Clinical trials: Sickness Behavior
Schizophrenia
Randomized Controlled Trial (RCT) of a Motivational Decision Support System
In this study we will definitively test the decision support system in a randomized controlled trial (RCT) among smokers with severe mental illness (SMI) psychotic disorders. The Specific Aims of the study are: 1.
- Trial name
- RCTEDSS (NCT02086162)
- Testing
- Web-based motivational decision support system, NCI Education
- Where
- 3 sites in United States
- Volunteers
- 184 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Schizophrenia, Schizoaffective Disorder
Nicotine Replacement Therapy for Smoking Cessation in Schizophrenia
This proposal seeks to evaluate a pilot smoking cessation treatment program that will combine nicotine replacement therapy with or without bupropion sustained-release (SR) with cognitive behavioral therapy for smoking cessation…
- Trial name
- NCT00320723
- Testing
- bupropion, transdermal nicotine patch
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- North Suffolk Mental Health Association
Allergic Contact Dermatitis, Metal Allergy
Environmental Exposure to Heavy Metals, Nanoparticles, and Emergent Contaminants and Risk of Allergic Diseases
The goal of this clinical trial is to collect environmental, bio-humoral, and clinical data derived from patients with allergic contact dermatitis (ACD) and systemic metal allergic syndromes related to the exposure to heavy…
- Conditions
- Allergic Contact Dermatitis, Metal Allergy, Food Allergy, Nickel Sensitivity
- Trial name
- MATRIOSKA (NCT06529913)
- Testing
- Collection of environmental, biological, and clinical data
- Where
- 2 sites in Italy
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Obesity, Type 2 Diabetes
PREMIER: PREvention of Metabolic Illness Through prEcision nutRition
Dietary intake is a major driving force behind the escalating obesity and type 2 diabetes epidemics. Large, high-quality clinical trials have shown that close adherence to healthy dietary recommendations significantly reduce the…
- Conditions
- Obesity, Type 2 Diabetes, Metabolic Syndrome, Diet Habit
- Trial name
- PREMIER (NCT04148482)
- Testing
- Dietary intervention
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Schizophrenia, Schizophreniform Disorder
Electronic Cigarettes in Smokers With Mental Illness
People with mental illness are more likely to smoke and are more severely addicted to nicotine than the general population. As a result, the number of deaths related to tobacco is higher.
- Conditions
- Schizophrenia, Schizophreniform Disorder, Bipolar Disorder
- Trial name
- APUS e-Cigs (NCT02212041)
- Testing
- disposable electronic cigarettes
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- King's College London
Professional Burnout
Return to Work After a Workplace-oriented Intervention for Patients on Sick Leave Due to Burnout
The study aims to evaluate the effect on return to work of a workplace intervention with patients being treated for burnout. The intervention intends to reduce job-person mismatch through patient-supervisor communication.The…
- Trial name
- ADA model (NCT01039168)
- Testing
- Workplace dialogue, Care as usual
- Where
- Sweden
- Volunteers
- 76 people
- Sponsor
- Region Skane
Rheumatoid Arthritis
Experimental Medicine Studies of the Brain in Patients With Rheumatoid Arthritis REALISE
The rationale for this study is to use immune molecule-specific drug treatment to leverage a mechanistic understanding of the brain changes that drive sickness behaviour.
- Trial name
- REALISE (NCT05090124)
- Testing
- Adalimumab
- Where
- 2 sites in United Kingdom
- Volunteers
- 46 people
- Sponsor
- NHS Greater Glasgow and Clyde
Hypoxia, Altitude, Cold Exposure
Effects of Physical Training in Altered Environmental Conditions on Exercise Performance
The main objective of the study is to evaluate the physiological-biochemical effects of physical training under artificially altered climatic conditions (using a hypoxic thermoclimatic chamber) in particular to determine the…
- Conditions
- Hypoxia, Altitude, Cold Exposure, Heat Exposure
- Trial name
- NCT06159374
- Testing
- exercise and environmental conditions
- Where
- Poland
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University School of Physical Education, Krakow, Poland
Stress Disorders, Post-Traumatic
Safety and Efficacy of Cognitive Behavior Therapy for People With Post-traumatic Stress and Cardiovascular Illness
This study will evaluate the safety and efficacy of cognitive behavioral therapy in treating people who are experiencing post-traumatic stress disorder after a heart attack.
- Trial name
- NCT00364910
- Testing
- Cognitive behavioral therapy (CBT), Educational session and treatment as usual
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Icahn School of Medicine at Mount Sinai