Clinical trials: Sibling
Schizophrenia
Molecular Genetic Study of Schizophrenia: Parent-Offspring Trios
Schizophrenia is a chronic and devastating major psychiatric disorder. Family, twin, and adoption studies indicated that schizophrenia has a significant genetic component.
- Trial name
- NCT00155506
- Volunteers
- 600 people
- Sponsor
- National Taiwan University Hospital
Acute Myeloid Leukemia (AML)
Allogeneic HCT Using Conditioning Regimen of BuFluATG for AML CR1
1. Study Objectives To evaluate the effect of various clinical variables including HLA-disparity and NK cell-related variables, upon outcomes of allogeneic hematopoietic cell transplantation (HCT) using uniform conditioning…
- Trial name
- NCT07155382
- Where
- South Korea
- Volunteers
- 98 people
- Sponsor
- Asan Medical Center
Defibrillators, Implantable, Myocardial Infarction
Risk of Life-threatening Heart Rhythm Disturbances in Siblings
The purpose of this study is to determine if heredity influences the risk of life-threatening heart rhythms (ventricular tachycardia and ventricular fibrillation) after heart attack (myocardial infarction).
- Conditions
- Defibrillators, Implantable, Myocardial Infarction, Tachycardias, Ventricular
- Trial name
- SIBFIB (NCT00498524)
- Testing
- ICD
- Where
- United States
- Volunteers
- 2,047 people
- Sponsor
- Duke University
Behavior, Child, Caries,Dental
Are Dental Neglect and the Siblings Risk Factors in Children
Neglect insidiously affects a child's overall health in all aspects. The aim of this study was to determine whether the presence of siblings caused dental neglect, and whether there was a relationship between dental neglect and…
- Conditions
- Behavior, Child, Caries,Dental, Neglect, Child, Anxiety
- Trial name
- NCT04122508
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Sickle Cell Disease, Thalassemia
Unrelated Hematopoietic Stem Cell Transplantation(HSCT) for Genetic Diseases of Blood Cells
This is a clinical trial of bone marrow transplantation for patients with the diagnosis of a genetic disease of blood cells that do not have an HLA-matched sibling donor.
- Conditions
- Sickle Cell Disease, Thalassemia, Anemia, Granuloma
- Trial name
- NCT00730314
- Testing
- Hematopoietic stem cell transplantation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Children's Hospital Los Angeles
Cystic Fibrosis in Children, Siblings
Internet-delivered Cystic Fibrosis Mental Health Prevention, Wellness, Resource Program: How Does it Work?
The goal of the clinical trial is to test whether a mental health program that is delivered through the Internet works well for children and adolescents with cystic fibrosis (CF) and their healthy siblings.
- Conditions
- Cystic Fibrosis in Children, Siblings, Mental Health, Internet-based Intervention
- Trial name
- iCF-PWR (NCT06020274)
- Testing
- Internet-delivered Cystic Fibrosis Mental Health Prevention, Wellness, and Resource (iCF-PWR) program
- Where
- 2 sites in Canada
- Volunteers
- 120 people
- Sponsor
- University of Regina
Siblings, Childhood Cancer
SibACCESS: Developing a Telehealth Intervention to Address Unmet Psychosocial Needs of Siblings of Children With Cancer
This study aims to address barriers to psychosocial care for siblings of children with cancer by piloting a group-based telehealth program for adolescent siblings of youth with cancer.
- Conditions
- Siblings, Childhood Cancer, Pediatric Cancer, Posttraumatic Stress Disorder
- Trial name
- R03 CA259898 (NCT04889755)
- Testing
- SibACCESS
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Healthy
Effectiveness of the Serious Game 'Broodles' for Siblings of Children With Visual Impairment and/or Intellectual Disability
The support for siblings of children with disabilities is scarce and fragmented, even though studies have shown that these siblings can benefit from support.
- Trial name
- NCT05376007
- Testing
- Serious game 'Broodles'
- Where
- Netherlands
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- VU University of Amsterdam
Cancer
Psychological Interventions in Siblings of Children With Cancer
The purpose of the study is to evaluate the effectiveness of a two-session brief psychological intervention in siblings of pediatric cancer patients with regard to behavior problems and depression.
- Trial name
- NCT00296907
- Testing
- Brief psychological intervention
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University Children's Hospital, Zurich
Sickle Cell Anemia, Sickle Cell-hemoglobin C Disease
Treatment of Sickle Cell Anemia With Stem Cell Transplant
This is a clinical research trial in which a novel preparatory regimen was developed for bone marrow transplant (BMT) which eliminates the primary obstacle to transplant, the lack of a matched sibling donor.
- Conditions
- Sickle Cell Anemia, Sickle Cell-hemoglobin C Disease, Sickle Cell-β0-thalassemia
- Trial name
- NCT01350232
- Testing
- Fludarabine, Cytarabine, Cellular Infusions
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Schizophrenia, Bipolar I Disorder
Emotional Intelligence in Schizophrenia and Bipolar-I- Disorder
Scientific Background Emotional Intelligence (EI) as a part of social cognition is a rather new area of interest which focuses on personality traits and abilities enabling people to cope with both their own feelings as well as…
- Trial name
- NCT01998516
- Where
- Austria
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Disorder Related to Bone Marrow Transplantation, Blood Stem Cell Transplant Failure
Long Term Minor Sibling Donor Well-Being
The goal of this research study is to understand what it is like for a young person to have a sick family member and what it is like to donate bone marrow or stem cells for a sick family member. Primary Aims: 1.
- Conditions
- Disorder Related to Bone Marrow Transplantation, Blood Stem Cell Transplant Failure, Disturbance of Emotions Specific to Childhood and Adolescence, Transmission, Blood, Recipient/Donor
- Trial name
- NCT00667784
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Embryonic Mosaicism, Embryo Culture Media
Media, Morphokinetics, and Mosaicism
Embryonic aneuploidy is the underlying etiology for the majority of failed implantation and miscarriage. Preimplantation genetic screening (PGS) with transfer of a euploid embryo has been advocated as a strategy for increasing…
- Conditions
- Embryonic Mosaicism, Embryo Culture Media, Embryo Morphokinetics, Infertility
- Trial name
- 3M (NCT03503877)
- Testing
- EmbryoScope Plus, GLOBAL MEDIA, SAGE MEDIA
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Inherited Cardiac Conditions
Families' Experiences of Paediatric ICC Diagnosis
This study aims to further understand the experiences of children, their parents and siblings around the time when the child and their family are informed of a diagnosis of an inherited cardiac condition (ICC).
- Trial name
- FEPICCD (NCT02737111)
- Testing
- Initial Screening Process, Information and Informed Consent, Interview
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Survival, Embryo Quality
Oocyte Survival After Vitrification in an Open or Closed Device With Closed Storage.
The survival rate (and embryo quality) of donor oocytes with two commercially available devices.
- Trial name
- NCT01952184
- Testing
- CBSvit HS device, Cryotop SC device
- Where
- Belgium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Assisted Reproductive Technology, Infertility
Sperm Micro-swim up Technique; Process and Select in the Same Dish: a Sibling-oocyte-split Design
A sibling-Oocyte-split design will be conducted on oocytes before denudation and divided into two groups : control group (MII oocytes will be injected using sperm processed by Density gradient method) and sample group ( MII…
- Trial name
- NCT05113225
- Testing
- Micro-swim up technique
- Where
- Egypt
- Volunteers
- 156 people
- Sponsor
- Royal Fertility Center, Egypt
Type 1 Diabetes
Compliance to Vaccination in Children With Diabetes and Their Siblings
This is an observational, single-center, cross-sectional study about adherence to both obligatory and recommended vaccination in children with Type 1 Diabetes Mellitus and their siblings.
- Trial name
- NCT07471906
- Testing
- Compliance to vaccination schedule
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Aristotle University Of Thessaloniki
Autism Spectrum Disorder
Efficacy of IMPACT in Infant Siblings of Children With ASD
Over a 5 year period infant and baby siblings of children with autism spectrum disorders (ASD) will be recruited to this study and will be randomized into 2 groups.
- Trial name
- IMPACT (NCT03274622)
- Testing
- Impact Parent Training, No Impact
- Where
- 2 sites in United States
- Volunteers
- 97 people
- Sponsor
- Vanderbilt University
Breast Cancer, Colorectal Cancer
Identification of Genes Associated With Cancer in Patients and Siblings Who Have Cancer
RATIONALE: Identification of genes that may be associated with developing certain types of cancer may someday provide important information about a person's risk of getting cancer.
- Conditions
- Breast Cancer, Colorectal Cancer, Lung Cancer, Prostate Cancer
- Trial name
- NCT00003329
- Testing
- gene mapping
- Where
- 32 sites in United States
- Volunteers
- 4,000 people
- Sponsor
- Eastern Cooperative Oncology Group
Type1diabetes
Gluten and Amylase Trypsin Inhibitors (ATI) Free Diet
Siblings of those with type 1 diabetes are at an increased risk of developing the disease themselves. Through prior research, the investigators have found that siblings as well as those with type 1 diabetes have a general level…
- Trial name
- NCT03443180
- Testing
- Gluten and Amylase Trypsin Inhibitors (ATI)-free diet
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin