Clinical trials: Skin Diseases, Papulosquamous
Psoriatic Arthritis
Disease Impact and Its Correlation With Disease Activity in Psoriatic Arthritis
Psoriatic arthritis (PsA) is a chronic inflammatory musculoskeletal disorder that causes joint pain, stiffness, skin lesions, and functional disability, significantly affecting patients' quality of life.
- Trial name
- NCT07793773
- Volunteers
- 80 people
- Sponsor
- Assiut University
Psoriasis
A Study of Topical Indigo Naturalis Treatment in Patients With Mild to Moderate Plaque-type Psoriasis
Psoriasis is a common, chronic skin disease for which only remissive, as opposed to curative, treatments are available. Traditional Chinese medicine is one of the most frequently chosen alternative therapies in China and Taiwan…
- Trial name
- NCT01901705
- Testing
- Indigo naturalis ointment
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- China Medical University Hospital
Plaque Psoriasis
NB-UVB Phototherapy With and Without Topical LCD Treatment: a Bilateral Pilot Study
The purpose of this study is to determine if combining a daily at-home regimen using an LCD Solution with a 3 times weekly outpatient narrowband UVB phototherapy regimen could be a safe, effective, rapid, and, convenient…
- Trial name
- NCT00708851
- Testing
- LCD Solution with NB-UVB Phototherapy, NB-UVB Light Device (311-315 nm)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- NeoStrata Company, Inc.
Psoriasis
Study of Efficacy and Safety of HB0017 in Patients With Moderate to Severe Plaque Psoriasis
This is a multicenter, randomized, double-blind, placebo-controlled, phase III clinical study which is designed to determine the efficacy, safety, immunogenicity and pharmacokinetics, and pharmacodynamics of HB0017 Injection in…
- Trial name
- NCT06477237
- Testing
- HB0017 Q4W, HB0017 Q8W
- Where
- 44 sites in China
- Volunteers
- 408 people
- Sponsor
- Huabo Biopharm Co., Ltd.
Psoriatic Arthritis
A Phase 2 Study to Investigate the Safety, Tolerability and Efficacy of ABT-122 in Subjects With Active Psoriatic Arthritis (PsA) Who Have an Inadequate Response to Methotrexate (MTX)
This study is a Phase 2 randomized, double-blind, double-dummy, active- and placebo-controlled, parallel-group study designed to assess the safety, tolerability, efficacy, pharmacokinetics and immunogenicity of multiple doses of…
- Trial name
- NCT02349451
- Testing
- adalimumab, ABT-122
- Volunteers
- 240 people
- Sponsor
- AbbVie
Psoriasis
Open Label, Safety and Efficacy Study of Topical Investigational Drug to Treat Patients With Psoriasis
This will be an open label study of ruxolitinib topical cream applied to 2 - 20% BSA in patients with active, stable plaque psoriasis.
- Trial name
- NCT00617994
- Testing
- Ruxolitinib
- Where
- 4 sites in United States
- Volunteers
- 25 people
- Sponsor
- Incyte Corporation
Psoriasis, Arthritis
Safety and Efficacy of BFH772 in Psoriasis Patients
This study will determine the efficacy of topical BFH772 in psoriasis patients and the safety after multiple dosing.
- Trial name
- NCT00987870
- Testing
- BFH772, calcipotriol/betamethasone
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Novartis Pharmaceuticals
Oral Lichen Planus
Tacrolimus Ointment in Oral Lichen Planus
The purpose of this study is to compare the effectiveness of topical tacrolimus, triamcinolone and placebo in alleviating signs and symptoms of oral lichen planus (OLP).
- Trial name
- NCT01544842
- Testing
- 0.1 % tacrolimus ointment, 0.1 % triamcinolone paste, Orabase paste
- Where
- 2 sites in Finland
- Volunteers
- 28 people
- Sponsor
- University of Oulu
Oral Lichen Planus
Efficacy of Coconut Gel Compared to Corticosteroid Gel in the Management of Oral Lichen Planus
In oral lichen planus ,Tumor necrosis factor-alpha (TNF-α) has a role in the progression of the disease, enhancing CD8+ cytotoxic T cells and plays a role in the malignant transformation of the lesion.
- Trial name
- NCT07100145
- Testing
- Coconut oil, Triamcinolone Acetonide
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Ain Shams University
Psoriatic Arthritis (PsA)
Deucravacitinib-TNFi Combination Therapy for Difficult-to-Control Psoriatic Disease
The purpose of this research study is to determine the effectiveness of adding deucravacitinib to the participant's current Psoriatic Arthritis (PsA) treatment to see if it improves their symptoms and quality of life.
- Trial name
- COMBo (NCT07280702)
- Testing
- Deucravacitinib
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Texas Southwestern Medical Center
Vulvar Disease, Lichen Sclerosus
Vulvar Mucosal Specialty Clinic Chart Review
This study aims to develop a clinical database of patients presenting with vulvar complaints in order to comprehensively assess the presentation and current trends in management of vulvar disease.
- Conditions
- Vulvar Disease, Lichen Sclerosus, Lichen Planus, Vulvodynia
- Trial name
- NCT02881229
- Where
- United States
- Volunteers
- 719 people
- Sponsor
- Northwestern University
Moderate to Severe Plaque Psoriasis
Clinical Trial to Evaluate the Safety, Tolerability and Efficacy of CT303 in Patients With Psoriasis
Investigate the Safety, Tolerability, Efficacy and pharmacodynamics properties of CT303 in patients with moderate to severe plaque psoriasis
- Trial name
- NCT05258331
- Testing
- CT303
- Where
- 3 sites in South Korea
- Volunteers
- 24 people
- Sponsor
- GC Cell Corporation
Lichen Planus
Use of Etanercept in the Treatment of Moderate to Severe Lichen Planus
The purpose is to assess the response of subjects to etanercept (as compared to placebo) in treating the physical signs of mucosal and cutaneous lichen planus.
- Trial name
- NCT00285779
- Testing
- Etanercept
- Where
- 12 sites in United States
- Volunteers
- 27 people
- Sponsor
- Stanford University
Psoriasis
A Study of the Real-life Management of Psoriasis Patients Treated With Otezla® (Apremilast) in Belgium
OTELO is a national (Belgium), multicentre, prospective, non-interventional, post-marketing study. The study will include a representative sample of approximately 250 patients with moderate-to-severe plaque psoriasis for whom the…
- Trial name
- OTELO (NCT03097003)
- Testing
- Apremilast
- Where
- 22 sites in Belgium
- Volunteers
- 124 people
- Sponsor
- Amgen
Psoriasis
Single Rising Dose Study of BI 655066 in Patients With Moderate and Severe Psoriasis
Safety, tolerability and efficacy of BI 655066 in male and female patients with moderate to severe psoriasis.
- Trial name
- NCT01577550
- Testing
- BI 655066 (very high i.v. dose), BI 655066 (high s.c. dose), BI 655066 (low i.v. dose)
- Where
- 9 sites in United States, Germany and 1 more
- Volunteers
- 39 people
- Sponsor
- AbbVie
Psoriasis
Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Effects of AMG 811 in Subjects With Psoriasis
The purpose of this study is to assess the safety, tolerability, immunogenicity, and clinical effects of AMG 811 following single subcutaneous dose administration in subjects with moderate to severe psoriasis.
- Trial name
- NCT01510951
- Where
- 4 sites in Australia, New Zealand
- Volunteers
- 9 people
- Sponsor
- Amgen
Psoriasis
A Study Evaluating The Efficacy And Safety Of CP-690,550 In Asian Subjects With Moderate To Severe Plaque Psoriasis
The primary objective of this study is to compare the efficacy of CP-690,550 (5 mg BID and 10 mg BID) versus placebo for the reduction in severity of plaque psoriasis after 16 weeks of treatment in Asian subjects with moderate to…
- Trial name
- NCT01815424
- Testing
- CP-690,550
- Where
- 24 sites in China, South Korea and 1 more
- Volunteers
- 266 people
- Sponsor
- Pfizer
Psoriasis, Vascular Inflammation
Effect of Adalimumab on Vascular Inflammation in Patients With Moderate to Severe Plaque Psoriasis
This study is to determine the effect of adalimumab on inflammation of blood vessels that could lead to heart attack in patients with psoriasis.
- Conditions
- Psoriasis, Vascular Inflammation, Coronary Atherosclerosis
- Trial name
- NCT00940862
- Testing
- adalimumab, UVB Phototherapy, Topical treatment
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Innovaderm Research Inc.
Psoriasis
The Disease Severity In Patients With Psoriasis
This observational study aims to evaluate new markers to predict disease activity in psoriasis. The main question is SGOT, SGPT, GGT, hs-CRP, and apo B related to disease severity in psoriasis.
- Trial name
- NCT05943405
- Where
- Indonesia
- Volunteers
- 33 people
- Sponsor
- Universitas Sebelas Maret
Psoriatic Arthritis
Treatment Goals in Psoriatic Arthritis
The PaGoPsA study objective is to ascertain if guideline-based psoriatic arthritis clinical care achieves individual patient goals as articulated by patients, and to identify predictors of achieving individual patient goals from…
- Trial name
- PaGoPsA (NCT03620188)
- Testing
- Standard of care
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Johns Hopkins University
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