Clinical trials: Skin Infection
Skin Diseases, Bacterial
A Study of the Safety and Effectiveness of Levofloxacin Compared to Ticarcillin/Clavulanate Alone or Followed by Amoxicillin/Clavulanate in the Treatment of Complicated Skin Infections
The purpose of this study is to compare the safety and effectiveness of levofloxacin (an antibiotic) with ticarcillin/clavulanate alone or followed by amoxicillin/clavulanate in the treatment of complicated skin infections.
- Trial name
- NCT00249197
- Testing
- levofloxacin
- Volunteers
- 413 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Cesarean Wound Disruption, Cesarean Section; Infection
Delayed Primary Closure of Skin in Emergency Caesarean Section
Pregnant mothers requiring emergency cs with history of ruptured membranes would be allocated randomly into two groups in an aim to study the comparative outcome of different methods of skin closure namely primary and delayed…
- Trial name
- NCT04587960
- Testing
- Delayed primary closure of skin incision in Caesarean section in experimental group, Primary closure of skin incision in Caesarean section in active comparator group
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Dr.Jhuma Biswas
Wound Infection, Surgical
Clinical Outcome in View of Surgical Site Infection (SSI) With Antibacterial Skin Sutures
Background: Poor wound healing and the development of surgical site infection (SSI) continue to occur and remain a significant cause of disability among operated patients.
- Trial name
- NCT01540279
- Where
- Switzerland
- Volunteers
- 52 people
- Sponsor
- University Hospital, Basel, Switzerland
Zoster; Herpes, Trigeminal Neuralgia (Etiology)
Esketamine Combined Pulsed Radiofrequency for Acute/Subacute Zoster-associated Trigeminal Neuralgia
To assess the 1-month effects and safety of esketamine combined PRF and standardized treatment to relieve pain in patients with acute/subacute zoster-related trigeminal neuralgia(ZRTN).
- Trial name
- NCT06890897
- Testing
- Esketamine group, PRF group
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Beijing Tiantan Hospital
Histoplasmosis, Sporotrichosis
Phase II Pilot Study of Fluconazole for Histoplasmosis, Blastomycosis, and Sporotrichosis
OBJECTIVES: I. Identify a preferred oral fluconazole dose regimen for patients with non-acute histoplasmosis or blastomycosis, or ulcerocutaneous or deep sporotrichosis. II.
- Conditions
- Histoplasmosis, Sporotrichosis, Blastomycosis
- Trial name
- NCT00004808
- Testing
- fluconazole
- Volunteers
- 78 people
- Sponsor
- National Center for Research Resources (NCRR)
Streptococcus Group A
Streptococcal Infections in Fiji - Prevalence of Group A Streptococcal Pyoderma and Scabies in Infants in Fiji
Group A streptococcus (GAS) is a bacteria that causes many different sicknesses in children and adults. This study will look at the number of cases of pyoderma (bacterial skin infection) and scabies (skin mites that cause…
- Trial name
- NCT00436891
- Where
- Fiji
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Herpes
A Phase I Clinical Trial of Recombinant Herpes Zoster Vaccine (CHO Cell)
To evaluate the safety and tolerability of different dosages of recombinant zoster vaccine (CHO cell) when administered to adults aged 40 years and older.
- Trial name
- NCT07633197
- Testing
- Recombinant Herpes Zoster Vaccine
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Changchun BCHT Biotechnology Co.
Hidradenitis Suppurativa
An Alternative Dose Interval Study in Participants With Hidradenitis Suppurativa Receiving Brodalumab
Phase 0 Study of an alternative dosing interval of Brodalumab in patients with moderate to severe Hidradenitis Suppurativa to identify biomarkers of disease activity and clinical response.
- Trial name
- NCT04249713
- Testing
- Brodalumab
- Where
- United States
- Sponsor
- Rockefeller University
Onchocerciasis
Study to Assess Adverse Events, Change in Disease Activity and How Oral ABBV-4083 Capsules When Given Alone or In Combination With Albendazole Capsules Moves in The Body of Adult Participants With Onchocerca Volvulus Infection
Onchocerciasis is a major public health problem in affected countries that causes disease-induced disability, and overall loss of economic productivity.
- Trial name
- NCT04913610
- Testing
- ABBV-4083, Albendazole
- Where
- 2 sites in Democratic Republic of the Congo
- Volunteers
- 153 people
- Sponsor
- AbbVie
Herpes Simplex Virus Infection
Study to Evaluate Safety, Tolerability, and Pharmacokinetics of UB-621 in Healthy Volunteers
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of a single subcutaneous dose of UB-621 in healthy volunteers.
- Trial name
- NCT02346760
- Testing
- UB-621
- Where
- Taiwan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- United BioPharma
Penile/Perineal /Perianal Intraepithelial Neoplasia, Anal Intraepithelial Neoplasia
A Phase III Trial to Evaluate the Efficacy, Immunogenicity and Safety of a Recombinant Human Papillomavirus 9-Valent (Types 6, 11, 16, 18, 31, 33, 45, 52, 58) Vaccine (E.Coli) in Chinese Males
This phase III clinical trial was designed to evaluate the efficacy, immunogenicity and safety of a Recombinant Human Papillomavirus 9-Valent (Types 6, 11, 16, 18, 31, 33, 45, 52, 58) Vaccine (E.Coli) manufactured by Xiamen…
- Conditions
- Penile/Perineal /Perianal Intraepithelial Neoplasia, Anal Intraepithelial Neoplasia, Penile/Perianal/Perineal Cancer, Anal Cancer
- Trial name
- NCT06866574
- Testing
- Recombinant Human Papillomavirus 9-Valent (Types 6, 11, 16, 18, 31, 33, 45, 52, 58) Vaccine (E.coli), Aluminum Adjuvant
- Where
- 4 sites in China
- Volunteers
- 9,300 people, healthy volunteers welcome
- Sponsor
- Xiamen University
Leishmaniasis, Cutaneous
Pharmacokinetics, Safety, and Efficacy Trial of WR 279,396 (Paromomycin + Gentamicin Topical Cream) and Paromomycin Topical Cream for the Treatment of Cutaneous Leishmaniasis in Panama
The objectives of the study are to evaluate the pharmacokinetics (PK), safety, and efficacy of WR 279,396 (Paromomycin + Gentamicin Topical Cream) and Paromomycin Topical Cream in subjects with cutaneous leishmaniasis (CL).
- Trial name
- NCT01083576
- Testing
- WR 279,396 (15% paromomycin + 0.5% gentamicin topical cream), Paromomycin Alone Cream (15% paromomycin topical cream)
- Where
- Panama
- Volunteers
- 30 people
- Sponsor
- U.S. Army Medical Research and Development Command
Streptococcal Infections
Comparative Trial of Oral Penicillin Versus Cefuroxim for Treatment of Perianal Streptococcal Dermatitis
The goal of the study is to investigate, which of two antibiotic treatments - oral penicillin for 10 days or oral cefuroxim for 7 days - is more successful for patients (1-16 years of age) with perianal dermatitis caused by group…
- Trial name
- NCT00261742
- Testing
- Penicillin versus cefuroxim per os
- Where
- Switzerland
- Volunteers
- 194 people
- Sponsor
- University Children's Hospital Basel
Covid19, Rheumatic Diseases
COVID-19 in a Single Large UK Rheumatology Centre and Impact on QOL
The COVID-19 pandemic represents a threat to rheumatology patients. National advice for patients to 'shield' is based on risk stratification of therapies and other risk factors.
- Trial name
- CRISP (NCT04542031)
- Testing
- Questionnaire
- Where
- United Kingdom
- Volunteers
- 1,010 people
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Covid19, Telogen Effluvium
COVID-19 Induced Telogen Effluvium
This study inquires about the development of Telogen effluvium following the SARS-CoV-2 infection
- Conditions
- Covid19, Telogen Effluvium, SARS-CoV Infection, Alopecia
- Trial name
- NCT04834102
- Testing
- Blood Tests
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Hidradenitis Suppurativa
Aviclear for Hidradenitis Suppurativa (HS)
The objective is to evaluate the safety and efficacy of the Cutera 1726 nm laser system (also referred to as AviClear) for the treatment of HS.
- Trial name
- NCT06801795
- Testing
- AviClear
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Miami
Onychomycosis
A Study to Evaluate the Efficacy and Safety of Oral VT-1161 in Patients With Onychomycosis of the Toenail
Several properties of VT-1161 suggest that it might be a safer and more effective treatment for onychomycosis of the toenail (also known as toenail fungus) than other oral antifungal medicines.
- Trial name
- NCT02267356
- Testing
- VT-1161
- Where
- 33 sites in United States
- Volunteers
- 259 people
- Sponsor
- Viamet
Hidradenitis Suppurativa
Biomarkers In Hidradenitis Suppurativa Participants Receiving Brodalumab
Phase 0 Study of Brodalumab in patients with moderate to severe Hidradenitis Suppurativa to identify biomarkers of disease activity and clinical response.
- Trial name
- NCT03960268
- Testing
- Brodalumab
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Rockefeller University
Genital Warts, HPV Infections
Human Papillomavirus (HPV) Genotypes in Genital Warts in Colombian Population
HPV infection has been recognized as the most prevalent sexual transmitted infection worldwide. Burden of many HPV related diseases is well known particularly regarding the different associated cancers (cervical, anal, vaginal…
- Trial name
- GWprofamilia (NCT00847340)
- Testing
- Biopsy Excisional
- Volunteers
- 342 people
- Sponsor
- La Fundacion para la Investigacion y el Desarrollo
Diabetic Foot Ulcer, Infection
Topical PluroGel N for the Treatment of Mildly Infected Diabetic Foot Ulcers
This will be a randomized, double-blind (evaluator-blind), vehicle-controlled study of 50 enrolled subjects. Adult subjects (greater than 18 years old) who present with a mildly infected diabetic foot ulcer (IDSA criteria) having…
- Trial name
- NCT02091596
- Testing
- PluroGel N, PluroGel
- Where
- 15 sites in United States
- Volunteers
- 42 people
- Sponsor
- PluroGen Therapeutics, Inc
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