Clinical trials: Skin Recovery, open to volunteers
Skin Barrier Disruption and Recovery
Evaluation of a Peptide Cream on the Forearm Skin Recovery of Healthy Volunteers
The goal of this clinical trial is to evaluate the efficacy of a topical peptide-based formulation containing Acetyl Hexapeptide-37 in promoting skin barrier recovery after controlled disruption in healthy adult participants.
- Trial name
- NCT07614698
- Testing
- Acetyl Hexapeptide-37
- Where
- Croatia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Abdominal Wound Dehiscence, Necrotizing Soft Tissue Infection
Myriad™ Augmented Soft Tissue Reconstruction Registry
This is an observational study designed to evaluate the safety and clinical outcomes of Myriad™ in soft tissue reconstruction procedures.
- Conditions
- Abdominal Wound Dehiscence, Necrotizing Soft Tissue Infection, Lower Extremity Wound, Pilonidal Sinus
- Trial name
- MASTRR (NCT05243966)
- Testing
- Myriad Matrix™ and Myriad Morcells™
- Where
- 15 sites in United States
- Volunteers
- 800 people
- Sponsor
- Aroa Biosurgery Limited
Thoracic Surgical Procedures, Postoperative Recovery
Impact of Topical Aromatherapy on Postoperative Quality of Recovery After Lung Resection
The key to early surgery recovery lies in optimal and immediate control of postoperative pain. Despite standard pain management protocols, lung resection is often associated with acute, neuropathic, or chronic pain, compounded by…
- Conditions
- Thoracic Surgical Procedures, Postoperative Recovery, Pain, Complementary Therapies
- Trial name
- AromaQoR (NCT07622602)
- Testing
- topical application of the "AromaQoR" formulation, topical application of sweet almond vegetable oil
- Volunteers
- 124 people
- Sponsor
- University Hospital, Toulouse
Breast Reconstruction, Breast Cancer
Optimizing Postoperative Recovery After Breast Reconstruction With Autologous Tissue (BestDIEP)
Women who have their breast reconstructed with autologous tissue seem to be more satisfied with their breast. However, autologous breast reconstruction entails a bigger operation, and the usage of more health care resources, than…
- Trial name
- BestDIEP (NCT05363189)
- Testing
- Venous augmentation, Traditional ERAS (enhanced recovery after surgery) protocol, Sahlgrenska recovery protocol
- Where
- Sweden
- Volunteers
- 380 people
- Sponsor
- Vastra Gotaland Region
Breast Cancer
Oncologic Outcomes and Toxicities of Salvage Treatment in Patients With Locoregionally Recurrent Breast Cancer
The purpose of this study is to evaluate clinical outcomes and adverse events of salvage treatment for locoregional recurrence of breast cancer.
- Trial name
- SALT-LRR (NCT05933733)
- Testing
- Salvage treatment (surgery and/or radiation therapy)
- Where
- South Korea
- Volunteers
- 190 people
- Sponsor
- Samsung Medical Center
Mental Fatigue, Cognitive Performance
Predicting Declines in Attention and Memory During a Prolonged Mental Task
This study will investigate whether heart activity and changes in the skin's ability to conduct electricity can help predict performance during a demanding computer task.
- Trial name
- COG-PRED (NCT07877389)
- Testing
- Individually Calibrated Time Load Dual-back Task With Seated Rest
- Where
- Poland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- DSW Ideis University
Wound Healing Disturbance of
HIP-STITCH (Wound Recovery After THA)
This prospective randomised trial will investigate the effect of four different suturing techniques (Monocryl, Vicryl Rapide with Indermil skin glue, Dermabond Prineo, and Stryker Zip) on the amount of aberrant wound recovery…
- Trial name
- NCT06275776
- Testing
- Ethicon Monocryl Smooth Suture, Ethicon Vicryl Rapide Braided Suture, Flexifuze Indermil Topical Skin Adhesive
- Where
- Netherlands
- Volunteers
- 236 people
- Sponsor
- Reinier Haga Orthopedisch Centrum
Rheumatic Diseases, Rheumatoid Arthritis (RA)
Pain Neuroscience Education and Vagus Nerve Stimulation on Recovery in Individuals With Rheumatoid Arthritis
In the context of this randomized controlled study, patients who are diagnosed with Rheumatoid arthritis in Cerrahpaşa Faculty of Medicine Hospital, will be taken into a rehabilitation program by a qualified physiotherapist to…
- Trial name
- NCT07274124
- Testing
- Pain Neuroscience Education, Vagal Nerve Stimulation, Structured Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Medipol University
Breast Cancer Surgery, Quality of Life
Quality of Life After Breast Cancer Surgery
The goal of this observational study is to prospectively collect data on quality of life after oncoplastic breast surgery. Participants will be followed-up and answer quality of life questionnaire for a duration of 5 years after…
- Trial name
- SOCOM-QoL (NCT06761196)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- Centre Hospitalier de Colmar
Diabetic Foot Ulcer
Effectiveness of Diabetic Recovery Shoes and Artificial Intelligence Supported Structured Exercise Program
This study aims to evaluate the effectiveness of the diabetic recovery sandal and artificial intelligence supported structured exercise program in individuals diagnosed with diabetic foot receiving hyperbaric oxygen therapy.
- Trial name
- NCT06515665
- Testing
- therapeutic foot orthosis
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Hacettepe University
Dupuytren Contracture
Evaluating Ultrasound-Guided Needle Knife for Dupuytren's Contracture
This study aims to evaluate the efficacy and safety of ultrasound-guided needle knife dissection in treating Dupuytren's contracture.
- Trial name
- DC-US (NCT06788847)
- Testing
- Ultrasound guided needle knife dissection
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mohamed Maher Ismail Ahmed Elashmawy
Coccidioidomycosis, Blastomycosis
Platform Trial for Salvage Consolidation Therapy in Dimorphic Fungi
This Phase II platform trial will evaluate the safety, tolerability, and effectiveness of investigational antifungal agents as salvage or consolidation therapy in adults with dimorphic fungal infections, including…
- Conditions
- Coccidioidomycosis, Blastomycosis, Histoplasmosis, Dimorphic Fungal Infection
- Trial name
- NCT07804368
- Testing
- Oteseconazole
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Minnesota
Breast Neoplasms
Optimizing Functional Recovery After Breast Cancer Treatment
The goal of this clinical trial is to determine the best way to promote participation in vocational, social, physical, and instrumental activities of daily living in people who have completed treatment for early stage breast…
- Trial name
- NCT07489053
- Testing
- Individually tailored education and guided application to promote activity participation, Individually tailored guided application, Individually tailored education
- Where
- United States
- Volunteers
- 352 people
- Sponsor
- MGH Institute of Health Professions
Immune Thrombocytopenia
TPO-RA Treatment on Immune Tolerance Induction of ITP Patients With Sustained Platelet Recovery After Treatment Termination
The aim of this study was to observe whether maintaining a high level of platelet count after TPO-RA in patients with primary immune thrombocytopenia (ITP) can induce immune tolerance, develop immune balance in ITP patients, and…
- Trial name
- NCT06478537
- Testing
- Hetrombopag Olamine, Aspirin
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Peking Union Medical College Hospital
Granulomatosis With Polyangiitis, Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis
Study of Salvage Therapy to Treat Patients With Granulomatosis With Polyangiitis
The purpose of this study is to identify the most promising therapeutic strategy for patients with granulomatosis with polyangiitis and inadequate response to standard of care therapy.
- Trial name
- SATELITE (NCT04871191)
- Testing
- Rituximab, Tocilizumab, Tofacitinib
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obstructive Jaundice, Pancreatic Head Cancer
Impact of Intraoperative PTCD Catheter Retention Versus Removal on Postoperative Short-term Outcomes After Pancreaticoduodenectomy in Obstructive Jaundice
Pancreaticoduodenectomy (PD) is a complex surgical procedure commonly performed for tumors of the pancreatic head and periampullary region.
- Conditions
- Obstructive Jaundice, Pancreatic Head Cancer, Periampullary Neoplasms, Biliary Tract Neoplasms
- Trial name
- NCT07532759
- Testing
- PTCD Catheter Removal, PTCD Catheter Retention
- Volunteers
- 100 people
- Sponsor
- Xu'an Wang
Breast Cancer
Reiki Breast Surgery QOL Project for Women Undergoing Breast Surgery
This pilot study will examine the impact of pre-operative Medical Reiki© on the psychosocial well-being and recovery of underserved women undergoing breast cancer surgery.
- Trial name
- NCT06524895
- Testing
- Medical Reiki
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Albert Einstein College of Medicine
Diabetic Foot Ulcer
On the Move: Center and Home-Based Exercise to Enhance Mobility in Diabetic Foot Ulcer Recovery
Foot ulcers and amputations are a common and feared complication for people with diabetes. People with a diabetic foot ulcer have a higher risk of dying within five years than people with diabetes without an ulcer.
- Trial name
- NCT06894563
- Testing
- 12-week exercise regimen, 12-week standard of care
- Volunteers
- 60 people
- Sponsor
- University of Maryland, Baltimore
Breast Cancer, Postoperative Recovery
ERAS Protocols in Breast Conserving Surgery
Enhanced Recovery After Surgery (ERAS) protocols have been of increasing interest in the surgical community for decades. The emphasis has been development of protocols to maximize pain control post-operatively without the use of…
- Trial name
- ERAS (NCT06938581)
- Testing
- ERAS Protocol, Standard Perioperative Care
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- University of Nebraska
Skin Barrier Disruption and Recovery
Helichrysum Italicum Extract in Irritant Contact Dermatitis
The goal of this clinical trial is to evaluate the efficacy and safety of a topical cream containing Immortelle (Helichrysum italicum) extract in promoting skin barrier recovery and reducing signs of irritant contact dermatitis…
- Trial name
- NCT07676253
- Testing
- Helichrysum italicum Extract Cream
- Where
- Croatia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine