Clinical trials: Short Bowel
Healthy Adult
Dietary Fibres on Gut Fermentation
The goal of this clinical trial is to learn if adding a rapidly fermenting fibre to a meal containing a slow fermenting fibre affects gut bacterial fermentation and digestive comfort in healthy adults aged 18 to 85 years.
- Trial name
- NCT07837297
- Testing
- SCF Alone, SCF and FOS (Single Dose), SCF and FOS (Split Dose)
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Bath
Catheter Related Infections, Short Bowel Syndrome
Trial of 70% Ethanol Versus Heparin to Reduce the Rate of Central Line Infections in Children With Short Bowel Syndrome
This study is designed to determine if the use of 70% ethanol lock solution in central lines decreases the rate of central line infections in children with short bowel syndrome.
- Trial name
- NCT01263574
- Testing
- 70% ethanol
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Liver Disease, Short Bowel Syndrome
Investigational Study of Oral Fish Oil in Treating Parenteral Nutrition Associated Liver Disease
The purpose of this study is to investigate the usefulness of oral fish oil(Lovaza)in normalizing liver function in patients who have parenteral nutrition associated liver disease.
- Trial name
- NCT01191177
- Testing
- Lovaza (omega-3-acid ethyl ester), Corn oil
- Where
- United States
- Sponsor
- Boston Children's Hospital
Healthy
Stress-buffering and Sleep Disturbance-resilient Effects of a Dual Bifidobacterium Longum Combination Under Short-term Travel
This study aims to evaluate the effects of a dual Bifidobacterium longum probiotic formulation (dipro-O and dipro-X) on sleep quality, stress responses, and gut microbiota stability in healthy adults during short-term travel.
- Trial name
- NCT07511855
- Testing
- Probiotic
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Min-Tze LIONG
Prematurity, Low Birth Weight Neonates
Metagenomic & Metabolomic Study: Bifidobacterium Probiotic Effects on Gut Microbiota & SCFA in Preterm NICU Infants
One million premature babies die due to prematurity complications, contributing the most to the causes of death in children under 5 years old.
- Trial name
- NCT07213414
- Testing
- Probiotics
- Where
- 3 sites in Indonesia
- Volunteers
- 72 people
- Sponsor
- Hasanuddin University
Colorectal Cancer
Short-term and Long-term Outcomes of Colorectal Cancer Treated With Natural Orifice Specimen Extraction Surgery : a National Registry-based Study
Natural orifice specimen extraction surgery (NOSES) has gained widespread recognition among scholars and has gradually been promoted and popularized around the world.
- Trial name
- NCT06350370
- Testing
- Natural orifice specimen extraction
- Where
- China
- Volunteers
- 8,000 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Short Bowel Syndrome
A Trial to Investigate the Effect of Different Supplements on Fluid and Sodium Status in Short Bowel
Patients with short bowel intestinal failure are recommended to aim for a diet high in energy and protein. Some patients have difficulties in achieving recommended intakes and additional nutrition may be provided by oral…
- Trial name
- NCT02686606
- Testing
- Vital 1.5, Ensure Plus
- Volunteers
- 10 people
- Sponsor
- London North West Healthcare NHS Trust
Celiac Disease
Celiac Disease Among Egyptian Children With Unexplained Short Stature
Detect the prevalence of celiac disease in children with unexplained short stature attended at Assiut University Children Hospital.
- Trial name
- NCT06164548
- Volunteers
- 100 people
- Sponsor
- Assiut University
Colon Cancer, Rectal Cancer
Evaluation of Protein in the Urine in Patients Receiving Bevacizumab
This is a clinical research study to look at the incidence of proteinuria (a condition in which urine contains an abnormal amount of protein) caused by shortened infusions (given into the vein over 10 or 15 minutes) of…
- Trial name
- NCT00849394
- Where
- 3 sites in United States
- Volunteers
- 106 people
- Sponsor
- North Texas Veterans Healthcare System
Executive Function
The Effects of Short-Chain Fatty Acids in Psychosocial Stress-Induced Impairment on Core Executive Functions
The aim of the present trial is to examine core executive functions (EFs) as a functional outcome of attenuating the cortisol response to acute laboratory stress through colonic delivery of an Short Chain Fatty Acids (SCFAs) mix…
- Trial name
- GUTSIE (NCT06286943)
- Testing
- Short Chain Fatty Acids (SCFAs)., Maastricht Acute Stress Task, No-stress control task
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Mixed Fiber Supplementation for Healthy Adults
Assessing the Short-Term Effects of Multi-Fiber Supplementation on Gut Health
This is a randomized, parallel-group interventional study evaluating the short-term gastrointestinal effects of a standardized multi-fiber supplement in healthy adults.
- Trial name
- NCT07787026
- Testing
- Prebiotic
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brown University
Short Bowel Syndrome
Safety and Efficacy Study of Teduglutide in Subjects With Short Bowel Syndrome Who Completed Protocol CL0600-004 (NCT00081458)
The purpose of this clinical study is to evaluate the long-term safety and efficacy of daily administration of teduglutide.
- Trial name
- NCT00172185
- Testing
- teduglutide 0.05 mg/kg/d, teduglutide 0.10 mg/kg/d
- Where
- 21 sites in United States, Belgium and 6 more
- Volunteers
- 65 people
- Sponsor
- Shire
Stress, Healthy Volunteers
Brain Responses to Short-Chain Fatty Acid Intervention
A randomized, triple-blind, placebo-controlled study on the effect of colon-delivered short-chain fatty acids (SCFAs) on neural responses to stress and neuroepigenetics.
- Trial name
- MoodBugs HDAC (NCT06546683)
- Testing
- Short-Chain Fatty Acids
- Where
- Belgium
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Uric Acid Stones
The Effective of Potassium Sodium Hydrogen Citrate in Treating Uric Acid Stones Using Gut Microbiota and Metabolomics.
The goal of this observational study is to investigate the alterations in gut microbiota and metabolites among patients with uric acid stones following the administration of potassium sodium hydrogen citrate.
- Trial name
- NCT06118320
- Testing
- Potassium sodium hydrogen citrate
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Cheng Cao
Short Bowel Syndrome
Effect of the Enteric Hormone Glucagon-Like Peptide (GLP-2) on the Intestinal Blood Flow in Patients With Short Bowel Syndrome
The aim of the study is to investigate the effect of the enteric hormone Glucagon-like Peptide (GLP-2) on patients with short bowel syndrome
- Trial name
- NCT00673751
- Testing
- GLP-2
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Arthritis, Juvenile Rheumatoid, Crohn Disease
Growth Hormone in Children With Juvenile Rheumatoid Arthritis (JRA) and With Crohn's Disease
The investigators hypothesize that the anabolic effects of Genotropin (somatropin) will improve the height and weight of children with inflammatory based chronic illness who have failed to grow despite receiving adequate…
- Trial name
- NCT00511329
- Testing
- somatropin [rDNA origin] for injection
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Nationwide Children's Hospital