Clinical trials: Sexually Transmitted Disease (STD)
Cryptosporidiosis, HIV Infections
Open-Label "Compassionate" Use Study of Spiramycin for the Treatment of Diarrhea Due to Chronic Cryptosporidiosis in Immunocompromised Patients
This protocol provides for the availability of spiramycin under compassionate-use conditions for the treatment of chronic diarrhea due to cryptosporidium in patients with a compromised immune system, thus deriving additional…
- Trial name
- NCT00002062
- Testing
- Spiramycin
- Where
- United States
- Sponsor
- Rhone-Poulenc Rorer
HIV Infections, STDs
Promoting Safer Sex in HIV+ Homosexual and Bisexual Men Who Use Methamphetamine
This project studies the effectiveness of a sexual risk reduction intervention among HIV+ Men who have Sex with Men (MSM) and who use methamphetamine.
- Conditions
- HIV Infections, STDs, Methamphetamine Abuse
- Trial name
- NCT00291512
- Testing
- Theory-based counseling program
- Where
- United States
- Sponsor
- University of California, San Diego
HIV Infection
Stocrin Re-examination Study (0831-028)
This survey is conducted for preparing application materials for re-examination under the Pharmaceutical Affairs Laws and its Enforcement Regulation, its aim is to reconfirm the clinical usefulness of STOCRIN through collecting…
- Trial name
- NCT01065792
- Volunteers
- 728 people
- Sponsor
- Merck Sharp & Dohme LLC
HIV, AIDS
Care4Today v2.0 Application for Improving Adherence to HIV Medications
Although poor antiretroviral (ART) adherence in HIV does not mean a complete lack of therapeutic results, the benefit of ART increases as adherence improves.
- Trial name
- NCT02001064
- Testing
- Care4Today v2.0 mobile application + electronic monitoring of adherence
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Diego
HIV Infections
Antiviral Activity and Safety of Mifepristone at 2 Doses in HIV-1 Infected Subjects
The objective of the study is to determine whether mifepristone (VGX-410) has anti-HIV-1 activity at doses of either 300 mg or 600 mg per day after oral administration for 14 days at each dose level.
- Trial name
- NCT00352911
- Testing
- VGX-410 (Mifepristone)
- Where
- 3 sites in United States
- Volunteers
- 19 people
- Sponsor
- VGX Pharmaceuticals, LLC
Acquired Immunodeficiency Syndrome, HIV Wasting Syndrome
Randomized Placebo-Controlled Study of Aerobic Exercise and Resistance Training Plus Megestrol Acetate for HIV-Wasting
OBJECTIVES: I. Evaluate the effect of aerobic exercise and progressive resistance plus megestrol acetate on lean body mass of patients with human immunodeficiency virus-related weight loss (HIV-wasting). II.
- Conditions
- Acquired Immunodeficiency Syndrome, HIV Wasting Syndrome, HIV Infections
- Trial name
- NCT00004664
- Testing
- megestrol, Exercise
- Volunteers
- 69 people
- Sponsor
- National Center for Research Resources (NCRR)
HIV Infections
A Phase I Multicenter Trial to Evaluate the Safety and Immunogenicity of HIV-1 Recombinant Envelope Glycoprotein gp160
To evaluate the safety and immune response to 160 mcg HIV-1 recombinant envelope glycoprotein gp160. To evaluate the duration of antibody response and its relationship to dose and frequency of inoculation.
- Trial name
- NCT00000757
- Testing
- gp160 Vaccine (MicroGeneSys)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Prevention, HIV Infections
Rectal Microbicide Safety and Acceptability Trial of Topically Applied Tenofovir Compared With Oral Tablet
To date, the majority of microbicide research has focused on the assessment of the safety and effectiveness of vaginal microbicides used for the prevention of HIV transmission via the vaginal compartment.
- Trial name
- RMP02-MTN006 (NCT00984971)
- Testing
- Tenofovir, Open label tenofovir tablet
- Where
- 2 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- CONRAD
HIV Infection
Simple Once Daily Triple Regimen Including Tenofovir, Emtricitabine and Efavirenz in HIV-1 Infected Patients (ANRS 1207)
In the context of Sub-saharian Africa, this trial evaluate one of the most simple treatment available for HIV-1 infected patients.
- Trial name
- NCT00158457
- Testing
- Tenofovir (TDF), Emtricitabine (FTC), Efavirenz (EFV)
- Where
- 2 sites in Senegal
- Volunteers
- 40 people
- Sponsor
- French National Agency for Research on AIDS and Viral Hepatitis
Trauma, Hiv
Developing a Trauma-focused Intervention for Older Adults Living With HIV
Investigators are adapting the LIFT and REFLECT interventions for older adults living with HIV who have been exposed to childhood sexual abuse.
- Conditions
- Trauma, Hiv, Aging
- Trial name
- NCT05287230
- Testing
- CoSHA (Coping with childhood Sexual Abuse, HIV, and Aging), Control
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of South Carolina
HIV Positive, Organ Transplant Recipient
Transplantation and the Use of Raltegravir in HIV-Infected Patients
Raltegravir (RAL) is a preferred option for initial antiretroviral therapy in the most recent HIV Treatment Guidelines and is emerging as a popular choice for use in the specialized population of HIV-infected patients being…
- Conditions
- HIV Positive, Organ Transplant Recipient, Active Wait Listing for Organ Transplant
- Trial name
- NCT01793467
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Duke University
Cognitive Aids
Effect of an Electronic Cognitive Aid Versus Static Cognitive Aid on the Management of a Simulated Crisis
Clinical decision support tools with in the electronic medical record can improve clinical care processes. To date, there is little evidence evaluating crisis management with such decision support tools.
- Trial name
- NCT02440607
- Testing
- Electronic Cognitive Aid, Static Cognitive Aid
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Endeavor Health
Healthy Volunteer
GSK1349572 Proton Pump Inhibitor Drug Interaction and Supratherapeutic Dose Study
GSK1349572 is an integrase inhibitor that is currently being evaluated for the treatment of HIV infection. The primary objective of this study is to determine whether the addition of a proton pump inhibitor, omeprazole, to…
- Trial name
- NCT00942136
- Testing
- GSK1349572, Omeprazole
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
HIV Infections, HIV
Using Mobile Technology and Incentives With Men Who Have Sex With Men and Transgender Women for HIV Prevention
This project called Mobile Technology and Incentives (MOTIVES) aims to increase engagement with HIV prevention information and improve testing frequency among Latino/a men who have sex with men (MSM) and transgender women (TGW).
- Trial name
- MOTIVES (NCT03144336)
- Testing
- Information provision, Weekly quizzes, Rewards for testing HIV-negative
- Where
- United States
- Volunteers
- 217 people
- Sponsor
- RAND
Sexually Transmitted Diseases
A Healthcare Economic Study of the Click Sexual Health Test
This is a multicenter study with a minimum of three CLIA-Waived intended operator sites in which prospectively collected vaginal swab specimens will be evaluated with the Click Sexual Health Test as compared to standard of care.
- Trial name
- HERO (NCT04099199)
- Testing
- Click Sexual Health Test
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Visby Medical
Human Immunodeficiency Virus, Cardiometabolic Risk
The Happy Older Latinos Are Active (HOLA) Health Promotion Study in HIV-Infected Latino Men
The purpose of this study is to examine the feasibility of an intervention to prevent chronic diseases like diabetes, high blood pressure, and obesity in midlife and older Latino adults living with HIV.
- Trial name
- HOLAHIV (NCT03839212)
- Testing
- HOLA Component 1, HOLA Component 2, HOLA Component 3
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Miami
Kaposi's Sarcoma, HIV Positive
A Study to Investigate ALDOXORUBICIN in HIV-infected Subjects With Kaposi's Sarcoma
This is a pilot study to determine the efficacy, kinetics and safety of aldoxorubicin in HIV positive subjects with Kaposi's sarcoma.
- Conditions
- Kaposi's Sarcoma, HIV Positive, AIDS
- Trial name
- NCT02029430
- Testing
- 50 mg/m2 aldoxorubicin, 100 mg/m2 aldoxorubicin, 150 mg/m2 aldoxorubicin
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- ImmunityBio, Inc.
HIV Infections
T-20 With Anti-HIV Combination Therapy for Patients With Prior Anti-HIV Drug Treatment and/or Drug Resistance to Each of the Three Classes of Approved Anti-HIV Drugs
The purpose of this study is to compare the change in viral load (amount of HIV in the blood) of patients who receive T-20 with selected anti-HIV drugs to that of patients who receive only selected anti-HIV drugs.
- Trial name
- NCT00008528
- Testing
- Enfuvirtide
- Where
- 37 sites in United States, Canada
- Volunteers
- 525 people
- Sponsor
- Hoffmann-La Roche
HIV Infection Primary, Hepatitis, Viral, Human
Seville Cohort of People at Substantial Risk for HIV Infection on Pre-exposure Prophylaxis
Pre-exposure prophylaxis (PrEP) based on tenofovir represents a considerably new preventive intervention that has shown to significantly decrease the number of HIV infections while it enables early diagnosis of HIV and other…
- Conditions
- HIV Infection Primary, Hepatitis, Viral, Human, Sexually Transmitted Infections, Excluding HIV and Hepatitis
- Trial name
- SeVIHPrEP (NCT05492565)
- Testing
- Tenofovir Disoproxil Fumarate 300 MG Oral Tablet
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Mycobacterium Avium-intracellulare Infection, HIV Infections
A Study to Learn More About MAC Disease and the Use of Anti-HIV Drugs in Patients With Advanced HIV Infection
The purpose of this study is to determine if infection with Mycobacterium avium complex (MAC) occurs in other parts of the body before it is found in the blood.
- Trial name
- NCT00000895
- Testing
- Nelfinavir mesylate, Nevirapine, Azithromycin
- Where
- 26 sites in United States
- Volunteers
- 85 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
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