Clinical trials: Skilled Nursing Facility Patients
Alzheimer Disease
Optimizing Care for Patients With Dementia
Of the 1.4 million nursing home (NH) residents in long term care facilities, more than half have Alzheimer's disease or dementia.
- Trial name
- NCT03442322
- Testing
- transdisciplinary approach, multidisciplinary approach
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of Pittsburgh
Transitional Care, Caregivers
Connect-Home Clinical Trial
This study will test whether transitional care targeting care needs of seriously ill, skilled nursing facility (SNF) patients and their caregivers will help to improve SNF patient outcomes (preparedness for discharge, quality of…
- Conditions
- Transitional Care, Caregivers, Patient Discharge, Aging
- Trial name
- NCT03810534
- Testing
- Connect-Home
- Where
- United States
- Volunteers
- 654 people
- Sponsor
- University of North Carolina, Chapel Hill
Diabetes
ADA Linagliptin in Long Term Care
This is a study to determine whether glycemic control, as measured by change in HbA1c and frequency of hypoglycemia, is different between treatment with linagliptin (Tradjenta®) and basal insulin in long term care residents(LTC)…
- Trial name
- NCT02061969
- Testing
- linagliptin, insulin glargine
- Where
- 4 sites in United States
- Volunteers
- 140 people
- Sponsor
- Emory University
Osteoporosis, Postmenopausal, Osteoporosis
Preventing Osteoporosis Using Denosumab
The purpose of this research study is to find out if denosumab (Prolia®), an injection given in the arm under the skin every 6 months, works to treat bone loss and prevent it from worsening in older men and women (ages 65 and…
- Conditions
- Osteoporosis, Postmenopausal, Osteoporosis, Osteoporotic Fractures
- Trial name
- PROUD (NCT02753283)
- Testing
- denosumab, Calcium and Vitamin D
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Susan L. Greenspan
Alzheimer Disease, Dementia
Aligning Patient Preferences: a Role Offering Alzheimer's Patients, Caregivers, and Healthcare Providers Education and Support
Nursing home (NH) patients with Alzheimer's disease and related dementias often receive unwanted, burdensome treatments such as hospitalization.
- Trial name
- APPROACHES (NCT03323502)
- Testing
- APPROACHES ACP Specialist Program, Standard of care
- Where
- 2 sites in United States
- Volunteers
- 47,396 people
- Sponsor
- Indiana University
Atrial Fibrillation, Deep Vein Thrombosis
Weekly Monitoring Strategy of Capillary INR Versus Monthly Monitoring Strategy of Venous INR in Elderly Patients in a Nursing Home.
This primary care study aims to compare the "time in therapeutic range" (TTR) of two strategies for monitoring the international normalized ratio (INR) over 6 months in nursing homes.
- Conditions
- Atrial Fibrillation, Deep Vein Thrombosis, Stroke
- Trial name
- INR-CAP (NCT05561244)
- Testing
- Weekly monitoring using the capillary International Normalised Ratio strategy
- Where
- 33 sites in France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Poor Quality Sleep
Efficacy & Safety of Eszopiclone (Lunesta) in Nursing Home Patients
The purpose of this study is to examine the effects of the sleep aid Lunesta (Eszopiclone), on older adults who reside in a nursing home and have poor sleep as determined by wrist actigraphy.
- Trial name
- NCT00460993
- Testing
- Lunesta
- Volunteers
- 71 people
- Sponsor
- Emory University
Geriatric Assessment, Frail Elderly
Drug Reduction in Older Patients: The DROP Trial
Project Objectives: The proposed randomized, controlled trial will evaluate the effects of procedures to reduce medications among hospitalized older Veterans discharged to nursing homes using an hybrid study design to inform…
- Conditions
- Geriatric Assessment, Frail Elderly, Skilled Nursing Facilities, Patient-centered Care
- Trial name
- DROP (NCT03722017)
- Testing
- Deprescribing intervention
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- VA Office of Research and Development
Polypharmacy, Care Transitions
A Randomized Controlled Trial to Deprescribe for Older Patients With Polypharmacy
This randomized, controlled trial will evaluate the effects of an intervention to reduce exposure to medications among hospitalized older adults discharged to skilled nursing facilities (SNFs).
- Conditions
- Polypharmacy, Care Transitions, Geriatric Syndromes
- Trial name
- Shed-Meds (NCT02979353)
- Testing
- Shed-Meds: A Patient-Centered Deprescribing Intervention
- Where
- United States
- Volunteers
- 372 people
- Sponsor
- Vanderbilt University Medical Center
Osteoporosis, Bone Loss
Zoledronic Acid for Osteoporosis in the Elderly
This trial will examine the safety, efficacy and feasibility of a single dose of intravenous zoledronic acid in the maintenance of skeletal integrity for frail, institutionalized women, who are most at risk for the deleterious…
- Conditions
- Osteoporosis, Bone Loss, Fragility Fractures
- Trial name
- ZEST (NCT00558012)
- Testing
- Intravenous zoledronic acid, Vitamin D 800 IU/daily, Calcium 1200 mg/daily
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- University of Pittsburgh
Pseudobulbar Affect (Involuntary Laughing and/or Crying)
Effectiveness, Safety, and Health-Related Outcomes of NUEDEXTA® in Nursing Home Patients With Pseudobulbar Affect (PBA)
6 month study of NUEDEXTA ® (Dextromethorphan Hydrobromide and Quinidine Sulfate) for the treatment of Pseudobulbar Affect (PBA) in Nursing Home Patients.
- Trial name
- NCT02496039
- Testing
- NUEDEXTA®
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Avanir Pharmaceuticals
Osteoporotic Fractures, Osteoporosis, Postmenopausal
Zoledronic Acid for Osteoporotic Fracture Prevention (ZEST II)
The goal of this study is to perform the first fracture reduction clinical trial with a potent antiresorptive agent (intravenous zoledronic acid) in the most vulnerable long-term care population.
- Trial name
- ZEST II (NCT02589600)
- Testing
- Zoledronic acid, vitamin D, calcium
- Where
- United States
- Volunteers
- 310 people
- Sponsor
- Susan L. Greenspan