Clinical trials: Sexual Arousal Disorder
Hypoactive Sexual Desire Disorder (DSM-IV-TR Defined), Sexual Interest/Arousal Disorder (DSM-5 Defined)
Phase 1b/2a Unblinded Study of Responses in Premenopausal Women With HSDD to Lorexys Evaluating Efficacy and Safety
The purpose of this study is to investigate whether Lorexys is effective and safe to treat premenopausal women who have lost their sexual desire to a distressing degree.
- Trial name
- PURPLE (NCT01857596)
- Testing
- bupropion, Lorexys low-dose, Lorexys moderate-dose
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- S1 Biopharma, Inc.
Female Sexual Arousal Disorder, Hypoactive Sexual Desire Disorder
Bremelanotide in Premenopausal Women With Female Sexual Arousal Disorder and/or Hypoactive Sexual Desire Disorder
This trial is designed to evaluate the efficacy and safety of 3 fixed dose levels of bremelanotide, administered subcutaneously on an as-needed basis under conditions of home use, for the treatment of female sexual arousal…
- Trial name
- NCT01382719
- Testing
- bremelanotide
- Where
- 68 sites in United States, Canada
- Volunteers
- 612 people
- Sponsor
- Palatin Technologies, Inc
Sexual Dysfunction, Physiological
The Efficacy, Safety And Toleration Of CP-866,087 In Pre-Menopausal Women With Female Sexual Arousal Disorder.
CP-866,087 is a non-hormonal compound, acting on the central nervous system, which has been shown in animal models to restore sexual function.
- Trial name
- NCT00482664
- Testing
- CP-866,087
- Where
- 12 sites in Australia, Denmark and 3 more
- Volunteers
- 84 people
- Sponsor
- Pfizer
IBS - Irritable Bowel Syndrome
Sex Differences in Effectiveness of CBT on IBS Project 3
Cognitive Behavioral Therapy (CBT) is the most well researched and most effective treatment for IBS targeting the brain-gut-microbiome (BGM) axis, and preliminary data show that this therapeutic effect is associated with a…
- Trial name
- U54_P3_CBT (NCT05155631)
- Testing
- COGNITIVE BEHAVIORAL THERAPY
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- University of California, Los Angeles
Sexual Dysfunctions, Psychological
Study of Pharmacological Treatment in Women With Female Sexual Interest/Arousal Disorder (FSIAD).
This clinical trial is a prospective, randomized, double-blind Phase III study with two arms to determine the efficacy and safety of the use of an IPDE in women with FSIAD.
- Trial name
- FSIAD (NCT04433559)
- Testing
- Tadalafil 1,5 mg oral tablets
- Volunteers
- 80 people
- Sponsor
- Lidia Larrañaga
Sexual Dysfunctions, Psychological, Sexual Arousal Disorder
An Open-Label, Extension Study Evaluating the Safety, Toleration, and Efficacy of Sildenafil in Women With Sexual Arousal Disorder
The purpose of this study is to evaluate the safety and toleration of oral sildenafil administered as required by women with Female Sexual Arousal Disorder (FSAD) who successfully complete one of the following Pfizer-sponsored…
- Trial name
- NCT00746967
- Testing
- sildenafil
- Where
- 82 sites in United States
- Volunteers
- 267 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Sexual Dysfunctions, Psychological
Group Psychoeducational Treatment for Women With Sexual Arousal Difficulties
The purpose of this study is to pilot test and determine the feasibility of a psychoeducational intervention (PED) we recently developed in a group format for women with acquired sexual arousal disorder (FSAD).
- Trial name
- NCT00175539
- Testing
- psychoeducational intervention
- Where
- 2 sites in Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Paraphilias and Paraphilic Disorders
Enhancing Consensual Social Skills to Prevent Non-consensual Sexual Acts
A challenge to Canadian society is the establishment of effective evidence-based interventions to prevent non-consensual sex acts.
- Trial name
- NCT05830643
- Testing
- Social skills group psychotherapy, Adult interest group psychotherapy
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- The Royal Ottawa Mental Health Centre
Hypoactive Sexual Desire Disorder, Vulvovaginal Disease
Effect of Testosterone Treatment on Clitoral Arteries' Hemodynamic Parameters.
The regulation of clitoral vascularization by sex steroids is still under-investigated. We aimed to explore the effects of 6 months transdermal Testosterone (T) therapy on clitoral color Doppler ultrasound (CDU) parameters in…
- Conditions
- Hypoactive Sexual Desire Disorder, Vulvovaginal Disease, Menopause Related Conditions, Dyspareunia (Female Excluding Psychogenic)
- Trial name
- TESTOFSD (NCT04336891)
- Testing
- Testosterone gel, Estradiol ovules, Moisturizer
- Where
- Italy
- Volunteers
- 81 people
- Sponsor
- University of Florence
Female Sexual Arousal Disorder
Heart Rate Variability Biofeedback for Female Sexual Arousal Disorder
Low resting heart rate variability (HRV) has been associated with sexual arousal problems and overall sexual dysfunction in women.
- Trial name
- NCT02958176
- Testing
- HRV Biofeedback, Autogenic Training
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Texas at Austin
Female Sexual Dysfunction
Surface Stimulation for Female Sexual Dysfunction
Female sexual dysfunction, including sexual arousal disorder, has a significant clinical impact, affecting millions of women in the United States alone.
- Trial name
- NCT02692417
- Testing
- Transcutaneous Electrical Nerve Stimulation
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Timothy Bruns
Female Sexual Arousal Disorder
Examining Caffeine as a Treatment for Antidepressant-induced Arousal Dysfunction in Women
Antidepressants have negative effects on genital arousal function that hinder quality of life and jeopardize medication adherence.
- Trial name
- NCT05685407
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas at Austin
Female Sexual Dysfunction
the Ameliorating Effects of Antioxidant Gel on Female Arousal Disorder and Sexual Dysfunction
The aim of this study is to evaluate the quality of sexual life of females with sexual interest or arousal disorder before and after accurate application of a formulated emulgel made from natural ingredients, including kaempferol…
- Trial name
- NCT06060691
- Testing
- Kaempferol
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Deraya University
Vulvovaginal Signs and Symptoms, Genitourinary Syndrome of Menopause
Effects of Ospemifene on Brain Activation Patterns in Women With Sexual Interest-arousal Disorders
Ospemifene is the first oral and non-hormonal treatment for moderate or severe vulvo-vaginal atrophy (VVA) in postmenopausal women who are not candidates to treatment with local oestrogens.
- Conditions
- Vulvovaginal Signs and Symptoms, Genitourinary Syndrome of Menopause, Sexual; Disorder, Arousal, Female
- Trial name
- EROS (NCT04677491)
- Testing
- Ospemifene 60 mg, fMRI experiments
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Hospital Clinic of Barcelona
Sexual Dysfunction, Sexual Arousal Disorder
Clitoral Therapy Device in Alleviating Sexual Dysfunction After Genital Mutilation.
The aim of this study to determine the effect of clitoral therapy device EROS device/ on sexual dysfunction after genital mutilation.
- Trial name
- NCT05039775
- Testing
- EROS device, Psychosexual support
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Badr University
Hypoactive Sexual Desire Disorder, Sexual Dysfunctions, Psychological
Ginkgo Biloba: Antidepressant-Induced Sexual Dysfunction
The purpose of this study is to provide the first empirical examination of the effects of Ginkgo biloba (GBE), sex therapy, and a combination of the two on subjective and physiological measures of sexual function in women who are…
- Trial name
- NCT00034021
- Testing
- Ginkgo Biloba, Sex Therapy (genital focus)
- Where
- United States
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Female Sexual Arousal Disorder
Study to Investigate Effect of Sildenafil on Clitoral Engorgement as Measured by Magnetic Resonance Imaging (MRI) in Pre-menopausal Women With Female Sexual Arousal Disorder
The purpose of this study is to investigate the effect of 100 mg sildenafil on clitoral engorgement in pre-menopausal women, as well as examining the safety and toleration of the drug.
- Trial name
- NCT00640458
- Testing
- Sildenafil 100 mg
- Where
- 3 sites in United States, Australia
- Volunteers
- 20 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Arousal Disorders, Sexual
Neuromodulation of the Dorsal Genital Nerve in Persistent Genital Arousal Disorder
The goal of this clinical trial is to learn if neuromodulation of the dorsal genital nerve works to treat symptoms related to Persistent Genital Arousal Disorder in women.
- Trial name
- NemoPGAD (NCT06790563)
- Testing
- Neuromodulation
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Radboud University Medical Center
Hypoactive Sexual Desire Disorder, Female Sexual Arousal Disorder
Effects of Early Abuse on Adult Intimate Relationships
This study is designed to help us better understand the factors that affect the sexual lives of women who have been sexually mistreated during childhood.
- Conditions
- Hypoactive Sexual Desire Disorder, Female Sexual Arousal Disorder, Female Orgasmic Disorder, Major Depressive Disorder
- Trial name
- NCT01803802
- Testing
- Expressive writing
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Female Sexual Arousal Disorder
Multi-Center Study to Evaluate the Efficacy and Safety of Sildenafil Cream (3.6%) in Premenopausal Patients With Female Sexual Arousal Disorder
This study is looking to minimize side effects, while maintaining and potentially improving the therapeutic benefit to patients suffering from Female Sexual Arousal Disorder by providing a topical preparation of Sildenafil…
- Trial name
- RESPOND (NCT04948151)
- Testing
- Sildenafil
- Where
- 51 sites in United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Strategic Science & Technologies, LLC