Clinical trials: Skin Burns
Thermal Burn
Safety and Feasibility of ADRCs Treatment To Patients With Thermal Wounds
The primary objective of the protocol is to evaluate preliminary safety and feasibility of ADRCs via intravenous delivery in the treatment of deep partial and full thickness thermal wounds.
- Trial name
- NCT03435172
- Testing
- Device-ADRCs intravenously infusion
- Where
- 5 sites in United States
- Volunteers
- 15 people
- Sponsor
- Cytori Therapeutics
Burns
Human Amniotic Versus Synthetic Membrane as a Transient Skin Cover for Pediatric Burns
This is a randomised trial that aims to evaluate whether a transient skin cover made out of human amniotic membranes is effective in managing burns among pediatric patients.
- Trial name
- NCT02904941
- Testing
- Amniotic Membrane Dressing, Synthetic Dressing, Standard Wound Care
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- Universidad de Valparaiso
Sunburn
Efficacy and Safety of Diclofenac Sodium (0.1%) Gel in Patients With UV Induced Painful Sunburn
Diclofenac sodium 0.1% will be applied to sunburned skin when the intensity of pain reaches a certain level in order to evaluate the efficacy and safety of the treatment on this induced pain.
- Trial name
- NCT00441051
- Testing
- Diclofenac sodium 1mg/g
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Novartis
Burn Injury, Soft Tissue Injury
Phase I Study for Autologous Dermal Substitutes and Dermo-epidermal Skin Substitutes for Treatment of Skin Defects
The purpose of this study is the evaluation of the safety of autologous tissue-engineered dermal substitutes "denovoDerm" (first arm) and dermo-epidermal skin substitutes "denovoSkin" (second arm) transplanted onto the wound bed…
- Conditions
- Burn Injury, Soft Tissue Injury, Skin Necrosis, Scars
- Trial name
- NCT02145130
- Testing
- denovoDerm, denovoSkin
- Where
- 2 sites in Switzerland
- Volunteers
- 12 people
- Sponsor
- University of Zurich
Thermal Burns
Continuous Lidocaine Infusion for Management of Perioperative Burn Pain
Thermal injury results in one of the most intense and prolonged forms of pain the body can experience. Opioid narcotics are the most powerful drugs for acute and chronic pain, and their use in the perioperative period has been…
- Trial name
- NCT02059902
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- HealthPartners Institute
Burn Scar
Effect of Pulsed Electromagnetic Field on Pruritus in Burn Scars
This study will be conducted to evaluate the effectiveness of pulsed electromagnetic field therapy in pruritus in patients with burn scars.
- Trial name
- PEM (NCT07443358)
- Testing
- pulsed electromagnetic field therapy, standard care
- Volunteers
- 40 people
- Sponsor
- Cairo University
Burns
Dermal Substitute and Topical Negative Pressure in Burns
The purpose of this study is to determine whether a treatment of full thickness wounds by the dermal substitute Matriderm, split skin graft and VAC treatment will improve scar quality, demonstrated by a significant increase of…
- Trial name
- VAC-M (NCT00548314)
- Testing
- dermal matrix, Split skin graft, VAC therapy (KCI)
- Where
- Netherlands
- Volunteers
- 86 people
- Sponsor
- Association of Dutch Burn Centres
Burn Injuries
Testing an Innovative Biomarker: Expression of HIF-1α and Its Isoforms in the Blood and Skin Tissue of Major Burns
Burn injury with full-thickness skin damage that encompass large body surface areas can induce local and systemic perturbations that are costly in terms of human suffering as well as in strains on the health care system.
- Trial name
- HIF (NCT02870439)
- Testing
- Blood drawn
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Acute Burns
Using Autologous Platelet Rich Plasma (PRP) Gel to Treat Deep 2nd and 3rd Degree Burns
This study will demonstrate the safety of the application of autologous platelet rich plasma (PRP) gel following excision and autologous skin grafting of acute deep 2nd and 3rd degree burns.
- Trial name
- NCT01843686
- Testing
- Magellan®
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- Arteriocyte, Inc.
Trauma-related Wound, Burns
StrataGraft® Skin Tissue as an Alternative to Autografting Full-thickness Complex Skin Defects
About 20 participants will be enrolled in this trial if they have had an accident that damages both the dermal (outside) and epidermal (inside) layers of skin on up to 49% of their body.
- Conditions
- Trauma-related Wound, Burns, Skin Wound
- Trial name
- NCT03005054
- Testing
- StrataGraft Skin Tissue, Autograft
- Where
- 4 sites in United States
- Volunteers
- 3 people
- Sponsor
- Stratatech, a Mallinckrodt Company
Blisters, Second Degree Burns
Evaluation and Comparison of Keloids and Second Degree Burns Blisters Fluid
It is well documented that following thermal burns injury the development of hypertrophic scars and keloid (HSK) ranges between 40 to 90%.
- Conditions
- Blisters, Second Degree Burns, Wounds
- Trial name
- NCT01627769
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Melanoma (Skin)
Wearable Device Intervention to Improve Sun Behaviors in Melanoma Survivors
Over 5 million new cases of skin cancer are diagnosed in the United States each year, more than all other cancers combined. Most of these cases are caused by excess exposure to ultraviolet radiation from the sun and artificial…
- Trial name
- NCT03927742
- Testing
- Shade + app with messaging, Shape + app without messaging
- Where
- United States
- Volunteers
- 368 people
- Sponsor
- University of Minnesota
Burns, Burns Second Degree
CellMist™ Autologous Cells to Treat Deep Second-Degree Burns
The overall purpose of this study is to evaluate the safety of the CellMist™ System in the treatment of deep second degree burns (II°B) in a prospective, multicenter, feasibility pilot study.
- Conditions
- Burns, Burns Second Degree, Burns Deep Second Degree
- Trial name
- CELLMIST1 (NCT04890574)
- Testing
- CellMist™ System
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- RenovaCare, Inc
Burns
Comparison of Skin Substitutes Used in Burn Care
The purpose of this study is to determine if using a DERMAL LAYER under skin grafts: 1. will reduce scar formation of skin grafts 2. will reduce burn wound contractures 3.
- Trial name
- Quad (NCT00676013)
- Testing
- Integra, AlloDerm, Homograft
- Where
- 2 sites in United States
- Volunteers
- 158 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Burn
Effect of Therapeutical Paraffin in the Malleability of Burned Skin
Effect of therapeutical paraffin wax bath in the malleability of burned skin
- Trial name
- NCT03026270
- Testing
- Paraffin
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Burns, Trauma
Split Thickness Donor Site Healing With MIST Study
Subjects requiring skin grafting due to burns, trauma, or chronic venous ulcers with split thickness donor sites expected to be between 20 and 200 square cm will be consecutively screened for study eligibility.
- Conditions
- Burns, Trauma, Venous Ulcers
- Trial name
- NCT01214980
- Testing
- MIST Therapy, Standard of care
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Celleration, Inc.
Visible Difference, Acceptance and Commitment Therapy
Acceptance-based Self-help for Individuals With Visible Difference and Social Anxiety
The acceptance and commitment therapy (ACT) model theoretically fits with treating appearance-related anxiety in individuals with a visible difference.
- Conditions
- Visible Difference, Acceptance and Commitment Therapy, ACT, Skin Condition
- Trial name
- NCT03205839
- Testing
- Acceptance-based self-help intervention
- Where
- United Kingdom
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Sunburn
Dermal Irritation, Sensitization and Cumulative Irritation Potential of 6% Bemotrizinol
The purpose of this clinical trial is to evaluate the dermal safety of Bemotrizinol (6%).
- Trial name
- NCT05260359
- Testing
- 6% Bemotrizinol (BEMT) in a basic sunscreen oil formulation, 6% Bemotrizinol (BEMT) dispersion in petrolatum, Sunscreen oil vehicle with 10% ethanol as penetration enhancer without BEMT
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Burn With Full-Thickness Skin Loss
Autologous Keratinocyte Suspension Versus Adipose-Derived Stem Cell-Keratinocyte Suspension for Post-Burn Raw Area
In this study 1. Assess the efficiency of non-cultured autologous keratinocyte suspension in treating post-burn raw area. 2. Compare the results of keratinocyte suspension alone versus Adipose-derived mesenchymal stem…
- Trial name
- NCT03686449
- Testing
- Non-cultured Autologous Keratinocyte Suspension, Adipose-Derived Stem cell-Keratinocyte Suspension, Split skin graft
- Volunteers
- 33 people
- Sponsor
- Assiut University
Sunburn
Dermal Penetration of the Titanium Dioxide in Anthelios SX SPF40 Cream
To determine the penetration of micronized and pigmentary TiO2 in Formulas 283419 2 and 760.001 into the stratum corneum of Compromised (Induced Sunburn) human skin via skin stripping of human subjects.
- Trial name
- NCT01021787
- Testing
- Titanium dioxide
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Loreal USA