Clinical trials: Skin Sensitization
Food Allergy, Eczema
Treatment of IgE Associated Eczema With Omega-3 Long Chain Polyunsaturated Fatty Acids in Infancy and the Development of Bronchial Asthma in Childhood
Although some causal factors in allergy development such as allergen exposure and environmental pollution have decreased during recent years, the incidence of the allergic diseases has increased in the Western world.
- Conditions
- Food Allergy, Eczema, Sensitisation
- Trial name
- Omega-Treat (NCT01473823)
- Testing
- Omega-3 LCPUFA
- Where
- Sweden
- Volunteers
- 160 people
- Sponsor
- Ostergotland County Council, Sweden
Skin Irritability, Skin Sensitization
Safety Dermatological Assessment of Topical Use Product Through Dressings Predictive Studies for Evaluation of Photoirritation and Dermal Photosensitivity
The purpose of this study is to prove the product tested does not cause photoirritation or photosensitization reactions when exposed to sun light.
- Trial name
- SAF DER ASSESS (NCT02441608)
- Testing
- KL029 Intimate Lubricant Gel
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Kley Hertz S/A
Healthy
Bovine Atelocollagen Skin Sensitization Test
Bovine atelocollagen skin testing of healthy adult volunteers to investigate the potential of allergy to atelocollagen medical device implants
- Trial name
- NCT05235087
- Testing
- Bovine atelocollagen intradermal injection
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- AscentX Medical, Inc.
Skin Care
Evaluation of Skin Irritancy and Sensitization of a Liquid Bandage
The investigational product constitutes a medical device that is freely accessible to consumers and, as such, must be safe under real or reasonably foreseeable conditions of use and its safety must be tested before being placed…
- Trial name
- NCT05876546
- Testing
- Liquid bandage, Saline Solution
- Where
- 2 sites in Brazil
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Eurofarma Laboratorios S.A.
Sensitization to Legumes
Prevalence of Sensitization to Legumes in a Region From Southern France (Légumineuses)
The Mediterranean diet is a model for health. Indeed, according to some epidemiological studies, it would participate in the prevention of various diseases such as cardiovascular diseases, diabetes type 2, cancer and obesity.
- Trial name
- Légumineuses (NCT03686891)
- Testing
- Skin prick tests with four native legumes
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Montpellier
Exercise Training, Breast Cancer
Moderate-Intensity Exercise and Pain Sensitization in Breast Cancer Survivors: A Case-Based Study
The aim of this study was to evaluate the feasibility, safety, and acceptability of a supervised, combined moderate-intensity aerobic and resistance training program designed to reduce pain sensitization in BCS with persistent…
- Conditions
- Exercise Training, Breast Cancer, Pain Management
- Trial name
- NCT07128030
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Universidad Rey Juan Carlos
Sensitivity, Contact
Dermatological Assessment of Primary Dermal Irritability Accumulated and Sensitization
This is a clinical study for health care product safety assessment. The research will be conducted with 92 subjects, aged 18 to 59 years.
- Trial name
- NCT04248556
- Testing
- Health care product
- Where
- Brazil
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Herbarium Laboratorio Botanico Ltda
Atopic Dermatitis, House Dust Mite Allergy
Skin Responses and T Cell Immunology After House Dust Mite Exposure in Sensitized Atopic Dermatitis Patients
The present study investigates the reaction of the skin upon exposure to house dust mite (HDM) in patients with atopic dermatitis who have antibodies against HDM in the blood.
- Trial name
- CODES (NCT05019209)
- Testing
- House Dust Mite Allergen, Allergen-free air
- Where
- 2 sites in Germany
- Volunteers
- 23 people
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Skin Irritation
Repeat Insult Patch Test of Skin Irritation/Sensitization for Cetaphil Dermacontrol Oil Control Moisturizer SPF 30
Determine if Cetaphil DermaControl Oil Control Moisturizer SPF 30 proves to be a contact sensitizer or irritant in certain individuals
- Trial name
- NCT01887808
- Testing
- Cetaphil DermaControl Oil Control Moisturizer SPF 30
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Asthma, Dermatitis, Atopic
Impact in Off-spring of Mothers After Perinatal Daily Intake of a Probiotic
A probiotic (Lactobacillus rhamnosus GG) supplement to pregnant women the last four weeks of pregnancy and three months after birth is expected to give a 40% reduction in risk of atopic sensitisation and allergic disease at two…
- Conditions
- Asthma, Dermatitis, Atopic, Rhinitis, Allergic, Perennial
- Trial name
- NCT00159523
- Testing
- Probiotic
- Where
- Norway
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Skin Lesion, Skin Lesions
Assessment of EF192A Potential Sensitization and Accumulated and Primary Irritability in Controlled/Maximized Conditions
The investigational product constitutes a medical device that is freely accessible to consumers and, as such, must be safe under real or reasonably foreseeable conditions of use and its safety must be tested before being placed…
- Conditions
- Skin Lesion, Skin Lesions, Skin Care
- Trial name
- Spray A (NCT06731062)
- Testing
- EF192A, Saline solution
- Where
- Brazil
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Eurofarma Laboratorios S.A.
Atopic Dermatitis
Prevention of Development of Transcutaneous Sensitization in Children With Atopic Dermatitis During Their First Year of Life
This experimental non-randomized clinical study is aimed at comparing the efficacy and safety assessment of the proposed topical therapy algorithms with the use of topical calcineurin inhibitors in reducing the severity of atopic…
- Trial name
- NCT04900948
- Testing
- Pimecrolimus cream 1%, cream 0.1% methylprednisolone aceponate
- Where
- Russia
- Volunteers
- 108 people
- Sponsor
- National Medical Research Center for Children's Health, Russian Federation
Sensitivity, Contact
Dermatological Assessment of Primary Dermal Irritability Accumulated and Sensitization of Hyaluronic Nasal Spray
Evaluate the potential of Primary Dermal Irritability, Accumulated Dermal Irritability and Dermal Sensitization, of health products through the application of Patch Test, proving the safety of the product for topical use.
- Trial name
- NCT05508243
- Testing
- Hyaluronic Nasal Spray
- Where
- Brazil
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Herbarium Laboratorio Botanico Ltda
Type I Allergy
Design of Optimally-diagnostic Skin Test Solutions for Diagnosis of Sensitisation to a Pollen and Dust Mite Mixture.
Multicenter Skin Prick Test
- Trial name
- NCT00665483
- Testing
- Skin Prick Test
- Where
- Germany
- Sponsor
- Allergopharma GmbH & Co. KG
Skin Sensitization
Human Repeat Insult Patch Test of Wound Dressings
The purpose of this study is to determine whether contact sensitization occurs to the skin of normal healthy human subjects, by repetitive application of IV Clear™, Tegaderm CHG™ and Silicone Vehicle Control dressings.
- Trial name
- NCT01368146
- Testing
- IV Clear™, Tegaderm CHG™, Silicone Vehicle Control Dressing
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Covalon Technologies Inc.
Skin Care
To Evaluate Skin Irritation and Skin Sensitisation of Developmental Cosmetic Facial Products
The aim of this study is to assess irritant or allergic response of 3 developmental cosmetic facial products following a conventional human repeated insult patch test methodology for 6 weeks.
- Trial name
- NCT04007159
- Testing
- Serum, Lotion, Cream
- Where
- Brazil
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Hypersensitivity, Food
Prospective Study About Sensitization Pattern to Insects as Food Source in Patients With House Dust Mite Allergy
Patients allergic to seafood and/or sensitized to Tropomyosin of Skin Prick tests SPT or crustacean origin will may be also be sensitized to edible insects.
- Trial name
- InFood (NCT04239131)
- Testing
- Skin prick test
- Where
- Switzerland
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Skin Irritation, Skin Sensitization
HRIPT Study to Evaluate the Irritation and Allergenic Potential of Medical-grade Norway Spruce (Picea Abies) Resin Salve (Abilar)
The goal of this clinical trial is to assess whether a medical-grade Norway spruce resin-based topical product (Abilar) causes skin irritation or allergic sensitization in healthy adult volunteers.
- Trial name
- HRIPT-REPRIP2M (NCT06810856)
- Testing
- Abilar® Resin Salve
- Where
- United Kingdom
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Repolar Pharmaceuticals Oy
Rhinitis, Allergic, Asthma
Animal Allergy in Korean Veterinary Researcher
The investigators will evaluate sensitization to animal allergens and allergic symptom during contacting animal allergens in Korean veterinary researchers who attend their annual conference.
- Conditions
- Rhinitis, Allergic, Asthma, Dermatitis, Atopic, Urticaria
- Trial name
- NCT02866864
- Testing
- Animal allergy +, Animal allergy -
- Where
- South Korea
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Gachon University Gil Medical Center
Lipedema
The Relationship Between Central Sensitization, Pain, and Psychosocial Factors in Individuals With Lipedema
This cross-sectional study will include women aged 18-75 with clinically diagnosed lipedema and healthy controls. Sociodemographic and clinical data will be collected, and participants will complete the Central Sensitization…
- Trial name
- NCT07240285
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital