Clinical trials: Sevoflurane Anesthesia
Ear Deformities, Acquired
The Effect of General Anesthesia on the Middle Ear Pressure
The investigators aimed to examine the effect of sevoflurane and desflurane, agents used in patients who do not have any ear pathology and undergo surgery under general anesthesia, on the MEP.
- Trial name
- NCT03100604
- Testing
- desflurane,, Sevoflurane
- Volunteers
- 50 people
- Sponsor
- Trakya University
Pituitary Adenoma
Comparison of The Effects of Sevoflurane, Desflurane and Total Intravenous Anaesthesia on Pulmonary Function Tests
This study will compare the effects of sevoflurane, desflurane and total intravenous anaesthesia on pulmonary function tests in patients undergoing endoscopic endonasal transsphenoidal surgery of pituitary gland.
- Trial name
- NCT02709863
- Testing
- Sevoflurane, Desflurane, Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Anesthesia
Difference of Plasma Orexin A Levels Between Elderly and Young Patients at Emergence
The current study is designed to investigate the difference of plasma orexin A levels between elderly and young patients at emergence from sevoflurane-fentanyl anesthesia who will undergo elective lumbar surgery.
- Trial name
- NCT01478906
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xijing Hospital
Ovarian Cancer
Influences of Propofol and Sevoflurane Anesthesia in Ovarian Cancer (Anesthetics)
Ⅶ. Study procedures (summary) 1. Written informed consent must be obtained before any study specific procedures are undertaken. Qualified participants were identified at the pre-anesthesia evaluation clinic or ward.
- Trial name
- anesthetics (NCT05606692)
- Testing
- Propofol 1%, Sevoflurane/Ultane
- Where
- Taiwan
- Volunteers
- 416 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Renal Failure, Anesthesia
Renal Function During Pediatric Anesthesia
It is known that volatile anesthesia, such as sevoflurane, retain water and that this appears more pronounced in children. However, the mechanisms for this effect is unknown and it is not clear if the commonly used anesthetic…
- Trial name
- NCT02571426
- Testing
- Sevoflurane, propofol
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Sevoflurane Anesthesia
The Effect of Sevoflurane on Cerebral CO2 Sensitivity and Systemic Arteries
Purpose: The purpose of this study is to examine the effect of different carbon-dioxide concentrations on cerebral CO2 sensitivity and the resistance and stiffness of systemic arteries during anesthesia with sevoflurane.
- Trial name
- NCT02054143
- Testing
- Partial pressure of CO2 at the end of an exhaled breath, Sevoflurane
- Where
- Hungary
- Volunteers
- 24 people
- Sponsor
- University of Debrecen
Postoperative Cognitive Dysfunction, Delirium
Cohort Study to Investigate the Association Between Changes in Brain Volume and Postoperative Cognitive Dysfunction
Despite an ongoing controversy in the scientific literature, the link between anesthesia and dementia and/or cerebral atrophy remains unclear.
- Conditions
- Postoperative Cognitive Dysfunction, Delirium, Dementia
- Trial name
- POCD-MRI (NCT02045004)
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nicolai Goettel
Child, Only, Inhalation; Vapor
Cerebral and Peripheral Near Infrared Spectroscopy Monitoring in Low and High Flow Anaesthesia in Pediatric
To investigate the effects of non-invasive cerebral and peripheral NIRS monitoring and low and high flow sevoflurane anaesthesia on cerebral and peripheral NIRS in paediatric patients.
- Conditions
- Child, Only, Inhalation; Vapor, Anesthesia, Cerebral Oxygenation
- Trial name
- NCT06320743
- Testing
- NIRS ,Ventilation parameters, Oxygen concentration
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ankara City Hospital Bilkent
General Anesthesia, Geriatric Patient
Sevoflurane and Propofol Anesthesia on Postoperative Delirium
Delirium is defined as an acute onset and fluctuating course of mental status change with inattention and an altered level of consciousness.
- Trial name
- NCT01995214
- Testing
- Propofol, Sevoflurane
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Huazhong University of Science and Technology
Delirium, Postoperative Complications
Impact of Anesthesia Maintenance Methods on Incidence of Postoperative Delirium
Surgery is one of the major treatment methods for patients with malignant tumor. And, alone with ageing process, more and more elderly patients undergo surgery for malignant tumor.
- Conditions
- Delirium, Postoperative Complications, Postoperative Cognitive Dysfunction
- Trial name
- NCT02662257
- Testing
- Sevoflurane, Propofol
- Where
- 17 sites in China
- Volunteers
- 1,228 people
- Sponsor
- Peking University First Hospital
Anesthesia, Tolerance
Tolerance to Sevoflurane in Children Undergoing Repeated Drug Exposure
Deep sedation or general anesthesia is frequently required for infant that need radiotherapy to treat malignancies. As radiation therapy usually consist of several sessions, these patients are exposure to several consecutive…
- Trial name
- NCT04188782
- Testing
- Sevoflurane
- Where
- 2 sites in Chile
- Volunteers
- 24 people
- Sponsor
- University of Chile
Chalazion
Effect of Different Concentrations of Sevoflurane for Anesthesia Induction in Pediatric Ophthalmic Surgery
This randomized controlled trial aims to compare the effectiveness and safety of 6% versus 8% sevoflurane inhalation induction in pediatric patients undergoing minor ophthalmic surgery.
- Trial name
- SEVO-PED (NCT07450495)
- Testing
- Sevoflurane
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong
Anesthesia
Anesthesia and Lymphocytes Apoptosis
Most researches revealed that volatile anesthetic sevoflurane has a more marked cardioprotective effect against ischemia compared with intravenous agent propofol.However, propofol has been suggested to be more benefit for…
- Trial name
- OPCAB (NCT01461551)
- Testing
- Sevoflurane, Propofol, combine of sevoflurane and propofol
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Ruijin Hospital
Vocal Cord; Injury, Superficial
Laryngeal Injuries After Removal of the Tracheal Tube: A Comparison Between Sevoflurane and Propofol
Vocal cord injuries occur not only during tracheal intubation, but also during surgery and during removal of tracheal tube. Volatile anesthetics increase neuromuscular block of muscle relaxants.
- Trial name
- NCT01616966
- Testing
- Sevoflurane, propofol
- Where
- Germany
- Volunteers
- 65 people
- Sponsor
- University of Rostock
Inhalation; Gas
Sevoflurane Wash in Method Using Conventional Flows Versus Low Flows of 0.5L
The goal of this observational study is to to evaluate a technique of initiating Sevoflurane low-flow anesthesia which is simple, has a quick wash-in and minimises gas consumption without compromising the safety when compared to…
- Trial name
- NCT06209112
- Testing
- Sevoflurane
- Where
- Oman
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Royal Hospital, Oman
Anesthesia,General, Cardiac Event
Hemodynamic Parameters and Cardiac Enzyme Levels in Patients Undergoing General Anesthesia
The goal of this observational study is to learn about the effects of total intravenous general anesthesia with target controlled infusion and sevoflurane based balanced general anesthesia on hemodynamic parameters and cardiac…
- Trial name
- NCT05598567
- Testing
- target controlled infusion - total intravenous general anesthesia, sevoflurane based balanced general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Duzce University
Anesthesia, Cardiac Surgery
Sevoflurane in Cardiac Surgery
Patients undergoing high risk cardiac surgery (combined CABG and valvular procedures) will be randomized to receive a total intravenous anesthesia or an anesthesia plan with sevoflurane.
- Trial name
- SEVO AIFA (NCT00821262)
- Testing
- sevoflurane, propofol
- Where
- 5 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Università Vita-Salute San Raffaele
Paediatrics, General Anaesthesia
Comparison of the Anaesthetic Gases in Maintainance of General Anaesthesia in Paediatrics
Desflurane and Sevoflurane are one of the modern inhalational anaesthetic agents currently in use in anaesthetic practice. The properties of desflurane that has low blood gas solubility coefficient of 0.47 compared to sevoflurane…
- Trial name
- NCT04771962
- Testing
- DESFLURANE AND SEVOFLURANE
- Where
- Malaysia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Varicose Vein, Postoperative Pain
Propofol Versus Volatile Anesthesia in Post Operative Pain Management
The study will test the hypothesis that patients anesthetized with propofol suffer less postoperative pain than those anesthetized with sevoflurane.
- Trial name
- NCT00712517
- Testing
- propofol, sevoflurane
- Where
- Austria
- Volunteers
- 90 people
- Sponsor
- The Cleveland Clinic
General Anesthesia, Sevoflurane
Efficacy and Safety of Sevofran in Patients Scheduled for Elective Surgery Under General Anesthesia
Sevoflurane is currently being used in more than 100 countries worldwide with an estimated 100 million operations having been performed using sevoflurane as a general anesthetic.
- Conditions
- General Anesthesia, Sevoflurane, Generic Drugs
- Trial name
- NCT01096212
- Testing
- original sevoflurane, generic sevoflurane
- Where
- 2 sites in South Korea
- Volunteers
- 178 people
- Sponsor
- Asan Medical Center