Clinical trials: Sexual and Reproductive Health
Contraception, Contraception Behavior
SihatMand Khandaan Healthy Families for Pakistan
The SMK project's primary goal is to improve the status of SRH of women and adolescents within those targeted areas which feature inadequate progress on existing SRH indicators.
- Conditions
- Contraception, Contraception Behavior, Reproductive Behavior, Maternal Behavior
- Trial name
- SMK (NCT06125470)
- Testing
- Uptake of quality Reproductive health and Family planning products, information and Services, Capacity building of facility based and community based healthcare providers (public and private sector) on FP /SRH, Adolescent Engagement
- Where
- 2 sites in Pakistan
- Volunteers
- 236,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Anxiety Disorder, Cervical Cancer
Scripted Sexual Health Informational Intervention in Improving Sexual Function in Patients With Gynecologic Cancer
This randomized pilot clinical trial studies the feasibility of a pre-operative and/or post-operative scripted sexual health informational intervention and how well it works in improving sexual function in patients with…
- Conditions
- Anxiety Disorder, Cervical Cancer, Endometrial Cancer, Female Reproductive Cancer
- Trial name
- NCT02096783
- Testing
- informational intervention, counseling intervention, questionnaire administration
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Wisconsin, Madison
Contraception
Evaluation of a Peer Education Program to Promote Family Planning Among Female Sex Workers in Kenya
-Purpose: To develop and evaluate an intervention designed to improve consistent contraceptive use and dual method use in particular, among female sex workers (FSWs) in Rift Valley Province in Kenya.
- Trial name
- NCT01957813
- Testing
- Lifestyle Counseling, Standard Health Services
- Where
- 2 sites in Kenya
- Volunteers
- 719 people, healthy volunteers welcome
- Sponsor
- FHI 360
HIV Infection, Sexual and Reproductive Health
PrEPared to Choose (PtC) is an Implementation Study of the Delivery of Cabotegravir Long-acting, an Injectable Pre-exposure Prophylaxis (PrEP) Option for HIV Prevention. Injectable PrEP Will be Offered Alongside Oral and Vaginal Ring PrEP From Within a Real-world Context in Cape Town, South Africa.
The goal of this clinical trial is to offer adolescents and young people in Cape Town, South Africa different HIV pre-exposure prophylaxis (PrEP) products and describe how they use these products over an 18-month period.
- Trial name
- PtC (NCT06807736)
- Testing
- Cabotegravir long-acting, Tenofovir emtricitabine, Dapivirine containing vaginal ring
- Where
- South Africa
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Desmond Tutu HIV Foundation
HIV, Sexually Transmitted Infections
Mobile Phone Text Messaging Referral
The study hypothesis is that managed referral of patients at community level (from drug stores) increases uptake of reproductive health (RH) services at dispensary and health centre levels.
- Conditions
- HIV, Sexually Transmitted Infections, Contraception, Pregnancy
- Trial name
- SMS4Health (NCT01746758)
- Testing
- SMS text messaging referral
- Where
- Tanzania
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
Unprotected Sex, Contraceptive Usage
The Evaluation of Pulse: A Mobile Health App and Teen Pregnancy Prevention Program
This study used a randomized controlled design to evaluate the efficacy of a new mobile app, Pulse, in reducing the incidence of unprotected sex among young women.
- Trial name
- NCT04043130
- Testing
- Pulse
- Where
- United States
- Volunteers
- 2,317 people, healthy volunteers welcome
- Sponsor
- Child Trends
Cystic Fibrosis, Patient Engagement
Cystic Fibrosis Reproductive and Sexual Health Collaborative: Building Online Research Partnerships
This is a Patient-Centered Outcomes Research Institute engagement effort aimed at training researchers/providers and patients to work in research teams together online throughout the research process (including: development…
- Trial name
- NCT04999865
- Testing
- 4-part educational program to build patient-engagement methodology capacity
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
mHealth Intervention
Evaluation of a Mobile Health Intervention to Improve Sexual and Reproductive Health Outcomes Among Kenyan Adolescents Living in Urban Informal Settlements
This two-year study evaluates a mobile phone-based comprehensive sexuality education program designed to support adolescent sexual and reproductive health in Kenya, where rates of teenage pregnancy and sexually transmitted…
- Trial name
- NCT07587281
- Testing
- Chatbot providing comprehensive sexuality education plus youth peer facilitators
- Where
- Kenya
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Sexual and Reproductive Health
Electronic Sexual Reproductive Health CDS Tool at the Children's Hospital of Philadelphia
Many studies show early detection of sexual activity in adolescents can improve their health management and that primary care pediatricians would benefit from supports to address adolescent health, including sexual and…
- Trial name
- NCT04974086
- Testing
- Sexually transmitted infection (STI) testing clinical decision support (CDS) tool
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Sexual and Reproductive Health and Rights
Development and Testing of Balika Bodhu
The study aims to generate knowledge on barriers experienced by married adolescent girls (MAGs) in demanding, accessing and practicing their rights regarding their sexual and reproductive health (SRH), including family planning…
- Trial name
- NCT06126770
- Testing
- The social norm intervention
- Where
- Bangladesh
- Volunteers
- 2,918 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Human Papillomavirus Vaccination, Cervical Cancer Prevention
Integrating HPV Education Into School Health Programs in Cambodia and Kenya
The Clinton Health Access Initiative conducted a mixed-methods, school-based interventional study in Cambodia and Kenya to evaluate whether integrating age-appropriate human papillomavirus (HPV) education into existing school…
- Trial name
- NCT07784283
- Testing
- Integrated HPV Education
- Where
- 5 sites in Cambodia, Kenya
- Volunteers
- 9,054 people, healthy volunteers welcome
- Sponsor
- Clinton Health Access Initiative Inc.
HIV Infections
Long-Acting HIV Pre-Exposure Prophylaxis Integrated With Sexual and Reproductive Health - cRCT
The goal of this hybrid (1a) Cluster Randomised Controlled Trial phase 3B trial is to evaluate the effectiveness and implementation of offering a choice of HIV Pre-Exposure Products (PrEP) through community-based sexual and…
- Trial name
- LAPIS (NCT06250504)
- Testing
- APRETUDE (cabotegravir) 600 mg\3 mL, DAPIRING (Dapivirine) 25mg Vaginal Ring, tenofovir disoproxil and emtricitabine
- Where
- South Africa
- Volunteers
- 2,052 people, healthy volunteers welcome
- Sponsor
- Africa Health Research Institute
Reproductive Behavior, Sexual Behavior
Reducing Teen Pregnancy in the Emergency Department
This study will determine the feasibility, acceptability, and potential efficacy of an emergency department-based pregnancy prevention intervention targeting sexually active adolescent female emergency department patients.
- Conditions
- Reproductive Behavior, Sexual Behavior, Adolescent Behavior, Contraception
- Trial name
- ERICA (NCT03866811)
- Testing
- Dr. Erica
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Columbia University
HIV Infection
Community Based Interventions to Improve HIV Outcomes in Youth: a Cluster Randomised Trial in Zimbabwe
A cluster randomised trial to determine the impact of an integrated community-based package of HIV services incorporating HIV testing, linkage to care and ongoing adherence support, combined with sexual and reproductive health…
- Trial name
- CHIEDZA (NCT03719521)
- Testing
- Community-based package of integrated HIV, SRH and general health services
- Where
- 3 sites in Zimbabwe
- Volunteers
- 36,991 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Reproductive Health
Improving the Reproductive Health of Families
This research will assess the effectiveness of a parent- and an adolescent- intervention in lowering risk of STIs, HIV, and unintended pregnancies among Batswana youth.
- Trial name
- NCT03858803
- Testing
- Families Matter 2, Living as a Safer Teen
- Where
- United States
- Volunteers
- 945 people, healthy volunteers welcome
- Sponsor
- Portland State University
Adolescent Behavior, Sexual Behavior
Assessing the Preliminary Effects of a Multisectoral Agricultural Intervention on Adolescent Girls' Health
The goal of this study is to understand how the Shamba Maisha household agricultural and economic intervention impacts the sexual, reproductive, and nutritional health of adolescent girls.
- Conditions
- Adolescent Behavior, Sexual Behavior, Reproductive Behavior
- Trial name
- NCT03741634
- Testing
- Multi-sectoral agricultural intervention
- Where
- 16 sites in Kenya
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Colorectal Cancer, Colorectal Neoplasms
Changes in Reproductive and Sexual Health in People With Early Onset Colorectal Cancer
The purpose of this study is to find out how cancer treatments (chemotherapy and/or radiation therapy) affect reproductive and sexual health in people with early onset colorectal cancer.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Colorectal Carcinoma
- Trial name
- NCT04812912
- Testing
- Hormone biomarker analysis, QoL Questionnaires
- Where
- 7 sites in United States
- Volunteers
- 120 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
HIV Infections, Sexually Transmitted Diseases
MEMA Kwa Vijana Trial: Impact of an Adolescent Sexual and Reproductive Health Intervention in Mwanza, Tanzania
The MEMA kwa Vijana Project is a community randomised trial which aims to assess the impact of a targeted intervention on adolescent sexual and reproductive health in Mwanza Region, Tanzania.
- Conditions
- HIV Infections, Sexually Transmitted Diseases, Pregnancy, Sexual Behavior
- Trial name
- NCT00248469
- Testing
- In-school Sexual Health Education, Youth-friendly health services, Youth condom promotion & distribution
- Where
- Tanzania
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Pregnancy
Sexual Health and Sexual Myths During Pregnancy
The aim of this experimental study is to learn the effects of sexual health education during pregnancy on sexual myths, sexual function and quality of sexual life.
- Trial name
- NCT06735677
- Testing
- sexual health education
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Amasya University
Hiv, AIDS
ALHIV Smartphone Game Study
This is a cluster-randomized controlled trial that aims to conduct comprehensive feasibility testing of a smartphone game in a sample of 120 adolescents living with HIV (ALHIV) ages 15-21 in Kisumu, Kenya, to determine whether…
- Conditions
- Hiv, AIDS, Adolescent Behavior, Treatment Compliance
- Trial name
- NCT06913660
- Testing
- MyGoals, Standard of care
- Where
- Kenya
- Volunteers
- 120 people
- Sponsor
- Emory University