Clinical trials: Skin Microbiota
Breast Cancer, Cancer Cachexia
Cachexia and Gut Microbiota in Patients With Breast Cancer Receiving Home Care
This study aims to evaluate the possible association between cancer cachexia and Gut Microbiota (GM) in patients with Breast Cancer (BC) cared at home.
- Trial name
- GM_ANT (NCT07653698)
- Testing
- Probiotic Mixture
- Volunteers
- 140 people
- Sponsor
- Fondazione ANT Franco Pannuti ETS
Scleroderma, Systemic
Gut Microbiota Transplantation in Systemic Sclerosis
Systemic Sclerosis (SSc) is a progressive multi-organ disorder with high disease burden. Life expectancy in SSc is reduced by 25-40 years, mainly due to cardiopulmonary and gastro-intestinal (GI) disease involvement; and a very…
- Trial name
- ReSScue (NCT03444220)
- Testing
- Anaerobically Cultivated Human Intestinal Microbiota, Anaerobically Cultivated medium
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Oslo University Hospital
Melanoma (Skin) Stage IV, Melanoma (Skin Cancer)
Dietary Fiber to Induce Gut Microbiota-mediated Response to Immunotherapy in Melanoma.
Previous research has shown that a higher fiber intake may have a beneficial effect on the intestinal health and improve the effectiveness of immunotherapy, but this is not certain.
- Conditions
- Melanoma (Skin) Stage IV, Melanoma (Skin Cancer), Melanoma Metastatic, Melanoma Advanced
- Trial name
- FIGURE-IM (NCT07686835)
- Testing
- Dried chicory roots
- Where
- 2 sites in Netherlands
- Volunteers
- 70 people
- Sponsor
- Radboud University Medical Center
Sjogren's Syndrome
Descriptive Study of Variations in Serum Translocation Markers of the Intestinal Microbiota in Patients With Gougerot-Sjögren Syndrome According to Disease Activity
Gougerot-Sjögren syndrome or Sjögren syndrome is a chronic autoimmune disease belonging to connectivitis, the classic triad of symptoms being the association of a sicca syndrome (generally predominant in the mouth and / or…
- Trial name
- IMISS (NCT04462601)
- Testing
- Biomarker detection
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Psoriasis Vulgaris, Seborrheic Dermatitis
Comparison of Scalp Microbiota of the Psoriasis and Seborrheic Dermatitis Patients
A sterile swap specimen taken from the scalp of the patients with psoriasis vulgaris or seborrheic dermatitis and the volunteer control group will be examined in our study.
- Conditions
- Psoriasis Vulgaris, Seborrheic Dermatitis, Microbial Colonization
- Trial name
- NCT03807453
- Testing
- Microbiota
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Medeniyet University
Juvenile Idiopathic Arthritis
(1,3)-Béta-D-Glucan Levels at Diagnosis of Juvenile Idiopathic Arthritis and Its Correlation With Activity's Disease : a Cohort Sudy
Juvenile idiopathic arthritis (JIA) is the most common pediatric rheumatic disease of childhood. Most children still experience prolonged periods of active disease, however, there is still lack of effective and specific markers…
- Trial name
- BDG -JIA (NCT03984669)
- Testing
- The Juvenile Disease Activity Score (JADAS), (1-3)-ß-D-Glucan (BDG) assay (Fungitell)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Scalp Dermatitis, Dermatitis
Effects on the Scalp Microbiota of a 1% Selenium Disulfide and 1% Salicylic Acid Shampoo After 2% Ketaconazole Foaming Gel Treatment for Scalp Seborrheic Dermatitis
The aim of this study was to investigate the changes in the scalp bacterial and fungal microbiota in subjects afflicted with a scalp seborrheic dermatitis (SSD) during a 2% ketoconazole-based treatment followed by a maintenance…
- Trial name
- NCT04057950
- Testing
- cosmetic product
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Systemic Sclerosis
Study of the Intestinal Microbiota of Patients With Systemic Sclerosis
The term gut microbiota describes the entire intestinal microbial communities. Studies have established the important role played by the gut microbiome in modulating vital functions of the healthy host.
- Trial name
- SCLEROMICROBIO (NCT04791280)
- Testing
- Faeces collection
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Triple Negative Breast Cancer
Gut and Intratumoral Microbiome Effect on the Neoadjuvant Chemotherapy-induced Immunosurveillance in Triple Negative Breast Cancer
The probability of pCR in TNBC patients receiving standard of care neoadjuvant chemotherapy treatment is associated with the dominance of specific intestinal and intratumoral microbiota that promote anti-tumor immunosurveillance.
- Trial name
- NCT03586297
- Where
- 3 sites in United States
- Volunteers
- 49 people
- Sponsor
- Hackensack Meridian Health
Melanoma, Stage II
Explorative Study on Addition of High-fiber Dried Chicory Root in Patients With an Intermediate to High-risk Cutaneous Melanoma.
Exploring the effect of supplementation with daily addition of prebiotic dried chicory root (WholeFiberTM) for 6 weeks on fecal SCFA levels, gut microbial composition and immune cell composition in minimal stage II A melanoma…
- Trial name
- MELFIB (NCT07206017)
- Testing
- prebiotic dried chicory root (WholeFiber)
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- University Medical Center Groningen
Lupus Erythematosus, Systemic, Gastrointestinal Microbiome
Assessment of Cognitive Function and Gut Microbiota Analysis in Real World Patients With Lupus Cerebrovascular Disease
Based on clinical manifestations, laboratory data and intestinal microflora detection, the cognitive function characteristics of patients with systemic lupus erythematosus and cerebrovascular disease and its relationship with…
- Trial name
- NCT05636670
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Atopic Dermatitis
Effects of a Mixed Chinese Herbal Formula on Atopic Dermatitis
The aim of this study is to investigate the clinical therapeutic effects of a mixed Chinese herbal formula (CHF) in treating atopic dermatitis (AD) based on its effects on cytokine levels and immune cell counts.
- Trial name
- NCT05455060
- Testing
- Chinese herbal formula (CHF)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Gut Microbiota, Gastrointestinal Symptoms
Mother-Infant Cohort Study in Malaysia and China
This mother-infant cohort study aims to determine the geographic differences in the microbial profiles in breast milk from mothers living in Malaysia and China that are potentially important determinants of infant development.
- Conditions
- Gut Microbiota, Gastrointestinal Symptoms, Temperament, Eczema
- Trial name
- NCT04919265
- Testing
- No intervention - mother-infant cohort study
- Where
- Malaysia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Rheumatoid Arthritis
Methotrexate in Patients with Early Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic inflammatory disease primarily affecting the small joints of hands and feet, but may also present with systemic, extraarticular features.
- Trial name
- MTXRA (NCT05353829)
- Testing
- Methotrexate
- Where
- 13 sites in Sweden
- Volunteers
- 212 people
- Sponsor
- Region Västerbotten
Rheumatoid Arthritis, Ankylosing Spondylitis
Safety and Efficacy of Capsule FMT in Treatment-naïve Patients With Newly Diagnosed Chronic Inflammatory Diseases
PURPOSE: The main purpose is to explore clinical efficacy and safety associated with capsule FMT (cFMT) performed in newly diagnosed, untreated patients with rheumatic and gastrointestinal chronic inflammatory diseases (CIDs).
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis, Crohn Disease
- Trial name
- FRONT (NCT04924270)
- Testing
- Faecal microbiota transplantation
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Odense University Hospital
Eczema
Impact of a Daily Application of an Omega-3 Monoglycerides Based Serum and Cream on the Skin Microbiota
This exploratory study aims to investigate the prebiotic potential of daily application of an omega-3 serum and cream to skin affected by eczema. The study will also collect data on any potential adverse effects of the products.
- Trial name
- COS-PBP-03 (NCT07583121)
- Testing
- Omega-3 monoglyceride based topical treatment
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- SCF Pharma