Clinical trials: Skin Appearance
Cellulite
Treatment for Improvement of Cellulite Appearance Using Form Applicator
Open-label, non-randomized, prospective, multi-center, self-controlled clinical study with masked evaluation.
- Trial name
- NCT05882721
- Testing
- Sofwave
- Where
- 5 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sofwave Medical LTD
Actinic Keratoses
Evaluating Skin Appearance Following 5-Flourouracil Cream for Treatment of Actinic Keratosis and the Effects of Topical Agents
This proposed project will be an open-label, split face, randomized controlled pilot study. Up to 60 patients with diffuse facial actinic keratosis will be enrolled in the study.
- Trial name
- NCT03279328
- Testing
- Topical Steroid Ointment, Vaseline, Skin Barrier Moisturier
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Arizona
Fruit and Vegetable Consumption
You Are What You Eat: A Randomised Controlled Trial of an Appearance-based Dietary Intervention
This study investigated whether illustration of the facial appearance benefits of fruit and vegetable consumption is able to motivate increased intake of this food group.
- Trial name
- NCT01511484
- Testing
- Information-only, Generic appearance intervention, Personalised appearance intervention
- Where
- United Kingdom
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Perception Lab
Basal Cell Carcinoma, Squamous Cell Carcinoma
Eversion in Dermatologic Surgery: Is Cosmetic Appearance Improved?
The investigators hypothesize that everting wound edges while suturing surgical sites will result in more aesthetic scars. Additionally, we also hypothesize that small to moderate wound irregularities present at 3 months will…
- Conditions
- Basal Cell Carcinoma, Squamous Cell Carcinoma, Melanoma
- Trial name
- NCT01770002
- Testing
- Everted suture technique, Non-everted suture technique
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Skin Graft
Pelashield vs Xeroform
The purpose of this research study is to compare the effects (good or bad) of a new skin graft dressing (PelashieldTM) compared to the one traditionally used (Xeroform).
- Trial name
- NCT07734519
- Testing
- Pelashield, Xeroform
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Wake Forest University Health Sciences
Skin Aging, Weight Loss
Effect of Revival Soy on Weight Loss and Skin, Hair, and Nails in Premenopausal Women
The purpose of this study is to determine if dietary consumption of Revival Soy can improve the appearance of the skin, hair, and finger nails and support weight loss in overweight, premenopausal women.
- Trial name
- NCT00352157
- Testing
- Revival Soy Dietary Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Physicians Pharmaceuticals, Inc.
Breast Cancer, Breast Neoplasms
Augmented-Reality ICG Fluorescence Second-Look for Residual Nodal Disease After Axillary Dissection in Breast Cancer
This study tests whether special imaging goggles can help surgeons find lymph nodes that may be left behind during breast cancer surgery.
- Conditions
- Breast Cancer, Breast Neoplasms, Sentinel Lymph Node, Lymphatic Metastasis
- Trial name
- AR4SLN (NCT07696754)
- Testing
- Augmented-reality ICG fluorescence second-look imaging
- Where
- North Macedonia
- Volunteers
- 30 people
- Sponsor
- Ss. Cyril and Methodius University of Skopje
Reduction in Hypertrophic Skin Scarring
Safety and Efficacy Study of EXC 001 to Improve the Appearance of Scars From Prior Breast Surgery
The study will investigate the efficacy of various doses and regimens of EXC 001 in reducing skin scarring in subjects undergoing revision of scars from prior surgery.
- Trial name
- NCT01346969
- Testing
- EXC 001
- Where
- 12 sites in United States
- Volunteers
- 68 people
- Sponsor
- Pfizer
Rosacea
An Evaluation of the Cosmetic Appearance of Metronidazole Gel (MetroGel®) 1%
The purpose of this study is to determine the cosmetic appearance of metronidazole gel (MetroGel®) 1% with commonly marketed facial foundations.
- Trial name
- NCT00668655
- Testing
- Metronidazole Gel
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Galderma R&D
Nevi
Study to Test Genetic Alterations Among Different Dermoscopic Types of Melanocytic Nevi.
This project is a multicenter study in which we will investigate a dual concept of nevogenesis. Study location is the Department of Dermatology at the Medical University of Graz in collaboration with centers in Austria (Vienna)…
- Trial name
- NCT00422448
- Testing
- To test the frequency of BRAF and NRAS mutations among nevi
- Where
- Austria
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Keloid, Wound Heal
Comparing the Effect of siSPARC Microneedle Patch Versus siSPARC+siLR4A Microneedle Patch on Post-surgical Scars
This randomized, double-blind controlled study aims to compare the effect on appearance of post- surgical scars between daily application of siSPARC microneedle patch versus siSPARC + siLR4A microneedle patches.
- Conditions
- Keloid, Wound Heal, Wound
- Trial name
- NCT06138964
- Testing
- siSPARC + siLR4A microneedle patches, siSPARC microneedle patch
- Where
- Singapore
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Skin Centre
Cellulite
A Study to Assess the Adverse Events and Effectiveness of Rapid Acoustic Pulse (RAP) Device for the Appearance of Cellulite in Adult Participants
Cellulite is the rippling or dimpling of the skin most commonly located on the thighs and buttocks of women. Its appearance and texture are often likened to that of "cottage cheese" or an orange peel.
- Trial name
- NCT05664581
- Testing
- Rapid Acoustic Pulse
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Zeltiq Aesthetics
Oily Skin
Topical Acetyl Hexapeptide-8 and the Cosmetic Appearance of Oily Skin
This is a randomized double-blinded study examining the effect of topical Acetyl Hexapeptide-8 AH8) for improving the cosmetic appearance and experience of oily skin.
- Trial name
- NCT02597777
- Testing
- Acetyl Hexapeptide-8
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Skin Aging
Proof of Concept Anti-ageing Clinical Study in Healthy Subjects
The objective of this POC clinical study is to evaluate the moisturising effects on fine lines and wrinkles, texture, barrier function, hydration and elasticity delivered by 4 weeks of twice daily application of the test product…
- Trial name
- NCT03180645
- Testing
- Test product (Moisturising cream), Positive control (Commercial market place moisturising cream), No treatment
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Obstructive Sleep Apnea
The Treatment of Obstructive Sleep Apnea With Continuous Positive Airway Pressure on Appearance and Age
The investigators hypothesized that the treatment of obstructive sleep apnea (OSA) with continuous positive airway pressure (CPAP) will positively affect the appearance of the patient.
- Trial name
- NCT02117271
- Testing
- continuous positive airway pressure, Breathe Right ®
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Nucleo Interdisciplinar da Ciencia do Sono
Skin Laxity
Evaluation of the Evoke Radiofrequency Device for Improvement of Skin Appearance
Evaluation of the Evoke Radiofrequency Device for Improvement of Skin Appearance
- Trial name
- NCT04721600
- Testing
- Evoke Radiofrequency Device
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- InMode MD Ltd.
Keloids, Hypertrophic Scars
Effect of Transparent, Self-drying Silicone Gel on the Treatment of Hypertrophic Abdominal Scars
Keloids and hypertrophic scars are a common subject of dermatologic consultations. Therapeutic management of such conditions remains challenging because of their high rate of recurrence and lack of curative treatment.
- Trial name
- NCT01078428
- Testing
- Topical silicone gel, Vaseline
- Where
- Thailand
- Volunteers
- 38 people
- Sponsor
- Mahidol University
Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8
Enhancing Skin Appearance and Quality of Life in Breast Cancer Survivors on Aromatase Inhibitor Therapy
This study evaluates changes in skin quality and self-esteem among breast cancer patients who are initiating aromatase inhibitor therapy.
- Conditions
- Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8
- Trial name
- NCT06401889
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Mayo Clinic
Cosmetic Effect
Proof of Concept Study to Isolate Cosmetic Improvement of Skin Using the Vitro Biopharma Secretome/Exosome Serum
The purpose of this research is to characterize the safety, tolerability and efficacy of the investigational topical cosmetic product, the Vitro Biopharma Exosome Serum (Intervention), in impacting the cosmetic appearance of skin…
- Trial name
- NCT07620158
- Testing
- Secretome/Exosome Serum
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Vitro Biopharma Inc.
Diabetic Foot Ulcers
A Study to Look at the Effects of Four Weeks of Treatment on the Healing of Diabetic Foot Ulcers
The purpose of this study is to assess the effect of four weeks of treatment with Santyl Ointment, compared to White Petrolatum, on the change from baseline in wound area of diabetic foot ulcers over four weeks, and on the…
- Trial name
- NCT01143714
- Testing
- Santyl, White Petrolatum
- Where
- 6 sites in United States
- Volunteers
- 57 people
- Sponsor
- Healthpoint