Clinical trials: Shoulder Arthroplasty
Proximal Humerus Surgery, Rotator Cuff Surgery
Effect of Liposomal Bupivacaine and Bupivacaine Hydrochloride for Superior Trunk Block of the Interscalene Brachial Plexus on Postoperative Diaphragmatic Function and Analgesia
To compare the effects of 1.33% liposomal bupivacaine versus 0.375% bupivacaine hydrochloride for superior trunk block of the interscalene brachial plexus on postoperative diaphragmatic function and analgesic efficacy in shoulder…
- Conditions
- Proximal Humerus Surgery, Rotator Cuff Surgery, Shoulder Arthroplasty, Shoulder Arthroscopy
- Trial name
- NCT07587203
- Testing
- Liposomal bupivacaine, Bupivacaine Hydrochloride
- Where
- 3 sites in China
- Volunteers
- 184 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Total Shoulder Arthroplasty
Glenosphere Size and Scapular Notch in RSA, Prospective Randomized Study
Scapular notch can be reduced by using bigger glenospheres but in some patients it cannot be implanted because of small size. If small size of glenosphere is used then scapular notch may increase.
- Trial name
- GSSNRSA (NCT03730597)
- Testing
- reverse shoulder arthroplasty
- Volunteers
- 95 people
- Sponsor
- Hospital del Mar
Proximal Humeral Fractures
Effect of Osteosynthesis, Primary Hemi-arthroplasty, and Non-surgical Management for Fractures of the Proximal Humerus
Displaced four-part fractures are among the most severe injuries of the proximal humerus. The optimal treatment is disputed and published data are inadequate for evidence-based decision making.
- Trial name
- NCT00835562
- Testing
- Non-surgical management, Osteosynthesis, Hemiarthroplasty
- Where
- Denmark
- Volunteers
- 162 people
- Sponsor
- Herlev Hospital
Total Shoulder Arthroplasty
Interscalene Dynamometer Pilot Study
Total shoulder arthroplasty (shoulder replacement) can cause severe postoperative pain. Commonly, patients receive general anesthesia with interscalene block (injection of local anesthetic or numbing medicine near nerves in the…
- Trial name
- NCT01550952
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Hospital for Special Surgery, New York
Pain, Postoperative
Analgesic Efficacy of Interscalene Nerve Block Versus Local Infiltration Analgesia Following Total Shoulder Arthroplasty
Total shoulder arthroplasty (TSA) is considered to be a major surgical procedure resulting in severe postoperative pain, especially in the first 48 hours after surgery.
- Trial name
- NCT02876055
- Testing
- Single shot interscalene nerve block, Continuous interscalene nerve block, Local Infiltration Analgesia (LIA)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Pain, Postoperative
Pain Management After Shoulder Prosthesis: A Clinical Trial of Nerve Block and Local Infiltration
The purpose of this study is to determine the efficacy of local infiltration analgesia as compared to 48-hour interscalene block in treating pain after shoulder arthroplasty.
- Trial name
- NCT01362075
- Testing
- Local infiltration analgesia, Interscalene catheter
- Where
- 2 sites in Denmark
- Volunteers
- 74 people
- Sponsor
- Horsens Hospital
Rotator Cuff Tear Arthropathy
Impact of Humeral Component Version on Outcomes Following RTSA
The proposed study is a prospective, single-blinded, randomized trial to investigate the impact of humeral component version on shoulder range of motion and patient reported functional outcomes following reverse total shoulder…
- Trial name
- NCT03111147
- Testing
- 0 degrees humeral component version, 30 degrees humeral component retroversion
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Corewell Health East
Arthroplasty
Arthroplasty Cements Outcomes - A Post-market Follow-up
A Post-Market Clinical Follow-Up (PMCF) Study to collect clinical data on safety and performance of all Teknimed Arthroplasty range of products: CEMFIX® and GENTAFIX® bone cements families and CEMSTOP® cement restrictor, and all…
- Trial name
- NCT06354543
- Testing
- Cemented joint arthroplasty
- Where
- 10 sites in France, Italy
- Volunteers
- 1,050 people
- Sponsor
- Teknimed
Osteoarthritis
Lesser Tuberosity Osteotomy for Subscapularis Repair
The primary objective of this study is to assess the clinical effectiveness of two different techniques used for subscapularis tendon repair during total shoulder replacement.
- Trial name
- NCT02762903
- Testing
- TSA with tenotomy technique, TSA with lesser tuberosity osteotomy technique, Shoulder prosthesis
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Columbia University
Rotator Cuff Tears of the Shoulder
Integrity Implant System Post Market Clinical Follow-Up Study
The study design is a prospective, multi-center, single-arm, non-randomized post market clinical follow-up study to confirm the performance, safety and clinical benefit of the Integrity Implant System when used for rotator cuff…
- Trial name
- NCT06741527
- Testing
- Integrity Implant System
- Where
- 9 sites in United States
- Volunteers
- 150 people
- Sponsor
- Anika Therapeutics, Inc.
Shoulder Arthroplasty
Total Shoulder Arthroplasty Multi-Center Registry
The objective of the study is a multi-center prospective registry to collect clinical outcomes of anatomic and reverse total shoulder arthroplasty.
- Trial name
- NCT03511586
- Where
- 27 sites in United States, Germany and 2 more
- Volunteers
- 2,500 people
- Sponsor
- Arthrex, Inc.
Arthropathy Shoulder
Determination of Scapulothoracic and Glenohumeral Angles by Imaging in Patients After Shoulder Arthroplasty (SCAP-imag)
The shoulder is a site particularly affected by osteoarthritis since it affects up to 7% of the population aged over 65. To deal with osteoarthritis, total shoulder prosthesis is an increasingly used solution.
- Trial name
- SCAP-imag (NCT06877936)
- Testing
- EOS exam, Questionnaires Constant et ASES
- Where
- France
- Volunteers
- 25 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Shoulder Impingement
Range-of-motion Analysis of Reverse Shoulder Arthroplasty
Limited range-of-motion (ROM) is a common problem after reverse shoulder arthroplasty (RSA). The occurrence and magnitude depend on both surgical and patient-related factors.
- Trial name
- ROM (NCT04633083)
- Testing
- Data collection
- Where
- Belgium
- Volunteers
- 18 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Total Shoulder Arthroplasty
Analgesia After Total Shoulder Arthroplasty
The purpose of this study is to determine which medication(s) should be included in the interscalene nerve block (an injection of local anesthetic [numbing medicine] near nerves in the shoulder) for patients undergoing total…
- Trial name
- NCT01782872
- Testing
- Interscalene Block (ISB) - 0.375% Ropivacaine + additives, Interscalene Block (ISB) - 0.2% Ropivacaine + additives, Interscalene Block (ISB) - 0.1% Ropivacaine + additives
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Hospital for Special Surgery, New York
Arthroplasty, Replacement, Shoulder
Intravenous Dexamethasone Administration in Patients Undergoing Total Shoulder Arthroplasty
The aim of the study is to evaluate if intravenous steroid supplementation can provide advantages over routine analgesia protocols in terms of post-operative symptoms (pain and nausea), length of hospital stay, shoulder range of…
- Trial name
- NCT04507412
- Testing
- dexamethasone
- Where
- Switzerland
- Volunteers
- 74 people
- Sponsor
- Christian Candrian
Shoulder Osteoarthritis
Clinical Evaluation of Reverse Versus Anatomic Shoulder Arthroplasty Techniques in the Treatment of Osteoarthritis
Osteoarthritis (OA) is the most common form of arthritis, affecting millions of people worldwide and it is common in an aging population.
- Trial name
- CERVASA (NCT05395819)
- Testing
- Reverse Total Shoulder Arthroplasty (RTSA), Total Shoulder Arthroplasty (TSA)
- Where
- 7 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Osteoarthritis
Effectiveness of Hemi- Versus Total Shoulder Arthroplasty Using Implants of the "Epoca" System
The clinical question on whether or not to replace the glenoid component in patients with a degenerative shoulder disease, has not been answered yet in a randomized study with enough statistical power.
- Trial name
- Epoca H vs T (NCT01288066)
- Testing
- Hemiarthroplasty, Total arthroplasty
- Where
- 4 sites in Austria, Germany and 1 more
- Volunteers
- 76 people
- Sponsor
- AO Innovation Translation Center
Total Shoulder Arthroplasty
Exparel for Total Shoulder Arthroplasty
The primary objective of this study is to determine if Exparel leads to better pain scores at 24, 48 and 72 hours after Total Shoulder Arthroplasty (TSA) compared to a pain pump.
- Trial name
- NCT04364867
- Testing
- Exparel, Pain Pump
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Norton Healthcare
Osteoarthritis: Shoulder
Local Intraoperative Analgesic Injection Versus Single Injection Interscalene Nerve Block in Patients Undergoing TSA
A non-blinded randomized controlled trial, in which participants undergoing primary reverse or total shoulder arthroplasty are randomly assigned to one of two treatment groups.
- Trial name
- NCT02695758
- Testing
- Interscalene brachial plexus block, bupivacaine extended-release liposome injection
- Volunteers
- 156 people
- Sponsor
- Rothman Institute Orthopaedics
Arthroplasty Complications, Shoulder Osteoarthritis
Is MIO-RSA Noninferior to BIO-RSA When it Comes to Mechanical Implant Stability?
This clinical trial will investigate whether metallic lateralization in reverse shoulder arthroplasty is as stable as bony lateralization during the first two postsurgical years, measured with CT-based motion analysis (CTMA).
- Trial name
- CARS-2 (NCT06025448)
- Testing
- BIO-RSA, MIO-RSA
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Lovisenberg Diakonale Hospital