of consciousness. Treating these patients to improve recovery is extremely challenging because of scarce and inefficient therapeutical options.
- Trial name
- NCT03623828
- Testing
- Apomorphine Hydrochloride 50Mg/10mL Prefilled Syringe
- Where
- 2 sites in Belgium
- Volunteers
- 8 people
- Sponsor
- University of Liege
Brain Injury
A Study of IBRF Disorders of Consciousness Advanced Care/MultiModal Care Protocol in Severe Disorders of Consciousness
This is a study to evaluate the safety and efficacy of the IBRF ACP/MCP intervention protocol in patients with severe disorders of consciousness (SDOC).
- Trial name
- NCT02696512
- Testing
- Polypharmacy using FDA-approved products, Median Nerve Stimulation (MNS), Nutraceutical Supplementation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- International Brain Research Foundation