Clinical trials: Skin Infection
Warts, Human Papilloma Virus
Candida Antigen and Bivalent HPV Vaccine in the Treatment of Multiple Warts
To follow up the efficacy and safety of Candida antigen, bivalent HPV vaccine in treatment of common warts either mono or combined intralesional therapy
- Trial name
- NCT05291845
- Testing
- Candida antigen vaccine, Bivalent HPV vaccine
- Where
- Egypt
- Volunteers
- 162 people
- Sponsor
- Zagazig University
Onchocerciasis, Loiasis
Development of a New Rapid Diagnostic Test to Support Onchocerciasis Elimination
Onchocerciasis, also known as river blindness, is one of the disease targeted for elimination by the World Health Organization (WHO) in the group of Neglected Tropical Diseases.
- Conditions
- Onchocerciasis, Loiasis, Mansonelliasis, Healthy Volunteers
- Trial name
- Obi1 (NCT06350851)
- Testing
- Biological samples collection (blood drawing + feces)
- Where
- Cameroon
- Volunteers
- 1,128 people, healthy volunteers welcome
- Sponsor
- Bioaster
Invasive Fungal Infections
Endemic Mycoses Treatment With SUBA-itraconazole vs Itraconazole
This is a prospective, multi-center, randomized, open-label parallel arm study involving patients with proven or probable invasive endemic fungal infection to ascertain the pharmacokinetics, safety, efficacy, tolerability and…
- Trial name
- MSG15 (NCT03572049)
- Testing
- SUBA itraconazole, Conventional itraconazole
- Where
- 12 sites in United States, Panama
- Volunteers
- 88 people
- Sponsor
- University of Alabama at Birmingham
Impetigo
Study to Evaluate the Safety and Efficacy of Topical Minocycline FXFM244 in Impetigo Patients
Impetigo is a common, highly infectious skin disease caused by bacterial infection and characterized by crusting skin lesions. It is most common in children, particularly children in unhealthy living conditions.
- Trial name
- NCT01171326
- Testing
- Topical Minocycline Foam FXFM244
- Where
- Israel
- Volunteers
- 32 people
- Sponsor
- Vyne Therapeutics Inc.
Rheumatic Arthritis
Exercise Training and Knee Joint Proprioception in Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic disorder that affects 0.5% to 1% of adults and is the result of an autoimmune attack against joint tissues.
- Trial name
- NCT06887725
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people
- Sponsor
- Aysima Barlak
Impetigo, Folliculitis
Twice Daily Altabax Application for the Treatment of Uncomplicated Soft Tissue Infection
The purpose of this study is to document the clinical and bacteriological efficacy of retapamulin in the treatment of subjects with bacterial infections, including impetigo, folliculitis, and minor soft tissue infections…
- Conditions
- Impetigo, Folliculitis, Secondarily Infected Eczema, Minor Soft Tissue Infections
- Trial name
- NCT01126268
- Testing
- Retapamulin (Altabax)
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- The University of Texas Health Science Center, Houston
Arthritis, Rheumatoid, Spondyloarthritis
Pain Catastrophizing and Routine Assessment of Patient Index Data 3(RAPID3) in Ten Categories of Rheumatology Outpatients
Fulfilling by all patients consequently seen by 6 rheumatologists in a same outpatient rheumatology clinic (in at least one month period) of a set of 6 questionnaires, including RAPID3 and pain catastrophizing scales.
- Conditions
- Arthritis, Rheumatoid, Spondyloarthritis, Inflammatory Rheumatisms, Systemic Disorders
- Trial name
- NCT03306784
- Testing
- questionnaires
- Where
- France
- Volunteers
- 572 people
- Sponsor
- Nantes University Hospital
Cellulitis
Effect of Teledermatology on Length of Hospital Admission, Length of Stay, 30 Day Readmission Rate, and Antibiotic Use in Patients Presenting With Cellulitis vs Pseudocellulitis in an Academic ED Setting
The effect of teledermatology on length of hospital admission, length of stay, 30 day readmission rate, and antibiotic use in patients presenting with cellulitis vs pseudocellulitis in an academic emergency department setting.
- Trial name
- NCT03036358
- Testing
- teledermatology consult, Routine Care
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Skin Structures and Soft Tissue Infections, Wound Infection
The PLUS Study: Comparison of VicrylPlus® Versus Vicryl® for Repair of Perineal Tears
INTRODUCTION It is estimated that over 80% of women who give vaginal birth will sustain some form of perineal tear and of these 60-70% will require suturing.
- Trial name
- NCT02863874
- Testing
- VicrylPlus®, Vicryl®
- Where
- Sweden
- Volunteers
- 1,890 people
- Sponsor
- Region Skane
HIV Infections, Psoriasis
Treatment of Psoriasis Using Acitretin in HIV-Positive Patients
To determine the efficacy of acitretin in the treatment of psoriasis in HIV/AIDS patients. Etretinate, a retinoid, has proven successful in the treatment of HIV-infected patients with psoriasis, but it has an elimination…
- Trial name
- NCT00002143
- Testing
- Acitretin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hoffmann-La Roche
Head Lice Infestation, Pediculosis Capitis
Comparative Head Lice Therapy With Dimet 5® vs. Hedrin® Once
Randomized, investigator-blinded, controlled, multicenter comparative study on the treatment of acute head lice infestation in children with 2 dimeticone preparations with different application times and compositions: Dimet 5®…
- Conditions
- Head Lice Infestation, Pediculosis Capitis, Lice
- Trial name
- VEKODIH (NCT04878276)
- Testing
- Dimet 5
- Where
- 26 sites in Germany
- Volunteers
- 240 people
- Sponsor
- Infectopharm Arzneimittel GmbH
Herpes
A Two Arm, Multi-Site Clinical Evaluation of the ARIES HSV 1&2 Assay in Symptomatic Patients
The ARIES HSV 1\&2 Assay is a PCR based test for the direct detection and typing of herpes simplex virus (HSV 1 \& 2) DNA. The objective is to establish the diagnostic accuracy of ARIES HSV-1\&2 Assay.
- Trial name
- NCT02092233
- Where
- 3 sites in United States
- Volunteers
- 1,963 people
- Sponsor
- Luminex Corporation
Chronic Infectious Disease, Chronic Skin Disease
Relationships Among Inflammation, Physical and Mental Health in Subjects With Chronic Inflammatory Physical Diseases.
The prevalence of common mental disorders is high in patients with chronic inflammatory physical diseases(e.g., autoimmune or infectious diseases).
- Conditions
- Chronic Infectious Disease, Chronic Skin Disease, Mental Disorders, Psoriasis
- Trial name
- InflaMent (NCT05125458)
- Where
- Italy
- Volunteers
- 93 people
- Sponsor
- University of Campania Luigi Vanvitelli
Leishmaniasis, Cutaneous
Intralesional Voriconazole, or Intralesional Cryotherapy, or Oral Doxycycline in the Treatment of Cutaneous Leishmaniasis
Leishmaniasis is a vector-borne disease caused by obligate, intracellular protozoa of the genus Leishmania and transmitted by phlebotomine sandflies.
- Trial name
- NCT05708625
- Testing
- Intralesional Sodium stibogluconate, Intralesional Cryotherapy, Intralesional Voriconazole
- Where
- Libya
- Volunteers
- 136 people
- Sponsor
- Zagazig University
Latent Tuberculosis Infection, Tuberculosis
Prospective Comparison of the Tuberculin Skin Test and Interferon-Gamma Release Assays in Diagnosing Infection With Mycobacterium Tuberculosis and in Predicting Progression to Tuberculosis
This is a prospective cohort study of persons tested for latent tuberculosis infection at either high risk for exposure to Mycobacterium tuberculosis or high risk for progression to tuberculosis disease.
- Trial name
- NCT01622140
- Where
- 10 sites in United States
- Volunteers
- 21,334 people
- Sponsor
- Centers for Disease Control and Prevention
Hidradenitis Suppurativa
Pilot Study on Botulinum Toxin B as Treatment for Hidradenitis Suppurativa
Randomized double blind placebo controlled pilot study/proof of concept-study to see if intradermal injection with Botulinum toxin B is an effective treatment of Hidradenitis suppurativa
- Trial name
- NCT03103074
- Testing
- Botulinum B Toxin
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- University Hospital of North Norway
Onychomycosis
Absorption and Systemic Study of AN2690 in Patients With Moderate to Severe Onychomycosis (ADME II)
The purpose of the study is to determine the absorption and systemic pharmacokinetics of AN2690 following daily application to all ten (10) toenails for 28 days.
- Trial name
- NCT00679601
- Testing
- AN2690
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Pfizer
HIV Infection, Lipodystrophy
Lopinavir/r Monotherapy Versus Abacavir/Lamivudine and Lopinavir/r for Limb Fat Recovery in Persons With Lipoatrophy
The aim of this study is to evaluate the efficacy for the recovery of peripheral fat of lopinavir/ritonavir in monotherapy versus abacavir/lamivudine and lopinavir/ritonavir in subjects who developed lipoatrophy while receiving…
- Conditions
- HIV Infection, Lipodystrophy, HIV Infections
- Trial name
- KRETA (NCT00865007)
- Testing
- Monotherapy (Lopinavir/ritonavir), Monotherapy (Lopinavir/ritonavir) + ABC/3TC
- Where
- 11 sites in Spain
- Volunteers
- 88 people
- Sponsor
- Fundacion SEIMC-GESIDA
Non-Small Cell Lung Cancer, Small Cell Lung Cancer
QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors
QUILT-3.055 is a Phase 2b, open-label, multicohort study investigating combination immunotherapies in patients with advanced solid tumors who have previously been treated with PD-1/PD-L1 checkpoint inhibitors.
- Conditions
- Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Urothelial Carcinoma, Head and Neck Squamous Cell Carcinoma
- Trial name
- NCT03228667
- Testing
- N-803 + Pembrolizumab, N-803 + Nivolumab, N-803 + Atezolizumab
- Where
- 35 sites in United States
- Volunteers
- 40 people
- Sponsor
- ImmunityBio, Inc.
Soft Tissue Infections, Mediastinitis
Delafloxacin Plasma and Tissue Concentration in Patients With Skin, Soft Tissue, and Bone and Joint Infections.
The goal of this observational study is to measure how well the antibiotic delafloxacin penetrates into the blood and various body tissues in adult patients over 18 years old.
- Conditions
- Soft Tissue Infections, Mediastinitis, Osteomyelitis/Septic Arthritis, Prosthetic Joint Infection
- Trial name
- DELA-PLAT (NCT07426471)
- Testing
- delafloxacin
- Volunteers
- 20 people
- Sponsor
- IRCCS San Raffaele