Clinical trials: Skin Burn
Grafting, Skin, Burn
Fixation of Skin Grafts in Patients With Burns: Comparison Between Cyanoacrylate Glue and Skin Staples
Skin graft fixation is essential for the success of its survival. There are several common methods for skin graft fixation including sutures, skin staples and glue.
- Trial name
- NCT00363558
- Where
- Israel
- Volunteers
- 44 people
- Sponsor
- Rabin Medical Center
Burns, Skin Graft Complications
Suprathel Versus Xeroform for the Management of Skin Graft Donor Sites
The investigators aim to study whether Suprathel, a synthetic temporary skin substitute developed by PolyMedics Innovations GmBH aids in the management of patient pain and wound healing when compared to the current standard…
- Conditions
- Burns, Skin Graft Complications, Skin; Deformity
- Trial name
- Suprathel (NCT04014400)
- Testing
- Suprathel or Xeroform donor site application
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Burn Scar, Scar
CO2 Laser Revision for Burn Related Donor Site Scars
Scarring from burn wounds remains a chronic and often severe sequela of burn injury. Burn wounds may be left to heal by secondary intention or treated with surgical skin grafting; in both circumstances, significant scars likely…
- Conditions
- Burn Scar, Scar, Skin Graft Scar
- Trial name
- NCT04456127
- Testing
- Fractional CO2 Laser
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medstar Health Research Institute
Wound of Skin, Burns
Pilot Study: KeraStat® Gel for Topical Delivery of Morphine for Management of Non-Healing, Painful Open Wounds and Ulcers
This study is intended to provide information from subjects who currently have painful, chronically open wounds and assess the pain reduction capacity of KeraStat® Gel with Morphine.
- Trial name
- NCT05217160
- Testing
- KeraStat® Gel with Morphine application, KeraStat® Gel application
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- The Metis Foundation
Wounds
Efficacy Study of GLYC-101 to Evaluate Outcomes After Post-laser Ablation
Study is intended to evaluate safety and efficacy parameters in patients treated with GLYC-101 gel or placebo after laser ablation.
- Trial name
- NCT00656474
- Testing
- GLYC-101 gel (1.0 %)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- TR Therapeutics
Complicated Skin and Soft Tissue Infection
Evaluation of Ceftaroline Fosamil Versus Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections
The purpose of this study is to evaluate the effects of Ceftaroline Fosamil versus Vancomycin plus Aztreonam in treatment of patients with complicated bacterial skin and soft tissue infections.
- Trial name
- NCT01499277
- Testing
- Ceftaroline fosamil, Vancomycin, Aztreonam
- Where
- 91 sites in United States, Argentina and 26 more
- Volunteers
- 802 people
- Sponsor
- Pfizer
Burns
Microcurrent for Healing Autogenous Skin Donor Sites
This single-center, prospective, randomized, and controlled study evaluated the efficacy of silver-coated dressing with active microcurrent in comparison to silver-coated dressing with sham microcurrent on wound-closure time for…
- Trial name
- NCT00558701
- Testing
- Microcurrent stimulator, Silverlon Wound Contact Dressing
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- United States Army Institute of Surgical Research
Thermal Injury, Skin Burn
Gellan Contact Study
The primary objective of this study will be to establish the safety of the two different Gellan formulations (sheet and fluid gel) following its application to the epidermis of healthy volunteers.
- Trial name
- GCS (NCT04044014)
- Testing
- Gellan sheet, Gellan fluid gel, Mepitel One
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Third Degree Burns
Comparing Modified Meek and Mesh Techniques
This is a clinical trial study that compare two plastic surgery techniques in patients with third degree of burning and both techniques are used in all patients but in different areas of burning sites of the patients.
- Trial name
- NCT02285517
- Testing
- modified Meek skin grafting technique, mesh skin grafting technique
- Volunteers
- 20 people
- Sponsor
- Shahraki, Babak N., M.D.
Pain, Postoperative, Burns
Liposomal Bupivacaine Versus Lidocaine for Skin Graft Donor Site Pain
Donor site pain study comparing post-operative donor site pain and opioid consumption after use of Lidocaine, Liposomal Bupivicaine or regional nerve block for split thickness skin graft harvesting in patients with less than 20%…
- Trial name
- NCT03854344
- Testing
- Lidocaine Hydrochloride, Liposomal bupivacaine, Bupivacaine Hydrochloride
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Kansas Medical Center
Burns
Evaluation of Dermafill Dressing for Donor Sites
The purpose of the study is to compare one type of dressing against the current standard dressing that is used to cover the unburned area of the skin where a piece of skin is removed to cover another part of the body that was…
- Trial name
- NCT00137163
- Testing
- Dermafill Dressing
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- United States Army Institute of Surgical Research
Burn Wound, Pressure Ulcers Stage II
Study to Evaluate the Performance and Safety of the Medical Device Argogen
A wound, i.e., a break in the skin, can result from several reasons. Pressure ulcers (also called pressure sores, bed sores and decubitus ulcers) are localized damage to the skin and underlying soft tissue usually over a bony…
- Conditions
- Burn Wound, Pressure Ulcers Stage II, Pressure Ulcers Stage III
- Trial name
- NCT05649332
- Testing
- Argogen (silver zeolite powder)
- Where
- 2 sites in Romania
- Volunteers
- 58 people
- Sponsor
- Signorini Medicale S.r.l.
Deep Partial-thickness Burn
StrataGraft® Skin Tissue Expanded Access at Specific Study Sites ( StrataCAT )
An autograft is a piece of skin taken from a healthy area of the body to be used to treat severe burns on another part of the same body.
- Trial name
- NCT04123548
- Testing
- StrataGraft skin tissue
- Where
- 10 sites in United States
- Volunteers
- 52 people
- Sponsor
- Stratatech, a Mallinckrodt Company
Breast Cancer, Radiotherapy; Adverse Effect, Dermatitis or Eczema
Evaluation of Mepitel Film® in Preventing Epidermitis in Patients Receiving Radiation Therapy for Breast Cancer
The purpose of this research is to evaluate the use of Mepitel Film® in preventing radiation epidermitis in patients receiving radiation treatment for breast cancer.
- Conditions
- Breast Cancer, Radiotherapy; Adverse Effect, Dermatitis or Eczema, Radiotherapy Side Effect, Radiation Burn
- Trial name
- NCT04149522
- Testing
- Mepitel Film®
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Burn Injury, Chronic Pain
Effects of Transcranial Direct Current Stimulation (tDCS) on Neuropathic Symptoms Following Burn Injury
The purpose of this study is to see the effects of transcranial direct current stimulation (tDCS) on the pain and itching associated with burn injury. This study is part of the Boston-Harvard Burn Model System.
- Conditions
- Burn Injury, Chronic Pain, Pruritus, Itching
- Trial name
- NCT01795079
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Spaulding Rehabilitation Hospital
Burns
Safety and Efficacy Study of Fibrin Sealant (FS 4IU) for Skin Graft Fixation and Wound Healing in Subjects With Burn Wounds
The purpose of this study is to assess if Fibrin Sealant 4IU is as safe and efficacious as staples (the current standard of care) to achieve fixation of skin grafts and wound healing in subjects with burn wounds.
- Trial name
- NCT00161759
- Testing
- Sheet skin grafts affixed with Fibrin Sealant (lyophilized) with 4 IU/mL Thrombin
- Where
- 12 sites in United States
- Volunteers
- 40 people
- Sponsor
- Baxter Healthcare Corporation
Burns, Postoperative Pain
Liposomal Bupivicaine for Skin Graft Donor Sites in Burn Patients
Burn injuries are painful to patients and the sources of pain result from many areas including: the injury itself, wound care, and surgery.
- Trial name
- NCT03705637
- Testing
- Exparel
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Massachusetts General Hospital
Burns
Phase III Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Adults and Adolescents
This multicentre phase III clinical trial will target adults and adolescents of 12 years and older with severe burns to confirm the efficacy and functionality of denovoSkin™ in achieving wound closure and reducing scarring in…
- Trial name
- NCT06745557
- Testing
- denovoSkin(TM), STSG
- Where
- 19 sites in Belgium, France and 7 more
- Volunteers
- 70 people
- Sponsor
- CUTISS AG
Melanoma (Skin)
Pilot Study of Intervention to Reduce Sunburns in Melanoma Survivors
This project will pilot test whether a wearable device that tracks sun exposure and provides alerts regarding sun exposure and protection behaviors will reduce sunburns in melanoma survivors.
- Trial name
- NCT03518229
- Testing
- Microsoft Band 2 + UV messaging, Microsoft Band 2
- Sponsor
- University of Minnesota
Sunburn
Non-inferiority Clinical Trial of Dexchlorpheniramine (Cream Versus Lotion) in the Relief of Sunburn Related Symptoms
Topical antihistamines can be used to promote relief of sunburn related symptoms (erythema, itch and burning sensations). Dexchlorpheniramine maleate 1% cream is a topical antihistamine formulation approved by ANVISA in Brazil…
- Trial name
- NCT01085851
- Testing
- Dexchlorpheniramine 1% lotion, Dexchlorpheniramine 1% cream
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Mantecorp Industria Quimica e Farmaceutica Ltd.