Clinical trials: Shoulder Arthroplasty
Shoulder Osteoarthritis
Rehabilitation Following Reverse Total Shoulder Arthroplasty
Reverse total shoulder arthroplasty (RTSA) has been successful in patients with rotator cuff arthropathy, proximal humerus fractures, failed primary total shoulder arthroplasty or failed hemiarthroplasty, and massive irreparable…
- Trial name
- RTSA (NCT03804853)
- Testing
- Rehabilitiation
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- HealthPartners Institute
Shoulder Osteoarthritis
Fixed Inclination Humeral Cut
The purpose of the present study is to determine if a standard humeral cut using a fixed neck shaft angled prosthesis for patients undergoing anatomic TSA is able to restore normal glenohumeral relationships as compared to a…
- Trial name
- NCT03922763
- Testing
- Anatomical cut, Cutting guide
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rothman Institute Orthopaedics
Rotator Cuff Tear Arthropathy, Post Operative Pain
Effect of Radiofrequency of Suprascapular Nerve in Shoulder Reverse Arthroplasty
The purpuse of this study is to asses if the pulsed radiofrecuency of the supraescapular nerve and accesory nerve have the same or superior efectivity controlling the acute postoperative pain than interscalenic braquial plexus…
- Trial name
- NCT05785572
- Testing
- supraescapular nerve radiofrequency, interescalenic braquial plexus
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Hospital Universitario Virgen Macarena
Osteoarthritis, Inflammatory Arthritis
Rotator Cuff Sparing Total Arthroplasty
Design: Prospective, randomized clinical trial, of 120 patients requiring a total shoulder replacement (TSR). Purpose: To collect and evaluate long-term clinical data on patients whose total shoulder replacement (TSR) is…
- Trial name
- NCT01961986
- Testing
- TSR - traditional subscapularis release, TSR - rotator cuff sparing
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- NYU Langone Health
Total Shoulder Arthoplasty
TSA Versus RSA in Patients >75
Total shoulder arthroplasty (TSA) has proven to be a predictable and successful operation for the treatment of symptomatic glenohumeral osteoarthritis (GHOA) with an intact rotator cuff.
- Trial name
- NCT04827277
- Testing
- Reverse Total Shoulder Replacement, Anatomic Total Shoulder Replacement
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Reverse Shoulder Arthroplasty, Depressor Muscle Training
Strengthening Exercises for Humeral Head Depressor Muscles
Postoperative rehabilitation after reverse shoulder arthroplasty aims to improve pain control, range of motion, and functional capacity.
- Conditions
- Reverse Shoulder Arthroplasty, Depressor Muscle Training, Shoulder Rehabilitation
- Trial name
- NCT07309796
- Testing
- Conventional Rehabilitation Group, Depressor Muscle Strengthening Group
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Hacettepe University
Osteoarthritis, Rotator Cuff Tear Arthropathy
Prediction of Development of Scapular Notching Following Reverse Total Shoulder Arthroplasty
The hypothesis is that computer simulated bony impingement of the bone surrounding the spherical glenoid implant (the glenosphere) along the scapular neck on three-dimensional (3-D) computed tomography (CT) imaging analysis is…
- Conditions
- Osteoarthritis, Rotator Cuff Tear Arthropathy, Reverse Total Shoulder Arthroplasty, Scapular Notching
- Trial name
- NCT02052466
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Eric Ricchetti
Staphylococcal Infections, Methicillin-resistant Staphylococcus Aureus
Daptomycin Use for Antimicrobial Prophylaxis in Methicillin Resistant Staphylococcus Aureus (MRSA) Colonized Adult Patients Undergoing Primary Elective Hip, Knee, or Shoulder Arthroplasty
This study will evaluate the safety and effectiveness of daptomycin, an antibiotic compared to another one which is vancomycin when given around the time of joint replacement surgery.
- Trial name
- NCT01196169
- Testing
- Daptomycin, Vancomycin
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Mountain Home Research & Education Corporation
Surgery, Surgical Site Infection
SURGX Antimicrobial Gel Versus Povidone-iodine Skin Incision Prep in Total Shoulder Arthroplasty
Comparing the growth of intra-operative tissue cultures of Cutibacterium Acnes after primary shoulder replacement when using a no-prep control group versus antimicrobial wound gel versus betadine applied to the skin layer after…
- Conditions
- Surgery, Surgical Site Infection, Cutibacterium Acnes, Prosthetic-joint Infection
- Trial name
- NCT05919888
- Testing
- Povidone-Iodine, SURGX Wound Gel
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- St. Louis University
Glenohumeral Arthritis, Total Shoulder Arthroplasty
Pain Management After Total Shoulder Arthroplasty
The purpose of the study is to determine if pain management after total shoulder arthroplasty is more efficacious with ultrasound guided, continuous Interscalene block or with local tissue infiltration with liposomal bupivacaine.
- Trial name
- NCT03219983
- Testing
- Ropivacaine, liposomal bupivacaine
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- The Christ Hospital
Arthroplasty, Replacement, Shoulder, Shoulder Osteoarthritis
Does BIO-RSA Provides Superior Clinical Outcome Compared to Conventional RSA?
The goal of this clinical trial is to compare two different types of reverse shoulder replacements. Researchers will compare a conventional reverse shoulder replacement with a lateralized reverse shoulder replacement to see if…
- Trial name
- CARS-1 (NCT06025331)
- Testing
- BIO-RSA, RSA
- Where
- 2 sites in Norway
- Volunteers
- 130 people
- Sponsor
- Lovisenberg Diakonale Hospital
Rotator Cuff Tear, Proximal Humerus Fractures
Clinical Outcome Comparison Between Medial and Lateral Offset Reverse Shoulder Arthroplasty
The purpose of this study is to prospectively evaluate two FDA approved implant designs for the Tornier Reverse Shoulder arthroplasty. The small difference in design is the amount of offset each implant has.
- Conditions
- Rotator Cuff Tear, Proximal Humerus Fractures, Malunions, Chronic Proximal Humerus Dislocations
- Trial name
- NCT01086202
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Arthroplasty, Replacement, Shoulder
Evaluation of Regeneten Augmentation for Subscapularis Healing After Total Shoulder Arthroplasty (RESTOR)
The purpose of this study is to evaluate whether augmentation of subscapularis repair with the Regeneten implant after anatomic total shoulder arthroplasty (TSA) can improve rates of subscapularis healing and improve clinical…
- Trial name
- NCT04861714
- Testing
- Regeneten, Standard repair
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Ohio State University
Shoulder Fractures, Shoulder Arthritis Osteoarthritis
Zimmer Biomet Shoulder Arthroplasty PMCF Study
This is a multicenter, prospective, non-controlled post market surveillance study. The objectives of this study are to confirm the safety, performance, and clinical benefits of the Zimmer Biomet Shoulder Arthroplasty systems in…
- Conditions
- Shoulder Fractures, Shoulder Arthritis Osteoarthritis, Shoulder Injury, Shoulder Pain
- Trial name
- NCT06920459
- Testing
- Alliance™ Glenoid
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 50 people
- Sponsor
- Zimmer Biomet
Total Shoulder Arthroplasty
Diagnostic Accuracy of Synovial Biopsy for Implant-Related Shoulder Infections
The purpose of this study is to determine the efficacy of retrieving tissue samples via an x-ray guided needle that is inserted into the infected tissue in the shoulder.
- Trial name
- NCT02143245
- Testing
- Synovial Biopsy, Open Tissue Biopsy
- Where
- 4 sites in Canada
- Volunteers
- 118 people
- Sponsor
- Ottawa Hospital Research Institute
Shoulder Arthroplasty, Positive C. Acnes Culture
Post-incision Antimicrobial Wash vs C. Acnes in Shoulder Arthroplasty
The purpose of this randomized controlled trial is to determine the effect of post-incision wash using various novel antimicrobial solutions on the rate of positive C.
- Trial name
- NCT06831422
- Testing
- Povidone-Iodine, Hydrogen Peroxide, Xperience Antimicrobial Wash
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Henry Ford Health System
Shoulder Arthritis
Study of Personalized Instrument in Total Shoulder Arthroplasty The P.I.T.S.A. Study
Total shoulder arthroplasty is an effective procedure to improve patients function and to relieve shoulder pain in cases of glenohumeral arthritis. The main challenge of this procedure is implanting the glenoid component.
- Trial name
- PITSA (NCT03839758)
- Testing
- TSA standard, RTSA standard, TSA Blueprint
- Where
- Canada
- Volunteers
- 112 people
- Sponsor
- Université de Montréal
Chronic Pain
Chronic Pain After Shoulder Arthroplasty
Chronic pain is relatively common after different types of surgery. The investigators intend to study prevalence, characteristics and risk factors of chronic pain after shoulder arthroplasty, focusing on neuropathic pain…
- Trial name
- NCT01900223
- Volunteers
- 786 people
- Sponsor
- Karen Bjørnholdt
Shoulder Osteoarthritis, Arthropathy Shoulder
Scapular Positioning in Standing Position Using Sonography
The objective of this study is to analyse the positioning of the scapula in standing position and compared to the supine position (CT scan) in 3 dimensions (3 rotations of the scapula) using a non-radiant, portable system…
- Trial name
- 3S (NCT04449146)
- Testing
- Scapular positioning in Standing position using Sonography
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Brest
Primary Osteoarthritis, Secondary Osteoarthritis
Clinical and Radiological Outcomes of Medacta Shoulder System (BE)
This is a post-market surveillance study on Medacta Shoulder System
- Conditions
- Primary Osteoarthritis, Secondary Osteoarthritis, Rotator Cuff Tear Arthropathy, Rheumatoid Arthritis Shoulder
- Trial name
- NCT05002335
- Testing
- Medacta Shoulder System
- Where
- 3 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- Medacta International SA