Clinical trials: Sexual Dysfunction, Physiological
Sexual Dysfunction, Endothelial Dysfunction
Effects of Lifestyle-modification Induced Weight Loss on Sexual and Urinary Function, and Quality of Life in Obese Men
This study aims to evaluate the extent to which weight loss of 5-10% from baseline, induced by exercise and diet, improves metabolic and inflammatory profile, endothelial function, erectile function, sexual desire, lower urinary…
- Conditions
- Sexual Dysfunction, Endothelial Dysfunction, Quality of Life, Inflammation
- Trial name
- NCT01554735
- Testing
- Exercise and diet
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Changi General Hospital
Erectile Dysfunction
To Investigate the Efficacy and Safety of Vardenafil in Men With Erectile Dysfunction.
To investigate the efficacy and safety of vardenafil in men with erectile dysfunction.
- Trial name
- NCT00661115
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Where
- 6 sites in India
- Volunteers
- 173 people
- Sponsor
- Bayer
Prostate Cancer, Hypothermia
MRI Temperature Mapping of the Prostate and Urogenital Pelvis Cooled by an Endorectal Balloon
Urinary incontinence and sexual dysfunction are potential side effects for men undergoing the successful removal of the cancerous prostate via surgery.
- Conditions
- Prostate Cancer, Hypothermia, Urinary Incontinence, Erectile Dysfunction
- Trial name
- NCT01979848
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Ankylosing Spondylitis, Sexual Dysfunction
Association of Erectile Dysfunction With Neuropathic Pain, Disease Activity, and Functional Status in Male Patients With Axial Spondyloarthritis: A Cross-Sectional Observational Study
tudy Description Definitions Use this module to describe the study protocol. Required § Required if Study Start Date is on or after January 18, 2017 [*] Conditionally required Brief Summary Use these resources to provide…
- Trial name
- NCT07453628
- Testing
- Anti-TNF agents, NSAIDs, No Treatment (Healthy Controls)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Altuğ Güner
Breast Cancer Female, Sexual Dysfunction
Sexual Dysfunction Check-up in Premenopausal Breast Cancer Survivors Taking Endocrine Therapy: A Cross-Sectional Study
Primary objectives: To estimate Sexual Dysfunction (SD) incidence in premenopausal breast cancer patients treated by surgery and taking endocrine therapy.
- Conditions
- Breast Cancer Female, Sexual Dysfunction, Premenopausal Breast Cancer
- Trial name
- SEXCHECK (NCT06458764)
- Testing
- Questionnaire
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Candiolo Cancer Institute - IRCCS
Erectile Dysfunction
Energy Specific Far Infrared Radiation Treatment for Erectile Dysfunction
A preliminary study to determine the possibility of using far infrared (FIR) radiation to treat impotency.
- Trial name
- NCT00573209
- Testing
- Far Infrared Radiation
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- GAAD Medical Research Institute Inc.
Hypogonadism, Erectile Dysfunction
Efficacy and Safety Evaluating Fispemifene in the Treatment of Hypogonadal Men With Erectile Dysfunction Unresponsive to PDE5 Inhibitors
The objective of the study is to assess and compare the preliminary efficacy, safety and tolerability of fispemifene 300 mg and placebo given once daily for 8 weeks in the treatment of hypogonadal men with erectile dysfunction…
- Trial name
- NCT00415571
- Testing
- Fispemifene (once daily for 8 weeks)
- Where
- 14 sites in United States
- Volunteers
- 72 people
- Sponsor
- QuatRx Pharmaceuticals Company
Premature Ejaculation
Precise Use of Lidocaine Cream to Treat Primary Premature Ejaculation
This study aimed to evaluate the efficacy and safety of applying 5% lidocaine cream to the sensitive area of the glans penis after its precise localization under the penile biological vibration threshold test for the treatment of…
- Trial name
- NCT05749614
- Testing
- Lidocaine cream
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Transsexualism, Surgery
Use of an External Erectile Device in Transgender Man Following Phalloplasty
The purpose of this study is to test whether an external erectile prosthesis (The Elator™) is a feasible alternative to internal erectile prostheses for transgender men who have undergone a phalloplasty with glansplasty and wish…
- Conditions
- Transsexualism, Surgery, Sex Behavior, Erectile Dysfunction
- Trial name
- ProstHEsis (NCT03823014)
- Testing
- Elator
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Peyronie Disease, Erectile Dysfunction
Concurrent Low Intensity Shockwave Therapy on Collagenase Clostridium Histolyticum for Peyronie's Disease
The purpose of this research is to determine whether or not low-intensity shockwave therapy (LiSWT) with Xiaflex treatment will result in greater improvements to the curvature of the penis.
- Trial name
- NCT06065436
- Testing
- Collagenase Clostridium Histolyticum, Storz Duolith LiSWT
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Prostate Cancer, Urinary Incontinence
Rehabilitation and Sex Therapy to Optimize Recovery After Prostate Cancer Treatment
This study is being done at Duke Health and includes adult men who have been treated for localized prostate cancer. The goal is to see if it is feasible and acceptable to offer sex therapy by telehealth after prostate cancer…
- Conditions
- Prostate Cancer, Urinary Incontinence, Erectile Dysfunction
- Trial name
- RESTORE-PC (NCT07685249)
- Testing
- Sex Therapy, Pelvic Floor Physical Therapy, Vacuum Erection Device (VED)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Duke University
Impotence
Effectiveness and Safety of Viagra in Men With ED and LUTS Due to Benign Prostatic Hyperplasia (BPH)
The purpose of this study is to determine whether Viagra is effective in treating erectile dysfunction and lower urinary tract symptoms in men affected by both conditions.
- Trial name
- NCT00143221
- Testing
- Viagra
- Volunteers
- 350 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Erectile Dysfunction
A Study of DA-8159 in Subjects With Erectile Dysfunction
The purpose of this study will be to evaluate the clinical efficacy and safety of DA-8159, an orally administered, potent and selective inhibitor of PDE5, versus placebo for the treatment of subjects with erectile dysfunction…
- Trial name
- NCT00282607
- Testing
- DA-8159
- Where
- 15 sites in United States
- Volunteers
- 300 people
- Sponsor
- Dong-A PharmTech Co., Ltd.
Erectile Dysfunction
POMx In the Treatment of Erectile Dysfunction
POMx can be used as a treatment for erectile dysfunction.
- Trial name
- NCT01220206
- Testing
- One POMx capsule daily, 2 POMx Capsules
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- POM Wonderful LLC
COVID-19, Dyspareunia
Postpartum Sexual Function in Pregnant Women With COVID-19
The aim of this study is to identify women with postpartum sexual dysfunction and dyspareunia risk in the early period and to use the treatment and care services they need effectively.
- Conditions
- COVID-19, Dyspareunia, Postpartum Period
- Trial name
- NCT04389489
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Peyronie Disease
Medical Treatment of Peyronie's Disease With Collagenase Clostridium Histolyticum
Peyronie's disease is the appearance of a fibrosis plaque on the albuginea of the corpora cavernosa, which produces mechanical traction at the time of erection, inducing a deformation/curvature of the erect penis.
- Trial name
- NCT04370652
- Where
- France
- Volunteers
- 156 people
- Sponsor
- University Hospital, Montpellier
Sexual Dysfunction
Linguistic and Cultural Validation in Italian of Female Sexual Function Index (FSFI) Questionnaire
300 italian women will be enroll for linguistic and cultural validation in italian of Female sexual function index (FSFI). This questionnaire is used in most countries to investigate female sexual function.
- Trial name
- NCT01252576
- Where
- Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Club Italiano Femminile di Urologia
Diabetes Mellitus, Non-Insulin-Dependent, Erectile Dysfunction
Evaluation of Advanced Glycation End-products (AGE) and the Erectile Dysfunction (DE) in Diabetic Patients
In diabetics there is an abnormally increased production of AGEs due to hyperglycemia. An association was shown between AGE measured by biopsy (invasive) and DE patients with diabetes (increase of AGE level in the corpora…
- Trial name
- APGADEPD (NCT02770235)
- Testing
- DE assessment, AGE measurement
- Where
- France
- Volunteers
- 97 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Erectile Dysfunction, Impotence
PROPPER Prospective Registry of Outcomes With Penile Prosthesis
The purpose of this observational registry is to collect and better understand "real-world" outcomes for men undergoing penile implant surgery to treat erectile dysfunction.
- Trial name
- PROPPER (NCT01383018)
- Testing
- AMS Penile Prosthesis Devices
- Where
- 11 sites in United States, Canada
- Volunteers
- 1,457 people
- Sponsor
- Boston Scientific Corporation
Sexual Dysfunction, Menopause
Effectiveness of Pelvic Floor Exercises and Sexual Education in Women Over 60
Since the mid-19th century, "old age" has been increasingly recognized as a natural life stage, especially as the human lifespan extends.
- Conditions
- Sexual Dysfunction, Menopause, Pelvic Floor Disorders
- Trial name
- NCT06539897
- Testing
- Sexual education
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Akdeniz University