Clinical trials: Skin Diseases, Bacterial
Hidradenitis Suppurativa (HS)
Safety and Efficacy of Roflumilast Foam 0.3% in Adolescent and Adult Subjects With Hidradenitis Suppurativa
This study investigates the efficacy of topical roflumilast foam in patients with HS.
- Trial name
- ARQ-MA-000260 (NCT07689188)
- Testing
- Roflumilast 0.3% topical foam
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Harrison Dermatology
Hidradenitis Suppurativa
Exploratory Trial Evaluating Cosentyx (Secukinumab) for Patients With Moderate-to-Severe Hidradenitis Suppurativa
This is a pilot study in which the the safety and feasibility of secukinumab in HS patients as well as information about the effect size will be determined in order to inform a future larger randomized control trial with an…
- Trial name
- NCT03099980
- Testing
- secukinumab
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Tufts Medical Center
Latent Tuberculosis Infection, End Stage Renal Disease (ESRD)
Prevalence of Latent Tuberculosis Infection Among Hemodialysis Patients
This observational cross-sectional study aims to determine the prevalence of latent tuberculosis infection (LTBI) among patients undergoing regular hemodialysis at Sohag University Hospital, using the tuberculin skin test (TST).
- Conditions
- Latent Tuberculosis Infection, End Stage Renal Disease (ESRD), Hemodialysis
- Trial name
- NCT07210970
- Testing
- Tuberculin Skin Test (TST)
- Volunteers
- 200 people
- Sponsor
- Sohag University
Onychomycosis
Safety and Efficacy Study of Subjects With Onychomycosis of the Great Toenail
The purpose of the study is to determine the safety and efficacy of 5.0% and 7.5% AN2690 Solution in the treatment of distal, subungual onychomycosis of the great target toenail.
- Trial name
- NCT00679523
- Testing
- AN2690 Solution, 5.0%, AN2690 Solution, 7.5%
- Where
- 9 sites in Mexico
- Volunteers
- 60 people
- Sponsor
- Pfizer
Atopic Dermatitis, Psoriasis
Determinants of Chronic Inflammatory Skin Disease Trajectories
Although it is well known that the clinical expression and course of chronic inflammatory skin diseases are highly variable, there are insufficient epidemiological data on this, and the factors that determine the manifestation…
- Conditions
- Atopic Dermatitis, Psoriasis, Lichen Planus, Alopecia Areata
- Trial name
- NCT05928169
- Testing
- Topical and systemic drugs
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Wounds, Hidradenitis Suppurativa
Wound Etiology and Healing Study
The purpose of the WE-HEAL Study is to help researchers use human tissue samples and health records to study the reasons why some patients heal quickly and some have problems healing wounds.
- Conditions
- Wounds, Hidradenitis Suppurativa, Hidradenitis, Acne Inversa
- Trial name
- WE-HEAL (NCT01352078)
- Where
- United States
- Volunteers
- 743 people
- Sponsor
- George Washington University
Hidradenitis Suppurativa
Treatment of Hidradenitis Suppurativa Using Etanercept
Therapy with etanercept, a TNF inhibitor will reverse the inflammation, symptoms and quality of life and allow healing of HS.
- Trial name
- NCT00949546
- Testing
- etanercept
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Penn State University
Hidradenitis Suppurativa
Studying Complement Inhibition in Patients With Moderate to Severe Hidradenitis Suppurativa
The trial enrolls patients with moderate to severe Hidradenitis Suppurativa (HS). The primary goal of the trial is to evaluate the safety and tolerability of IFX-1 administered over 8 weeks in these patients.
- Trial name
- NCT03001622
- Testing
- IFX-1
- Where
- Greece
- Volunteers
- 12 people
- Sponsor
- InflaRx GmbH
Tinea Pedis, Athlete's Foot
Once a Day Topical Treatment for Athlete's Foot Fungus Inbetween the Toes in Males and Females
The topical cream, Sertaconazole (Ertaczo), has been FDA approved for the treatment of athlete's foot using twice a day dosing for 4 weeks.
- Conditions
- Tinea Pedis, Athlete's Foot, Foot Fungus, Ringworm
- Trial name
- NCT00856596
- Testing
- Sertaconazole nitrate cream 2%
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jamaica Hospital Medical Center
Cellulitis, Erysipelas
Duration of ANtibiotic Therapy for CEllulitis
Cellulitis is among the most common infections leading to hospitalization, yet the optimal duration of therapy remains ill defined.
- Trial name
- DANCE (NCT02032654)
- Testing
- Flucloxacillin
- Where
- 11 sites in Netherlands
- Volunteers
- 151 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Leishmaniasis, Leptospirosis
Serological Measurement of Montpellier Professionals' Contacts with Infectious Agents Responsible for Animal-borne Diseases
Zoonoses and arboviroses refer to a group of diseases transmitted from animals to humans, either directly or indirectly (via mosquitoes, ticks or contact with contaminated environments).
- Conditions
- Leishmaniasis, Leptospirosis, Brucellosis, Q Fever
- Trial name
- SEZAM (NCT06859619)
- Testing
- Peripheral venous blood sample
- Where
- France
- Volunteers
- 183 people
- Sponsor
- University Hospital, Montpellier
Hidradenitis Suppurativa
Hidradenitis Suppurativa Phase 2b Study of Izokibep
Izokibep is a potent and selective inhibitor of interleukin 17A (IL-17A) that is being developed for treatment of hidradenitis suppurativa (HS).
- Trial name
- NCT05355805
- Testing
- Izokibep
- Where
- 44 sites in United States, Canada and 4 more
- Volunteers
- 205 people
- Sponsor
- ACELYRIN Inc.
Tinea Cruris, Jock Itch
Evaluation of Efficacy and Safety of Naftin 1% Cream in Adolescent Subjects With Tinea Cruris
To see how well Naftin 1% cream works when applied once daily to the affected area. The results will be compared to those using a placebo cream, which is a cream with no active ingredient. Safety will also be measured.
- Trial name
- NCT01885156
- Testing
- Naftin 1% Cream
- Where
- 5 sites in Belize, Dominican Republic and 1 more
- Volunteers
- 65 people
- Sponsor
- Merz North America, Inc.
Tinea Capitis
Population Pharmacokinetics of Terbinafine in Children With Tinea Capitis
The goal of this observational study is to characterize the population pharmacokinetics (PPK) of terbinafine in pediatric patients with tinea capitis, evaluate its efficacy and safety, and identify covariates affecting drug…
- Trial name
- NCT07046988
- Testing
- Terbinafine Tablets
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shandong University
Erythema Migrans, Erythema Chronicum Migrans
Comparing 3 Antibiotic Regimes for Erythema Migrans in General Practice
Tick borne diseases are increasing in Norway. Lyme borreliosis is the most common infection. Erythema migrans is mainly diagnosed and treated in general practice.
- Conditions
- Erythema Migrans, Erythema Chronicum Migrans, Borreliosis, Lyme Disease
- Trial name
- NorTick_EM (NCT01368341)
- Testing
- Doxycycline, Phenoxymethylpenicillin, Amoxicillin
- Where
- Norway
- Volunteers
- 225 people
- Sponsor
- Morten Lindbaek
Hidradenitis Suppurativa, Scarring
Efficacy and Tolerability of a Fractional Ablative Erbium Laser for Axillary Scarring for Hidradenitis Suppurativa Patients
Single center, open-label, baseline-controlled study evaluating the use of a Sciton fractionated ablative laser in the treatment of Hidradenitis Suppurativa (HS) scarring.
- Trial name
- NCT05470322
- Testing
- Er: YAG laser
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Onychomycosis
Treatment of Onychomycosis Using a 0.65 Millisecond Pulsed Nd:YAG 1064 nm Laser
The investigators would like to test the treatment of onychomycosis using a 0.65 millisecond pulsed 1064 nm laser fitted with a special onychomycosis handpiece.
- Trial name
- NCT01666002
- Testing
- Laser Treatment (Pulsed Nd:YAG 1064 nm Laser)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Stanford University
Rheumatic Arthritis, Rheumatoid Arthritis (RA) Prevention
Efficacy and Safety of Resveratrol in Patients With Rheumatoid Arthritis.
The aim of the current study is to evaluate the effects of resveratrol on the clinical outcome(s) of patients with moderate rheumatoid arthritis. Objectives : 1.
- Conditions
- Rheumatic Arthritis, Rheumatoid Arthritis (RA) Prevention, Inflamation, Antioxidant
- Trial name
- NCT07089381
- Testing
- Resveratrol 1 gm., Methotrexate
- Where
- Egypt
- Volunteers
- 118 people
- Sponsor
- Ain Shams University
Hidradenitis Suppurativa (Acne Inversa)
Efficacy, Safety, and Pharmacokinetics Study of CJM112 in Hidradenitis Suppurativa Patients
This is a randomized, double blind, multicenter study in patients with moderate to severe chronic hidradenitis suppurativa in parallel groups, to determine the efficacy and safety of multiple doses of CJM112 in comparison to…
- Trial name
- NCT02421172
- Testing
- CJM112
- Where
- 16 sites in United States, Denmark and 3 more
- Volunteers
- 66 people
- Sponsor
- Novartis Pharmaceuticals
Rheumatic Heart Diseases, Scabies
Assessment of the Prevalence of Rheumatic Heart Disease in School Settings in Mayotte and the Acquisition of Ultrasound Sequences Guided by Artificial Intelligence
The prevalence of chronic rheumatic heart disease (RHD) on the island of Mayotte is unknown, but it appears to be high and is responsible for significant morbidity and mortality.
- Trial name
- PRECARE-MAYIA (NCT07904975)
- Testing
- Ultrasound performed bycardiologis for diagnosis of rheumatic heart disease
- Volunteers
- 900 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion