Clinical trials: Sexual Risk Behavior, open to volunteers
Paraphilic Disorders, Sexual Addiction
Paraphilic Disorders and Other Conditions With Risk for Sexual Violence: a Case-control Study
The goal of this case-control study is to compare clinical characteristics in help-seeking individuals with paraphilic disorders or sexsomnia (sexual behaviors during sleep- a diagnosis in the American Psychiatric Association's…
- Conditions
- Paraphilic Disorders, Sexual Addiction, Parasomnia
- Trial name
- NCT05861752
- Testing
- Treatment as usual
- Where
- Sweden
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
HIV Infections, HIV Prevention and Care
HealthMpowerment Korea: Pilot Testing the Cultural Adaptation of a Digital HIV Intervention for Men Who Have Sex With Men in South Korea
This study tests a mobile application (app) designed to support sexual health and prevent human immunodeficiency virus (HIV) among young men in South Korea.
- Conditions
- HIV Infections, HIV Prevention and Care, Risk Reduction Behavior, Digital Health
- Trial name
- HMP Korea (NCT07741123)
- Testing
- Bandi Mobile Application (Full Access), Information-Only Mobile Application (Limited Access)
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Seul Ki Choi
Sexual Violence, College Drinking
PAIRS: Friend-Based AISA Intervention
This Phase 2 trial will to examine the efficacy of a brief dyad-based motivational interview (PAIRS MI) delivered to friend dyads with an active treatment-as-usual condition, and a 1-year follow-up.
- Conditions
- Sexual Violence, College Drinking, Behavioral Changes
- Trial name
- PAIRS (NCT07433270)
- Testing
- Friend-Based Motivational Interview, Treatment as usual (TAU)
- Where
- United States
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Alcohol Drinking, Sex, Unsafe
Alcohol and "Heat of the Moment" Sexual Decision Making
HIV transmission remains a significant public health concern, especially among men who have sex with men (MSM). Condomless anal intercourse (CAI) continues to be the major route of transmission for MSM.
- Conditions
- Alcohol Drinking, Sex, Unsafe, Hiv
- Trial name
- NCT05729256
- Testing
- Self-Regulation Intervention, Brief Advice and Information
- Where
- United States
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Parenting, Mental Health Wellness 1
Parenting in 2 Worlds Multisite Trial
This research study will test the effectiveness of a culturally grounded parenting intervention called Parenting in 2 Worlds (P2W).
- Conditions
- Parenting, Mental Health Wellness 1, Substance Use, Risky Health Behavior
- Trial name
- (P2W) (NCT06324318)
- Testing
- Parenting in 2 Worlds (P2W), Healthy Families in 2 Worlds (HF2W)
- Where
- 4 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Help-Seeking Behavior, Pre-exposure Prophylaxis Use
Moon and Sun Brothers: A Community Prevention Intervention (Hermanos de Luna y Sol)
The goal of this quasi-experimental, community intervention is to reduce HIV sexual risk among Latino immigrant bisexual men or men who have sex with men.
- Conditions
- Help-Seeking Behavior, Pre-exposure Prophylaxis Use, Condomless Sex, Risky Health Behavior
- Trial name
- NCT07475702
- Testing
- Moon and Sun Brothers: A Community Prevention Intervention
- Where
- 2 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- San Francisco State University
HIV Infection Primary, Hepatitis, Viral, Human
Seville Cohort of People at Substantial Risk for HIV Infection on Pre-exposure Prophylaxis
Pre-exposure prophylaxis (PrEP) based on tenofovir represents a considerably new preventive intervention that has shown to significantly decrease the number of HIV infections while it enables early diagnosis of HIV and other…
- Conditions
- HIV Infection Primary, Hepatitis, Viral, Human, Sexually Transmitted Infections, Excluding HIV and Hepatitis
- Trial name
- SeVIHPrEP (NCT05492565)
- Testing
- Tenofovir Disoproxil Fumarate 300 MG Oral Tablet
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Emotion Regulation Difficulties; Risky Behaviors (Substance Use, Risky Sexual Behavior, Self-harm, Aggression, Disordered Eating)
The Effects of the PsyPills App on Emotion Regulation and Risk Behaviors in Emerging Adults: A Randomized Clinical Trial
This study aims to investigate the effects of the PsyPills mobile application on improving emotion regulation and reducing risk behaviors among emerging adults.
- Trial name
- NCT07304830
- Testing
- PsyPills, MoodWheel
- Where
- Romania
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
HIV, Sexually Transmitted Infections (STI)
Community Popular Opinion Leader Intervention for HIV Prevention Uptake in Rural South Africa
The Community Popular Opinion Leader (CPOL) is an intervention dveloped in the United States which identifies, trains, and enlists key opinion leaders within communities to deliver messages to peers and help link them to…
- Trial name
- Izinkanyezi (NCT07741474)
- Testing
- CPOL group training
- Where
- South Africa
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Africa Health Research Institute
LGBTQ, Racial Disparities
Lakota Family Acceptance Project Pilot RCT
Although research documents the concerning rates of mental and behavioral health problems (e.g., substance use/initiation) among Indigenous LGBTQ2S+ youth, there is very little known about how to prevent these deleterious issues…
- Conditions
- LGBTQ, Racial Disparities, Family Relationships, Minority Stress
- Trial name
- L-FAP (NCT07865858)
- Testing
- Adapted Lakota Family Acceptance Program
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Fetal Alcohol Spectrum Disorders, Pregnancy
CARRII Native Intervention Optimization Trial
The purpose of this study is to identify the best combination of new intervention components to use with CARRII, the first automated online intervention for alcohol-exposed pregnancies (AEP).
- Conditions
- Fetal Alcohol Spectrum Disorders, Pregnancy, Alcohol-Related Disorders, Drinking, Alcohol
- Trial name
- NCT07547696
- Testing
- CARRII Native Cores
- Where
- United States
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Stigma, Social, Drug Abuse Illicit
Lower Intersecting HIV-related Stigmas to Facilitate Treatment as Prevention (LIFT)
The purpose of this study is to reduce HIV transmission risk among people who inject drugs (PWID) through a multilevel intervention known as LIFT.
- Conditions
- Stigma, Social, Drug Abuse Illicit, HIV (Human Immunodeficiency Virus)
- Trial name
- LIFT (NCT07541131)
- Testing
- LIFT for People Who Use Drugs, LIFT for MMT Providers
- Where
- Kyrgyzstan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
HIV Infections
HIV Prevention Among At-risk Latinos in the Heartland
This study is a randomized controlled trial that evaluates the efficacy of a network intervention to promote regular HIV testing and prevention (risk reduction and PrEP awareness and referrals) among friendship networks of Latino…
- Trial name
- NCT04563715
- Testing
- HIV counseling and testing, Network intervention
- Where
- 3 sites in United States
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
LGBTQ, Racial Disparities
Family Acceptance Project Online (Pilot RCT)
Research shows that sexual and gender minority youth (SGMY) experience high rates of mental health problems and other challenges (e.g., social, academic).
- Conditions
- LGBTQ, Racial Disparities, Family Relationships, Minority Stress
- Trial name
- FAP-O (NCT06839859)
- Testing
- Family Acceptance Project - Online
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Longitudinal Studies, Prospective Studies
Clinical Time and Temporal Dynamics Study (CLIN-TIME)
TH-CLINICAL-TIME is a prospective, longitudinal observational study evaluating how changes in clinical measurements over time may help researchers better understand patient health trajectories and clinically meaningful outcomes.
- Conditions
- Longitudinal Studies, Prospective Studies, Biomarkers, Predictive Value of Tests
- Trial name
- CLIN-TIME (NCT07812831)
- Testing
- No Study-Assigned Intervention
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
HIV Prevention, HIV Risk
Evaluating an Interactive Digital Toolkit for Women's PrEP Implementation
The goal of this study is to test if a Digital PrEP Toolkit helps cisgender women learn about and access PrEP in Alabama and Mississippi. PrEP is a medication that prevents HIV infection.
- Conditions
- HIV Prevention, HIV Risk, Sexual and Reproductive Health
- Trial name
- NCT07292584
- Testing
- Interactive Digital PrEP Toolkit
- Where
- 4 sites in United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
HIV
Behavioral Activation and Risk Reduction for Stimulant Use Among Sexually Active Adolescents and Young Adults
The use of behavioral intervention to reduce stimulant use and concurrent HIV sexual transmission risk.
- Trial name
- IMPACT (NCT06444360)
- Testing
- IMPACT, eSOC
- Where
- 2 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Westat
Arteriosclerosis, Acute Myocardial Infarction
Menopause Related Influences on Leukocyte Distribution, Monocyte Function and Platelet Reactivity
Women and men show marked differences in cardiovascular risk profile and outcome. Women experience fewer cardiovascular events than men before menopause, but this relationship seems to reverse at menopause.
- Conditions
- Arteriosclerosis, Acute Myocardial Infarction, Cardiovascular Events, Menopause
- Trial name
- NCT05985447
- Where
- Germany
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
HIV Infections, Sexual Behavior
Keeping it LITE: Exploring HIV Risk in Vulnerable Youth With Limited Interaction and Digital Health Intervention
Despite advances in HIV diagnostics, care and prevention strategies, infection rates among adolescent and young adult sexual and gender minorities (SGM) continue to rise in the United States (US).
- Trial name
- LITE-2 (NCT05848570)
- Testing
- Keeping it LITE
- Where
- United States
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Hektoen Institute for Medical Research
Behavior
A Chatbot to Reduce Chemsex and HIV-related Risk Behaviors Among Men Who Have Sex With Men
The goal of this clinical trial is to investigate whether receiving chatbot-delivered stage-of-change-tailored online interventions is effective in reducing chemsex among men who have sex with men in Hong Kong.
- Trial name
- NCT07472582
- Testing
- Chatbot-delivered online interventions and online videos, Online videos only
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong