Clinical trials: Skin Physiology
Atopic Dermatitis Eczema
Effect of Ectoin Dermatitis Cream 7% on Skin Hydration and Skin Barrier Function
The aim of this prospective, uncontrolled clinical study is to evaluate the clinical effect of Ectoin® Dermatitis Cream-EHK02 on skin hydration and transepidermal water loss (TEWL) in subjects with atopic dermatitis after single…
- Trial name
- NCT04097327
- Testing
- Ectoin Dermatitis Cream 7% (EHK02)
- Where
- Germany
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Bitop AG
Atopic Dermatitis
Effects of Tralokinumab Treatment of Atopic Dermatitis on Skin Barrier Function
Effects of tralokinumab treatment of atopic dermatitis on skin barrier function.
- Trial name
- TraSki (NCT04556461)
- Testing
- Tralokinumab
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Prof. Dr. Stephan Weidinger
Breast Cancer
Goserelin Acetate Study for Ovarian Function in Patients With Primary Breast Cancer
Primary Objective: To determine the effectiveness of goserelin acetate (Zoladex) in preserving ovarian function in premenopausal women undergoing neoadjuvant and/or adjuvant chemotherapy for primary invasive breast cancer by…
- Trial name
- NCT00429403
- Testing
- Goserelin
- Where
- 2 sites in United States, Japan
- Volunteers
- 1 people
- Sponsor
- M.D. Anderson Cancer Center
Systemic Lupus Erythematosus
Respiratory Function, Physical Activity and Fatigue in SLE
Increasing awareness of possible pulmonary involvement in patients with systemic lupus erythematosus (SLE) will enable earlier diagnosis of the disease and minimize damage accumulation.
- Trial name
- NCT07193745
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Melis Usul
Skin Care
A Proof of Concept Clinical Study to Investigate the Effects of an Experimental Cosmetic Moisturiser on the Barrier Function of Human Skin on the Face and Forearm
The objective of this POC clinical study is to investigate the impact of the test product (Developmental Cosmetic Moisturising Cream) on skin barrier function and skin moisturisation on the forearm and face after 4 weeks of twice…
- Trial name
- NCT03216265
- Testing
- Test product (Moisturising cream), Positive control (Commercial market place moisturising cream), No treatment
- Where
- Germany
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Breast Cancer
A Prospective Study to Evaluate the Effect of Systemic Adjuvant Therapy on the Cognitive Function of Breast Cancer Patients
The primary objective of this prospective pilot study is to examine the variation of cognitive function at various time-points in stage I-III breast cancer patients who have undergone or are undergoing adjuvant systemic therapy…
- Trial name
- NCT01596439
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Patellofemoral Pain Syndrome
Quadriceps Strengthening At Different Angles in Patellofemoral Pain
Introduction: Patellofemoral pain (PFP) is characterized by anterior, retropatellar and/or peripatellar pain during activities such as running, squatting, kneeling, or prolonged sitting.
- Trial name
- NCT06502795
- Testing
- Protected Range Quadriceps Strengthening group, Patient-Guided Range Quadriceps Strengthening group
- Where
- Brazil
- Volunteers
- 110 people
- Sponsor
- Universidade Federal do Ceara
Candidiasis, Chronic Mucocutaneous
CAMB/MAT2203 in Patients With Mucocutaneous Candidiasis
This is an open-label, dose-titration trial to study the efficacy, safety, and pharmacokinetics of oral cochleate amphotericin B (CAMB) in the treatment of mucocutaneous candidiasis infections in patients who are refractory or…
- Trial name
- CAMB (NCT02629419)
- Testing
- Amphotericin B
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Matinas BioPharma Nanotechnologies, Inc.
System Lupus Erythematosus(SLE)
The Effect of Exercise on Cognitive Functions in Individuals With Systemic Lupus Erythematosus
Study Objective: To examine the effect of aerobic exercise on disease activity and cognitive functions in patients diagnosed with SLE. Study Goals: 1.
- Trial name
- NCT07622251
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Istanbul Galata University
Atopic Dermatitis, Dermatitis Atopic
Dupilumab Skin BArrier Function and LIpidomics STudy in Atopic Dermatitis in China
This is a 16-week, open label, exploratory study designed to investigate dupilumab's effect on skin barrier function as measured by transepidermal water loss (TEWL) before and after skin tape stripping.
- Trial name
- BALISTAD-CN (NCT05624112)
- Testing
- Dupilumab
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Sanofi
Breast Cancer
Italian Validation of a Tool for Assessing Sexual Function After Breast Cancer, FSFI-BC
This is a validation study of the italian language for the Female Sexual Function Index-Breast Cancer questionnaire. The validation of the instrument in Italian will allow the identification of possible issues related to sexual…
- Trial name
- NCT06340386
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- European Institute of Oncology
Healthy, Systemic Sclerosis
Systemic Sclerosis Clinical and Biomarker Study
The primary objective of the study is to assess the change in systemic sclerosis (SSc)-associated gastrointestinal (GI) tract symptoms over a 1-year period in participants with SSc.
- Trial name
- NCT02531009
- Volunteers
- healthy volunteers welcome
- Sponsor
- Biogen
Rheumatoid Arthritis
Promoting Engagement in Physical Activity in Early Rheumatoid Arthritis: Proof of Concept Study
People with rheumatoid arthritis have indicated that they would like better support to remain physically active following diagnosis and would welcome a physical activity programmes delivered outside of a secondary care setting by…
- Trial name
- PEPA-RA (NCT04321798)
- Testing
- Physical Activity
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of the West of England
Hypothalamus-Pituitary-Adrenal Axis Assessement, Topical Steroid Therapy in Chronic Skin Diseases
Does Topical Steroid Treatment Impair the Adrenal Function?
The purpose of this study is to determine if topical steroids treatment for different skin diseases suppress the adrenal cortisol production.
- Trial name
- NCT00476489
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- HaEmek Medical Center, Israel
Spinal Cord Injuries, Spina Bifida
Downstream Effects of Personalized 'Top-down' Participation-based Interventions Among Youth With Physical Disabilities
Participation in community-based activities is essential to the health and well-being of youth with physical disabilities; yet, it is extremely restricted.
- Conditions
- Spinal Cord Injuries, Spina Bifida, Musculoskeletal Disorder, Juvenile Arthritis
- Trial name
- NCT05784285
- Testing
- Engagement in a 8-week community-based activity program
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- McGill University
Breast Cancer
Radiation Therapy and Thymus Function in Young Women With Breast Cancer
Breast cancer treatment sometimes includes radiation to the breast or chest wall. There is a small gland, called the thymus, located in the upper chest that may receive a small amount of the radiation aimed at the breast.
- Trial name
- NCT07725172
- Testing
- Blood draw for the laboratory assessment
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Duke University
Breast Cancer
Effect of Telemonitoring on Functionality, Quality of Life and Risk of Lymphedema in Breast Cancer Survivors
The objective of the study is to evaluate the effectiveness of telemonitoring in the dysfunctions of the upper limbs in activities of daily living, quality of life and prevention of lymphedema in women undergoing treatment for…
- Trial name
- NCT04779450
- Testing
- Kinesiotherapy protocol, Usual orientations
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of the State of Santa Catarina
Lipedema
Mind-Body Chair Yoga for Functional Mobility in Individuals With Lipedema
Lipedema is a chronic condition characterized by abnormal accumulation and distribution of adipose tissue, most commonly affecting the lower extremities, and may be associated with swelling, discomfort, reduced mobility, and…
- Trial name
- LIP-MOVE (NCT07917195)
- Testing
- Mind-Body Chair Yoga + Support Group, Support Group
- Volunteers
- 73 people
- Sponsor
- Cynthia Beers
Immune Thrombocytopenia
The Association Between Platelet Reactivity and Bleeding Risk in Adult ITP
It seems reasonable to assume that patients who present significant bleeding symptoms may have different quality of platelets than those without bleeding.
- Trial name
- NCT03377439
- Testing
- Platelet function tests
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Shandong University
Hidradenitis Suppurativa, Wide Excision
Quality of Life After Wide Surgical Excision in Patients With Hidradenitis Suppurativa
Patients undergoing wide surgical excision of their hidradenitis suppurativa areas are asked by telephone about their quality of life by standard questionnaires (WHOQOL-BREF, DLQI, Skindex, MHF, FLQA-d) and their sexual function…
- Trial name
- NCT02593604
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University Hospital Schleswig-Holstein