Clinical trials: Sexual Risk Behavior, open to volunteers
HIV Antiretroviral Therapy (ART) Adherence, Alcohol Abuse
Reducing Hazardous Alcohol Use and Optimizing Treatment as Prevention Among Men Living With HIV in Risk Environments
The investigators developed the Kisoboka ("It is possible") Intervention to address limitations of existing evidence-based interventions to optimize treatment as prevention among men living with HIV who drink alcohol at hazardous…
- Conditions
- HIV Antiretroviral Therapy (ART) Adherence, Alcohol Abuse, HIV Infection, Alcohol Use Disorder
- Trial name
- Kisoboka (NCT06771843)
- Testing
- Kisoboka, Behavioral Economics, Motivational Interviewing
- Where
- Uganda
- Volunteers
- 716 people
- Sponsor
- San Diego State University
Sexual Violence, Intimate Partner Violence (IPV)
Evaluation of State-Level Sexual and Gender Minority Laws for the Primary Prevention of Sexual and Intimate Partner Violence Among Sexual and Gender Minority Youth in the U.S.
The goal of this observational study is to learn how state-level laws related to sexual and gender minority (SGM) youth affect the risk of sexual violence (SV) and intimate partner violence (IPV) among sexual minority (SM) youth…
- Trial name
- YAP (NCT07729644)
- Testing
- Enumerated anti-bullying state legislation, Conversion therapy state legislation, Gender-affirming care state legislation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Berkeley
HIV
Behavioral Activation and Risk Reduction for Stimulant Use Among Sexually Active Adolescents and Young Adults
The use of behavioral intervention to reduce stimulant use and concurrent HIV sexual transmission risk.
- Trial name
- IMPACT (NCT06444360)
- Testing
- IMPACT, eSOC
- Where
- 2 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Westat
HIV - Human Immunodeficiency Virus, Suicide Prevention
IDEAS for Hope to Reduce Suicide Risk and Improve HIV Care Engagement in Tanzania
In this project, the investigators will conduct a clinical trial to test the effectiveness and implementation of IDEAS for Hope, a 3-session telehealth counseling intervention delivered by nurses, to reduce suicidality and…
- Trial name
- NCT07459218
- Testing
- IDEAS for Hope, Safety Planning Intervention
- Where
- Tanzania
- Volunteers
- 600 people
- Sponsor
- Duke University
HIV, Sexually Transmitted Infections (STI)
Community Popular Opinion Leader Intervention for HIV Prevention Uptake in Rural South Africa
The Community Popular Opinion Leader (CPOL) is an intervention dveloped in the United States which identifies, trains, and enlists key opinion leaders within communities to deliver messages to peers and help link them to…
- Trial name
- Izinkanyezi (NCT07741474)
- Testing
- CPOL group training
- Where
- South Africa
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Africa Health Research Institute
Arteriosclerosis, Acute Myocardial Infarction
Menopause Related Influences on Leukocyte Distribution, Monocyte Function and Platelet Reactivity
Women and men show marked differences in cardiovascular risk profile and outcome. Women experience fewer cardiovascular events than men before menopause, but this relationship seems to reverse at menopause.
- Conditions
- Arteriosclerosis, Acute Myocardial Infarction, Cardiovascular Events, Menopause
- Trial name
- NCT05985447
- Where
- Germany
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
HIV Infections
HIV Prevention Among At-risk Latinos in the Heartland
This study is a randomized controlled trial that evaluates the efficacy of a network intervention to promote regular HIV testing and prevention (risk reduction and PrEP awareness and referrals) among friendship networks of Latino…
- Trial name
- NCT04563715
- Testing
- HIV counseling and testing, Network intervention
- Where
- 3 sites in United States
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Help-Seeking Behavior, Pre-exposure Prophylaxis Use
Moon and Sun Brothers: A Community Prevention Intervention (Hermanos de Luna y Sol)
The goal of this quasi-experimental, community intervention is to reduce HIV sexual risk among Latino immigrant bisexual men or men who have sex with men.
- Conditions
- Help-Seeking Behavior, Pre-exposure Prophylaxis Use, Condomless Sex, Risky Health Behavior
- Trial name
- NCT07475702
- Testing
- Moon and Sun Brothers: A Community Prevention Intervention
- Where
- 2 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- San Francisco State University
Alcohol Use Disorder, Risk Behavior, Health
Alcohol Misuse, Gut Microbial Dysbiosis and PrEP Care Continuum: Application and Efficacy of SBIRT Intervention
This randomized control trial study among Pre-exposure prophylactic users (PrEP) aims to learn and determine the efficacy of Screening, brief intervention, and referral to treatment (SBRIT) in reducing the risk of alcohol use.
- Conditions
- Alcohol Use Disorder, Risk Behavior, Health, Dysbiosis, HIV Infections
- Trial name
- SEAL (NCT06005298)
- Testing
- Screening, Brief Intervention, Referral to Treatment (SBIRT)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shirish S Barve
Pelvic Floor Dysfunction, Perineal Laceration
Perineal Protection Device for Reducing Perineal Trauma During Vaginal Delivery in First-time Mothers: a Multicenter Randomized Controlled Trial
The goal of this clinical trial is to determine whether using a soft perineal protection device (BabySlide®) in addition to standard manual perineal support during vaginal delivery can reduce the risk of perineal trauma in…
- Conditions
- Pelvic Floor Dysfunction, Perineal Laceration, Wound Dehiscence, Anal Incontinence
- Trial name
- PeriPROTECT (NCT07862660)
- Testing
- Perineal protection device, BabySlide, Standard manual perineal support
- Where
- Sweden
- Volunteers
- 4,226 people
- Sponsor
- Region Skane
Sexually Transmitted Infections
Sexual Behavior and Risk Perception as Factors Associated With STI Incidence in Young Adults
This observational cross-sectional study aims to assess sexual behavior and perception of sexual risk among young adults aged 18 to 25 years in Barcelona, Spain, and to examine their association with self-reported sexually…
- Trial name
- VIBE (NCT07846241)
- Where
- 2 sites in Spain
- Volunteers
- 200 people
- Sponsor
- Parc de Salut Mar
HIV, Risk Behavior
Project SPACE: Testing Daily Text Messages to Reduce Alcohol Use and HIV Risk Behavior
Project SPACE is a micro-randomized trial evaluating the proximal effects theory-based text messages on alcohol use and sexual HIV risk behaviors among HIV-negative young adult men at the day-level.
- Conditions
- HIV, Risk Behavior, Alcohol Abuse
- Trial name
- NCT07769580
- Testing
- CLT- Concrete text messages, CLT- Abstract text messages, Control messages
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Emory University
HIV Prevention, HIV Risk
Evaluating an Interactive Digital Toolkit for Women's PrEP Implementation
The goal of this study is to test if a Digital PrEP Toolkit helps cisgender women learn about and access PrEP in Alabama and Mississippi. PrEP is a medication that prevents HIV infection.
- Conditions
- HIV Prevention, HIV Risk, Sexual and Reproductive Health
- Trial name
- NCT07292584
- Testing
- Interactive Digital PrEP Toolkit
- Where
- 4 sites in United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Behavioural Addiction
NAlmefene Versus Placebo in Addition to Treatment as Usual on Craving in Behavioural Addictions
Behavioural addictions (BAs) [gambling disorder (GD), food addiction (FA), sexual addiction (SA)] may lead to disastrous consequences.
- Trial name
- NABAb (NCT05540288)
- Testing
- Nalmefene
- Where
- 13 sites in France
- Volunteers
- 266 people
- Sponsor
- Nantes University Hospital
Emotion Regulation Difficulties; Risky Behaviors (Substance Use, Risky Sexual Behavior, Self-harm, Aggression, Disordered Eating)
The Effects of the PsyPills App on Emotion Regulation and Risk Behaviors in Emerging Adults: A Randomized Clinical Trial
This study aims to investigate the effects of the PsyPills mobile application on improving emotion regulation and reducing risk behaviors among emerging adults.
- Trial name
- NCT07304830
- Testing
- PsyPills, MoodWheel
- Where
- Romania
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Paraphilic Disorders
Psychological Treatment for Paraphilic Disorders
The goal of this randomized study is to learn if a psychological intervention can treat help-seeking patients with paraphilic disorders. The main questions it aims to answer are: 1.
- Trial name
- NCT06404684
- Testing
- Cognitive behavioral therapy (CBT)
- Where
- Sweden
- Volunteers
- 14 people
- Sponsor
- Region Stockholm
LGBTQ, Racial Disparities
Family Acceptance Project Online (Pilot RCT)
Research shows that sexual and gender minority youth (SGMY) experience high rates of mental health problems and other challenges (e.g., social, academic).
- Conditions
- LGBTQ, Racial Disparities, Family Relationships, Minority Stress
- Trial name
- FAP-O (NCT06839859)
- Testing
- Family Acceptance Project - Online
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Substance Use Disorder (SUD), Sexual and Reproductive Health
WORTH Paths Intervention
Women in the criminal legal system are more likely to experience substance use disorders and unintended pregnancy than women in the general public.
- Conditions
- Substance Use Disorder (SUD), Sexual and Reproductive Health, Sexual Risk Behavior
- Trial name
- NCT06889831
- Testing
- WORTH Paths Digital Intervention, WORTH Paths Wellness Group
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Fairleigh Dickinson University
Obese
Dynamo: a Tailored Lifestyle Promotion Intervention Among Pediatric Patients With Cardiometabolic Risk Factors
The Dyn@mo lifestyle intervention (CHU Sainte-Justine, Quebec, Canada) targets children and adolescents aged 6 to 17 years old with cardiometabolic risk factors, such as obesity, hypertension, disorders in glucose regulation or…
- Trial name
- CIRCUIT (NCT01736748)
- Testing
- Sensor based PA intervention, Traditional PA counseling
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- St. Justine's Hospital
Risk Behavior, Alcohol Use Disorder
TRAC-ER Intervention to Reduce Risky Alcohol Use and HIV Risk
Ecological momentary interventions (EMI), which use phones to deliver messages to reduce alcohol use and related risk behaviors during or prior to drinking events, can help to address triggers in real-time.
- Conditions
- Risk Behavior, Alcohol Use Disorder, HIV Infections
- Trial name
- TRAC-ER (NCT05576350)
- Testing
- Smartphone Based Alcohol Monitoring (SAM), Tracking and Reducing Alcohol Consumption (TRAC), TRAC-ER
- Where
- 2 sites in United States
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- University of Kentucky