Clinical trials: Sexually Transmitted Disease (STD)
Substance Abuse, HIV Infections
Aripiprazole Treatment for Methamphetamine Dependence Among High-risk Individuals
Studies demonstrate that methamphetamine (meth) use is associated with high-risk sexual behavior among men who have sex with men (MSM), putting meth-using MSM at extraordinarily high risk for transmitting or acquiring HIV.
- Trial name
- NCT00497055
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- San Francisco Department of Public Health
HIV Infections
Drug Interaction Study With Atazanavir Administered With and Without Ritonavir and a Cytochrome P450 Substrate Rosiglitazone
The purpose of this clinical research study is to assess the effect of Atazanavir 400 mg QD and Atazanavir/Ritonavir 300/100 mg QD at steady state on the single dose pharmacokinetics of RGZ in healthy subjects.
- Trial name
- NCT00362726
- Testing
- Rosiglitazone maleate, Atazanavir Sulphate, Atazanavir Sulphate + Rosiglitazone maleate
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Head and Neck Cancer, HPV (Human Papillomavirus)-Associated Carcinoma
Immunologic Responses in HPV-Associated Carcinoma for Patients Receiving Chemoradiation
The primary purpose of this research is to investigate anti-tumor immune responses in patients undergoing chemotherapy and radiation for Head and Neck Cancers.
- Conditions
- Head and Neck Cancer, HPV (Human Papillomavirus)-Associated Carcinoma, Oropharyngeal
- Trial name
- NCT01958515
- Testing
- research blood draw and tissue biopsy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
HIV, Pregnancy Malaria
A Novel Regimen to Prevent Malaria and STI in Pregnant Women With HIV
More than 3 billion people worldwide are at risk of acquiring malaria and pregnant women living with HIV in Africa are at particular risk.
- Conditions
- HIV, Pregnancy Malaria, Sexually Transmitted Infection
- Trial name
- PREMISE (NCT03431168)
- Testing
- Azithromycin/TMPS
- Where
- United States
- Volunteers
- 308 people
- Sponsor
- University of Alabama at Birmingham
Hiv
Exploring a Digital HIV Onward Disclosure Intervention, in People Living With HIV of Sub-Saharan African Ethnicity.
Research has shown that people living with HIV struggle to disclose their HIV status to others, (a process known as self-disclosure or onward disclosure) due to associated challenges, including fear of discrimination from others.
- Trial name
- NCT05804968
- Testing
- Digital HIV Self Disclosure Intervention
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Royal Holloway University
HIV Infections
An Evaluation of Pentoxifylline in HIV-Positive Persons With Symptomatic HIV Infection and a Karnofsky Score > 40 Percent and < 100 Percent
PRIMARY: To determine whether pentoxifylline changes the self-reported measures of quality of life status, using measures of scores from double-blinded drug withdrawal and drug restart periods.
- Trial name
- NCT00002091
- Testing
- Pentoxifylline
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Community Research Initiative of New England
HIV Infections
Evaluating the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of the Monoclonal Antibody PGT121.414.LS Administered Alone and in Combination With VRC07-523LS Via Intravenous or Subcutaneous Infusions in Healthy, HIV-uninfected Adult Participants
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, and antiviral activity of the monoclonal antibody PGT121.414.LS administered alone and in combination with VRC07-523LS via intravenous or…
- Trial name
- NCT04212091
- Testing
- PGT121.414.LS, VRC07-523LS
- Where
- 5 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Intravenous Drug Usage, HIV/AIDS
Building on Needle Exchange to Optimize Prevention & Treatment
There are several biomedical interventions that can help people who inject drugs (particularly those with or at risk for HIV), but these services often do not get to the people most in need.
- Trial name
- NCT03567174
- Testing
- Integrated care van (ICV)
- Where
- United States
- Volunteers
- 720 people
- Sponsor
- Johns Hopkins University
Herpes Zoster, Neuralgia
An Open-Label Extension Study of NGX-4010 for the Treatment of Neuropathic Pain
This study is an open-label, multicenter, extension study for subjects who completed NeurogesX Study C111 and received treatment with NGX-4010 (Capsaicin Patch) within 12 weeks (up to +7days) before entry into Study C114
- Conditions
- Herpes Zoster, Neuralgia, Pain, HIV Infections
- Trial name
- NCT00089557
- Testing
- Capsaicin Dermal Patch
- Sponsor
- NeurogesX
HIV Infections
HIV Risk Reduction in Youth in the Bahamas
This study will examine whether pairing a grade 6 in-school HIV education program and a parent training program will reduce prevalence of behaviors that present high risk of HIV infection in youth in the Bahamas.
- Trial name
- NCT00774592
- Testing
- FOYC, Goal for it (GFI), Wonderous Wetlands
- Where
- United States
- Volunteers
- 1,360 people, healthy volunteers welcome
- Sponsor
- Wayne State University
HIV/AIDS, HIV Infections
Secondary Distribution of HIV Self-tests Through Antenatal Care Clinic Attendees and Index Clients
A three arm cluster randomized trial randomizing government primary health clinics to a) standard of care (SOC) with clinic invitation only; b) standard of care (SOC) and one self-test kit to give to sexual partner (s); c)…
- Trial name
- ANC/FRS (NCT03705611)
- Testing
- HIV self-testing only, HIV self-testing secondary accuracy
- Where
- Malawi
- Volunteers
- 10,000 people
- Sponsor
- London School of Hygiene and Tropical Medicine
HIV Infections, Sexually Transmitted Diseases
Defining the PrEP Care Continuum Among Recently Incarcerated Men at High-Risk for HIV Infection
Background: Several major studies have demonstrated the success of Truvada as pre-exposure prophylaxis (PrEP) in preventing HIV infection.The CDC guidelines recommend PrEP for people who are at elevated risk of HIV including men…
- Trial name
- NCT04240509
- Testing
- Emtricitabine / Tenofovir
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Miriam Hospital
HIV Infection
Immune and Viral Status of HIV-Infected Patients After Stopping Combination Antiretroviral Therapy
This study will examine the effects of increases in HIV blood levels on the immune system. A better understanding of how HIV alters the immune response may lead to development of effective immune-based therapies against the…
- Trial name
- NCT00001899
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Infections, Papillomavirus
Evaluate the Immunogenicity & Safety of GSK Biologicals' HPV Vaccine in Female Subjects Aged 10-14 Years
Human papillomavirus infection has clearly been recognized as the cause of cervical cancer. Indeed, the infection of the cervix by certain oncogenic types of HPV, if not cleared , can lead over time to cervical cancer in women .
- Trial name
- NCT00290277
- Testing
- HPV-16/18 L1/AS04
- Where
- 8 sites in South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Human Immunodeficiency Virus
Development of Method of Fructose Identification in Urine to Detect the Viral Infection
The goal of this research is the attempt to implement a new research method based on modern electrochemistry successes, in particular the development of the polarographic method of fructose and fructose diphosphate identification…
- Trial name
- NCT01638312
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
HIV Infections
Backup With Combivir or Single Dose (SD) Truvada in Order to Avoid Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI) Resistance After SD Nevirapine for the Prevention of Mother-to-child Transmission (PMTCT)
The aim of the study is to find short course alternatives to single dose (sd)nevirapine for the prevention of mother-to-child HIV-transmission with the same or better degree of transmission protection than sd nevirapine but with…
- Trial name
- NCT00346567
- Testing
- Zidovudine and Lamivudine (Combivir), Emtricitabine and Tenofovir (Truvada)
- Where
- Tanzania
- Volunteers
- 566 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Depression, Substance-Related Disorders
Antidepressant Medication for Reducing HIV Risk Behavior in Depressed Intravenous Drug Users
This study will evaluate the effectiveness of antidepressant medication treatment in reducing HIV risk behaviors in intravenous drug users with depression.
- Conditions
- Depression, Substance-Related Disorders, HIV Infections
- Trial name
- NCT00228007
- Testing
- Antidepressant Medication
- Where
- United States
- Volunteers
- 265 people
- Sponsor
- Butler Hospital
Papillomavirus Infections
Immunogenicity and Safety of the 9-valent Human Papillomavirus (9vHPV) Vaccine in Japanese Boys and Girls (V503-066)
The primary objective of this study is the estimation of the human papillomavirus (HPV) 6, 11, 16, 18, 31, 33, 45, 52 and 58 seroconversion at 1 month post last dose (Month 7) following 3 doses and 2 doses of the 9-valent human…
- Trial name
- NCT04772534
- Testing
- 9vHPV vaccine
- Where
- 12 sites in Japan
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
HIV Infections
A Study of Several Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Used Indinavir
To compare the proportion of patients whose plasma HIV-1 RNA is below 500 copies/ml after 16 weeks of treatment. To assess the safety, toxicity, and tolerance of each treatment arm.
- Trial name
- NCT00000892
- Testing
- Ritonavir, Nelfinavir mesylate, Levocarnitine
- Where
- 45 sites in United States
- Volunteers
- 300 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Antiretroviral Therapy for Acute HIV Infection
This study will evaluate the virologic effect, safety and tolerability of Genvoya® in adults during early acute HIV infection.
- Trial name
- NCT03877536
- Testing
- Genvoya 150Mg-150Mg-200Mg-10Mg Tablet
- Where
- Uganda
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
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