Clinical trials: Skin Recovery
Pruritus
A Study to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-SK-1405
The primary objectives of the study are: To assess the mass balance recovery after a single PO dose of [14C]-SK-1405 To provide plasma, urine and faecal samples for metabolite profiling and structural identification
- Trial name
- NCT02846181
- Testing
- [14C]-SK-1405
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Sanwa Kagaku Kenkyusho Co., Ltd.
Gallstones
Safety Study of Keyhole Gallbladder Surgery With Removal of Gallbladder Via the Stomach Rather Than Through the Skin
The benefits of laparoscopic ("minimally invasive" or "keyhole") surgery for gallbladder removal (cholecystectomy) over open surgical procedures in terms of significant reductions in pain, scarring and recovery time are well…
- Trial name
- NCT01010685
- Testing
- Recovery of gallbladder via gastrotomy instead of via the skin
- Where
- United Kingdom
- Sponsor
- Colchester Hospital University NHS Foundation Trust
Breast Cancer
Effect of Perioperative Intravenous Lidocaine Infusion and Magnesium Infusion on the Functional Recovery After General Anesthesia in the Patients Undergoing Breast Mastectomy
Postsurgical pain is a relevant side effect following surgery which increases the risk of various complications and delays postoperative patient recovery.
- Trial name
- NCT02185859
- Testing
- Lidocaine, Magnesium Sulfate, Saline
- Where
- South Korea
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Irritant Contact Dermatitis
Regional Differences of Cutaneous Irritation and Its Effect on Skin Barrier Recovery
Irritant contact dermatitis induced by sodium lauryl sulphate (SLS) is often used as a model for testing efficacy of various topical preparations.
- Trial name
- NCT03231813
- Testing
- Sodium lauryl sulphate induced irritation, Emollient, moisturizing cream
- Where
- Croatia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Skin Barrier Disruption and Recovery
Evaluation of a Peptide Cream on the Forearm Skin Recovery of Healthy Volunteers
The goal of this clinical trial is to evaluate the efficacy of a topical peptide-based formulation containing Acetyl Hexapeptide-37 in promoting skin barrier recovery after controlled disruption in healthy adult participants.
- Trial name
- NCT07614698
- Testing
- Acetyl Hexapeptide-37
- Where
- Croatia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Breast Cancer, Cancer-related Fatigue
Behavioral Activation for Cancer-Related Fatigue After Breast Cancer Surgery
Cancer-related fatigue is common after breast cancer surgery and may persist during adjuvant treatment and early survivorship. This randomized controlled trial evaluated whether an 8-week graded behavioral activation intervention…
- Trial name
- NCT07799909
- Testing
- Behavioral Activation, Care as Usual
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Huaidong Cheng
Breast Cancer
Oncologic Outcomes and Toxicities of Salvage Treatment in Patients With Locoregionally Recurrent Breast Cancer
The purpose of this study is to evaluate clinical outcomes and adverse events of salvage treatment for locoregional recurrence of breast cancer.
- Trial name
- SALT-LRR (NCT05933733)
- Testing
- Salvage treatment (surgery and/or radiation therapy)
- Where
- South Korea
- Volunteers
- 190 people
- Sponsor
- Samsung Medical Center
Skin Recovery
A Study to Gain Information How Well Dexpanthenol Dermal Spray Helps the Skin to Recover After Laser Hair Removal in the Groin and Intimate Area
In this study, researchers want to learn more about the effect of dexpanthenol dermal spray on skin recovery after a dermatological procedure for hair removal (laser depilation) in the groin and intimate area in adult women.
- Trial name
- NCT03853525
- Testing
- BAY207543 (Bepanthol, Bepantol® Derma Spray), Semisolid vaseline
- Where
- Brazil
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Bayer
Knee Replacement Arthroplasty, Fibrosis
Knee Stiffness in Fibrosis Diathesis
At the standard follow-up moment one year after primary TKA for gonarthrosis, all patients will be checked for signs of fibrosis diathesis.
- Conditions
- Knee Replacement Arthroplasty, Fibrosis, Dupuytren's Disease
- Trial name
- NCT02294890
- Testing
- Total knee arthroplasty
- Volunteers
- 60 people
- Sponsor
- University Hospital Pellenberg
Breast Cancer
IRB-HSR# 13957: IV Lidocaine for Patients Undergoing Primary Breast Cancer Surgery:
The purpose of this study is to determine whether a local anesthetic drug (lidocaine) given during anesthesia intravenously (IV) through a needle in your vein,), can: 1. Help decrease pain after surgery. 2.
- Trial name
- NCT01204242
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of Virginia
Diabetic Foot Ulcer
Effectiveness of Diabetic Recovery Shoes and Artificial Intelligence Supported Structured Exercise Program
This study aims to evaluate the effectiveness of the diabetic recovery sandal and artificial intelligence supported structured exercise program in individuals diagnosed with diabetic foot receiving hyperbaric oxygen therapy.
- Trial name
- NCT06515665
- Testing
- therapeutic foot orthosis
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Hacettepe University
Breast Cancer, Colorectal Cancer
The ONE-MIND Study: Evaluating the Efficacy of Online Mindfulness-Based Cancer Recovery During Chemotherapy Treatment
Background: Chemotherapy treatment (CT) can have burdensome side effects such as fatigue, nausea-vomiting, and sleep problems that can significantly affect patients' quality of life.
- Conditions
- Breast Cancer, Colorectal Cancer, Chemotherapy Effect
- Trial name
- NCT03484000
- Testing
- Online Mindfulness Based Cancer Recovery (MBCR)
- Where
- Canada
- Volunteers
- 178 people
- Sponsor
- University of Calgary
Breast Cancer
Impact of Intraoperative Neurotization on Sensory Recovery of the Nipple and Breast Skin in Patients Undergoing Nipple Sparing Mastectomy With Immediate Implant-Based Reconstruction: NERSENSE, Prospective Randomized Control Study
The purpose of this clinical trial is to demonstrate the superiority of sensory recovery following sensory nerve coaptation compared with no sensory nerve coaptation in patients undergoing nipple-sparing mastectomy with immediate…
- Trial name
- NEARSENSE (NCT07902661)
- Testing
- Nerve anastomosis
- Volunteers
- 110 people
- Sponsor
- Gangnam Severance Hospital
Metastatic Breast Cancer
A Phase II, Single-Arm Trial of Poziotinib as Salvage Treatment in Patients With Metastatic Breast Cancer Who Has HER2 or EGFR Mutation or Activated AR or EGFR Pathway
Metastatic breast cancer (MBC) is an incurable disease and is needed to improve effective therapeutic strategies including targeted agents.
- Trial name
- NCT02544997
- Testing
- Poziotinib
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- Samsung Medical Center
Breast Cancer
Sorafenib and Vinorelbine in Treating Women With Stage IV Breast Cancer
RATIONALE: Sorafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as vinorelbine, work in different ways to stop the growth of tumor cells, either by…
- Trial name
- NCT00828074
- Testing
- sorafenib tosylate, vinorelbine ditartrate
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- City of Hope Medical Center
Wound Complication, Wound Heal
Immunonutrition and Carbohydrate Loading Strategies in Breast Reconstruction
This study is designed to test the following hypothesis: patients undergoing immediate alloplastic and autologous breast reconstruction following mastectomy that receive preoperative immunonutrition will experience a reduction in…
- Conditions
- Wound Complication, Wound Heal, Complications Wound, Surgical Wound Infection
- Trial name
- NCT03764943
- Testing
- Impact Advanced Recovery
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Wisconsin, Madison
Breast Neoplasms
Comparing Quality of Recovery Between ESPB and IV Lidocaine After Major Breast Cancer Surgery
The erector spinae plane block (ESPB) is gaining popularity as a regional anesthetic technique for major breast cancer surgery. Although there is controversy about its mechanism of action, emerging evidence suggests that clinical…
- Trial name
- NCT06490718
- Testing
- USG ESPB, Intravenous Infusion
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
Dupuytren's Contracture
Treatment Of Dupuytren's Contracture With Collagenase Clostridium Histolyticum Injection (Xiapex)
This study will evaluate the impact of Xiapex treatment on the range of motion (ROM) of the affected fingers and the patient and physician reported treatment satisfaction and disease severity and their relation to ROM.
- Trial name
- POINT X (NCT01229436)
- Testing
- Xiapex
- Where
- 28 sites in Denmark, France and 6 more
- Volunteers
- 254 people
- Sponsor
- Pfizer
Diabetic Foot
Trial of Vacuum Assisted Closure® Therapy in Amputation Wounds of the Diabetic Foot
The purpose of this study is to compare the effectiveness of Vacuum Assisted Closure® (V.A.C.®) Therapy to moist wound therapy of amputation wounds of the diabetic foot.
- Trial name
- NCT00224796
- Testing
- V.A.C. ® System
- Volunteers
- 146 people
- Sponsor
- KCI USA, Inc
Breast Carcinoma, Prostate Carcinoma
Humidified Forest Oils for Immune System Recovery in Stage I-III Breast or Prostate Cancer
This clinical trial studies the feasibility of simulating forest therapy using humidified wood or fragrant oils, in improving immune cells, like natural killer cells, number and activity, and their downstream proteins, perforin…
- Trial name
- NCT05012813
- Testing
- Aromatherapy with Essential Oils
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- OHSU Knight Cancer Institute