Clinical trials: Sexually Transmitted Infection (STI)
HIV Infections
The Safety and Effectiveness of Indinavir Sulfate Plus Efavirenz
To estimate the differences in parameters of antiviral activity and safety between a control regimen of indinavir in combination with DMP 266 and an experimental regimen of higher-dose indinavir in combination with lower-dose DMP…
- Trial name
- NCT00002387
- Testing
- Indinavir sulfate, Efavirenz
- Where
- 8 sites in United States
- Volunteers
- 80 people
- Sponsor
- Merck Sharp & Dohme LLC
HIV Seropositivity
Relationship Between Neuromuscular Fatigue, Perceived Tiredness and Level Of Physical Activity of Patients Living With HIV
Fatigue is a common symptom in people living with HIV (PHAs) that affects all aspects of life . This would include physical deconditioning, a reduction in motor skills .
- Trial name
- ACT PHY HIV (NCT03124914)
- Testing
- Neuromuscular tests
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Acquired Immune Deficiency Syndrome
Immune Reconstitution of Lopinavir/Ritonavir-Based vs Efavirenz-based HAART in Advanced HIV Disease
The ideal anti-HIV medications for patients with advanced HIV disease is unknown. There is evidence that anti-HIV regimens that contain protease inhibitors can enhance immune function better than regimens that do not contain…
- Trial name
- NCT00775606
- Testing
- Lopinavir 400 mg/ritonavir 100 mg, Efavirenz
- Where
- 4 sites in United States
- Volunteers
- 15 people
- Sponsor
- Rush University Medical Center
HIV Infections, Mental Health
Evaluation of Enrollment, Dynamics of Care and Patient Outcomes in the NYS Medicaid HIV Special Needs Plans
The purpose of this study is to find out how people's needs are being met and what people do about problems with treatment, symptoms, substance use, mental health, and social services.
- Trial name
- NCT00577811
- Where
- United States
- Volunteers
- 628 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
HIV Infections
A Study of an Oral Entry Inhibitor, SP01A, in Treatment-Experienced HIV-Infected Patients
One measurement of an HIV infected person's risk of progressing to AIDS is the number of viral particles of HIV in their blood (called a "viral load").
- Trial name
- NCT00113412
- Testing
- SP01A
- Where
- 7 sites in United States
- Volunteers
- 32 people
- Sponsor
- Samaritan Pharmaceuticals, Inc
HIV/AIDS
INcentives and ReMINDers to Improve Long-term Medication Adherence
The study will test the feasibility and acceptability of using text messages and behavioral economics-based incentives to support anchoring Anti-Retroviral Therapy (ART) adherence to an existing routine in order to improve…
- Trial name
- INMIND (NCT05131165)
- Testing
- Daily Text Messages, Incentivization based on timely ART adherence
- Where
- Uganda
- Volunteers
- 166 people
- Sponsor
- RAND
HPV Infections
Reactogenicity Study of Cervarix and Gardasil in UK Adolescent Girls
This is a phase IV study to evaluate the body's immune response of participants to the Cervarix and Gardasil vaccines against the Human Papilloma Virus (HPV) types associated with increased risk of cervical cancer.
- Trial name
- HPV CSP01 (NCT00956553)
- Testing
- Cervarix, Gardasil
- Where
- 3 sites in United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Public Health England
HIV Infections
Effects on the Immune System of Anti-HIV Drugs in Patients Recently Infected With HIV
The purpose of this study is to find out whether these powerful combinations of anti-HIV drugs are safe and effective for use in patients in the early stages of HIV infection and to find out how patients' immune systems react to…
- Trial name
- NCT00001119
- Testing
- Tetanus Toxoid Vaccine, Indinavir sulfate, Lamivudine/Zidovudine
- Where
- 12 sites in United States, Australia
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Ebola Virus Disease, Marburg Virus Disease
Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults
Primary Objective: To evaluate the safety and tolerability of cAd3-EBO-S and cAd3 Marburg vaccines when administered Intramuscular (IM) at a dose of 1 x 10^11 particle units (PU) to healthy adults.
- Trial name
- NCT04723602
- Testing
- cAd3-Marburg, cAd3-EBO-S
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Albert B. Sabin Vaccine Institute
Pneumonia, Pneumocystis Carinii, HIV Infections
A Study of Pentamidine Plus Dapsone in the Prevention of Pneumocystis Carinii Pneumonia (PCP) in HIV-Infected Patients Who Cannot Take Trimethoprim or Sulfonamides
To compare the safety and efficacy of aerosolized pentamidine and dapsone in the prevention of Pneumocystis carinii pneumonia (PCP) in high-risk HIV-infected patients who are intolerant to trimethoprim and/or sulfonamides.
- Trial name
- NCT00001028
- Testing
- Pentamidine isethionate, Dapsone
- Where
- 14 sites in United States
- Volunteers
- 400 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections, Hiv
Diagnosis of HIV and Early Antiretroviral Therapy Initiation Among HIV-1 Infected Infants
The purpose of the study is to test the effect of the Alere™ q HIV-1/2 Detect (diagnostic assay) on uptake of HIV testing among HIV-exposed infants and young children, and health outcomes for HIV-infected infants and young…
- Trial name
- CDC Detect (NCT03133728)
- Testing
- Alere Q Testing
- Where
- 6 sites in Zambia
- Volunteers
- 1,682 people
- Sponsor
- University of Alabama at Birmingham
HIV Infections
The Safety and Effectiveness of a Type of Interleukin-2 Plus Zidovudine Plus Thymosin in HIV-Positive Patients With and Without Symptoms of Infection
To determine the safety of thymosin alpha 1 given twice weekly in a regimen of daily oral zidovudine (AZT) and biweekly polyethylene glycolated interleukin-2 (PEG IL-2).
- Trial name
- NCT00001036
- Testing
- Thymalfasin, Interleukin-2, Polyethylene Glycolated, Zidovudine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections, Hyperlipidemia
IMPAACT P1063: Safety and Effectiveness of Atorvastatin in HIV Infected Children and Adolescents With Hyperlipidemia
Treatment of HIV with combination antiretroviral regimens frequently results in the suppression of HIV viral load, significant immune recovery, and delayed disease progression.
- Trial name
- NCT00663234
- Testing
- Atorvastatin
- Where
- 11 sites in United States
- Volunteers
- 28 people
- Sponsor
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Drug Use, Hepatitis
Low Dead-space Injecting Equipment Distribution Program for People Who Inject Drugs in Low- and Middle-income Countries
Implementation and evaluation of a distribution program for low dead-space syringes/needles (LDSS/N) in Armenia, Georgia, and Tanzania, Egypt, Nigeria, Vietnam, India, Ukraine, and South Africa.
- Conditions
- Drug Use, Hepatitis, Hiv
- Trial name
- NCT06395129
- Testing
- Low dead-space syringes/needles, Hepatitis C Antibody Rapid Diagnostic Test, HIV rapid Diagnostic Test
- Where
- 9 sites in Armenia, Georgia and 1 more
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Médecins du Monde
HIV Infections
A Study of the Effects of Advantage 24 on the Rectum
The purpose of this study is to see if it is safe and acceptable for homosexual male couples, where both partners have the same HIV status, to use Advantage 24 during anal intercourse.
- Trial name
- NCT00000929
- Testing
- Nonoxynol-9
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV/AIDS
HIV Awal (Early) Testing & Treatment Indonesia Project Intervention Phase
This study will be one of the first to systematically evaluate strategies to improve the implementation of a T\&T strategy in a concentrated epidemic in Asia.
- Trial name
- NCT03659253
- Testing
- Oral Fluid Based Self Testing, Simplified ART Initiation, CBO AND BROTHEL-BASED ART SERVICE
- Where
- 4 sites in Indonesia
- Volunteers
- 827 people
- Sponsor
- Gadjah Mada University
HIV Infections, Staphylococcal Infections
Immunologic Predisposition of HIV Patients to Develop Methicillin-Resistant Staphylococcus Aureus (MRSA) Colonization and Infection
The purpose of this study is to investigate the role of T helper 17 cells (Th17) in the pathogenesis of MRSA infections.
- Trial name
- MRSA-2 (NCT00859677)
- Where
- 2 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
HIV (Human Immunodeficiency Virus), Sexually Transmitted Diseases
Reality Check: An HIV Risk Reduction Serial Drama
African Americans have considerably higher rates of HIV infections than do White, Hispanic, Asian, and Native Americans. African Americans accounted for 59% of all diagnoses of HIV infection among youth (13-24 years of age) in…
- Trial name
- RC (NCT03352219)
- Testing
- Reality Check, Physical Activity Attention Control
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
HIV Infections
Reactogenicity and Immunogenicity of Cervico-vaginal CN54gp140-hsp70 Conjugate Vaccine
A vaccine to prevent infection with the Human Immunodeficiency Virus (HIV) is urgently needed. Worldwide, most HIV infections occur through sex between a man and woman.
- Trial name
- TL01 (NCT01285141)
- Testing
- CN54gp140 glycoprotein-hsp70 conjugate vaccine
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- St George's, University of London
HIV Infections, Mental Health
BEYOND Study: Improving HIV Treatment and Well-Being Among Young MSM in Vietnam
The BEYOND Study aims to evaluate HIV treatment outcomes and well-being among young men who have sex with men (YMSM) living with HIV in Ho Chi Minh City, Vietnam.
- Conditions
- HIV Infections, Mental Health, Medication Adherence
- Trial name
- BEYOND (NCT07559266)
- Testing
- NO interventions listed
- Where
- Vietnam
- Volunteers
- 300 people
- Sponsor
- Center for Applied Research on Men and Community Health, Vietnam
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