Clinical trials: Sexual Dysfunctions
Premature (Early) Ejaculation
Comparative Evaluation of Safety and Efficacy of Dapoxetine, Silodosin, and Citalopram in the Management of Premature Ejaculation
This randomized controlled trial evaluated the comparative effectiveness and safety of four pharmacological treatments-Citalopram 20mg, Silodosin 4 mg, Dapoxetine 30 mg on demand, and Dapoxetine 30 mg daily-in men with premature…
- Trial name
- NCT07113145
- Testing
- Oral intake of medication
- Where
- Egypt
- Volunteers
- 450 people
- Sponsor
- Beni-Suef University
Early-stage Breast Cancer, Hypoactive Sexual Desire Disorder
BRE-06: Study to Increase Tolerance to Aromatase Inhibitors for Patients With Early-Stage Hormone Receptor Positive Breast Cancer Who Developed Hypoactive Sexual Desire Disorder
This study is open to women who have early-stage breast cancer and are on aromatase inhibitor (AI) therapy, and who have hypoactive sexual desire disorder (HSDD).
- Conditions
- Early-stage Breast Cancer, Hypoactive Sexual Desire Disorder, Hormone Receptor Positive Breast Carcinoma, Breast Cancer
- Trial name
- NCT07596212
- Testing
- Aromatase Inhibitors, Bupropion, GnRH agonist
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Illinois at Chicago
Sexual Dysfunction, Psychological, Relationship Distress
"Walking Together with Love": a Couples-Based Intervention for Sexual and Relationship Distress in Cancer Patients
Cancer diagnosis and treatment often result in significant changes in body appearance, sexual functioning, and relationship quality, leading to distress for both patients and their partners.
- Conditions
- Sexual Dysfunction, Psychological, Relationship Distress, Cancer
- Trial name
- WTL (NCT06906575)
- Testing
- A Comprehensive Intervention to Improve Sexual and Relationship Well-being for Cancer Patients and Their Partners
- Volunteers
- 100 people
- Sponsor
- Yanfei Jin
Cancer
Caring for the Sexual Health and Wellbeing of Cancer Survivors and Their Intimate Partners: An Anonymous Survey
The aim of this survey study is to provide broad information as reported by cancer survivors and their intimate partners about both their sexual health and their experiences of care from the United Kingdom hospital cancer team…
- Trial name
- NCT06074445
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 169 people
- Sponsor
- Bournemouth University
Erectile Dysfunction
The Pharmacological Basis for the Increase in Visual Time Constants Induced by Single Oral Doses of Sildenafil
Sildenafil and similar drugs have been used for several years to treat erectile dysfunction. It has been noticed that in some people, sildenafil causes a subtle increase in the length of time that visual images that we see are…
- Trial name
- NCT00463957
- Testing
- sildenafil, tadalafil
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
Erectile Dysfunction
Atherogenic Index of Plasma and Tadalafil Response in Erectile Dysfunction
This prospective single-center observational cohort study examined whether baseline atherogenic index of plasma (AIP), calculated from routine triglyceride and high-density lipoprotein cholesterol measurements, was associated…
- Trial name
- NCT07479901
- Testing
- tadalafil
- Where
- Turkey (Türkiye)
- Volunteers
- 176 people
- Sponsor
- Taksim Egitim ve Arastirma Hastanesi
Erectile Dysfunction
Efficacy and Safety of Tadalafil in Hemodialysis Patients
The purpose of this study is to check the safety and efficacy of a pde5 inhibitor, tadalafil, is a special group of patients: Renal chronic patients in hemodialysis treatment.
- Trial name
- NCT00334477
- Testing
- tadalafil
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Pernambuco
Prostate Cancer, Erectile Dysfunction
SAFE Nerve Sparing Guided by Micro-ultrasound (MUS)
Robotic-assisted radical prostatectomy (RALP) has become the standard of care in the management of localized prostate cancer. However, post-prostatectomy erectile dysfunction (ED) and urinary incontinence still pose a challenge…
- Trial name
- NCT06945315
- Testing
- RALP (Robotic-assisted radical prostatectomy), SAFE (Saline assisted fascial engorgement)
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Premature Ejaculation, Stress
Clinical Study to Reduce Premature Ejaculation in Healthy Adult Men
The current study focuses on clinical validation of efficacy of nutraceutical product in management of male health. In healthy adult men with induced premature ejaculation, the introduction of these nutraceuticals has been…
- Trial name
- NCT06571318
- Testing
- Destress and Perform Capsule-U001, Destress and Perform Capsule-I001
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Herbolab India Pvt. Ltd.
Gender Dysphoria
Gender Dysphoria and Transition
Persons with gender dysphoria present the difficulties of access to health care. Little time is devoted to education of health professionals about the care of transgender persons.
- Trial name
- DyGePeT (NCT04265885)
- Testing
- collection of testimonies from transgender people
- Volunteers
- 10 people
- Sponsor
- Central Hospital, Nancy, France
Erectile Dysfunction (ED)
Sano V First In Human Study to Treat ED
A Prospective, First in Human Study to Evaluate the Safety and Performance of a Flow Modification System
- Trial name
- FMS (NCT03651024)
- Testing
- ED surgery
- Volunteers
- 10 people
- Sponsor
- Sano V Pte Ltd
Erectile Dysfunction
Efficacy of Intracavernosal Xeomin With Tadalafil for Mild-Moderate Erectile Dysfunction
Erectile dysfunction (ED) affects approximately 30 million men in the United States and is associated with factors such as aging, smoking, diabetes, hypertension, obesity, and sedentary lifestyle.
- Trial name
- NCT07537855
- Testing
- IncobotulinumtoxinA (100 Units), Tadalafil 20 MG
- Volunteers
- 30 people
- Sponsor
- Northwestern University
Genitourinary Syndrome of Menopause (GSM)
Bipolar Radiofrequency for Genitourinary Syndrome of Menopause
This randomized, sham-controlled clinical trial aims to evaluate the efficacy and safety of bipolar radiofrequency in the treatment of genitourinary syndrome of menopause (GSM) in postmenopausal women.
- Trial name
- BRF-GSM (NCT07419035)
- Testing
- Active bipolar radiofrequency therapy
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Castilla-La Mancha
Erectile Dysfunction
Cavernous Tissue Preservation During Penile Prosthesis Implantation
Spontaneous penile tumescence after penile prosthesis implantation has been previously reported as sporadically occurring during implant surgery.
- Trial name
- CTP (NCT03733860)
- Testing
- Cavernous tissue sparing penile prosthesis implantation, Conventional penile prosthesis implantation, Intracavernosal injection of alprostadil
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Erectile Dysfunction
Randomized Trial of Ropivacaine & Bupivacaine for Inflatable Penile Prosthesis
The purpose of this research is to determine the effects of penile ring block for local anesthesia with liposomal bupivacaine vs ropivacaine mixture in subjects undergoing surgery for Penile Prosthesis Placement.
- Trial name
- ROVEX-IPP (NCT04801368)
- Testing
- Randomization of two local anesthetics.
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Premature (Early) Ejaculation
On-demand Silodosin 4mg vs Dapoxetine 60mg in Treatment of Primary Premature Ejaculation
Both Silodosin 4 mg and Dapoxetine 60 mg significantly improved IELT and sexual function scores in primary PE patients. However, Silodosin exhibited a more favorable tolerability profile with fewer side effects, making it a…
- Trial name
- NCT07081659
- Testing
- sildosin 4mg, dapoxetine 60mg
- Where
- Egypt
- Volunteers
- 95 people
- Sponsor
- Benha University
Obstructive Sleep Apnea, Erectile Dysfunction
Changing Lifestyle in OSA Males Who Suffer Metabolic Syndrome and Impotence: Is There a Response?
The problems like metabolic syndrome and sexual impotence in males with obstructive sleep apnea are common. continuous passive airway pressure (CPAP) is an authorized treatment for this type of apnea but still the recommendations…
- Conditions
- Obstructive Sleep Apnea, Erectile Dysfunction, Metabolic Syndrome
- Trial name
- NCT06960746
- Testing
- lifestyle changing plus CPAP, CPAP
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Erectile Dysfunctions
Daily Tadalafil 5 mg Combined With On-Demand Sildenafil 100 mg for Treatment of Erectile Dysfunction in PDE-5I Non Responder Patients
The goal of this clinical trial is to evaluate whether daily dosing with tadalafil 5 mg combined with on-demand sildenafil 100 mg can improve erectile function in men with erectile dysfunction (ED) who do not respond to PDE5…
- Trial name
- NCT07391579
- Testing
- Tadalafil 5 mg & Sildenafil 100mg
- Where
- 11 sites in Egypt
- Volunteers
- 500 people
- Sponsor
- Mansoura University
Erectile Dysfunction, Post-Op Complication
Low-energy Extracorporeal Shockwave Treatment for Patients After Radical Prostatectomy
The purpose of this project is to verify the relationship between low intensity shock wave treatment (LI-SWT) and increased scores in self-assessment regarding to erectile function (ED) and sexual intercourse, in patients, who…
- Conditions
- Erectile Dysfunction, Post-Op Complication, Prostatic Diseases
- Trial name
- NCT03192917
- Testing
- Low intensity extracorporeal shock wave treatment (LI-ESWT)
- Where
- Denmark
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Erectile Dysfunction
Differential Plasma MicroRNA Profiles in ED and Normal Erectile Function in Older Males
Erectile dysfunction (ED) is strongly associated with aging. With the rapidly expanding aging population and the increase in life expectancy, an increase in the prevalence of ED is expected in the years to come.
- Trial name
- NCT01830049
- Testing
- Take blood
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University