Clinical trials: Sevoflurane
Induction of General Anesthesia
Propofol Versus Sevoflurane for Induction of GA in Infants
This comparative study aims to investigate the haemodynamic safety profile for induction of general anesthesia in infants 3 months or less guided by electrical cardiometry parameters versus sevoflurane.
- Trial name
- NCT05105022
- Testing
- Propofol
- Where
- Egypt
- Volunteers
- 122 people
- Sponsor
- Cairo University
Postoperative Recovery, Inhalation Anesthesia
Effect of Combined Intravenous-Inhalational Anesthesia (CIVIA) on Postoperative Recovery Patterns.
This study was planned as a single-center, prospective, randomized trial. Adult patients undergoing elective spinal surgery lasting longer than three hours, performed in a neurosurgery operating room, will be evaluated.
- Conditions
- Postoperative Recovery, Inhalation Anesthesia, Total Intravenous Anesthesia
- Trial name
- NCT07123870
- Testing
- Sevofluorane, Desflurane, Total Intravenous Anesthesia(TIVA)
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Aged, Neoplasms
Impact of Anesthesia Maintenance Methods on 5-year Survival After Surgery
Surgery is one of the major treatment methods for patients with solid organ cancer. And, alone with the ageing process, more and more elderly patients undergo surgery for cancer.
- Conditions
- Aged, Neoplasms, Surgical Procedure, Operative, Anesthesia, Inhalation
- Trial name
- NCT05343260
- Testing
- Sevoflurane, Propofol
- Where
- 15 sites in China
- Volunteers
- 1,228 people
- Sponsor
- Peking University First Hospital
Throid Surgery, Airway Complication of Anaesthesia
Comparison of the Effects of Total Intravenous Anaesthesia With Target-Controlled Infusion (TCI) and Inhalation Anaesthesia on Airway Complications During Extubation and in the Early Postoperative Period in Thyroidectomy Surgery
Thyroid surgery is one of the most complex operations in the head and neck region due to its close relationship with anatomical structures and the high risk of recurrent laryngeal nerve injury.
- Conditions
- Throid Surgery, Airway Complication of Anaesthesia, Coughing Responses at Tracheal Extubation, Laryngospasm on Emergence
- Trial name
- NCT07325669
- Testing
- tıva
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- dilara gocmen
Intraocular Pressure, Anesthesia
Intraocular Pressure in Patients Undergoing Coronary Artery Bypass Graft Surgery With Cardiopulmonary Bypass
The aim of the study to compare the effects of sevoflurane-based anesthesia and propofol-based total intravenous anesthesia on intraocular pressure (IOP) during coronary artery bypass graft surgery (CABG) with cardiopulmonary…
- Trial name
- NCT06494969
- Testing
- Intraocular pressure measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Antalya Training and Research Hospital
Cardiac On-pump Surgery
Organ Protection With Sevoflurane Postconditioning After Cardiac Surgery With Cardiopulmonary Bypass
Organ protection, volatile anesthetics, postconditioning. Sedation of patients on ICU after cardiac surgery with cardiopulmonary bypass with either propofol or sevoflurane.
- Trial name
- NCT00924222
- Testing
- Sevoflurane, Propofol
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- University of Zurich
Anesthesia
Comparative Population Pharmacodynamic Modeling for Sevoflurane Effects Using ADMS and Bispectral Index
The investigators want to compare the performance of anesthetic depth monitoring for sedation (ADMS) to the bispectral index (BIS) as electroencephalographic measures of sevoflurane effect using two combined sigmoidal Emax models…
- Trial name
- NCT03069456
- Testing
- BIS, ADMS
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chonnam National University Hospital
Analgesia
Confirmatory Study of HFVI Guided Analgesic Administration in Surgical Subjects
The current study is intended to be a prospective clinical performance validation study designed to confirm the clinical utility of HFVI-guided fentanyl administration during sevoflurane anesthesia.
- Trial name
- NCT04049656
- Testing
- HFVI
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Florida
Postoperative Delirium
Researching the Affect of Sevoflurane in Cardiac Surgery on Delirium
Many risk factors have been identified for delirium after open heart surgery . One of the main risk factors; duration of stay on mechanical ventilator .
- Trial name
- NCT05365165
- Testing
- Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Derince Training and Research Hospital
Postoperative Pain
Propofol Versus Sevoflurane on Acute Postoperative Pain
This study was performed to compare the acute postoperative pain intensity and opioid consumption after total shoulder arthroplasty between propofol-remifentanil and sevoflurane-remifentanil anesthesia.
- Trial name
- NCT04333992
- Testing
- propofol and remifentanil, sevoflurane and remifentanil
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Yeungnam University College of Medicine
Delirium
The Effect of Remifentanil Infusion During Emergence on the Incidence of Emergence Delirium
The aim of the present study is to assess the effect of postoperative remifentanil infusion on the incidence of emergence agitation in preschool-aged children undergoing strabismus surgery with sevoflurane anaesthesia.
- Trial name
- NCT02108795
- Testing
- Remifentanil
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Yeungnam University College of Medicine
Brain Ischemia
The Neuroprotection of Sevoflurane Preconditioning on Intracranial Aneurysm Surgery
The current study is designed to clarify the neuroprotective effect of sevoflurane preconditioning on the patients underwent intracranial aneurysm surgery.
- Trial name
- NCT01204268
- Testing
- Sev-I group, Sevo continuous inhalation
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xijing Hospital
Anesthesia, Neurotoxicity
A Study to Compare the Long-term Outcomes After Two Different Anaesthetics
There is considerable evidence that most general anaesthetics modulate brain development in animal studies. The impact is greater with longer durations of exposure and in younger animals.
- Conditions
- Anesthesia, Neurotoxicity, Child Development
- Trial name
- TREX (NCT03089905)
- Testing
- Sevoflurane, Remifentanil, Dexmedetomidine
- Where
- 21 sites in United States, Australia and 2 more
- Volunteers
- 450 people
- Sponsor
- Murdoch Childrens Research Institute
Sevoflurane Desflurane, Metabolomic Effect
Comparison of the Metabolomic Effects of Sevoflurane and Desflurane Anesthesia in Laparoscopic Cholecystectomy
Analytical techniques used in metabolomic studies include nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS).
- Trial name
- NCT07399223
- Testing
- Sevoflurane, Desflurane
- Volunteers
- 80 people
- Sponsor
- Harran University
Emergence Delirium
The PREVENT AGITATION Trial II - Children ≤1 Year
Emergence agitation is a clinical condition in which the child experiences a variety of behavioural disturbances including crying, thrashing, and disorientation during early awakening from anaesthesia.
- Trial name
- NCT05091242
- Testing
- Clonidine, Sodium chloride
- Where
- 2 sites in Australia, Denmark
- Volunteers
- 336 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Metabolic Acidosis
Effect of Propofol and Sevoflurane on Lactate During Anesthesia for Pediatric Heart Catheterisation
Propofol is routinely used for general anesthesia during pediatric heart catheterisation. Propofol infusion syndrome (PRIS) is a rare, but often fatal complication mainly defined by bradycardia with progress to asystolia during…
- Trial name
- PRISCATHLAB (NCT01293266)
- Testing
- Propofol
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University Hospital Schleswig-Holstein
Kidney Transplant
Effects Of Propofol And Sevoflurane On Plasma Mirna Levels İn Living Kidney Donors
Surgical interventions and associated tissue trauma induce a complex systemic inflammatory stress response characterized by the activation of neuroendocrine, metabolic, and immunological systems.
- Trial name
- NCT07760402
- Testing
- Sevoflurane, propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Pulmonary Aspiration
To Compare Effect of Sevoflurane Versus Desflurane on the Return of Swallowing Reflexes in the Elderly
Anaesthesia and surgery has become more common in the elderly as the population survives longer. Anaesthesia in the elderly confers a higher risk which is related to the aging process and the diseases that accompany seniority.
- Trial name
- NCT01833676
- Testing
- Sevoflurane, Desflurane
- Where
- Malaysia
- Volunteers
- 51 people
- Sponsor
- University of Malaya
Aortic Diseases, Abdominal
Opioid-potentiated Volative Anaesthetic Vs. Remifentanil And Propofol During Abdominal Aortic Aneurysm Surgery
Comparing 2 different anaesthetic methods during abdominal aortic aneurysm surgery. The patients will be followed up 30 days postoperative. Number of patients included will be 200. Perioperative details will be analyzed.
- Conditions
- Aortic Diseases, Abdominal, Aneurysm, Surgery
- Trial name
- ABSENT (NCT00538421)
- Testing
- Propofol, Sevoflurane
- Where
- Norway
- Volunteers
- 193 people
- Sponsor
- Sykehuset i Vestfold HF
Emergence Delirium
Emergence Delirium in Children: Total Intravenous Anesthesia With Propofol and Remifentanil Versus Inhalational Sevoflurane Anesthesia
Emergence delirium (ED) refers to a wide variety of behavioural disturbances that are commonly seen in children following emergence from anesthesia.
- Trial name
- NCT00885443
- Testing
- Propofol, sevoflurane
- Where
- Canada
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of British Columbia