Clinical trials: Skin Diseases, Papulosquamous
Psoriasis, Inflammation
Comparative Effectiveness of Psoriasis Treatments on Systemic Inflammation
This is a prospective longitudinal observational pilot study of psoriasis patients on continuous standard-of-care systemic therapeutics to determine the level of change in established (plasma/serum) and investigative (cellular)…
- Trial name
- NCT02330380
- Testing
- Methotrexate, Ustekinumab, Etanercept
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University Hospitals Cleveland Medical Center
Psoriatic Arthritis
Efficacy of Secukinumab Compared to Adalimumab in Patients With Psoriatic Arthritis
This was a randomized, double-blind, active controlled, multicenter, parallel-group study evaluating secukinumab monotherapy and adalimumab monotherapy in approximately 850 patients with active psoriatic arthritis (PsA) who are…
- Trial name
- EXCEED 1 (NCT02745080)
- Testing
- Secukinumab, Adalimumab
- Where
- 156 sites in United States, Australia and 24 more
- Volunteers
- 853 people
- Sponsor
- Novartis Pharmaceuticals
Psoriasis Vulgaris
Therapeutic Drug Monitoring of Secukinumab in Psoriasis Patients.
Biologics such as secukinumab are currently the most effective treatment option for patients with moderate to severe psoriasis. But they are costly for healthcare systems and still described according to a'one dose fits all'…
- Trial name
- BIOLOPTIM-SEC (NCT04080661)
- Testing
- Venapuncture, Patient questionnaires
- Where
- 7 sites in Belgium
- Volunteers
- 82 people
- Sponsor
- University Hospital, Ghent
Psoriasis
A Nurse-led Individualized Educational Intervention
60 newly referred patients with psoriasis at the Department of Dermatology and Allergy, Herlev and Gentofte Hospital, Denmark will be consecutive included in the study.
- Trial name
- NCT03127462
- Testing
- Nurse-led educational intervention
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Lina R. Khoury
Oral Lichen Planus
Comparison of Triamcinolone Acetonide Mucoadhesive Film and Licorice Mucoadhesive Film Effect on Lichen Planus
Introduction :Oral lichen planus (OLP) is one of the most common disorders of the oral cavity which is basically a chronic and inflammated mucocutaneous .There is no cure for OLP currently.
- Trial name
- NCT02453503
- Testing
- Licorice, Triamcinolone Acetonide
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Psoriasis, Social Isolation
Walk and Talk: Connecting People With Psoriasis
The main aim of this study is to determine the acceptability, representativeness (e.g. age, sex, ethnicity and body mass index) and ideal format of a Walk and Talk intervention for people with psoriasis.
- Trial name
- NCT06726213
- Testing
- Walk and talk
- Where
- United Kingdom
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Arthritis, Psoriatic (PsA), Arthritis, Rheumatoid (RA)
Patient-Reported Outcomes Dashboard With Goal Setting to Support Shared Decision-Making in Inflammatory Arthritis
The goal of this clinical trial is to learn whether showing patient-reported symptoms and personal treatment goals to rheumatology clinicians on a dashboard in the electronic health record improves shared decision-making for…
- Trial name
- NCT07865390
- Testing
- Patient-Reported Outcomes Dashboard With Goal Setting
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Northwestern University
Psoriasis, Inflammation
A Herbal Compound for Psoriasis
The goal of this interventional clinical trial study is to compare ZAX.1400.P03 and placebo in Psoriasis patients. The main question it aims to answer is: Can treatment with ZAX.1400.P03 for 3 weeks improve clinical signs of skin…
- Conditions
- Psoriasis, Inflammation, Skin Diseases
- Trial name
- NCT06301997
- Testing
- ZAX.1400.P03
- Where
- Iran
- Volunteers
- 104 people
- Sponsor
- Fasa University of Medical Sciences
Psoriasis
Efficacy and Safety of Benvitimod Cream in the Retreatment of Mild to Moderate Psoriasis
This is a retreatment, multicenter, randomized, double-blind, placebo-controlled clinical study to evaluate the safety and efficacy of Benvitimod cream, 1% twice daily for the retreatment of mild to moderate stable psoriasis…
- Trial name
- NCT05326659
- Testing
- Benvitimod Cream
- Where
- China
- Volunteers
- 390 people
- Sponsor
- Peking University People's Hospital
Psoriasis
ACT-128800 in Patients With Moderate to Severe Chronic Plaque Psoriasis
This study will assess the efficacy, safety and tolerability of two doses of ACT 128800 in patients with moderate-to-severe chronic plaque psoriasis.
- Trial name
- NCT01208090
- Testing
- ACT-128800
- Where
- 67 sites in Austria, Belgium and 15 more
- Volunteers
- 326 people
- Sponsor
- Actelion
Sneddon-Wilkinson, Acrodermatitis Continua of Hallopeau
Anakinra for Inflammatory Pustular Skin Diseases
Background: Inflammatory pustular skin diseases are a type of autoinflammatory disease in which the immune system attacks the bodys tissues.
- Conditions
- Sneddon-Wilkinson, Acrodermatitis Continua of Hallopeau, Pustular Psoriasis, Palmoplantar Pustulosis
- Trial name
- NCT01794117
- Testing
- Anakinra
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Psoriasis
Luma Light System Proof of Concept Study in Subjects With Mild to Moderate Psoriasis
This is a proof of concept, investigator blinded study to evaluate the efficacy and safety of a novel combination of a home narrow band ultraviolet B (NBUVB) lamp with an occlusive dressing in adult subjects with mild to moderate…
- Trial name
- NCT02447068
- Testing
- Luma Light System, Luma Light, Occlusive Dressing
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Illumicure Inc
Psoriasis
A Phase 2 Study of Efficacy and Safety of AK111 in Subjects With Moderate-to-Severe Psoriasis
This is a randomized, double-blind, placebo-controlled, multi-center Phase II clinical study to evaluate the efficacy and safety of AK111 for the treatment of moderate to severe plaque psoriasis.
- Trial name
- NCT05096364
- Where
- 13 sites in China
- Volunteers
- 251 people
- Sponsor
- Akeso
Psoriasis
An Ascending Multiple Dose Study With VTP-43742 in Healthy Volunteers and Psoriatic Patients
This is a two-part, randomized, double-blind, placebo-controlled study in which VTP-43742 will be administered to normal healthy volunteers (NHV) and to moderate to severe psoriatic patients, both in sequential ascending dose…
- Trial name
- NCT02555709
- Testing
- VTP-43742
- Where
- 14 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Vitae Pharmaceuticals Inc., an Allergan affiliate
Rheumatoid Arthritis, Ankylosing Spondylitis
A Study to Evaluate the Safety of Remsima® SC in the Treatment of RA, AS, PsA and Ps
This is an observational, prospective cohort study to evaluate the safety of Remsima® SC in the treatment of RA, AS, PsA and Ps.
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis, Psoriasis
- Trial name
- NCT05866614
- Testing
- Remsima IV, Remsima SC
- Where
- France
- Volunteers
- 881 people
- Sponsor
- Celltrion
Psoriasis (PsO), Vitiligo Vulgaris
Evaluation of Stigma Toward Patients With Alopecia Areata, Atopic Dermatitis, Vitiligo, and Psoriasis
Primary objective: The primary objective is to evaluate in the general population the difference between emotional reactions associated with facial involvement by four major dermatologic diseases: psoriasis, atopic dermatitis…
- Conditions
- Psoriasis (PsO), Vitiligo Vulgaris, Atopic Dermatitis, Areata Alopecia
- Trial name
- STIGMADERM (NCT06801821)
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Psoriasis Vulgaris, Active Psoriatic Arthritis
Effect of Bimekizumab in Patients With Psoriasis Vulgaris and Active Psoriatic Arthritis
This is an open-label study to evaluate the effects of bimekizumab in patients with psoriasis vulgaris and who also have active psoriatic arthritis (PsA).
- Trial name
- NCT05499416
- Testing
- Bimekizumab
- Sponsor
- Innovaderm Research Inc.
Moderate to Severe Psoriasis
Clinical Effectiveness and Impact on Health-related Quality of Life in Peruvian Patients With Psoriasis After 16 Weeks of Adalimumab Therapy
Adalimumab has recently been authorized for active psoriasis in Peru and local experience is very low. The aim of this study is to obtain Peruvian data of clinical effectiveness and impact on health-related quality of life with…
- Trial name
- NCT01156532
- Where
- 3 sites in Peru
- Volunteers
- 30 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Psoriatic Arthritis
Efficacy and Safety of HS-10374 Compared to Placebo in Adults With Active Psoriatic Arthritis
This study has been designed to explore the clinical efficacy and safety of HS-10374 in the treatment of active psoriatic arthritis.
- Trial name
- NCT06176508
- Testing
- HS-10374, Tofacitinib 5Mg Tab,Oral
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Hansoh BioMedical R&D Company
Atopic Dermatitis, Psoriasis
The Role of Bacterial Toxins in Human Skin Disease
Atopic dermatitis and psoriasis are two skin diseases often associated with bacterial infections and inflammation. Studies indicate that skin cells from these patients may have some changes that make these patients more…
- Trial name
- NCT02910791
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Jewish Health
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