Clinical trials: Skin Infection
Tinea Pedis
Therapeutic Equivalence and Safety of Two Econazole Nitrate Cream, 1% Products in Tinea Pedis
To evaluate the therapeutic equivalence of the Test formulation, econazole nitrate cream, 1% to the Reference product, econazole nitrate cream, 1% in the treatment of tinea pedis.
- Trial name
- NCT03129321
- Testing
- Econazole Nitrate Cream, 1%
- Volunteers
- 876 people
- Sponsor
- Mylan Inc.
Condyloma Acuminata, Genital Warts
Efficacy and Safety Profiles of SR-T100 Gel on External Genital Warts/Condyloma Acuminate(EGWs)
To evaluate the efficacy of SR-T100 gel by observing total clearance rate of treated baseline EGW(s) on the treated area.
- Conditions
- Condyloma Acuminata, Genital Warts, Condylomata Acuminata, Venereal Warts
- Trial name
- NCT01796821
- Testing
- Vehicle gel, SR-T100 gel with 1.0 % SM, SR-T100 gel with 2.3% SM
- Where
- 3 sites in Taiwan
- Volunteers
- 138 people
- Sponsor
- G&E Herbal Biotechnology Co., LTD
Surgical Site Infection
Time of Permanence of Dressing Following Breast Reconstruction
This randomized clinical trial was designed to assess the influence of time of dressing after breast reconstruction procedures on surgical site infections rates and skin colonization.
- Trial name
- NCT01148823
- Testing
- Incisions covered for 1 day, Incisions covered for 6 days
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Daniela Francescato Veiga
Skin Cancer, Infection Reactivation
Viral Reactivation and Skin Cancer
Several studies show that the incidence of skin cancer parallels the length and depth of immunosuppression. This study will analyze the correlation of viral reactivation and skin cancer in organ transplant recipients.
- Trial name
- NCT02395562
- Where
- Switzerland
- Volunteers
- 1,200 people
- Sponsor
- University of Zurich
Atopic Dermatitis, Hidradenitis Suppurativa
Linking Epidermal Barrier Function With Anti-Oxidant Defense Mechanisms in Skin Conditions
Investigators will sample the skin and blood of patients with chronic skin conditions (including but not limited to atopic dermatitis (AD), contact dermatitis, hidradenitis suppurativa (HS), and psoriasis) to study the expression…
- Conditions
- Atopic Dermatitis, Hidradenitis Suppurativa, Contact Dermatitis, Psoriasis
- Trial name
- NCT03198390
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Mucocutaneous Leishmaniasis
Dedicated QT Study in Bolivian Patients Taking Impavido® (Miltefosine) for Mucocutaneous Leishmaniasis
This study is a Phase 4, open-label, single group study in which at least 40 adult patients undergoing miltefosine treatment for mucocutaneous leishmaniasis (CL and ML) will be assessed by 12-lead ECG for prolongation of the…
- Trial name
- NCT02429518
- Testing
- Miltefosine
- Where
- Bolivia
- Volunteers
- 42 people
- Sponsor
- Knight Therapeutics (USA) Inc
Inflammatory Bowel Disease, Crohn Disease
Prevalence and Clinical Course of Chronic Hep B Infection in IBD and Rheumatologic Disease
This study aims to determine the prevalence of HBV infection in patients with IBD and rheumatologic disease, and to assess the impact of immunosuppressive therapy on viral load and clinical course of IBD patients.
- Conditions
- Inflammatory Bowel Disease, Crohn Disease, Ulcerative Colitis, Rheumatic Diseases
- Trial name
- NCT02128503
- Testing
- HBV DNA level monitoring
- Where
- Hong Kong
- Volunteers
- 430 people
- Sponsor
- Chinese University of Hong Kong
Coronavirus Infection
Prevalence and Incidence of COVID-19 Infection in Patients With Chronic Plaque Psoriasis on Immunosuppressant Therapy
This study will assess the prevalence and incidence of COVID-19 infection in patients with chronic plaque psoriasis on immunosuppressant therapy.
- Trial name
- NCT04324866
- Testing
- Nasopharyngeal swab
- Volunteers
- 300 people
- Sponsor
- Universita di Verona
Anogenital Warts, Condylomata Acuminata
Safety and Efficacy Study of Topical AP611074 Gel to Treat Genital Warts
The purpose of this study is to determine the safety, tolerability and efficacy of the topical application of AP611074 5% gel during 6 weeks on ano-genital warts caused by human papillomavirus (HPV).
- Conditions
- Anogenital Warts, Condylomata Acuminata, Human Papillomavirus Infection
- Trial name
- NCT01532102
- Testing
- AP611074
- Where
- 4 sites in Argentina, France
- Volunteers
- 24 people
- Sponsor
- Anaconda Pharma
Recurrent Acute Leukemia, Recurrent B Acute Lymphoblastic Leukemia
Flotetuzumab for the Treatment of Relapsed or Refractory Advanced CD123-Positive Hematological Malignancies
This phase I trial studies the best dose and side effects of flotetuzumab for the treatment of patients with blood cancers (hematological malignancies) that have spread to other places in the body (advanced) and have come back…
- Conditions
- Recurrent Acute Leukemia, Recurrent B Acute Lymphoblastic Leukemia, Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive
- Trial name
- NCT04681105
- Testing
- Acetaminophen, Dexamethasone, Diphenhydramine
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- City of Hope Medical Center
Mycobacterium Ulcerans Infection
WHO Drug Study for Buruli Ulcer - Comparison of SR8 and CR8
This is a WHO-sponsored trial. Combination therapy with streptomycin and rifampicin has been the standard antibiotic treatment for M. ulcerans infection since 2004.
- Trial name
- NCT01659437
- Testing
- Clarithromycin Extended Release, Streptomycin intramuscular injection
- Where
- 5 sites in Benin, Ghana
- Volunteers
- 310 people
- Sponsor
- University Medical Center Groningen
Recurrent Herpes Labialis
Place Controlled Study to Treat Recurrent Herpes Labialis.
About 80% of the worldwide population is positive on HSV antibodies. In the United States the lifetime prevalence of recurrent herpes labialis is estimated at 20% to 40%, with approximately 100 million episodes occurring in the…
- Trial name
- NCT00914745
- Testing
- Ointment
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Tinea Pedis
BE Study of Naftifine HCL
The current study was randomized, double blind, placebo-controlled, prospective, multicenter, comparative therapeutic equivalence study. The study duration for each patient was 6 weeks: Following were the visit details.
- Trial name
- NCT02633813
- Testing
- Naftifine hydrochloride 2%, Naftin® 2% (Naftifine hydrochloride 2%)
- Where
- 14 sites in United States, Dominican Republic
- Volunteers
- 693 people
- Sponsor
- Genzum Life Sciences
Skin Diseases, Infectious
Study Comparing Tigecycline and Vancomycin With Aztreonam in Complicated Skin and Skin Structure Infections
To compare the safety and the efficacy of tigecycline to vancomycin with aztreonam in treating hospitalized patients with complicated skin and/or skin structure infections.
- Trial name
- NCT00228410
- Testing
- Tigecycline, vancomycin with aztreonam
- Volunteers
- 503 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Onychomycosis
Alpha-bisabolol for Onychomycosis Treatment
Clinical, interventional, longitudinal study with random sampling. 60 patients will be divided into three groups, group A: control group, drug recommended by the Brazilian Society of Dermatology, group B: alpha bisabolol-based…
- Trial name
- NCT04940520
- Testing
- Drug recommended by the Brazilian Society of Dermatology, Alpha bisabolol product and laser, Alpha bisabolol product
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Universidade do Vale do Sapucai
Intravenous Drug Abuse, HIV Infections
Reducing Health Problems Associated With Injection Drug Use
The purpose of this study is to develop and test an intervention to reduce bacterial and viral infections among injection drug users.
- Trial name
- NCT01128920
- Testing
- Skin and Needle Hygiene Intervention, No intervention - assessment-only condition
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Northern Colorado
Acne Vulgaris II or III Degree, Boils
Open and Comparative Study to Measure Tolerability and Efficacy of Taro Elixir
To measure the efficacy of Taro Elixir compare with Oxytetracycline in the treatment of boils or acne.
- Trial name
- E01GOU-INH0109 (NCT01032499)
- Testing
- oxytetracycline, taro elixir, Taro Elixir
- Where
- 4 sites in Brazil
- Volunteers
- 120 people
- Sponsor
- Laboratorios Goulart S.A.
Hookworm Infection
Prevalence of Hookworm Infection and Community Preparedness for Hookworm Vaccine Trials in Endemic Areas of Brazil
Na-ASP-2 is a protein expressed during the larval stage of the N. americanus hookworm life cycle. In a clinical study in previously hookworm-infected adults in Brazil, this protein induced urticarial reactions (rash) in a subset…
- Trial name
- NCT00939198
- Testing
- Na-ASP-2 Skin Test Reagent
- Where
- Brazil
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Albert B. Sabin Vaccine Institute
Breast Cancer, COVID-19
Timing of Surgery and the Evolution of Postoperative Outcomes in Breast Cancer Patients Undergoing Surgical Intervention Following Recovery From SARS-CoV-2 Infection
Perioperative SARS-CoV-2 infection significantly increases the risk of postoperative complications and mortality, while also exerting long-lasting impacts on multiple organs and systems.
- Conditions
- Breast Cancer, COVID-19, Postoperative Complications
- Trial name
- NCT06319209
- Testing
- Preoperative resolved COVID-19
- Where
- China
- Volunteers
- 392 people
- Sponsor
- Fujian Medical University Union Hospital
Hepatitis C, Lichen Planus
Off-Label Use of Ribavirin in Management of Mucocutaneous Extrahepatic Manifestations of HCV Infection
This study will be conducted on 30 patients with mucocutaneous complaints and documented HCV infection. The study will be done at Tropical medicine department , Tanta university.
- Conditions
- Hepatitis C, Lichen Planus, Vasculitis, Autoimmune Diseases
- Trial name
- NCT02261662
- Testing
- Ribavirin, Betamethasone
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
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