Clinical trials: Skin Diseases, Papulosquamous
Rheumatoid Arthritis, Psoriatic Arthritis
GOTHA - The Early Arthritis and Psoriasis Study of Region Västra Götaland, Sweden
GÖTHA- The early arthritis and psoriasis study of Region Västra Götaland, Sweden - is a longitudinal observational study, which will prospectively and in parallel follow patients with newly diagnosed rheumatoid arthritis (RA…
- Conditions
- Rheumatoid Arthritis, Psoriatic Arthritis, Arthritis, Psoriasis
- Trial name
- GOTHA (NCT04190758)
- Testing
- Care as usual
- Where
- Sweden
- Volunteers
- 5,100 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Psoriasis
Combination of Sotyktu and Enstilar for Plaque Psoriasis
combination deucravacitinib and enstilar foam
- Trial name
- NCT06329258
- Testing
- Enstilar, Deucravacitinib
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Psoriasis Treatment Center of Central New Jersey
Psoriasis
Prediction Model for Osteopenia in Patients With Psoriasis
This study aims to develop a clinical prediction model for osteopenia in patients with psoriasis. By retrospectively analyzing demographic, laboratory, and lifestyle variables, the investigators will identify risk factors…
- Trial name
- NCT07112755
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chongli Yu
Psoriasis
A Study to Evaluate Pharmacokinetic (PK), Safety and Tolerability of GSK2894512 in Healthy Adult Subjects
GSK2894512 (trans-isomer) is a fully synthetic, non-steroidal anti-inflammatory agent. This study is being conducted to evaluate the PK, safety and tolerability of GSK2894512 cream, 1 percent administered topically to healthy…
- Trial name
- NCT03201978
- Testing
- GSK2894512 1% CREAM, GSK2894512 MATCHING VEHICLE CREAM
- Volunteers
- healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Psoriasis (PsO)
A Drug-Drug Interaction Study Between HS-10374 Tablets and Drospirenone and Ethinyl Estradiol Tablets(Yasmin®)
This trial is a single-center, open-label, fixed-sequence, self-controlled clinical study to evaluate Drug-Drug Interaction Between HS-10374 Tablets and Drospirenone and Ethinyl Estradiol Tablets (Yasmin®)
- Trial name
- NCT07181343
- Testing
- HS-10374 tablets, Drospirenone and Ethinyl Estradiol tablets
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hansoh BioMedical R&D Company
Psoriasis
Effective Study of Live Attenuated Varicella Vaccine to Treat Severe Resistant Psoriasis
Immunotherapy was reported in the treatment of psoriasis. Treatment of resistant psoriasis may be difficult and cyclosporine can induce some remission.
- Trial name
- NCT01356004
- Testing
- live attenuated chicken pox vaccine, saline, efficacy
- Where
- Egypt
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Cairo University
Psoriasis
An Efficacy and Safety Study of LYC-30937-EC in Subjects With Moderate Chronic Plaque-type Psoriasis
The objective of this Phase 2 trial is to determine the efficacy and safety of LYC-30937-EC in patients with moderate plaque-type psoriasis.
- Trial name
- NCT02872285
- Testing
- Drug: LYC-30937-EC
- Where
- 7 sites in United States
- Volunteers
- 33 people
- Sponsor
- Lycera Corp.
Vulvar Lichen Sclerosus, Vulvar Atrophy
Efficacy of Collagendep in Reducing Vulvar Dryness in Patients With Lichen Sclerosus Treated With Fat Grafting
This randomized, interventional study evaluates the efficacy of Collagendep Pink Beauty, an oral nutritional supplement, in reducing vulvar dryness in women with Genital Lichen Sclerosus (VLS) who are undergoing fat grafting…
- Trial name
- Collagendep (NCT07450625)
- Testing
- Autologous Fat Grafting (Lipofilling), Collagendep Pink Beauty
- Volunteers
- 40 people
- Sponsor
- San Gallicano Dermatological Institute IRCCS
Psoriasis
A Comparison Between Clobetasol Propionate 0.05% (Clobex®) Spray and Clobetasol Propionate 0.05% (Olux®) Foam
The primary objective of this study is to evaluate the efficacy and safety of clobetasol propionate 0.05% (Clobex®) spray compared to clobetasol propionate 0.05% (Olux®) foam.
- Trial name
- NCT00436540
- Testing
- Clobetasol Propionate 0.05% Spray, Clobetasol Propionate 0.05% Foam
- Where
- 2 sites in United States
- Volunteers
- 78 people
- Sponsor
- Galderma R&D
Psoriasis
An Ascending Multiple Dose Study With VTP-43742 in Healthy Volunteers
This is Part 1 of a two-part, randomized, double-blind, placebo-controlled study in which VTP-43742 was administered to participants; Part 1 in healthy volunteers and Part 2 in psoriatic participants.
- Trial name
- NCT03724292
- Testing
- VTP-43742
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Vitae Pharmaceuticals Inc., an Allergan affiliate
Psoriasis
Evaluation of the Effect of Narrowband UVB Versus Methotrexate on Serum TWEAK Level in Psoriasis
The aim of the study is to evaluate the effect of NB-UVB versus MTX on serum TWEAK level in psoriatic patients.
- Trial name
- NCT04811911
- Testing
- Narrowband ultraviolet B, Methotrexate
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aswan University Hospital
Pustulosis of Palms and Soles
Efficacy Study of TEPSO® Socks in Improving Palmoplantar Pustulosis
The purpose of this study is to evaluate the efficacy of a special sock, manufactured using TEPSO®, compared to a normal cotton sock in the prognosis of symmetrical palmoplantar pustulosis present for at least one year.
- Trial name
- NCT01197989
- Testing
- TEPSO cloth, Standard cloth
- Where
- 3 sites in Italy
- Volunteers
- 17 people
- Sponsor
- Lenzi Egisto S.P.A.
Moderate to Severe Nail Psoriasis
Study of Safety, Tolerability, and Efficacy of Secukinumab in Subjects With Moderate to Severe Nail Psoriasis
This purpose of this study was to demonstrate the efficacy of secukinumab versus placebo on nail psoriasis and to assess long-term efficacy, safety and tolerability of secukinumab.
- Trial name
- TRANSFIGURE (NCT01807520)
- Testing
- Secukinumab
- Where
- 40 sites in United States, Australia and 7 more
- Volunteers
- 198 people
- Sponsor
- Novartis Pharmaceuticals
Arthritis, Psoriatic
A Study of the Safety and Efficacy of Ustekinumab in Patients With Psoriatic Arthritis With and Without Prior Exposure to Anti-TNF Agents
The purpose of this study is to evaluate the efficacy (improvement of signs and symptoms) and safety of ustekinumab in patients with psoriatic arthritis.
- Trial name
- NCT01077362
- Testing
- ustekinumab 45 mg, ustekinumab 90 mg
- Where
- 80 sites in United States, Austria and 8 more
- Volunteers
- 312 people
- Sponsor
- Janssen Research & Development, LLC
Severe Seborrheic Dermatitis
Tacrolimus Ointment Interest (PROTOPIC ®) in the Maintenance Treatment of Severe Seborrheic Dermatitis
Seborrheic dermatitis is a chronic inflammatory dermatological disease, evolving by relapses, affecting mainly the face and scalp.
- Trial name
- Disease (NCT02004860)
- Testing
- Protopic (R), Mycoster (R)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Rouen
Psoriasis
A Study Assessing the PK, PD, Safety, and Tolerability of SB414 in Psoriasis
The objectives of this study are to assess the pharmacokinetics, pharmacodynamics, safety, and tolerability of SB414 in subjects with mild to moderate plaque psoriasis.
- Trial name
- NCT03445013
- Testing
- SB414 6%, Vehicle
- Where
- 4 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Novan, Inc.
Oral Lichen Planus
The Effect of Topical Curcumin Versus Topical Corticosteroid on Management of Oral Lichen Planus Patients
Introduce a new anti-inflammatory and antioxidant paste preparation (curcumin paste) in the management of Oral lichen planus. Assess the efficacy of this preparation on pain, clinical parameter and the level of IL-33 in saliva.
- Trial name
- NCT03877679
- Testing
- Triamcinolone, Turmeric paste
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Psoriatic Arthritis, Obesity
Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Psoriatic Arthritis and Obesity or Overweight
The main purpose of this study is to demonstrate that when participants with psoriatic arthritis and obesity or overweight in the presence of at least 1 weight-related comorbid condition receive ixekizumab and tirzepatide…
- Trial name
- TOGETHER-PsA (NCT06588296)
- Testing
- Ixekizumab, Tirzepatide
- Where
- 86 sites in United States, Puerto Rico
- Volunteers
- 279 people
- Sponsor
- Eli Lilly and Company
Rheumatoid Arthritis, Spondyloarthritis
Information and Acceptability of Biosimilars
Patients with rheumatoid arthritis or spondyloarthritis, currently treated or about to be started with anti-TNF original drug adalimumab or etanercept will be included and randomized to either " information leaflet only " or "…
- Conditions
- Rheumatoid Arthritis, Spondyloarthritis, Psoriatic Arthritis
- Trial name
- BIOSIMINFO (NCT04321291)
- Testing
- Generic information leaflet, Individual information by nurse on biosimilars
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Montpellier
Psoriasis
Randomized Double-Blind Placebo-Controlled Trial Using Recombinant Human Interleukin-10 for Moderate-to-Severe Psoriasis
Several studies have documented an essential role for interleukin-10 (IL-10) in preventing prolonged and exaggerated immune responses to antigens and irritants.
- Trial name
- NCT00001797
- Testing
- Recombinant human interleukin-10
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- National Cancer Institute (NCI)
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