Clinical trials: Shoulder Surgery
Acute Pain
Liposome Bupivacaine Interscalene Total Shoulder
This is a randomized prospective outcomes study comparing two groups of patients. One group will receive liposomal bupivacaine plus bupivacaine and the other will receive bupivacaine alone in interscalene blocks when undergoing…
- Trial name
- NCT03587636
- Testing
- liposome bupivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Rotator Cuff Tear
Functional Outcomes Following Shoulder Surgery: A Prospective Database
The purpose of this prospective database is to investigate the long-term functional status of patients who have undergone various types of rotator cuff repair surgery.
- Trial name
- NCT00253864
- Testing
- Single row, Double row
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- Ottawa Hospital Research Institute
Scar Prevention, Scar Reduction
A Phase 2a Study to Evaluate the Safety and Efficacy of AZX100 in Trocar Sites of Arthroscopic Shoulder Surgery Patients
The purpose of this study was to determine the safety of AZX100 Drug Product and to determine whether it was effective in preventing or reducing scars that were made from trocars following arthroscopic shoulder surgery.
- Trial name
- NCT00811577
- Testing
- AZX100
- Where
- 5 sites in United States
- Volunteers
- 150 people
- Sponsor
- Capstone Therapeutics
Opioid Use, Unspecified
the Analgesic Duration of Dexmedetomidine Compared to Dexamethasone as Adjuncts to Single Shot Interscalene Block
The purpose of the study is to determine if perineural dexmedetomidine can provide increased prolongation of analgesia when compared to perineural dexamethasone in patients receiving regional block for shoulder surgery.
- Trial name
- NCT02653144
- Testing
- Ropivacaine, Dexmedetomidine, Dexamethasone
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Montefiore Medical Center
Postoperative Complications
Comparative Effectiveness of Peripheral Nerve Blocks for Outpatient Shoulder Surgery
This retrospective, population-based cohort study will evaluate the comparative effectiveness of peripheral nerve blocks on patient outcomes after ambulatory shoulder surgery in adults patients undergoing surgery in Ottawa…
- Trial name
- NCT03309644
- Testing
- Peripheral nerve blockade, No peripheral nerve blockade
- Where
- Canada
- Volunteers
- 1,623 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Shoulder Arthropathy Associated With Other Conditions, Shoulder Arthritis
Microcurrent Dressing to Treat Infections, Before, During and After Surgery
Deep periprosthetic infection following total joint arthroplasty is a major complication. Although it only occurs in a small percentage of patients (~1%), it results in substantial morbidity and a decline in functional outcome.
- Conditions
- Shoulder Arthropathy Associated With Other Conditions, Shoulder Arthritis, Shoulder Osteoarthritis, Shoulder Pain
- Trial name
- NCT03156543
- Testing
- Jumpstart Dressing, Standard Dressing
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Michigan
Post-operative Pain
Initial Local Anesthetic Dose With Continuous Interscalene Analgesia
Objective: To determine a minimally effective initial local anesthetic bolus required to provide satisfactory analgesia using continuous brachial plexus infusion following arthroscopic shoulder surgery using a double-blind…
- Trial name
- NCT00672100
- Testing
- Ropivacaine
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Corewell Health East
Pain
Exparel Interscalene vs Indwelling Catheter
The investigators are comparing an indwelling catheter with intermediate duration local anesthetic to a single shot peripheral nerve block with long acting a local anesthetic (Exparel).
- Trial name
- NCT03827213
- Testing
- Exparel, Indwelling Interscalene Catheter
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Montefiore Medical Center
Shoulder Joint Disease, Complications; Arthroplasty
Tranexamic Acid in Reverse Total Shoulder Arthroplasty
To the Investigators' knowledge, TXA has not been studied in the setting of reverse total shoulder arthroplasty. We propose a double-blinded, randomized, controlled trial comparing perioperative administration of TXA to placebo…
- Conditions
- Shoulder Joint Disease, Complications; Arthroplasty, Intraoperative Complications, Blood Loss, Surgical
- Trial name
- TXA (NCT02043132)
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Corewell Health East
Postoperative Complications
Impact of Anesthesiology Interventions on Postoperative Outcomes in Adult Patients Undergoing Shoulder Surgery
This retrospective, population-based cohort study will evaluate the comparative effectiveness of peripheral nerve blocks on patient outcomes after ambulatory shoulder surgery in adults patients undergoing surgery in Ontario.
- Trial name
- NCT03544775
- Testing
- Isolated General Anesthesia, Peripheral Nerve Block
- Volunteers
- 59,644 people
- Sponsor
- Ottawa Hospital Research Institute
Shoulder Symptoms After Lymph Node Dissection
Pulsed Electromagnetic Fields (PEMF) and Post-Axillary Surgery Morbidity
The most important prognostic indicator for the breast cancer patient is the axillary lymph node status. With the introduction of the sentinel lymph node biopsy, many women were spared the morbidity of a full axillary lymph node…
- Trial name
- NCT01255631
- Testing
- PEMF Device
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Columbia University
Primary Anatomic or Reverse Total Shoulder Arthroplasty
Hydrogen Peroxide to the Wound Following Surgical Incision Affecting Cultures in Primary Shoulder Arthroplast
Cutibacterium acnes has been the focus of much recent shoulder literature, as it has been found to be both a common cause of periprosthetic joint infection as well as a common contaminant in shoulder surgery.
- Trial name
- NCT04609306
- Testing
- H2O2 application to incision
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Florida
Mastectomy, Upper Limb Amputation Below Elbow
Cryoanalgesia to Prevent Acute and Chronic Pain Following Surgery: A Randomized, Double-Masked, Sham-Controlled Study
The ultimate objective of the proposed line of research is to determine if cryoanalgesia is an effective adjunctive treatment for pain in the period immediately following various painful surgical procedures; and, if this…
- Conditions
- Mastectomy, Upper Limb Amputation Below Elbow, Upper Limb Amputation Above Elbow, Lower Limb Amputation Below Knee
- Trial name
- NCT03578237
- Testing
- Cryoneurolysis (active)
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of California, San Diego
Shoulder Surgery, Nerve Block
The Effects of Dexamethasone on Low Dose Interscalene Brachial Plexus Block
A standard interscalene nerve block is performed with long acting local anesthetic (bupivacaine or ropivacaine in concentrations varying from 0.25% to 0.75%).
- Trial name
- ISB-Dex (NCT02322242)
- Testing
- Systemic Dexamethasone, Perineural dexamethasone
- Where
- Canada
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Dr. Stephen Choi
Postoperative Pain
Safety and Efficacy of Tapentadol Immediate Release (IR) and Oxycodone IR for Treatment of Acute Post-op Pain Following Elective Arthroscopic (Surgery Using a Thin Flexible Scope) Shoulder Surgery
The purpose of this study is to evaluate how tapentadol immediate release (IR) and oxycodone IR treat moderate to severe post-operative pain after elective arthroscopic shoulder surgery.
- Trial name
- NCT00814580
- Testing
- Tapentadol IR, Oxycodone IR
- Volunteers
- 382 people
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC