Clinical trials: Skin Burn
Burn With Full-Thickness Skin Loss
Autologous Keratinocyte Suspension Versus Adipose-Derived Stem Cell-Keratinocyte Suspension for Post-Burn Raw Area
In this study 1. Assess the efficiency of non-cultured autologous keratinocyte suspension in treating post-burn raw area. 2. Compare the results of keratinocyte suspension alone versus Adipose-derived mesenchymal stem…
- Trial name
- NCT03686449
- Testing
- Non-cultured Autologous Keratinocyte Suspension, Adipose-Derived Stem cell-Keratinocyte Suspension, Split skin graft
- Volunteers
- 33 people
- Sponsor
- Assiut University
Skin Burn Degree Second
Stem Cell Therapy to Improve Burn Wound Healing
This study will determine the safety of allogeneic stem cell therapy from healthy donors, for 2nd degree burn wounds of less than 20% Total Body Surface Area (TBSA), at four different dose levels.
- Trial name
- NCT02104713
- Testing
- Allogeneic (MSC's) Application to the Burn Wounds
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- E.Badiavas
Full Thickness Skin Defects
The Safety of a Novel Acellular Dermal Template as Treatment for Burns and Scars
In this study the safety and feasibility of an acellular dermal template (Novomaix), combined with split thickness skin grafts, for use in patients with full thickness skin defects, is tested.
- Trial name
- NCT02164760
- Testing
- Novomaix dermal substitute in combination with STSG
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 13 people
- Sponsor
- Association of Dutch Burn Centres
Full Thickness Skin Defects
A Study to Evaluate the Efficacy of an Acellular Dermal Template for the Treatment of Full Thickness Skin Defects
In this study the efficacy of an acellular dermal template (Novomaix), combined with split thickness skin grafts, for use in patients with full thickness skin defects, is tested.
- Trial name
- NCT02373566
- Testing
- Novomaix dermal substitute in combination with STSG
- Where
- 3 sites in Germany, Netherlands and 1 more
- Volunteers
- 11 people
- Sponsor
- Association of Dutch Burn Centres
Skin Wound, Burns
StrataGraft® Skin Tissue as an Alternative to Autografting Deep Partial-Thickness Burns
The proposed study is designed as a phase Ib open-label, dose-escalation, multicenter study evaluating the safety, tolerability, and efficacy of StrataGraft skin tissue in promoting the healing of the deep partial-thickness…
- Conditions
- Skin Wound, Burns, Trauma-related Wound
- Trial name
- NCT01437852
- Testing
- StrataGraft Skin Tissue
- Where
- 6 sites in United States
- Volunteers
- 30 people
- Sponsor
- Stratatech, a Mallinckrodt Company
Thermal Injury, Skin Burn
Gellan Contact Study
The primary objective of this study will be to establish the safety of the two different Gellan formulations (sheet and fluid gel) following its application to the epidermis of healthy volunteers.
- Trial name
- GCS (NCT04044014)
- Testing
- Gellan sheet, Gellan fluid gel, Mepitel One
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Skin Burns
ST266 in UV-induced Inflammation
This phase II clinical study will include fifteen healthy light skinned adult volunteers. At screening subjects will be given a sunburn test.
- Trial name
- NCT02389777
- Testing
- ST266 immediate, ST266 delayed
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Noveome Biotherapeutics, formerly Stemnion
Visible Difference, Acceptance and Commitment Therapy
Acceptance-based Self-help for Individuals With Visible Difference and Social Anxiety
The acceptance and commitment therapy (ACT) model theoretically fits with treating appearance-related anxiety in individuals with a visible difference.
- Conditions
- Visible Difference, Acceptance and Commitment Therapy, ACT, Skin Condition
- Trial name
- NCT03205839
- Testing
- Acceptance-based self-help intervention
- Where
- United Kingdom
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Skin Ulcer, Burns
Effectiveness Comparison of Skin Micro-grafts vs Meshed Split Thickness Skin Grafts
This is a double-blind randomized controlled clinical trial, that compares the percentage of epithelialization of skin defects using the conventional meshed split thickness skin grafts vs skin micro grafts.
- Trial name
- NCT02813213
- Testing
- Skin micro Grafts, Standard skin graft
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Burn Injury, Skin Graft
A Soft Silicone Wound Contact Layer Containing Silver in the Treatment of Skin Grafts in Surgical Burn Patients.
Part A The primary objective of Part A will be to verify performance and safety of Mepitel® Ag, a meshed, non- adherent soft silicone wound contact layer containing silver in the treatment of skin grafts in surgical burn…
- Trial name
- MpTAg03 (NCT02210208)
- Testing
- Mepitel® Ag, Mepilex® Transfer Ag
- Where
- 4 sites in United States
- Volunteers
- 25 people
- Sponsor
- Molnlycke Health Care AB
Burns, Skin Burn Requiring Skin Graft
Study of Low Adherent Dressing Versus the Standard of Care for the Management of Skin Grafts Over Thermal Burns
The purpose of this study is to evaluate the P6 Low Adherent Study Dressing relative to the Standard of Care (SOC, Mafenide Acetate 5% Solution) for the management of skin grafts in burn wounds resulting from thermal burn…
- Trial name
- NCT01654094
- Testing
- P6 Low Adherent Dressing, Standard of Care (SOC)
- Where
- 4 sites in United States
- Volunteers
- 80 people
- Sponsor
- Milliken Healthcare Products, LLC
Split-thickness Skin Graft Donor Sites, Burns
Molecular, Histologic, and Clinical Analysis of Negative Pressure Wound Therapy (NPWT) for Split-thickness Skin Graft (STSG) Donor Sites
The purpose of this single-center, randomized, prospective cohort study is to evaluate the clinical outcome and negative-pressure wound therapy (NPWT) mediated modulation of the biologic milieu of a modified NPWT dressing on…
- Trial name
- NCT02712164
- Testing
- Modified NPWT dressing, Tegaderm
- Sponsor
- Brigham and Women's Hospital
Full-thickness Skin Loss Due to Burn, Unspecified Site
Glyaderm Clinical Evaluation Multicenter Study
The healing of full thickness skin defects treated with a split thickness skin graft (STSG) is frequently associated with excessive scarring and contraction.
- Trial name
- NCT01616043
- Testing
- Glyaderm, STSG
- Where
- 6 sites in Belgium, Greece and 2 more
- Volunteers
- 40 people
- Sponsor
- Euro Tissue Bank
Skin Burn Degree Second
Compare the Efficacy of Mepilex and Keramatrix in Second Degree Burn Wounds
The purpose of this study is to determine the extent to which Keramatrix dressing promotes the healing of second-degree burn wounds in pediatric patients.
- Trial name
- NCT01790763
- Testing
- Keramatrix, Mepilex
- Where
- United States
- Sponsor
- The University of Texas Medical Branch, Galveston
Burn, Skin Graft
The Effects of Therapeutic Resources on Structure and Function of Normal and Burned Skin
Burning produces changes in the biomechanical properties of the skin causing limitation of movement. The increase in skin suppleness is very important in the rehabilitation process, since its increase makes therapeutic…
- Trial name
- NCT02185950
- Testing
- ultrasound, paraffin, endermotherapy
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Skin and Subcutaneous Tissue Bacterial Infections, Wound Infection
A Study of Safety, Tolerability, and Efficacy of AFN-12520000 in the Treatment of Acute Bacterial Skin and Skin Structure Infections Due to Staphylococci
The purpose of the study is to determine the safety, tolerability and effectiveness of AFN-12520000 for in the treatment of Staphylococcal infections of the skin.
- Conditions
- Skin and Subcutaneous Tissue Bacterial Infections, Wound Infection, Cutaneous Abscess, Burn Infection
- Trial name
- NCT01519492
- Testing
- AFN-12520000
- Where
- 14 sites in United States, Canada
- Volunteers
- 103 people
- Sponsor
- Affinium Pharmaceuticals, Ltd
Transplantation Infection, Wound of Skin
Graft Take and Microbiology in Burns
SPLIT-THICKNESS SKIN GRAFT TAKE AND MICROBIOLOGICAL EVALUATION IN BURNED PATIENTS INTRODUCTION: Infection is cause of increased morbidity and mortality in burn patients, and its control is a major challenge also for skin graft…
- Conditions
- Transplantation Infection, Wound of Skin, Burns, Graft Loss
- Trial name
- NCT01301118
- Volunteers
- 30 people
- Sponsor
- Federal University of São Paulo
Skin Burns
The Counter-irritating Efficacy of Topical Povidone-iodine in Thermal Burns
Skin burns are one of the causes of disability, suffering and death in humans. Anecdotal, uncontrolled studies have shown the efficacy of povidone-iodine ointment in human skin burns, provided the preparation was applied shortly…
- Trial name
- NCT01350713
- Testing
- povidone iodine
- Where
- Israel
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Burn Wound and Skin Graft Healing
Healing of Burns and the Effect of Shockwave Therapy on the Recovery of Skin Grafts
The study is to review whether musculoskeletal shockwave therapy (ESWT) can speed up the healing of second-degree burns as well as skin-graft donor sites.
- Trial name
- NCT01242423
- Testing
- extracorporeal shockwave therapy
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Unfallkrankenhaus Berlin
Skin Graft
Effect of Platelet Rich Plasma and Keratinocyte Suspensions on Wound Healing
This prospective randomized trial evaluated the impact of autologous keratinocytes suspended in platelet concentrates on healing skin graft donor site wounds.
- Trial name
- NCT00856934
- Testing
- Autologous Platelet Rich Plasma, Keratinocyte suspension, Standard dressings
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois