Clinical trials: Skin Cancer Prevention
Breast Cancer, Colorectal Cancer
Improving Cancer Screening and Prevention During the COVID-19 Pandemic in Underserved Populations of Rhode Island
Lifespan Cancer Institute serves over 50% of cancer patients in the state. Rhode Island is known for strong medical care and high rates of cancer screening with mammography and colonoscopy.
- Conditions
- Breast Cancer, Colorectal Cancer, Covid19
- Trial name
- NCT04587258
- Testing
- Informational videos and social media campaigns encouraging cancer screening.
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rhode Island Hospital
Skin Cancer, Skin Cancer Prevention
Developing and Testing the Effectiveness of a Skin Cancer Self-Detection Educational Program
Skin cancer is a significant public health concern, even in an Asian society like Singapore where it ranks among the top 10 cancers.
- Conditions
- Skin Cancer, Skin Cancer Prevention, Benign Skin Growth
- Trial name
- NCT07247123
- Testing
- Skin Cancer Self-Detection Educational Program with gain-framing, Skin Cancer Self-Detection Educational Program with loss-framing, Wait-list Control
- Where
- Singapore
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Radiodermatitis, Breast Cancer
Photobiomodulation Therapy for the Prevention of Acute Radiodermatitis in Breast Cancer Patients Undergoing Radiotherapy
Radiodermatitis (RD), an inflammatory skin reaction, occurs in more than 90 percent of cancer patients treated with radiotherapy (RT). This is the result of the radiation causing damage to the epidermal basal skin stem cells.
- Trial name
- LABRA (NCT03924011)
- Testing
- Photobiomodulation therapy (PBMT)
- Where
- 2 sites in Belgium
- Volunteers
- 71 people
- Sponsor
- Hasselt University
Colorectal Cancer Control and Prevention, Colorectal Cancer Recurrent
[68Ga]Ga-GZP PET for Early Response Prediction in Colorectal Cancer During Neoadjuvant Therapy
This diagnostic study investigates the value of 68Ga-NOTA-GZP PET imaging in predicting and evaluating immunotherapy response in malignant tumors by enrolling pathologically confirmed patients scheduled for immunotherapy and…
- Conditions
- Colorectal Cancer Control and Prevention, Colorectal Cancer Recurrent, Colorectal Cancer Metastatic, Colorectal Cancer Screening
- Trial name
- NCT06982053
- Testing
- Received 68Ga-NOTA-GZP PET scanning
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Paravertebral Catheter Insertion, Mastectomy
Prevention of Post-Mastectomy Breast Pain Using Ambulatory Continuous Paravertebral Blocks
Research study to determine if putting local anesthetic-or numbing medication-through a tiny tube placed next to the nerves that go to a breast prior to and following a mastectomy will decrease subsequent pain.
- Conditions
- Paravertebral Catheter Insertion, Mastectomy, Breast Cancer
- Trial name
- NCT01231204
- Testing
- Ropivicaine 0.4% Continuous Infusion
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Diego
Breast Cancer, Colon Cancer
Cancer Prevention and Treatment Among African American Older Adults: Treatment Trial
The Centers for Medicare and Medicaid Services (CMS) has awarded cooperative agreements to 6 sites from across the country (Salt Lake City, UT, Molokai, HI, Houston, TX, Newark, NJ, Detroit, MI, and Baltimore City) to participate…
- Conditions
- Breast Cancer, Colon Cancer, Rectum Cancer, Cervix Cancer
- Trial name
- CPTD (NCT00509444)
- Testing
- Educational materials, educational materials, plus patient navigation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
BRCA1 Mutation, Breast Cancer
Studying the Effect of Denosumab on Preventing Breast Cancer in Women With a BRCA1 Germline Mutation
This phase III trial compares denosumab to placebo for the prevention of breast cancer in women with a BRCA1 germline mutation. A germline mutation is an inherited gene change which, in the BRCA1 gene, is associated with an…
- Conditions
- BRCA1 Mutation, Breast Cancer, Breast Diseases, Breast Neoplasms
- Trial name
- BRCA-P (NCT04711109)
- Testing
- Denosumab, Quality-of-Life Assessment
- Where
- 47 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Alliance for Clinical Trials in Oncology
Dermatologic Complications, Malignant Neoplasm
Menadione Topical Lotion in Treating Skin Discomfort and Psychological Distress in Patients With Cancer Receiving Panitumumab, Erlotinib Hydrochloride, or Cetuximab
This clinical trial studies menadione topical lotion in treating skin discomfort and psychological distress in patients with cancer receiving panitumumab, erlotinib hydrochloride, or cetuximab.
- Conditions
- Dermatologic Complications, Malignant Neoplasm, Pain
- Trial name
- NCT01393821
- Testing
- menadione topical lotion, questionnaire administration, management of therapy complications
- Where
- 2 sites in United States
- Volunteers
- 27 people
- Sponsor
- Mayo Clinic
Lymphedema, Breast Cancer
Lymphedema Prevention After Lymph Node Emptying
ABSTRACT Object: The impact of morbidity and the deterioration in health-related quality of life for patients with lymphedema after axillary lymph node dissection for breast cancer justify the implementation of prevention…
- Conditions
- Lymphedema, Breast Cancer, Prevention, Rehabilitation
- Trial name
- NCT04785599
- Testing
- Exercices, Informative talk, Compression garment
- Volunteers
- 70 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Breast Cancer
My Lifestyle Intervention of Food and Exercise
Breast cancer risk, and risk of related health problems (e.g., heart disease), is highest among women with a history of breast cancer (stages 1-3) who are also overweight or obese.
- Trial name
- MyLIFE (NCT01630499)
- Testing
- Tailored Lifestyle Intervention (TLI), Commercial Weight Loss Program (CWLP)
- Where
- 2 sites in United States
- Volunteers
- 87 people
- Sponsor
- University of Florida
Hand-Foot Syndrome, Breast Cancer
Ice Plant Intensive Cream for the Prevention of Hand-Foot Syndrome in Breast Cancer: Pilot Randomized Controlled Trial
The present pilot study investigates the feasibility of a prospective larger confirmatory study on the efficacy of Dr. Hauschka Med Ice Plant Intensive Cream for the prevention of hand-foot syndrome in patients with breast…
- Trial name
- WIn-HFS (NCT05755646)
- Testing
- Ice Plant Intensive Cream plus Standard Care, Standard Care
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- University Hospital Tuebingen
Breast Cancer
Study to Evaluate the Effect of Metformin in the Prevention of HG in HR[+]/HER2[-] PIK3CA-mut Advanced BC Patients
Men and post- or induced menopausal women with ER[+] and/or PgR[+], HER2[- ] advanced BC, with centrally-confirmed PI3KCAMut who progressed to an aromatase inhibitor (AI) regimen.
- Trial name
- METALLICA (NCT04300790)
- Testing
- Alpelisib, Metformin, Fulvestrant
- Where
- 19 sites in Spain
- Volunteers
- 69 people
- Sponsor
- MedSIR
Cancer
Donor Natural Killer Cell Infusion in Preventing Relapse or Graft Failure in Patients Who Have Undergone Donor Bone Marrow Transplant
RATIONALE: Giving donor natural killer cells to patients who have undergone donor bone marrow transplant may make the transplant work better and keep cancer cells from coming back.
- Trial name
- NCT00569283
- Testing
- therapeutic allogeneic lymphocytes
- Where
- 2 sites in South Korea
- Volunteers
- 18 people
- Sponsor
- Asan Medical Center
Body Weight Changes, Breast Neoplasms
The Use of Smart Scales for Weight Gain Prevention in African American Breast Cancer Survivors
The purpose of this study is to test the feasibility of two 6-month behavioral interventions for weight gain prevention (self-regulation plus activity monitoring or self-regulation) among African American breast cancer survivors…
- Trial name
- NCT02030353
- Testing
- Self-regulation plus activity monitoring, Self-regulation
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Heart Failure
Ability of L-carnitine to Prevent Heart Damage in Breast Cancer Patients Receiving Anthracycline Chemotherapy
Breast cancer is very common and afflicts 1 in 9 North American women. The treatment of breast cancer often requires the use of chemotherapy including "anthracyclines".
- Trial name
- NCT00247975
- Testing
- L-carnitine
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Skin Cancer, Cutaneous Squamous Cell Carcinoma (CSCC)
A Randomized Controlled Trial of Topical 5% Niacinamide for Skin Cancer Prevention in Transplant Recipients
A Randomized Controlled Trial of Topical 5% Niacinamide for Skin Cancer Prevention in Organ Transplant Recipients This study is designed to evaluate whether a topical 5% niacinamide cream can help prevent skin cancer in organ…
- Conditions
- Skin Cancer, Cutaneous Squamous Cell Carcinoma (CSCC), Actinic Keratosis (AK), Organ Transplant Recipient
- Trial name
- NCT07286318
- Testing
- Topical niacinamide 5% cream, Sunscreen
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Marissa Lobl
Breast Cancer Diagnosis, Breast Cancer Prevention
Contrast Enhanced Mammography in the Evaluation of Cancer of Unknown Primary Syndrome
This study aims to evaluate the role of Contrast-Enhanced Mammography (CEM) in identifying the primary tumor site in patients presenting with Cancer of Unknown Primary (CUP) syndrome.
- Trial name
- CEM_CUP_syndr (NCT06843096)
- Testing
- Contrast-Enhanced Mammography (CEM)
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- Graziella di Grezia
Breast Cancer
Omega 3 Fatty Acids and ERPR(-)HER2(+/-) Breast Cancer Prevention
The study aims to determine biological changes associated with a low vs high dose of omega 3 fatty acids, docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), over 12 months in women at risk for recurrent breast cancer.
- Trial name
- NCT02295059
- Testing
- omega 3 fatty acids
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- City of Hope Medical Center
Breast Carcinoma, Head and Neck Carcinoma
StrataXRT for the Prevention and Treatment of Radiation Dermatitis in Breast Cancer or Head and Neck Cancer Patients
This clinical trial studies the effect of StrataXRT in preventing and treating radiation dermatitis in breast cancer or head and neck cancer patients. Radiotherapy is often associated with multiple side effects.
- Conditions
- Breast Carcinoma, Head and Neck Carcinoma, Radiation-Induced Dermatitis
- Trial name
- NCT05073172
- Testing
- Calendula Ointment, Petrolatum-Mineral Oil-Lanolin-Ceresin Ointment, Polyethylene Glycol Hydrogel
- Where
- United States
- Sponsor
- OHSU Knight Cancer Institute
Actinic Keratosis
Testing the Efficacy of Topical Calcipotriene Plus 5-Fluorouracil Combination to Activate the Immune System Against Precancerous Skin Lesions in Organ Transplant Recipients
This phase IIA study evaluates the effects of calcipotriene plus 5- fluorouracil immunotherapy for skin cancer prevention in organ transplant recipients.
- Trial name
- NCT05699603
- Testing
- Biopsy, Calcipotriene, Fluorouracil
- Where
- 4 sites in United States
- Volunteers
- 56 people
- Sponsor
- University of Arizona