Clinical trials: Skin Diseases, Papulosquamous
Psoriatic Arthritis, Osteoarthitis
CARTIZ Registry: Cartilage, Arthropathy and Imaging Under Tirzepatide in Zone-stratified Cohorts - A Four-Institute Mexican Observational Registry
CARTIZ is a prospective observational clinical registry of adults in Mexico receiving tirzepatide (a dual GLP-1/GIP receptor agonist) under an independent clinical indication - typically type 2 diabetes, insulin resistance…
- Conditions
- Psoriatic Arthritis, Osteoarthitis, Knee, Diabetes (DM)
- Trial name
- CARTIZ (NCT07567378)
- Testing
- Tirzepatide
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- JULIO GRANADOS MONTIEL
Psoriasis
A Trial of SHR-1139 in Healthy Volunteers
The purpose of this study is to assess safety, PK and immunogenicity profile of a single dose of SHR-1139 in healthy volunteers
- Trial name
- NCT07078695
- Testing
- SHR-1139 Injection
- Where
- Australia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Atridia Pty Ltd.
Arthritis, Psoriatic
A Study of Guselkumab and Interleukin-17 (IL-17) Inhibitor Therapies in Participants With Psoriatic Arthritis in Routine Clinical Practice
The purpose of this study is to evaluate treatment persistence with guselkumab and interleukin-17 inhibitor (IL-17i) initiated at enrollment into this study (PsABIOnd).
- Trial name
- PsABIOnd (NCT05049798)
- Testing
- Guselkumab, IL-17i
- Where
- 155 sites in Argentina, Australia and 18 more
- Volunteers
- 1,314 people
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
Vaginal Atrophy, Lichen Sclerosus
Fractional / Pixel CO2 Laser Treatment of Vulvar Atrophy and Lichen Sclerosus
The study will examine the effects of fractional/pixel CO2 laser treatment in vaginal atrophy and in vulvar lichen sclerosus by means of histological and immuno-histochemical characterization of the epithelial layers and markers…
- Trial name
- NCT03063684
- Testing
- Fractional / Pixel CO2 Laser
- Where
- Israel
- Volunteers
- 16 people
- Sponsor
- Hadassah Medical Organization
PsA (Psoriatic Arthritis)
Effect of Metformin on Carotid Atherosclerosis for Non-diabetic Patients With PsA (CAMPA Study)
Background: Psoriatic arthritis (PsA) is a common chronic inflammatory disease with a prevalence up to 670 every 100,000 subjects.
- Trial name
- NCT05988684
- Testing
- Metformin
- Where
- Hong Kong
- Volunteers
- 24 people
- Sponsor
- Chinese University of Hong Kong
Pediatric Psoriasis
Clinical, Epidemiologic, and Therapeutic Characterization of Pediatric Psoriasis in the Costa Rican Social Security System
The goal of this retrospective observational study is to characterize the clinical features, severity, comorbidities, and treatment patterns of pediatric psoriasis in patients managed in the Costa Rican Social Security System.
- Trial name
- NCT07451626
- Where
- Costa Rica
- Volunteers
- 300 people
- Sponsor
- Caja Costarricense de Seguro Social
Oral Lichen Planus
Effect of Oral Zinc Supplementation as an Adjuvant to Topical Corticosteroid in Oral Lichen Planus Patients
Lichen planus is an auto-immune, chronic inflammatory disease that affects mucosal and cutaneous tissue. Erosive and atrophic oral lichen planus (OLP) are difficult to manage because patients present with symptoms ranging from…
- Trial name
- NCT04278599
- Testing
- Oral Zinc supplementation
- Where
- India
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Psoriasis
The Maintenance Effect of Enstilar Foam in Combination With Otezla
This is a single-center, open-label study. Approximately 30 qualified subjects will be enrolled in a study lasting 20 weeks which investigates the effect of Enstilar used in combination with Otezla to treat psoriasis.
- Trial name
- NCT04555707
- Testing
- Apremilast 30mg, calcipotriene and betamethasone dipropionate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Derm Research, PLLC
Rheumatoid Arthritis, Ankylosing Spondylitis
Artificial Intelligence Literacy and E-Health Literacy in Rheumatic Diseases
This study aims to evaluate digital health competencies in individuals with rheumatic and degenerative joint diseases. Specifically, it assesses e-health literacy and artificial intelligence literacy, which refer to individuals'…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis, Knee Osteoarthritis
- Trial name
- NCT07054749
- Where
- Turkey (Türkiye)
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Gulseren Demir Karakilic
Psoriasis
Low-Dose (17.5 mg/Day) Acitretin: Comparable Efficacy Without the Side Effects?
Psoriasis is a chronic skin disorder with a prevalence of approximately 1-3% worldwide. At present, there is no curative therapy available and the clinical course is unpredictable, but in the majority of cases psoriasis is a…
- Trial name
- NCT01228409
- Testing
- Acitretin 17.5 mg/day
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Frankel, Amylynne, M.D.
Autoimmune Diseases, Rheumatoid Arthritis (RA)
Study of S-4321 in Participants With an Autoimmune or Immune-mediated Disease
This is a multi-center, open-label Ph 1b basket study to assess safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), immunogenicity, biomarker response, and preliminary efficacy of multiple doses of S-4321 in…
- Conditions
- Autoimmune Diseases, Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA), Psoriasis (PsO)
- Trial name
- NCT07455578
- Testing
- S-4321
- Where
- 2 sites in Australia
- Volunteers
- 24 people
- Sponsor
- Seismic Therapeutic AU Pty Ltd
Psoriasis
An Outcomes Study to Determine the Reasons Patients on Biologic Therapy Discontinue Treatment and Fail to Follow-up With Their Providers
Patient interviews to evaluate the reason patients discontinue biologic therapy and/or fail to follow up with provider.
- Trial name
- NCT03964168
- Testing
- Biologic Agent
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Psoriasis Treatment Center of Central New Jersey
Arthritis, Psoriatic, Arthritis, Rheumatoid
Effectiveness of Digital Rehabilitation (SIMPLI.REHAB) in Hand Arthritis
This study investigates the effectiveness of SIMPLI.REHAB, a digital tool employed as an interface for administering occupational rehabilitation programs to patients diagnosed with Rheumatoid and Psoriatic Arthritis.
- Conditions
- Arthritis, Psoriatic, Arthritis, Rheumatoid, Deformity, Hand, Limitation, Mobility
- Trial name
- NCT06077890
- Testing
- Digital Rehabilitation, Conventional Rehabilitation
- Where
- Portugal
- Volunteers
- 35 people
- Sponsor
- Centro Hospitalar de Vila Nova de Gaia/Espinho, E.P.E.
Psoriatic Arthritis
TNF and IL23 Blocking Agents Gene Expression Ratios in the Psoriatic Arthritis Synovium_(TIGERS) Study
This study compare the genomics profiles in synovial biopsies obtained prior to, and 24 weeks after a biologic disease modifying anti-rheumatic drugs (DMARDs)(Adalimumab, Ustekinumab, Guselkumab) in patients with active psoriatic…
- Trial name
- TIGERS (NCT04261010)
- Testing
- Global/single cell gene expression profiles obtained from Synovial biopsies
- Where
- 2 sites in Belgium
- Volunteers
- 36 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Oral Mucosal Disease
Clinical Research Core Dental Screening Protocol
This study will screen patients for eligibility in studies sponsored by the Craniofacial Genetics Section (HCGS), the Clinical Research Core (CRC), and other branches located within the National Institute of Dental and…
- Trial name
- NCT00090818
- Where
- United States
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Psoriasis
An AI-Based Erythema Measurement System for Psoriasis Lesions
Psoriasis is a common chronic inflammatory skin disease. Disease severity is commonly assessed using the Psoriasis Area and Severity Index (PASI), in which erythema is graded subjectively on a 0-4 scale.
- Trial name
- NCT07494396
- Testing
- No additional drugs(control Group)
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- Khon Kaen University
Psoriasis
A Study to Evaluate the Efficacy and Safety of LZM012 ( Psoriasis )
This study is a Multicenter, Open-Label, Single-Arm Phase III Clinical Trial to Evaluate the Efficacy and Safety of LZM012 Injection in Patients With Moderate to Severe Plaque Psoriasis.
- Trial name
- NCT07746479
- Testing
- LZM012
- Where
- China
- Volunteers
- 244 people
- Sponsor
- Livzon Pharmaceutical Group Inc.
Palmoplantar Pustulosis
A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in Adults With Palmoplantar Pustulosis
A study to evaluate the efficacy and safety, and pharmacokinetic (PK) profile of multiple doses of imsidolimab (ANB019) in adults with palmoplantar pustulosis (PPP)
- Trial name
- POPLAR (NCT03633396)
- Testing
- Imsidolimab
- Where
- 39 sites in United States, Canada and 2 more
- Volunteers
- 59 people
- Sponsor
- Vanda Pharmaceuticals
Oral Lichen Planus
Comparison of Triamcinolone Acetonide Mucoadhesive Film and Licorice Mucoadhesive Film Effect on Lichen Planus
Introduction :Oral lichen planus (OLP) is one of the most common disorders of the oral cavity which is basically a chronic and inflammated mucocutaneous .There is no cure for OLP currently.
- Trial name
- NCT02453503
- Testing
- Licorice, Triamcinolone Acetonide
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Arthritis, Psoriatic
Investigation of 9 Consecutive Infusions of Remicade for Psoriatic Arthritis in Austria (Study P04264)
This is a prospective, open-label, 1-arm, multicenter observational study to determine the dose and time interval of Remicade (Infliximab) infusions in psoriatic arthritis (PsA).
- Trial name
- NCT00725296
- Testing
- Remicade (Infliximab)
- Volunteers
- 178 people
- Sponsor
- Merck Sharp & Dohme LLC
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