Clinical trials: Sigmoid Diseases, active
Colorectal Cancer, Diverticulitis of Sigmoid
Intraoperative Use of Oxygen Saturation Imaging to Assess Intestinal Perfusion
This will be a prospective, observational study of patients undergoing laparoscopic colorectal resection with anastomosis. After anastomosis creation and at the time of routine intraoperative flexible sigmoidoscopy, 4 mucosal…
- Trial name
- NCT07587619
- Testing
- Fujifilm monitoring
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Southern California
Colo-rectal Cancer
EMVI as a Determinant of Metastasis in Colorectal Cancer
Bowel cancer is the fourth most commonly occurring cancer and the second highest cause of cancer deaths in the UK. Despite advances in treatment, over 40% of patients will die within 5 years.
- Trial name
- EVIDENCE (NCT06646341)
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Imperial College London
Orthotopic Neobladder
The Supraspinal Control of Lower Urinary Tract Function in Patients With Orthotopic Sigmoid Neobladder.
Orthotopic sigmoid neobladder surgery is one of the ideal urinary diversion methods after radical cystectomy.In recent years, functional imaging studies have revealed brain regions related to urinary system function, but brain…
- Trial name
- NCT05558111
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Colorectal Cancer, Colorectal Anastomosis
Single-Stapled Technique for Colorectal Anastomosis
The goal of this observational multicenter study is to evaluate the safety and feasibility of a single-stapled technique (SST) for colorectal anastomosis and to explore whether this technique is associated with a reduced rate of…
- Conditions
- Colorectal Cancer, Colorectal Anastomosis, Anastomotic Leakage, Diverticular Disease of Left Side of Colon
- Trial name
- SST (NCT07417358)
- Testing
- Single-stapled colorectal anastomosis, Double-stapled colorectal anastomosis
- Where
- 5 sites in Sweden
- Volunteers
- 500 people
- Sponsor
- Umeå University
Diverticulitis of Sigmoid
Quality of Life in Acute Complicated and Chronic Recurrent Left-sided Diverticulitis
Patients presenting in hospital with symptoms of acute diverticulitis. Acute inflammation of the left-sided colon is confirmed with CT scan or ultrasound in experienced centers and diagnosis is defined according to the…
- Trial name
- DATE (NCT05942833)
- Testing
- Sigmoid resection
- Where
- 4 sites in Austria, Germany
- Volunteers
- 136 people
- Sponsor
- Kepler University Hospital
Colorectal Cancer (CRC), Surgery, Colorectal
Study of Colorectal Anastomosis Failures With First Sigmoid or Left Colonic Artery Preservation With D3 Lymphadenectomy
This study is a randomized, controlled trial comparing the short- and long-term outcomes of left colonic artery or first sigmoid artery preservation for rectal surgery.
- Conditions
- Colorectal Cancer (CRC), Surgery, Colorectal, Oncology
- Trial name
- COLAP-D3 (NCT06938490)
- Testing
- Anterior rectal resection with D3-lymphatic dissection
- Where
- Russia
- Volunteers
- 778 people
- Sponsor
- the BELOOSTROV Clinic of High Technologies
Bladder Cancer, Urinary Diversion
Comparison of Safety and Efficacy of Detaenial Sigmoid Neobladder and Ileal Neobladder
Bladder cancer is a common malignant tumor of the urinary system, radical resection plus urinary diversion is the first choice of treatment for muscle invasive bladder cancer.
- Trial name
- NCT03108196
- Testing
- sigmoid, ileal
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Zhujiang Hospital
Colorectal Anastomosis, Left-sided Colon Resection
Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections
The purpose of this study is to evaluate the safety and performance of the Signia™ power handle, Signia™ circular adapter, and Signia™ Tri-Staple™ 2.0 circular reloads (hereafter referred to as Signia™ circular stapler) in…
- Conditions
- Colorectal Anastomosis, Left-sided Colon Resection, Anastomotic Leak, Anastomotic Complication
- Trial name
- SECURE (NCT07351071)
- Testing
- Signia™ circular stapler with Tri-Staple™ Technology (Signia™ Circular Stapling system)
- Where
- 10 sites in United States
- Volunteers
- 137 people
- Sponsor
- Medtronic - MITG
Diverticulitis, Diverticulitis of Sigmoid
Clinical Trial With MBK-01, Intestinal Microbiota Capsules, for the Treatment of Patients With Recurrent Diverticulitis
Patients with diverticulitis experience a prolonged course of the disease and report a variety of physical, psychological and social symptoms, which highly impacts in their quality of life.
- Trial name
- NCT06687382
- Testing
- MBK-01
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- Mikrobiomik Healthcare Company S.L.
Rectal Diseases, Sigmoid Colon Disease, Rectal Cancer, Sigmoid Colon Cancer
Extra-Peritoneal Tunneling Versus Conventional Drain Fixation After Anterior or Low Anterior Resection
The goal of this clinical trial is to learn whether the extra-peritoneal tunneling (EPT) drain fixation method works better and more safely than the conventional drain insertion method after rectal cancer surgery.
- Trial name
- ExPeTuD (NCT07241143)
- Testing
- EPT drain fixation, Conventional drain insertion
- Where
- South Korea
- Volunteers
- 596 people
- Sponsor
- Yeungnam University Hospital
Locally Advanced Pelvic Cancer That Require Pelvic Exenteration
Laparoscopic Robot-assisted Pelvic Exenteration for Pelvic Primary and Recurrent Cancers
The Radium Hospital Oslo University Hospital Estimated date of first patient enrolled: 3rd quarter 2021 Anticipated recruitment period: 4 years Estimated date of last patient completed: 4th quarter 2025 Locally advanced pelvic…
- Trial name
- NCT05186493
- Testing
- robot-assisted total pelvic exenteration
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Bladder Cancer
Comparison Capsule Sparing Cystectomy and Radical Cystoprostatectomy in Men With Bladder Cancer
Bladder cancer is a common malignant tumor of the urinary system, radical resection plus urinary diversion is the first choice of treatment for muscle invasive bladder cancer.
- Trial name
- NCT05067101
- Testing
- Capsule Sparing Cystectomy (CSC), Conventional Radical Cystoprostatectomy (CRC)
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Zhujiang Hospital
Rectal Cancer, Sigmoid Cancer
Adaptive Anastomosis for Anterior Resection in Sigmoid and Proximal Rectal Cancer or Premalignant Lesions
Background: Anastomotic leakage (AL) after colorectal surgery remains a significant challenge, associated with increased morbidity, mortality, poor oncological outcomes, and reduced quality of life.
- Conditions
- Rectal Cancer, Sigmoid Cancer, Premalignant Lesion, Colorectal Cancer
- Trial name
- ADAPT (NCT07056374)
- Testing
- C-REX RectoAid Cath
- Where
- Netherlands
- Volunteers
- 165 people
- Sponsor
- Amsterdam UMC, location VUmc
Colorectal Neoplasms, Fluorescence
Fluorescence Laparoscopic Navigation for Rectal Cancer and Sigmoid Colon Cancer
To explore the short-term and long-term outcomes of fluorescence laparoscopic navigation D2 lymph node dissection for colorectal cancer surgery by comparing it with D3 lymph node dissection.
- Conditions
- Colorectal Neoplasms, Fluorescence, Lymph Node Excision
- Trial name
- FLORA-01 (NCT05730595)
- Testing
- lymph node dissection
- Where
- 19 sites in China
- Volunteers
- 550 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Pulsatile Tinnitus
VivaStent Feasibility Study
Subjects are enrolled in the study following signature of the Informed Consent Form and confirmation of eligibility criteria. During the screening/baseline phase, demographic and clinical data, medical history, concomitant…
- Trial name
- NCT07515781
- Testing
- cerebral venous stenting
- Where
- France
- Volunteers
- 15 people
- Sponsor
- V-Flow 21
Sigmoid Cancer
A Prospective, Randomized, Open, Parallel-controlled, Superior-efficacy Clinical Study of Radical Sigmoidectomy for Sigmoid Cancer Versus Radical Sigmoidectomy Combined with Indocyanine Green Fluorescence Imaging Lymphatic Tracing Dissection in the Treatment of Sigmoid Cancer
he purpose of this study is to explore the clinical outcomes of Indocyanine Green Tracer using in laparoscopic radical sigmoidectomy for sigmoid adenocarcinoma (cT2-T4a N0 M0，T1-T4a N+ M0).
- Trial name
- NCT06396806
- Testing
- indocyanine green fluorescence imaging lymphatic tracing
- Where
- China
- Volunteers
- 1,072 people
- Sponsor
- Sun Yat-sen University
Cancer, Colorectal Neoplasms
Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers
Patients with suspected or proven sigmoid colon adenocarcinoma, eligible for curative treatment whose MRI can be reviewed prior to surgery and has no decision regarding radical treatment are eligible.
- Conditions
- Cancer, Colorectal Neoplasms, Colon, Sigmoid, Magnetic Resonance Imaging
- Trial name
- IMPRESS (NCT02222844)
- Testing
- Preoperative MRI scan
- Where
- 16 sites in United Kingdom
- Volunteers
- 244 people
- Sponsor
- Imperial College London
Diverticulum, Colon, Sigmoid
LASER Trial. LAparoscopic Elective Sigmoid Resection Following divERticulitis - a Multicenter, Prospective, Randomized Clinical Trial
The purpose of this study is to find out whether elective sigmoid resection will improve quality of life compared to conservative treatment with lifestyle guidance and fiber supplement in patients with a recurrent or complicated…
- Trial name
- LASER (NCT02174926)
- Testing
- Elective laparoscopic sigmoid resection, Conservative treatment
- Where
- 11 sites in Finland
- Volunteers
- 133 people
- Sponsor
- Helsinki University Central Hospital
Cholecystitis, Cholecystitis, Chronic
Shortwave Infrared Surgical Imaging Device Study
The goal of this observational study is to perform an in-human assessment of an investigational shortwave infrared (SWIR) imaging device, aimed to enhance the visualization of critical anatomical structures during surgical…
- Conditions
- Cholecystitis, Cholecystitis, Chronic, Chronic Calculous Cholecystitis, Primary Hyperparathyroidism
- Trial name
- NCT07744425
- Testing
- Observational study of SWIR imaging device in surgery
- Where
- 6 sites in United States
- Volunteers
- 50 people
- Sponsor
- Cision Vision, Inc.