Clinical trials: Shortness of Breath
Chronic Obstructive Pulmonary Disease, Interstitial Lung Disease
Move With Air: Exercise Training Study
The purpose of this study is to explore the role of a stream of cool air to the face, through fan-to-face therapy, as a novel adjunct non-pharmacological therapy to enable symptomatic adults with cardiopulmonary disease to…
- Conditions
- Chronic Obstructive Pulmonary Disease, Interstitial Lung Disease, Heart Failure
- Trial name
- NCT05646407
- Testing
- Honeywell HT-900 Turbo Force Air Circulator
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- McGill University
Obesity
Mechanisms of Orthopnea in Stable Obese Patients
The purpose of this study is to study the role of closing volume as a determinant of orthopnea in stable obese subjects. The investigators hypothesized that: (1) increase in closing volume in supine position would be greater in…
- Trial name
- OBAIRWAY (NCT02832609)
- Testing
- Supine
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Chronic Obstructive Pulmonary Disease, Interstitial Lung Disease
Morphine to Maximize the Benefits of Exercise Training in COPD or ILD and Persistent Breathlessness
The purpose of this study is to explore the role of low-dose immediate-release oral morphine as a novel adjunct pharmacotherapy to enable symptomatic adults with advanced chronic obstructive pulmonary disease (COPD) or…
- Trial name
- MorEx (NCT03824834)
- Testing
- Exercise training with morphine
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Dennis Jensen, Ph.D.
Emergencies
Evaluation of the COVID-19 Infection Response in Patients Admitted to the Emergency Department for Dyspnea
This research aims to improve our knowledge of the epidemiology of patients consulting in the COvid-19 Possible REspiratory Units (RECOP unit). Indeed, the epidemic linked to COVID-19 affects France and impacts its health system.
- Trial name
- EPRICOD (NCT04422587)
- Testing
- RECOP unit patient
- Where
- France
- Volunteers
- 1,860 people
- Sponsor
- University Hospital, Toulouse
COPD
Morphine or Fentanyl for Refractory Dyspnea in COPD
Rationale: The most important complaint in severe COPD is dyspnea which is associated with a diminished exercise tolerance, reduced quality of life and can lead to anxiety and depression.
- Trial name
- MoreFoRCOPD (NCT03834363)
- Testing
- Fentanyl, Morphine Retard
- Where
- 10 sites in Netherlands
- Volunteers
- 59 people
- Sponsor
- Huib A.M. Kerstjens
Dyspnea, Unexplained Chronic Dyspnea
Establishing Clinical Utility for a New Diagnostic Test for Patients With Shortness of Breath
This study will collect high-quality data on how practicing specialist physicians, specifically cardiologists and pulmonologists, across the U.S.
- Trial name
- NCT04693793
- Testing
- Education Materials and Janssen Test
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Chronic Bronchitis
Early Mobilization With and Without Chest Physiotherapy in Chronic Bronchitis Patients.
It will be a randomized control trial study in which data are collected from hospital. A sample of 26 patients will divided into two group.
- Trial name
- NCT05646225
- Testing
- chest physiotherapy and early mobilization, early mobilization
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Copd
The Effect of Salt Water Nebulization on Cough, Sputum and Quality of Life in Chronic Obstructive Pulmonary Patients
The aim of this clinical trial is to evaluate the effects of salt-water nebulization on individuals with chronic obstructive pulmonary disease.
- Trial name
- NCT06519188
- Testing
- Nebulization application with 5 ml isotonic sodium chloride
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Ministry of Health, Turkey
Dyspnea
Diagnosing Heart Failure With Preserved Ejection Fraction in Patients With Unexplained Dyspnea (Diagnose-HFpEF)
Invasive diagnosis of heart failure with preserved ejection fraction (HFpEF) in patients with unexplained dyspnea NYHA II-III compared to other diagnostic tools
- Trial name
- NCT04688905
- Testing
- Invasive hemodynamics of left ventricle via conductance catheter at rest, with exercise and with temporary vena cava occlusion
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University of Leipzig
Abdominal Pain, Back Pain
Utility of the History and Physical Exam in the Emergency Department
The study is trying to prove that the history and physical exam (H\&P) in the emergency department is the most important tool in exam of patients.
- Conditions
- Abdominal Pain, Back Pain, Dyspnea, Headache
- Trial name
- NCT01154517
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Henry Ford Health System
Dyspnea
The Impact of Inhaled Furosemide and Perorally Administered Levodropropizine on Dyspnea in Patients With Respiratory Diseases
The goal of this monocentric double blinded cross over trial is to evaluate safety and tolerability of inhaled furosemide in patients with pulmonary diseases and dyspnea.
- Trial name
- INFURO (NCT06252454)
- Testing
- Furosemide 40 mg, Levodropropizine
- Where
- Czechia
- Volunteers
- 102 people
- Sponsor
- University Hospital Hradec Kralove
Asthma, Dyspnea; Asthmatic
Asthma Diagnosis Verified by Lung Function
Guidelines suggests that asthma should not be treated prior to a reversibility test and/or an assessment with peak expiratory flow (PEF) unless there is a clinical urgency for the patient to be treated.
- Conditions
- Asthma, Dyspnea; Asthmatic, Diagnoses Disease
- Trial name
- ADVERT (NCT04652141)
- Testing
- AsthmaTuner
- Where
- Sweden
- Volunteers
- 146 people
- Sponsor
- Björn Nordlund
Dyspnea
PAthwAy of Dyspneic patIent in Emergency in the North-east Region (North-East PArADIsE)
This is an observational retrospective multi-center study in patients managed for acute dyspnea by Emergency department medical team.
- Trial name
- N_E_PARADISE (NCT06235008)
- Where
- France
- Volunteers
- 75,000 people
- Sponsor
- Pr. Nicolas GIRERD
Transient Tachypnea of the Newborn
Inhaled Beta-2 Agonist Versus Epinephrine For Treatment of Transient Tachypnea of Newborn (TTN)
Inhaled Beta-2 Agonist Versus Epinephrine For Treatment of Transient Tachypnea of Newborn: Randomized controlled trial to assess:
- Trial name
- NCT05006235
- Testing
- Epinephrine Inhalation Solution, Salbutamol, Saline Inhalants
- Volunteers
- 135 people
- Sponsor
- Ahmed Noaman
Aging Disorder
Physical Impairments in Elderly Individuals
There are no studies in the literature reporting the dyspnea, posture, strength, physical activity, functional mobility and balance in elderly individuals.
- Trial name
- NCT06267625
- Testing
- Physical Evaluations of individuals
- Where
- Turkey (Türkiye)
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Pulmonary Embolism, Dyspnea
PERCEPIC: PERC Rule Combined With Implicit Low Clinical Probability
PERC rule was created to rule out pulmonary embolism (PE) without further exams, with residual PE risk <2%. Its safety is currently confirmed in low PE prevalence populations as north-American.
- Conditions
- Pulmonary Embolism, Dyspnea, Thoracic Pain
- Trial name
- PERCEPIC (NCT02360540)
- Testing
- Gestalt estimation
- Where
- 12 sites in Belgium, France
- Volunteers
- 1,773 people
- Sponsor
- University Hospital, Angers
Chronic Obstructive Pulmonary Disease, Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Nebulized Verapamil in COPD Exacerbations
This clinical trial evaluated whether adding nebulized verapamil to conventional treatment could improve oxygenation and clinical status in patients hospitalized with an acute exacerbation of chronic obstructive pulmonary disease…
- Trial name
- NCT07866989
- Testing
- Verapamil hydrochloride, Conventional treatment
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Chronic Obstructive Pulmonary Disease (COPD), Dyspnoea
Sports Shoes and the Six-Minute Walk Test in COPD
COPD: A Leading Cause of Respiratory Disability COPD, primarily linked to smoking, affects 3.5 million people in France and causes 15,000 deaths each year.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Dyspnoea, Exercise Intolerance
- Trial name
- ChaussePnee (NCT07445750)
- Testing
- Active Sports Shoes, Usual Shoes
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Dyspnea
Pathway and Urgent caRe of Dyspneic Patient at the Emergency Department in LorrainE District (PURPLE)
This is an observational prospective multicenter study of patients admitted for acute dyspnea in an emergency department of the participating centers in the Lorraine district.
- Trial name
- PURPLE (NCT03194243)
- Where
- 9 sites in France
- Volunteers
- 75,000 people
- Sponsor
- Central Hospital, Nancy, France
Chronic Obstructive Pulmonary Disease
Pennsylvania Study Of Chronic Obstructive Pulmonary Exacerbations
The overall purpose of PA-SCOPE is to determine why black and rural residents of Pennsylvania might be at higher risk for deadly, debilitating, and costly hospitalizations for chronic obstructive pulmonary disease (COPD)- and…
- Trial name
- PA-SCOPE (NCT00774176)
- Where
- 3 sites in United States
- Volunteers
- 1,066 people, healthy volunteers welcome
- Sponsor
- Temple University