Clinical trials: Skin Atrophy
Duchenne / Becker Muscular Dystrophy, Osteogenesis Imperfecta (OI)
Social Cognition in Dystrophinopathies and Neurodevelopmental Disorders
The primary aim of this observational study is to investigate specific aspects of social cognition in dystrophinopathies. Body awareness, interpersonal distance and emotional processing will be measured in a sample of patients…
- Conditions
- Duchenne / Becker Muscular Dystrophy, Osteogenesis Imperfecta (OI), Social Cognition
- Trial name
- NCT06874166
- Testing
- Electroencephalography (EEG), Social Cognition Tasks
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Muscle Atrophy, Muscle Weakness
Neuromodulation for Prevention of Intensive Care Unit Acquired Weakness and Post Intensive Care Syndrome
Post-intensive care syndrome (PICS) encompasses persistent physical, cognitive, and psychiatric symptoms following ICU discharge, commonly triggered by serious conditions such as respiratory failure, sepsis, and mechanical…
- Conditions
- Muscle Atrophy, Muscle Weakness, Blood Flow
- Trial name
- NCT06238609
- Testing
- Intervention Group, Control Group
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Bijan Najafi, PhD
Healthy, Muscular Dystrophy
Studies of Patients With Skin Disease, Patients With Neurological Degenerations, and Normal Volunteers
It is proposed that patients with skin disease due to presumed immunologic, genetic or viral-induced abnormalities, patients with neurological degenerations, and normal controls be evaluated with various in vitro studies of…
- Conditions
- Healthy, Muscular Dystrophy, Retinal Degeneration, Skin Diseases
- Trial name
- NCT00001164
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Skin and Connective Tissue Diseases
A Single-Centre Clinical Trial to Assess Steroid Induced Skin Atrophy on Healthy Skin
The purpose of this study is to assess steroid induced skin atrophy by sonography.
- Trial name
- NCT02355639
- Testing
- Clobetasol propionate 0.05 % ointment, Betamethasone dipropionate 0.064 % ointment, Petrolatum ointment
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- LEO Pharma
Acne Vulgaris, Atrophic Acne Scar
Autologous Plasma Gel Injection Versus Polydioxanone Cog Threads Insertion for the Treatment of Atrophic Post-acne Scars: a Split-face
Both male and female patients, with atrophic acne scars All patients underwent one session of subcision before receiving: A: cog PDO threads on one side of the face (one session). B: plasma gel on the other side (one session).
- Trial name
- NCT06580691
- Testing
- Subcision plus Plasma gel injection Vs Subcision plus Cog PDO threads
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sameh Sarsik
Androgenetic Alopecia
Association of Polymorphisms in the Androgen Receptor Gene and Finasteride Response in Women With Androgenetic Alopecia
Previous studies of finasteride treatment in women with hair loss have failed to show positive results, yet, some women have responded anecdotally.
- Trial name
- NCT01052870
- Testing
- Finasteride
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- HairDx, LLC
Acne Vulgaris
Fractional CO2 Laser Delivery of Topical Insulin Versus Platelet Rich Plasma in Treatment of Atrophic Post Acne Scars
compare the efficacy and safety of treating atrophic post acne scars with topical insulin versus Platelet rich Plasma PRP combined with fractional ablative Co2 laser
- Trial name
- NCT06590909
- Testing
- Fractional CO2 laser assisted PDT
- Volunteers
- 22 people
- Sponsor
- Assiut University
Atrophic Acne Scar
Use of Artefill® for Moderate to Severe Atrophic Acne Scar Correction
The purpose of this study is to determine whether Artefill is safe and effective for the correction of atrophic facial acne scars.
- Trial name
- NCT01559922
- Testing
- Normal Saline, Artefill
- Where
- 10 sites in United States
- Volunteers
- 175 people
- Sponsor
- Suneva Medical, Inc.
Breast Cancer, Frailty
Multicomponent Prehabilitation in Older Adults With Breast Cancer
Older adults with breast cancer frequently present with frailty, decreased functional reserve, and increased risk of postoperative complications.
- Conditions
- Breast Cancer, Frailty, Sarcopenia, Aging
- Trial name
- PREHAB-BC65 (NCT07531836)
- Testing
- Home-based Multicomponent Prehabilitation (Vivifrail), Supervised Multicomponent Prehabilitation, Comprehensive Geriatric Assessment and Optimization
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Fundacion Miguel Servet
Striae; Atrophy
MICRONEEDLING ON CLINICAL PARAMETERS OF STRIAE ALBA AND MORPHOLOGICAL PARAMETERS OF THE FEMALE TEGUMENTARY SYSTEM
Stretch marks are dermal scars of multifactorial etiology, for which several treatments have been proposed. Among these is microneedling (MN), a technique that stimulates collagen production.
- Trial name
- NCT06636799
- Testing
- Microneedling only, Microneedling and actives
- Where
- Brazil
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Isabel de Almeida Paz
Breast Cancer
Bicalutamide Plus Aromatase Inhibitors in ER(+)/AR(+)/HER2(-) Metastatic Breast Cancer
This study is aim to evaluate the efficacy and safety of bicalutamide and aromatase inhibitor in ER(+)/AR(+)/HER2(-) metastatic breast cancer patients who have disease progression after treatment of an aromatase inhibitor.
- Trial name
- BETTER (NCT02910050)
- Testing
- Bicalutamide, Aromatase Inhibitor
- Where
- China
- Volunteers
- 58 people
- Sponsor
- Xu fei
Healthy Volunteer, Rheumatoid Arthritis
Phenomics in Autoimmune and Inflammatory Diseases
The family of inflammatory/autoimmune systemic diseases (IAD) form a continuum from pure inflammatory diseases to pure autoimmune diseases, encompassing a large panel of inflammatory diseases with some autoimmune components, and…
- Conditions
- Healthy Volunteer, Rheumatoid Arthritis, Ankylosing Spondylitis, Systemic Lupus Erythematosus/Antiphospholipid Syndrome
- Trial name
- TRANSIMMUNOM (NCT02466217)
- Testing
- 1: AID groups, 2: Control groups
- Where
- 2 sites in France
- Volunteers
- 537 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lipodystrophy Syndrome, HIV, Sarcopenia
Detraining in People Living With HIV/AIDS
The goal of this study was to evaluate the effect of detraining in the components of physical aptitude of people living with HIV/Aids (PVHA).
- Trial name
- PVHA (NCT03075332)
- Testing
- combined training
- Where
- 2 sites in Brazil
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Post-Acne Atrophic Scars, Carbon Dioxide Lasers
PRP Plus Fractional CO₂ Laser for Acne Scars
This randomized controlled trial aims to evaluate whether adding platelet-rich plasma (PRP) to fractional CO₂ laser resurfacing improves the treatment of moderate-to-severe acne scars compared with laser alone.
- Conditions
- Post-Acne Atrophic Scars, Carbon Dioxide Lasers, Platelet-Rich Plasma
- Trial name
- PRPLT (NCT07352215)
- Testing
- Fractional CO₂ Laser + Platelet-Rich Plasma (PRP), Fractional CO₂ Laser Only
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Gujranwala medical college District Headquarters Hospital, Gujranwala
Sarcopenia
Presence and Comparison of Sarcopenia in Early Rheumatoid Arthritis and Rheumatoid Arthritis
introduction: In this study, the presence of sarcopenia in cases with early rheumatoid arthritis and established rheumatoid arthritis will be compared.
- Trial name
- NCT06284200
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Kayseri City Hospital
Breast Cancer Female
Lactobacillus Vaginalis Capsules for Treatment of Vulvovaginal Atrophy in Young Breast Cancer Patients
This study is a prospective, randomized controlled, phase II clinical study with a planned enrolment of 60 patients. The study focuses on the efficacy and safety of Lactobacillus vaginalis capsules for the prevention and/or…
- Trial name
- NCT05974449
- Testing
- Vaginal Lactobacillus capsules
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Atrophic Acne Scars
Treatment of Atrophic Acne Scars With Platelet-Rich Plasma and Skin Needling
Investigators will collect blood specimens from the participating patients and then blood samples will be centrifuged in order to collect platelet-rich plasma which is going to be injected in the atrophic acne scars.
- Trial name
- NCT02798016
- Testing
- Platelet-Rich Plasma, Micro-needling
- Where
- Syria
- Volunteers
- 50 people
- Sponsor
- Damascus University
Atrophic, Scars
Efficacy of Saline Injection Therapy in Atrophic Acne Scars
The purpose of the study was to determine the efficacy of saline injection in post-acne atrophic scars on face. All patients with mild, moderate \& severe post-acne atrophic scars, above age of 15 years without any co-morbid…
- Trial name
- NCT04197245
- Testing
- saline injection therapy in post-acne atrophic scars
- Where
- Pakistan
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Jinnah Postgraduate Medical Centre
Dyspareunia
Fractional CO2 Laser Therapy Versus 4% Topical Lidocaine Gel for Dyspareunia in Breast Cancer Survivors
This trial seeks to determine if therapy with a CO2 laser to the vagina is more effective than lidocaine to the opening of the vagina before intercourse to reduce painful intercourse in women who are breast cancer survivors.
- Trial name
- BCLS (NCT03257670)
- Testing
- 4% Topical Lidocaine Gel, CO2RE fractional laser therapy
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Dermatomyositis, Glycogen Storage Disease Type II
Genetic and Family Studies of Inherited Muscle Diseases
The purposes of this study are to identify gene mutations in patients with the muscle diseases phosphofructokinase (PFK) deficiency, acid maltase deficiency (GAA deficiency) and to learn more about how these diseases develop.
- Conditions
- Dermatomyositis, Glycogen Storage Disease Type II, Glycogen Storage Disease Type VII, Myositis
- Trial name
- NCT00001331
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)