Clinical trials: Shock
Burns, Sepsis
Comparison Between Interleukin 6 and Procalcitonin in Detecting Sepsis and Incidence of Mortality in Burn ICU Patients
The investigators will compare the efficacy of Interleukin-6 (IL-6) as a better indicator than procalcitonin in burn patients with sepsis or septic shock regarding success of treatment and early ICU discharge.
- Conditions
- Burns, Sepsis, Septic Shock, Death
- Trial name
- NCT06915974
- Testing
- Interleukin 6
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Sepsis, Septic Shock
The Role of Dysfunctional HDL in Sepsis
To determine the role of dysfunctional high density lipoprotein (Dys-HDL) in predicting or mediating progression to chronic critical illness or morbid long-term outcomes in patients being treated for community-acquired or…
- Trial name
- NCT02934997
- Testing
- Observational study
- Volunteers
- 88 people
- Sponsor
- University of Florida
Kidney Stone
A Prospective Observational Comparison of SMP and ESWL for the Treatment of Renal Stones ≥20 mm in Children (IAU-04)
ESWL and PNL are the two treatment modalities for kidney stones greater than 20 mm in the pediatric population. ESWL is non-invasive, does not require anesthesia and inexpensive, but its success rate may be lower, and require…
- Trial name
- NCT04317443
- Testing
- Super-mini percutaneous nephrolithotomy (SMP), Extracorporeal Shock Wave Lithotripsy (ESWL)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- The International Alliance of Urolithiasis
Implantation Rate of Vitrified Blastocysts
Implantation Rate of Vitrified-warmed Collapsed Blastocysts
In our centre, the implantation rate of frozen blastocysts (cryopreserved using vitrification)was 20,3% (Van Landuyt et al. 2011). This implantation rate is lower when compared to data from other observational studies.
- Trial name
- NCT01980225
- Testing
- Collapse
- Where
- Belgium
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Centre for Reproductive Medicine, Belgium
Monomorphic Ventricular Tachycardia
Trial to Evaluate the Efficacy and Safety of Substrate Ablation of Monomorphic Ventricular Tachycardia
To compare the efficacy and safety of substrate-based radiofrequency catheter ablation vs. antiarrhythmic drug therapy in patients with ischemic cardiomyopathy and scar-related sustained monomorphic ventricular tachycardia.
- Trial name
- NCT03734562
- Testing
- Ablation, Antiarrhythmic drug
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Cardiogenic Shock, Cardiogenic Shock Post Myocardial Infarction
Safety and Efficacy of FAP iCDC in Acute Myocardial Infarction With Cardiogenic Shock
To study the safety and efficacy of fibroblast activation protein (FAP)-targeted allogeneic immunosuppressive chimeric antigen receptor-dendritic cell (CAR-DC) in the treatment of acute myocardial infarction with cardiogenic…
- Conditions
- Cardiogenic Shock, Cardiogenic Shock Post Myocardial Infarction, STEMI - ST Elevation Myocardial Infarction
- Trial name
- NCT07380659
- Testing
- FAP allogeneic immunosuppressive CAR-DC
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Septic Shock
Vasopressin for Septic Shock Pragmatic Trial
Life-threatening low blood pressure due to a serious infection is called "septic shock." Septic shock is treated with vasopressors, medications that raise blood pressure.
- Trial name
- VASSPR (NCT06217562)
- Testing
- Vasopressin, Recommendation to use a lower initiation threshold for vasopressin, Recommendation to use a higher initiation threshold for vasopressin
- Where
- 13 sites in United States
- Volunteers
- 3,959 people
- Sponsor
- Intermountain Health Care, Inc.
Cardiogenic Shock
Levosimendan Efficacy for Veno-arterial ECMO Weaning: a Retrospective Study
Failure of Weaning from ECMO is a serious complication, reaching an incidence between 29 and 58%. Inotrops are frequently used to help separating patient from ECMO.
- Trial name
- LEVO-ECMO (NCT03346824)
- Where
- France
- Volunteers
- 65 people
- Sponsor
- University Hospital, Strasbourg, France
EMCO-VA
Vaso-inotropic Score and ECMO-VA Support in Post-cardiotomy Cardiogenic Shock.
Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a well-established lifesaving treatment for refractory cardiogenic shock, with or without concomitant respiratory failure.
- Trial name
- ECMOVIS (NCT05412303)
- Testing
- data collection
- Where
- France
- Volunteers
- 2,769 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Sepsis, Septic Shock
Fast Assay for Pathogen Identification - Quasi-Experimental Intervention Study
The performance and clinical impact of two diagnostic systems will be evaluated using whole blood samples that are collected in parallel with samples for blood culture.
- Conditions
- Sepsis, Septic Shock, Bacteremia
- Trial name
- FAPIC-QE (NCT04103203)
- Testing
- PathoRobot/ Patho-Doc Test result
- Where
- Belgium
- Volunteers
- 1,978 people
- Sponsor
- Hasselt University
Initial Phase of Severe Sepsis and Septic Shock
Population Pharmacokinetics and Monte Carlo Dosing Simulations of Meropenem During the Early Phase of Severe Sepsis and Septic Shock in Critically Ill Patients in Intensive Care Units
This is a prospective, noncomparative study to assess the pharmacodynamics of meropenem during early phase of severe sepsis and septic shock in critically ill patients in an intensive care unit.
- Trial name
- NCT02213796
- Testing
- Meropenem
- Where
- Thailand
- Volunteers
- 9 people
- Sponsor
- Sutep Jaruratanasirikul
Norepinephrine, Hemorrhagic Shock
Norepinephrine in Preperiod of Hypotensive Resuscitation in Hemorrhagic Shock
The aim of this work was to investigate the effects of low dose of norepinephrine in preperiod of hypotensive resuscitation in hemorrhagic shock.
- Conditions
- Norepinephrine, Hemorrhagic Shock, Hypotensive Resuscitation
- Trial name
- NCT06311903
- Testing
- Low dose of Norepinephrine (NE), High dose of Norepinephrine (NE)
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Tanta University
Pancreatitis, Acute
Serum Maresin-1 Predicts the Severity of Severe Acute Pancreatitis
This is a retrospective study about serum Maresin-1 level in different severe acute pancreatitis patients. The investigators want to study the correlation between the level of serum Maresin-1 and the severity of SAP, of course…
- Trial name
- NCT03364920
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Weiqin Li
Severe Sepsis, Sepsis
Early Identification and Effective Management of Pediatric Sepsis
In patients diagnosed as sepsis on PICU admission, early and accurate identification of patients who will develop organ dysfunction (severe sepsis) is critical for effective management and positive outcome.
- Conditions
- Severe Sepsis, Sepsis, Septic Shock
- Trial name
- NCT03996720
- Where
- 4 sites in China
- Volunteers
- 175 people
- Sponsor
- Children's Hospital of Fudan University
Rotator Cuff Lesions
The Clinical and Biological Effect of ESWT With Combined PRP Therapy on Rotator Cuff Lesions
Through the investigators previous study of the effect of transient increased cellular permeability after ESWT, combined ESWT and PRP may have better effect on the treatment of rotator cuff lesions.
- Trial name
- NCT05032924
- Testing
- PPR group with ESWT, PPR group without ESWT, HA group with ESWT
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Chang Gung Memorial Hospital
Hypotension
Association Between Preoperative Shock Index and Hypotension After Spinal Anaesthesia for Non- Elective Caesarean Section
This is a prospective observational study done in parturient planned for non-elective caesarean section. Association between shock index (HR/SBP) and post-spinal hypotension in parturient undergoing non-elective caesarean section…
- Trial name
- NCT04692870
- Where
- Nepal
- Volunteers
- 337 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Evaluation of Acuty Kidney Injury in Children With Hypovolemic Shock
Evaluation Of The Degree Of Kidney Injury in Children With Hypovolemic Shock
To evaluate renal affection and its degree in hypovolemic shocked children
- Trial name
- NCT06612073
- Where
- Egypt
- Volunteers
- 85 people
- Sponsor
- Assiut University
Severe Sepsis, Septic Shock
A Study to Compare the Efficacy and Safety of 2 Dosing Regimens of IV Infusions of AZD9773 (CytoFab™) With Placebo in Adult Patients With Severe Sepsis and/or Septic Shock
The primary purpose of this study to evaluate the effect of two different doses of AZD9773 (CytoFab™) versus placebo on ventilator free days (VFDs) over the first 28 days after the start of dosing with AZD9773 in patients with…
- Trial name
- NCT01145560
- Testing
- AZD9773
- Where
- 52 sites in Australia, Belgium and 5 more
- Volunteers
- 300 people
- Sponsor
- AstraZeneca
Blood Pressure
Hemodynamic Responses in Hemodialysis Patients to Blood Flow Restriction Using Non-pneumatic Anti-shock Garments
Study comparing different groups of people and how they respond to application of the non-pneumatic anti-shock garments. Investigators will divide all recruited participants into three groups based on health status (group 1…
- Trial name
- NCT02915627
- Testing
- Application of Antishock garment
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Erectile Dysfunction
Low-energy Linear Extracorporal Shock Wave Therapy for Erectile Dysfunction.
The purpose of this study is to determine whether extracorporeal shock wave therapy (ESWT) is an effective treatment for erectile dysfunction.
- Trial name
- ESWTvsED (NCT02063061)
- Testing
- ESWT treatment
- Where
- Denmark
- Volunteers
- 126 people
- Sponsor
- Grzegorz Fojecki