Clinical trials: Sevoflurane Anesthesia
Anesthetic Gas Consumption and Cost-Effectiveness
Comparison of Different Ventilator and Vaporizer Technologies to Study Economic and Environmental Implications
The purpose of this study is to test whether or not the use of a low volume ventilator in an anesthesia machine reduces anesthetic costs significantly as compared to other high volume machines.
- Trial name
- NCT04851314
- Testing
- ICU certified ventilator, Non-ICU certified ventilator
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of California, Irvine
Catheter Site Discomfort, Complications
Propofol and Sevoflurane for Catheter-Related Bladder Discomfort
The investigators want to evaluate the efficacy of the propofol and sevoflurane for the prevention of catheter-related bladder discomfort.
- Conditions
- Catheter Site Discomfort, Complications, Anesthesia, Urinary Bladder Neoplasms
- Trial name
- NCT02252445
- Testing
- Propofol, Sevoflurane
- Where
- South Korea
- Volunteers
- 82 people
- Sponsor
- Seoul National University Hospital
Surgical Conditions
Effect of Deep Versus Moderate Neuromuscular Block During Sevoflurane Anesthesia on Intraoperative Surgical Conditions.
A deep neuromuscular block (NMB) is often associated with improved surgical conditions especially in laparoscopic surgery. We previously showed that deep NMB is superior to a moderate NMB under propofol anesthesia.
- Trial name
- BLISS4 (NCT03170661)
- Testing
- Deep neuromuscular block
- Where
- Netherlands
- Volunteers
- 98 people
- Sponsor
- Leiden University Medical Center
Emergence Agitation, Pain
Emergence Agitation and Pain Scores in Pediatrics When Comparing Single-modal vs Multi-modal Analgesia for ENT Surgery
The purpose of this study is to compare the incidence of EA in pediatric patients undergoing minor ENT surgery under Sevoflurane and compare opioid-only based intra-operative analgesia to multi-modal analgesia consisting of…
- Trial name
- NCT03062488
- Testing
- IV acetaminophen, Fentanyl, PO acetaminophen
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Deep Sedation, Anesthesia, General
Addition of Nitrous Oxide and Its Effects on Depth of Anesthesia
The study hypothesizes that adding 60% nitrous oxide to a steady state sevoflurance or propofol anesthetic will lead to a decrease in both BIS and Entropy indices during a constant level of surgical stimulus
- Trial name
- N20 (NCT00717574)
- Testing
- Sevoflurane group, Propofol group
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Oklahoma
Cystoscopes, Baxter Anaesthesia Brand of Desflurane
Comparing Desflurane to Sevoflurane for the Effect on Recovery Time in Patients Undergoing Urological Cystoscope Surgery
This is a single-center, prospective, randomized, double-blind, double-arm trial including 68 subjects scheduled to undergo urological cystoscope surgeries under general anesthesia (GA) with intubation through a laryngeal mask…
- Conditions
- Cystoscopes, Baxter Anaesthesia Brand of Desflurane, Sevoflurane
- Trial name
- NCT01219881
- Testing
- Desflurane, Sevoflurane
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Surgery, Anesthesia
Propofol Versus Sevoflurane Recovery After Gynecological Surgery
80% of 25 million American who undergo surgery describe moderate to severe pain. The use of multimodal analgesic techniques can attenuate patient's postoperative pain and several different medication have been found to be…
- Trial name
- NCT01755234
- Testing
- Sevoflurane, Propofol
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Northwestern University
Anesthesia
Anesthesia and Lymphocytes Apoptosis
Most researches revealed that volatile anesthetic sevoflurane has a more marked cardioprotective effect against ischemia compared with intravenous agent propofol.However, propofol has been suggested to be more benefit for…
- Trial name
- OPCAB (NCT01461551)
- Testing
- Sevoflurane, Propofol, combine of sevoflurane and propofol
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Ruijin Hospital
Coronary Artery Disease, General Anesthetic Drug Allergy
Xenon Compared to Sevoflurane and Total Intravenous Anaesthesia for Coronary Artery Bypass Graft Surgery
Xenon is a gaseous anaesthetic agent registered in several European countries. It has been administered safely during cardiac surgery in pilot studies.
- Conditions
- Coronary Artery Disease, General Anesthetic Drug Allergy, Coronary Artery Bypass Graft Surgery
- Trial name
- NCT01294163
- Testing
- Xenon, Sevoflurane, Propofol
- Where
- 17 sites in France, Germany and 2 more
- Volunteers
- 509 people
- Sponsor
- Air Liquide Santé International
Chronic Rhinosinusitis
Total Intravenous Anesthesia (TIVA) vs. Inhaled Anesthesia for Endoscopic Sinus Surgery.
The purpose of this study is to compare total intravenous anesthesia to inhaled anesthesia in endoscopic sinus surgery for chronic sinusitis.
- Trial name
- NCT01214057
- Testing
- Propofol and Remifentanyl, Sevoflurane and Remifentanyl
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- The University of Texas Health Science Center, Houston
Anesthesia
Bispectral Index and End-Tidal Anesthetic Gas Concentration in Pediatric Patients
The purpose of this study is to investigate the relationship between BIS™ values including EEG profile and anesthetic agents in the pediatric population
- Trial name
- BTIGER (NCT04810481)
- Testing
- BIS Complete Monitoring System
- Where
- 8 sites in United States
- Volunteers
- 209 people
- Sponsor
- Medtronic - MITG
Emergence Agitation, Pain
Can Acetaminophen Given 1-2 Hours to Children Before Ear Tube Surgery Reduce Agitation After Anesthesia?
Emergence agitation (EA) occurs in up to 67% of pediatric patients after anesthesia for bilateral myringotomy tubes (BMT, "ear tubes").
- Trial name
- NCT01737593
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Airway Complication of Anaesthesia, Healthy
The Effects of General Anesthetics on Upper Airway Collapsibility in Healthy Subjects
The investigators hypothesize that propofol, when compared to sevoflurane, causes the upper airway to collapse more easily and causes less activity in the tongue muscle.
- Trial name
- NCT01557920
- Testing
- Propofol, Sevoflurane
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Anesthesia, General
Using the SEDLine for the Titration of Sevoflurane in Elderly Patients Recovery Using the SEDLine TM for the Titration of Sevoflurane in Elderly Patients Undergoing Non-Cardiac Surgery After Beta-Adrenergic Blockade
Asses the effect of the use of Patient State Index (PSI) monitoring on difference in emergence profiles in the elderly (age >65 yrs) population to develop a cost-benefit profile.
- Trial name
- NCT00938782
- Testing
- Sedline
- Where
- 2 sites in United States
- Volunteers
- 67 people
- Sponsor
- Stanford University
Acute Pain
ANI Versus Standard Care in Surgical Patients Receiving Balanced Sevoflurane-Fentanyl Anesthesia
This study aims to be a randomized, controlled study of ANI-guided opioid administration versus standard clinical practice in surgical patients undergoing general anesthesia with balanced sevoflurane-fentanyl.
- Trial name
- NCT03684590
- Testing
- ANI-guided opioid administration, Standard opioid administration
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Blood Loss
Intraoperative Bleeding During Endoscopic Sinus Surgery
The purpose of this study is to compare the blood loss during sinus surgery looking at two different types of anesthesia: either intravenous anesthesia with propofol or inhalational anesthesia with sevoflurane.
- Trial name
- NCT01014728
- Testing
- propofol, sevoflurane
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Anesthesia, General
Estimate the Behavior of Chinese Anesthesiologists Practicing General Anesthesia With Sevoflurane
This registry is primarily aiming to demonstrate the correlation between good practices of anesthesiologists and patient related outcomes including decreased overall anesthesia cost.
- Trial name
- NCT01199471
- Where
- 40 sites in China
- Volunteers
- 4,000 people
- Sponsor
- Abbott
Liver Dysfunction
Markers of Liver Apoptosis After Anesthesia With Sevoflurane or Propofol
Anesthesia may affect the function of vital organs. Liver is one of them. The investigator's hypothesis is that intravenous or inhalation anesthesia does not impair liver function as assessed by more elegant tests like markers…
- Trial name
- NCT01000337
- Testing
- Sevoflurane, Propofol
- Where
- Greece
- Volunteers
- 67 people
- Sponsor
- University of Athens
Anaesthesia
Study of Anaesthesia Costs and Recovery Profiles
The purpose of this study is to compare the perioperative hemodynamic parameters, recovery profiles and cost containment of sevoflurane and propofol based general anesthesia for otorhinolaryngeal surgery.
- Trial name
- SACRP (NCT02920749)
- Testing
- Sevoflurane group A, Sevoflurane group B, Propofol group C
- Where
- Hungary
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Emergence Delirium
Emergence Agitation Between Dexmedetomidine and Sevoflurane Anesthesia
Emergence agitation is commonly encountered after receiving inhalation anesthesia. This distressing phenomenon carries risks that are harmful to patients, caregivers and medical personnel.
- Trial name
- NCT06482125
- Testing
- Dexmedetomidine, Sevoflurane
- Where
- Indonesia
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Pelita Harapan University