Clinical trials: Sexual Pain Disorders
HIV Infections, Neuropathic Pain
Pain, Inflammation, and Cannabis in HIV
This study will examine how medical cannabis use affects neuropathic pain, inflammation and adverse events in people living with HIV (PLWH) with neuropathic pain.
- Conditions
- HIV Infections, Neuropathic Pain, Cannabis
- Trial name
- PITCH-E (NCT04860089)
- Sponsor
- Montefiore Medical Center
Muscle Damage
Sex Differences in Muscle Damage Following Resistance Exercise With or Without Milk Protein Ingestion
Purpose: To investigate the impact of milk protein ingestion on resistance exercise-induced muscle damage in untrained males and females.
- Trial name
- EIMD-MILK (NCT04986150)
- Testing
- Resistance exercise
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Durham University
Chronic Urogenital Pain
Life-Stress Interview for Women With Chronic Urogenital Pain Conditions
The goal of this study is to test the efficacy, feasibility, and acceptability of providing an experiential assessment interview that targets health, and emotional and stressful experiences in a tertiary care setting specializing…
- Trial name
- NCT02286115
- Testing
- Life-Stress Interview
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Corewell Health East
Female, Dyspareunia
Manual Therapy in Improving Quality of Life in Women With Dyspareunia
Health-related quality of life refers to how a person feels in their daily life. It includes the body, the mind, emotions, daily activities, and relationships with other people.
- Trial name
- MTQoL (NCT07495085)
- Testing
- Experimental Group 1 (GE1) - Fascial Manipulation and Perineal Massage, Experimental group 2 (GE2) - Perineal massage
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- University of Trás-os-Montes and Alto Douro
Coronary Artery Disease, Angina Pectoris
Personalized Risk Evaluation and Diagnosis (Using Corus CAD or ASGES) in the Coronary Tree
The PREDICT study is to develop and validate a diagnostic blood ASGES (age, sex, gene expression score) or Corus CAD for atherosclerotic coronary artery disease (CAD).
- Conditions
- Coronary Artery Disease, Angina Pectoris, Chest Pain, Cardiovascular Diseases
- Trial name
- PREDICT (NCT00500617)
- Testing
- Corus CAD (ASGES)
- Where
- 10 sites in United States
- Volunteers
- 4,350 people
- Sponsor
- CardioDx
Levator Ani Syndrome
A Study Examining the Use of Vaginal Nifedipine With Pelvic Floor Physical Therapy for Levator Myalgia and Pelvic Pain
The objective of this study is to perform a randomized controlled trial among female patients with a diagnosis of pelvic floor hypertonus (extreme muscle tension) with associated pain, dysfunctional voiding, dyspareunia, and/ or…
- Trial name
- NCT01586286
- Testing
- Nifedipine
- Where
- United States
- Sponsor
- Vanderbilt University
Chronic Pain, Hiv
Harmonized Healing: Personalized Music Interventions to Address Chronic Pain in People Living With HIV
The goal of this randomized controlled trial is to understand the feasibility and acceptability of a music-based mobile application to address chronic pain in people with HIV.
- Trial name
- NCT07214077
- Testing
- Harmonized Healing App, Psychoeducation
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
HIV Infections, Peripheral Neuropathy
Study of Pregabalin Versus Placebo in the Treatment of Nerve Pain Associated With HIV Neuropathy
Study to determine if pregabalin is more effective than placebo in treating subjects with nerve pain associated with HIV neuropathy.
- Trial name
- NCT00232141
- Testing
- pregabalin
- Where
- 44 sites in United States, Puerto Rico
- Volunteers
- 302 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Sexual Dysfunction, Hernia, Inguinal
Pain Related Sexual Dysfunction After Laparoscopic Inguinal Hernia Repair
Previous studies have reported that about 3 % of patients who have had open inguinal herniorrhaphy had a visceral, ejaculatory-related pain.
- Conditions
- Sexual Dysfunction, Hernia, Inguinal, Other Chronic Postoperative Pain
- Trial name
- NCT01086007
- Where
- Denmark
- Volunteers
- 1,172 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Vulvodynia, Dyspareunia
Study to Compare the Efficacy of Cognitive-behavioral Couple Therapy and Lidocaine for Provoked Vestibulodynia
Chronic pain problems involving the female reproductive system are major health concerns for all women. Poorly understood, they entail great personal and financial cost.
- Conditions
- Vulvodynia, Dyspareunia, Vestibulodynia
- Trial name
- CBCT-RCT (NCT01935063)
- Testing
- Cognitive Behavioral Couple Therapy, Topical Lidocaine
- Where
- 2 sites in Canada
- Volunteers
- 108 people
- Sponsor
- Université de Montréal
Pelvic Floor Dysfunctions
Effectiveness of Modern Physical Agents in the Treatment of Pelvic Floor Dysfunctions
This clinical trial aims to determine whether adding modern physical agents (high-intensity laser therapy, magnetotherapy, radial shock wave therapy, kinesiotaping) in conjunction with classical rehabilitation interventions…
- Trial name
- EMPHAT-PFD (NCT06800222)
- Testing
- modern agents rehab, classical rehab
- Where
- Lithuania
- Volunteers
- 250 people
- Sponsor
- Lithuanian University of Health Sciences
Sexual Pain Disorders
Cannabis Suppositories and Mindful Compassion Online Groups for Sexual Functioning
Research aim: To determine how an online mindful-compassion intervention adjunct with cannabis suppositories might reduce vaginal pain during sexual intimacy among women post-gynaecological cancer treatment.
- Trial name
- NCT06607835
- Testing
- Mindful- compassion, Mindful-compassion and cannabis suppositories
- Where
- United Kingdom
- Volunteers
- 83 people
- Sponsor
- London Metropolitan University
Chronic Anal Fissure, Hemorrhoidal Disease
Female Sexual Function After Surgery for Benign Perianal Diseases
Benign perianal diseases such as chronic anal fissure, hemorrhoidal disease, and cryptoglandular anal fistula may negatively affect female sexual function through pain, bleeding, discharge, discomfort, and impairment in quality…
- Conditions
- Chronic Anal Fissure, Hemorrhoidal Disease, Cryptoglandular Anal Fistula
- Trial name
- PERISEX (NCT07666035)
- Testing
- Surgical Treatment for Benign Perianal Diseases
- Volunteers
- 120 people
- Sponsor
- Gazi University
Adenomyosis of Uterus
Association of Ultrasound Features of the Myometrium Suggestive of Adenomyosis and Clinical Symptoms
The goal of this study/research is to assess the relationship between ultrasound features of the myometrium suggestive of adenomyosis and clinical symptoms of adenomyosis and to establish a reporting system for adenomyosis…
- Trial name
- MUSA3 (NCT07397715)
- Where
- 5 sites in Belgium, Poland and 2 more
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Swiss GO Trial Group
Vulvo Vaginal Atrophy (VVA)
Proof of Concept Study of Vaginal AZU-101 in Vulvovaginal Atrophy in Postmenopausal Women
Study Objectives: Primary: To assess the safety, tolerability, and systemic pharmacokinetics (PK) of AZU-101 Secondary: To evaluate efficacy of daily vaginal doses of AZU-101 in postmenopausal women on vaginal epithelium
- Trial name
- NCT06197568
- Testing
- Lasofoxifene Tartrate
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Azure Biotech Inc.
Fibromyalgia
The Effect of Core Exercises on Pelvic Dysfunction, Sexual Dysfunction, Pain, Sleep Quality and Quality of Life in Women With Fibromyalgia
In fibromyalgia patients, exercise is needed to reduce symptoms and to prevent muscle weakness with fatigue and pain. Core exercise retrains and strengthens deep postural spinal muscles such as the multifidus and transverse…
- Trial name
- NCT06038214
- Testing
- core exercises, home exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Inonu University
Chronic Pain
Chronic Pain After Childbirth - Caesarean Section Compared to Vaginal Delivery and the Impact of Pre-existing Pain
There is no doubt, that surgery is very often the beginning of a chronic pain disorder. C-section is a worldwide performed operation with increasing trend in the developed countries .This prospective cohort study evaluated the…
- Trial name
- NCT03216044
- Volunteers
- 355 people
- Sponsor
- University Hospital Tuebingen
Endometriosis
Extension to Study on Efficacy and Safety of Linzagolix for the Treatment of Endometriosis-associated Pain
The primary objective of this extension study is to assess the maintenance of efficacy of linzagolix administered orally once daily for up to an additional 6 months (for up to 12 months of treatment in total) in women who have…
- Trial name
- EDELWEISS 5 (NCT04372121)
- Testing
- 75 mg linzagolix tablet, 200 mg linzagolix tablet, Add-back capsule (E2 1 mg / NETA 0.5 mg)
- Where
- 25 sites in United States, Canada and 1 more
- Volunteers
- 30 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Vulvodynia
Efficacy of High Intensity Laser for Provoked Vestibulodynia
This is a multicenter randomized controlled trial (RCT) investigating the effects of laser treatments in women suffering from provoked vestibulodynia compared to a sham-laser treatment.
- Trial name
- Laser_RCT (NCT05597358)
- Testing
- High Intensity Laser Therapy (HILT)
- Where
- 4 sites in Canada
- Volunteers
- 145 people
- Sponsor
- Université de Sherbrooke
Endometriosis
A Phase 3 Study to Confirm the Efficacy and Safety of Linzagolix to Treat Endometriosis-associated Pain
The primary objective of this study is to demonstrate the efficacy and safety of linzagolix administered orally once daily for 3 months at a dose of 75 mg alone or of 200 mg in combination with add-back hormone replacement…
- Trial name
- NCT03986944
- Testing
- 75 mg linzagolix tablet, 200 mg linzagolix tablet, Add-back capsule (E2 1 mg / NETA 0.5 mg)
- Where
- 112 sites in United States, Canada and 1 more
- Volunteers
- 85 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.