Clinical trials: Skin Sores
Mycobacterium Ulcerans Disease, Buruli Ulcer
Timing of Surgical Intervention in Buruli Ulcer Patients Treated With Antibiotics
SUMMARY Rationale: Buruli ulcer, caused by Mycobacterium ulcerans, is an ulcerative disease endemic in West Africa. It often leads to functional limitations.
- Trial name
- Burulitime (NCT01432925)
- Testing
- surgical intervention on Buruli ulcer
- Where
- 2 sites in Benin
- Volunteers
- 119 people
- Sponsor
- University Medical Center Groningen
Pressure Injury, Sleep
Comparing Pressure Injury Occurrence in Patients Using Two Different Mattresses
The purpose of this project is to compare a newly developed automatic reversing dynamic air mattress, with a regular care mattress, which is in daily use at the hospital.
- Conditions
- Pressure Injury, Sleep, Pain, Satisfaction, Patient
- Trial name
- NCT05207891
- Testing
- Intervention mattress
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Sunnaas Rehabilitation Hospital
Diabetic Foot, Diabetic Foot Ulcer
Evaluating a Lifestyle Intervention to Prevent Recurrence of Diabetic Foot Ulcers
People with diabetes often experience foot ulcers, which can harm their ability to move, lower their quality of life, and increase the chances of losing a limb.
- Conditions
- Diabetic Foot, Diabetic Foot Ulcer, Foot Ulcer, Diabetic, Foot Wound
- Trial name
- NCT06487780
- Testing
- Lifestyle-focused Occupational Therapy Intervention, Education
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Southern California
Diabetic Foot Ulcer, Diabetic Foot
Adapting Lifestyle Offloading for DFUs
The goal of this pilot clinical trial is to develop and test a tailored occupational therapist-led lifestyle-focused intervention to aid patients in improving diabetic foot ulcer care.
- Trial name
- NCT06278935
- Testing
- Lifestyle-based intervention by an occupational therapist
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Southern California
Diabetic Foot Ulcer, Diabetic Foot
Treatment of Chronic Diabetic Foot Ulcers by Minimally Invasive Surgery
Despite the development of the control of DM and the great interest for the complications of the disease, even today the diabetic foot represents a challenge for the orthopaedic surgeon.
- Conditions
- Diabetic Foot Ulcer, Diabetic Foot, Diabetic Foot Infection, Diabetic Foot Ulcer Neuropathic
- Trial name
- DiabeticMIS1 (NCT03010215)
- Testing
- Distal Metatarsal Minimally invasive Osteotomy (DMMO)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Padova
Diabetic Foot Ulcer, Venous Leg Ulcer
DETEC® pH Point of Care Wound Diagnostic Test
The purpose of this study is to determine the relationship between wound alkalinity and the non-healing status of chronic ulcer wounds.
- Conditions
- Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer, Wound, Non-Healed
- Trial name
- NCT04614038
- Testing
- DETEC® pH
- Where
- 2 sites in United States
- Volunteers
- 450 people
- Sponsor
- Progenitec Inc.
Buruli Ulcer, Mycobacterium Ulcerans
BURULICO Drug Trial Study Protocol: RCT SR8/SR4+CR4, GHANA
The standard for treatment Buruli ulcer disease (BUD) used to be surgery but the WHO now advises streptomycin (S, 15 mg/kg daily, intramuscularly) and rifampicin (R,10 mg/kg daily) along with surgery.
- Trial name
- BURULICO (NCT00321178)
- Testing
- SR4 - switch to CR4
- Where
- 2 sites in Ghana
- Volunteers
- 151 people
- Sponsor
- University Medical Center Groningen
Chronic Ulcer of Leg or Foot, Diabetic Foot Ulcer
MAtrix Therapy for Hard-to-heal ChrOnic Wounds
CACIPLIQ20® is currently a class III CE marked medical device available in various European and non-European countries, and currently primarily used in managing hard-to-heal wounds.
- Conditions
- Chronic Ulcer of Leg or Foot, Diabetic Foot Ulcer, Arterial Ulcer, Venous Ulcer of Leg
- Trial name
- MATHCOW (NCT05170984)
- Testing
- CACIPLIQ20®
- Where
- France
- Volunteers
- 191 people
- Sponsor
- Organ, Tissue, Regeneration, Repair and Replacement
Pressure Ulcers, Bedsores, Decubitus Ulcer
Measurement of Cytokines (IL-1α) After Shear- Force Application at the Skin
Background: A pressure ulcer is localized tissue injury to the superficial layer of the skin and/ or the underlying tissue. Pressure ulcers are most likely to develop in skin areas exposed to pressure, shear and friction.
- Trial name
- NCT02020655
- Testing
- Shear- force model
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Pressure Ulcer, Pressure Injury
Usability Validation of Patient Monitoring Device for Pressure Injury Prevention and Fall Detection
This study describes a procedure to collect a subject's position, movement, physiological data and usability information using Masimo's investigational device.
- Conditions
- Pressure Ulcer, Pressure Injury, Falls Injury
- Trial name
- NCT03121144
- Testing
- Masimo Centroid System
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Masimo Corporation
Venous Leg Ulcer
Efficacy and Safety of a New Compression System URGO BD001 in the Treatment of VLU (FREEDOM)
The aim of this study is to evaluate the therapeutic efficacy and the safety of the new compression system URGO BD001 in the management of venous or mixed predominantly venous leg ulcers.
- Trial name
- FREEDOM (NCT04613687)
- Testing
- Compression bandage
- Volunteers
- 52 people
- Sponsor
- Laboratoires URGO
Diabetic Foot Ulcers
A Clinical Study of the Safety and Efficacy of MEBO Wound Ointment in Subjects With Diabetic Foot Ulcers
The objective of this study is to evaluate the safety and efficacy of MEBO in the treatment of subjects with diabetic foot ulcers (DFUs).
- Trial name
- NCT01070433
- Testing
- MEBO Wound Ointment (MEBO), Standard of Care
- Where
- 9 sites in United States
- Volunteers
- 75 people
- Sponsor
- Skingenix, Inc.
Diabetic Foot
Post-healing Follow-up Study in People With Remission of a Diabetic Foot Ulcer
To evaluate the benefit of multidisciplinary specific follow-up of patients with a healed diabetic foot ulcer at the rate of two annual consultation on wound recurrence.
- Trial name
- Pied-REM (NCT04892771)
- Where
- France
- Volunteers
- 129 people
- Sponsor
- Centre Hospitalier Sud Francilien
Diabetic Foot Ulcer, Venous Ulcer
Enhanced Ultrasound Treatment of Chronic Wounds With Monitoring of Healing and Quality of Life Outcomes
The purpose of this study is to evaluate the effect of low frequency, low intensity ultrasound treatment on wound healing and health-related quality of life with a randomized clinical trial of patients with venous ulcers or…
- Trial name
- NCT03041844
- Testing
- Low Frequency, Low Intensity Ultrasound
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Drexel University
Leg Ulcers
Biatain Ag vs Biatain in the Treament of Leg Ulcers
the objective of this investigation is to demonstrate the effect of the foam dressing Biatain Ag, compared to Biatain foam dressing( a product which is similar but does not contain a silver complex, in the healing of leg ulcers…
- Trial name
- NCT00807664
- Testing
- Biatain Ag, Biatain
- Volunteers
- 182 people
- Sponsor
- Coloplast A/S
Pyoderma Gangrenosum
A Study Assessing the Efficacy and Safety of Adalimumab in Active Ulcer(s) of Pyoderma Gangrenosum in Participants in Japan
This study is designed to investigate the efficacy, safety and pharmacokinetics of adalimumab in subjects in Japan with active ulcer(s) due to Pyoderma Gangrenosum (PG).
- Trial name
- NCT03311464
- Testing
- adalimumab
- Where
- 20 sites in Japan
- Volunteers
- 22 people
- Sponsor
- AbbVie
Diabetic Foot
Amputation Associated Factors and Prediction Model in Diabetic Foot Patients
Diabetic foot can lead to adverse consequences such as amputation and death, which seriously endangering the physical and mental health and quality of life for patients.
- Trial name
- NCT05186519
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Qianfoshan Hospital
Pressure Injuries, Pressure Ulcer Prevention
Gamified Learning for Pressure Injury Prevention
The goal of this Randomized Controlled Trial is to define the effect of gamified teaching methods for pressure injury prevention in intensive care nurses.
- Trial name
- NCT07028892
- Testing
- A gamified mobile learning, Booklet training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif Ersoy University
Pressure Ulcers Stage III, Pressure Ulcer, Stage IV
Effectiveness of Negative-Pressure Wound Therapy
This study aims to compare the effects of Negative-Pressure Wound Therapy and wet-to-dry dressing on Stages 3 and 4 pressure injuries, and to investigate the consistency of Three-Dimensional Wound Measurement Device findings with…
- Trial name
- NCT04311229
- Testing
- Negative-Pressure Wound Therapy group, contol group
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Diabetic Foot Ulcer
Assessment of the Efficacy and Tolerance of Sub-cutaneous Re-injection of Autologous Adipose-derived REGEnerative Cells in the Local Treatment of Neuropathic Diabetic Foot ulcERs
Diabetic foot ulcer (DFU) is a major complication and the leading cause of hospitalization among people with diabetes mellitus. It occurs in 15% of all patients with diabetes and precedes 84% of all lower leg amputations.
- Trial name
- REGENDER (NCT02866565)
- Testing
- adipose-derived regenerative cells (ADRCs)
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Assistance Publique Hopitaux De Marseille