Clinical trials: Sexual Dysfunction, Physiological
Erectile Dysfunction
Real Life Safety and Efficacy of Vardenafil
In this uncontrolled, non-randomized, prospective, local post-marketed surveillance study, data are obtained on safety and efficacy of LEVITRA® in routine treatment of erectile dysfunction.
- Trial name
- NCT01215409
- Testing
- Vardenafil (Levitra, BAY38-9456)
- Where
- Taiwan
- Volunteers
- 372 people
- Sponsor
- Bayer
Prostate Cancer, Erectile Dysfunction
Intracavernous Bone Marrow Stem-cell Injection for Post Prostatectomy Erectile Dysfunction
Erectile dysfunction is a frequent adverse event after radical prostatectomy for prostate cancer. It is the consequence of penile vascular damage, mainly arterial insufficiency and venous leakage associated with fibrosis of the…
- Trial name
- INSTIN (NCT01089387)
- Testing
- injection of bone marrow mononucleated cells
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Erectile Dysfunction, Lower Urinary Tract Symptoms
Efficacy of Tadalafil (5mg) For Treatment of Early Storage Symptoms and Erectile Dysfunction After Endoscopic Enucleation of Prostate
From previous studies, the investigators found that sexual outcomes after prostate surgery may show insignificant improvement, remain unchanged or deteriorate in non-negligible number of patients especially those with high…
- Trial name
- NCT05955001
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Hypoactive Sexual Desire Disorder, Sexual Dysfunction
A Mindfulness-based Intervention for Older Women With Low Sexual Desire
The overall aim of this research is to adapt and pilot test a multi-component, mindfulness-based behavioral intervention for women age 50 and older with low sexual desire.
- Conditions
- Hypoactive Sexual Desire Disorder, Sexual Dysfunction, Female Sexual Dysfunction
- Trial name
- NCT03232801
- Testing
- mindfulness-based multicomponent intervention, general health education group
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Pittsburgh
Fibromyalgia, Sexual Dysfunction
Fibromyalgia and Sexual Functıonal Dısorder and Sexual Therapy
investigators aim to re-evaluate the findings of Fibromyalgia in patients whose FSFI scores return to normal levels after sexual therapy, by identifying patients with sexual dysfunction according to the FSFI scale applied in…
- Trial name
- NCT05272345
- Testing
- sexual therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Erectile Dysfunction
Evaluate the Safety and Feasibility of Injecting PMD-MSC Into the Penis to Treat the Symptoms of Mild to Moderate ED
Prospective, open-label, non-randomized, study to be conducted at a single center. Ten subjects will undergo an injection of Placental Matrix-Derived Mesenchymal Stem Cells (PMD-MSCs) into the penis for the treatment of mild to…
- Trial name
- PMD-MSC-ED-01 (NCT02398370)
- Testing
- Placental Matrix-Derived Mesenchymal Stem Cells (PMD-MSCs)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Melissa Marchand
Erectile Dysfunction, Azoospermia
Trial to Evaluate Erectile Function, Fertility and Sperm Count in Male Cyclists Compared to Age Matched Controls
Bicycle riding is associated with related diverse urogenital symptoms ranging from genital numbness to erectile dysfunction (ED).
- Trial name
- NCT00282477
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Impotence
Evaluation of the Index of Sexual Life Questionnaire
The purpose of the study is to assess the sensibility of the ISL questionnaire.
- Trial name
- NCT00245596
- Testing
- sildenafil
- Where
- 9 sites in France
- Volunteers
- 120 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Chronic Myelocytic Leukemia, Erectile Dysfunctions
A Potential Relationship Between Treatment With Tyrosine Kinase Inhibitors and Erectile Dysfunction in Male Patients With Chronic Myeloid Leukemia
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by the presence of the Philadelphia chromosome, resulting in the constitutive activation of the BCR-ABL1 tyrosine kinase.
- Conditions
- Chronic Myelocytic Leukemia, Erectile Dysfunctions, CVD - Cardiovascular Disease, Tyrosine Kinase Inhibitor
- Trial name
- ED2024 (NCT07061145)
- Testing
- Tirosin Kinase Inhibitors
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Anxiety Disorder, Cervical Cancer
Scripted Sexual Health Informational Intervention in Improving Sexual Function in Patients With Gynecologic Cancer
This randomized pilot clinical trial studies the feasibility of a pre-operative and/or post-operative scripted sexual health informational intervention and how well it works in improving sexual function in patients with…
- Conditions
- Anxiety Disorder, Cervical Cancer, Endometrial Cancer, Female Reproductive Cancer
- Trial name
- NCT02096783
- Testing
- informational intervention, counseling intervention, questionnaire administration
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Wisconsin, Madison
Ischaemic Heart Disease, Cardiac Arrhythmia
Effects of a Comprehensive Sexual Rehabilitation Programme in Heart Patients
The objective is to investigate the effect of a comprehensive sexual rehabilitation program, consisting of a psycho-educative component and a physical exercise component.
- Conditions
- Ischaemic Heart Disease, Cardiac Arrhythmia, Sexual Dysfunction
- Trial name
- CopenHeartSF (NCT01796353)
- Testing
- sexual rehabilitation, Usual care
- Where
- Denmark
- Volunteers
- 154 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Premature Ejaculation
Study to Evaluate Efficacy and Safety in Males Subjects With Premature Ejaculation
The purpose of this clinical trial is to test an experimental drug therapy called Tramadol Hydrochloride (HCl) Orally Disintegrating Tablets (ODT) ("Tramadol HCl ODT" or the "study drug").
- Trial name
- NCT00983151
- Where
- 38 sites in Austria, Belgium and 5 more
- Volunteers
- 1,050 people
- Sponsor
- Bausch Health Americas, Inc.
Penile Cancer, Erectile Dysfunction
Pharmacological Penile Rehabilitation in the Preservation of Erectile Function Following Bilateral Nerve-Sparing Radical Prostatectomy
When a bilateral nerve-sparing radical prostatectomy (RP) is performed, recovery of erectile function (rigid erections) is reported for up to 80% of patients, who are less than 60 years old.
- Conditions
- Penile Cancer, Erectile Dysfunction, Radical Prostatectomy
- Trial name
- NCT00955929
- Testing
- Sildenafil and questionnaire, Trimix combination (Papavarine 30mg/mL Phentholamine 1mg/mL Prostaglandin E1 10 mcg/mmL) and questionnaires
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Premature Ejaculation
Investigation of the Changes of Brain Structure and Function in Premature Ejaculation Patients and the Effects of Dapoxetine on Central Neural Activity in Premature Ejaculation Patients
Lifelong premature ejaculation (LPE) is a common male sexual dysfunction with a high prevalence in global. Up to now, the etiology of LPE remains unclear.
- Trial name
- NCT03583112
- Testing
- Dapoxetine Hydrochloride Tablet
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Xidian University
Diabetes Mellitus, Type 2, Erectile Dysfunction
Exploratory CSII Trial on Erectile Dysfunction in T2DM Patients
Erectile dysfunction (ED) is a common form of organic sexual dysfunction in males with diabetes, with estimated incidence rates between 35 and 75%.
- Trial name
- ECSIITED (NCT01468519)
- Testing
- Insulin
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Jothydev's Diabetes and Research Centre
Sexual Dysfunction, Major Depressive Disorder
Does Vilazodone Help With Antidepressant-associated Sexual Dysfunction?
This is a three-center, randomized, double-blind, fixed dose study designed to assess the efficacy, safety, and tolerability of a switch to vilazodone for sexual dysfunction associated with use of a selective serotonin reuptake…
- Trial name
- NCT01856127
- Testing
- Vilazodone, Sertraline
- Where
- 3 sites in United States
- Volunteers
- 4 people
- Sponsor
- Thomas Jefferson University
Contraception, Female Sexual Function
The Effect of Sexual Education-Counseling According to PLISSIT in Solving Sexual Problems in Women Using Contraceptive Methods: One Year Follow-up Results
Sexuality is a universal part of human life and is a process in which two people share their emotions, body, soul and pleasures. Although it is a natural part of life, sexuality can be affected by many factors.
- Conditions
- Contraception, Female Sexual Function, Sexual Dysfunction, PLISSIT
- Trial name
- NCT06772883
- Testing
- sexual education and counseling, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Spinal Cord Injuries, Neurogenic Bladder
Below the Belt: Non-invasive Neuromodulation to Treat Bladder, Bowel, and Sexual Dysfunction Following Spinal Cord Injury
Recent findings have demonstrated that electrical stimulation to the spinal cord (i.e. implanted electrodes) can significantly recover bladder, bowel, and sexual function after injury.
- Conditions
- Spinal Cord Injuries, Neurogenic Bladder, Neurogenic Bowel, Spinal Cord Stimulation
- Trial name
- NCT04604951
- Testing
- Transcutaneous Spinal Cord Stimulation
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Erectile Dysfunction
BAY38-9456, 5/10/20mg, vs.Placebo in Erectile Dysfunction
Purpose of the study is:- To assess the efficacy and tolerability of vardenafil in male subjects suffering from erectile dysfunction as compared to placebo- To assess the influence of vardenafil on the self-esteem and…
- Trial name
- NCT00665054
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Where
- 8 sites in Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Bayer
Erectile Dysfunction, Impotence, Vasculogenic
Effectiveness and Safety of Adipose-Derived Regenerative Cells for Treatment of Erectile Dysfunction
Autologous adipose-derived regenerative cells (ADRC) extracted using Celution 800/CRS System (Cytori Therapeutics Inc) from a portion of the fat harvested from the patient's front abdominal wall.
- Trial name
- NCT02472431
- Testing
- Intracavernosal administration of autologous ADRC, Liposuction, ADRC isolation
- Where
- 2 sites in Russia
- Volunteers
- 12 people
- Sponsor
- Central Clinical Hospital w/Outpatient Health Center of Business Administration for the President of Russian Federation