Clinical trials: Skin Tear
Sjogren's Syndrome, Dry Eye
Differences in Corneal Structure and Function in Patients With Sjogrens vs. Non-Sjogrens Dry Eye
In this study the investigators plan to enroll three groups of patients: non-Sjogren's dry eye, Sjogren's dry eye and controls. The study has the following primary goals: 1.
- Conditions
- Sjogren's Syndrome, Dry Eye, Neurotrophic Keratitis
- Trial name
- IIR (NCT06364657)
- Testing
- Eye Exam
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Osteoarthritis Shoulder, Fracture
Multi Centre Study on TESS V2 Shoulder System
This study is a Post Market Clinical Follow-up study to fulfill the post market surveillance requirements. The data collected from this study will serve the purpose of confirming safety and performance of the TESS Shoulder System.
- Conditions
- Osteoarthritis Shoulder, Fracture, Rheumatoid Arthritis, Avascular Necrosis
- Trial name
- NCT03431857
- Testing
- TESS V2
- Where
- 2 sites in Belgium, France
- Volunteers
- 106 people
- Sponsor
- Zimmer Biomet
Vaginal Delivery, Suture, Complication
Mostafa Maged Four-stitch Technique in Closure the Episiotomy During Vaginal Delivery
Most primigravida is confronted with episiotomy during childbirth to prevent the perineal and vaginal lacerations which could be performed at birth.
- Conditions
- Vaginal Delivery, Suture, Complication, Tear; Cervix, Hematoma
- Trial name
- NCT05247073
- Testing
- patients of controlled group with routine closure of episiotomy, The Mostafa Maged four-stitch technique fore closure of the episiotomy
- Volunteers
- 50 people
- Sponsor
- Fayoum University
Skin Lacerations
Prospective Evaluation of Topical Anesthesia in Children
This study is designed to assess efficacy and comfort of LET solution vs. EMLA cream and topical infiltration of lidocaine.
- Trial name
- LET (NCT04378283)
- Testing
- LET gel (lidocaine 4%, epinephrine 0.1%, and tetracaine 0.5%), EMLA plus infiltration as anesthetic for wound repair.
- Where
- Germany
- Volunteers
- 99 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Osteo Arthritis Shoulders, Osteonecrosis
Exactech Shoulder Post Market Clinical Follow-up Study
The objective of this study is to collect and evaluate long-term clinical and radiographic outcomes data in order to better understand the safety and performance of the shoulder arthroplasty over time.
- Conditions
- Osteo Arthritis Shoulders, Osteonecrosis, Rotator Cuff Tears, Rotator Cuff Tear Arthropathy
- Trial name
- NCT05603728
- Where
- 40 sites in United States, Canada and 4 more
- Volunteers
- 20,000 people
- Sponsor
- Exactech
Breast Cancer
Clinical Trial to Evaluate the Safety and Efficacy of Breast Implant
The aim of this study is to evaluate the safety and efficacy of Cohesive Silicone Gel-Filled Breast Implant (CoSBI) produced by HansBiomed co.,Ltd. in breast reconstruction or augmentation
- Trial name
- NCT01711710
- Testing
- Cohesive Gel Breast Implant
- Where
- 2 sites in South Korea
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Dermatoporosis
Prevalence and Comorbidities of Dermatoporosis: a French Prospective Observational Study in General Medicine Consultation
The term dermatoporosis (DP) was proposed by JH. Saurat in 2004 and detailed in 2007 to describe a chronic cutaneous insufficiency and fragility syndrome.
- Trial name
- NCT05699980
- Where
- 15 sites in France
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- University of Lorraine
Breast Cancer, Ovarian Cancer
Investigating the Diagnostic Potential of Tear Proteins in Cancer - A Pilot Study
This Pilot Study is to investigate the tear proteins in a multitude of cancer types and indulge in biomarker discovery to manufacture simple, accurate, and novel tear-based diagnostic tests.
- Conditions
- Breast Cancer, Ovarian Cancer, Pancreatic Cancer, Prostate Cancer
- Trial name
- NCT05223218
- Testing
- Schirmer strip, a Class I Medical Device typically used to test for dry eye.
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Namida Lab
Dry Eye Disease
Efficacy and Safety of 20% and 100% Autologous Serum Eye Drops in Patients With Severe Dry Eye Disease (AST)
A prospective, single-blinded, randomized, controlled crossover trial was conducted in patients with severe dry eye syndrome. Topical treatment with autologous serum eye drops (ASED) diluted at 20%, undiluted ASED and…
- Trial name
- AST (NCT07469865)
- Testing
- Preservative-free artificial tears, Autologous serum eyedrops 20%, Autologous serum eyedrops 100%
- Where
- Belgium
- Volunteers
- 46 people
- Sponsor
- University Hospital, Ghent
Shoulder Arthritis, Shoulder Osteoarthritis
S-11 SMR TT Hybrid Glenoid and Cementless Finned Short Stem
Post-market, prospective, non randomized, open label, multicentre, clinical study analysing outcomes of shoulder arthroplasty with SMR TT Hybrid Glenoid with or without SMR Cementless Finned Short Stem
- Conditions
- Shoulder Arthritis, Shoulder Osteoarthritis, Arthrosis, Osteoarthritis
- Trial name
- NCT05314387
- Testing
- SMR TT Hybrid Glenoid without Cementless Finned Short Stem, SMR TT Hybrid Glenoid with Cementless Finned Short Stem
- Volunteers
- 100 people
- Sponsor
- Limacorporate S.p.a
Nurse's Role, Wound
Nurses' Level of Knowledge on Skin Tears: A Cross-Sectional Study
Skin tears (ST) are one of the skin integrity problems encountered in healthcare settings with rates equal to or greater than pressure injuries.
- Conditions
- Nurse's Role, Wound, Knowledge, Attitudes, Practice
- Trial name
- NCT05297721
- Testing
- Knowledge
- Where
- Turkey (Türkiye)
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Hatice Yüceler Kaçmaz
Contusions, Incision
Dermal Wound Closure Using Silkam®
Assessment of performance of Silkam® suture material for skin closure. A prospective, single center, single arm, observational study in daily practice.
- Conditions
- Contusions, Incision, Laceration
- Trial name
- DERMASILK (NCT05225714)
- Where
- Spain
- Volunteers
- 161 people
- Sponsor
- Aesculap AG
Laceration of Skin
IN Ketamine vs IN Midazolam and Fentanyl for Laceration Repair
Often, repair of the cuts (laceration repair) proves to be traumatic for the children and the parents. Nasal spray (Intranasal/IN) approaches for procedural pain reduction, such as during dental work, have been demonstrated to…
- Trial name
- NCT03528512
- Testing
- Ketamine, Midazolam and fentanyl
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Corewell Health East
Laceration, Incision
Optilene® Suture Material for Dermal Sutures
In this non-interventional study, Optilene® suture will be evaluated for skin closure in adult patients.
- Trial name
- OPTIDERMAL (NCT05240248)
- Where
- Spain
- Volunteers
- 172 people
- Sponsor
- Aesculap AG
Laceration of Skin, Distress, Emotional
Anxiolysis for Laceration Repair in Children
This is a 3-arm adaptive clinical trial to the optimal light sedative for reducing distress during laceration repair in children.
- Trial name
- ALICE (NCT05383495)
- Testing
- Dexmedetomidine, Midazolam Nasal Spray, Nitrous oxide
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Episiotomy, Perineal Tear
A Study Comparing Topical Skin Adhesive or Sutures for Closure Due to Episiotomy or Perineal Tears Following Childbirth
This is a randomized controlled trial and multi-centered study with a 2-arm design. The treatment group will receive topical skin adhesive for skin closure of their wound and the control will receive sutures.
- Trial name
- NCT00196508
- Testing
- High Viscosity DERMABOND
- Where
- 5 sites in United States
- Volunteers
- 118 people
- Sponsor
- Ethicon, Inc.
Laceration
A Randomized Post-market Study to Evaluate Zip Device Compared to Sutures for Laceration Repair in Pediatrics and Adults
The Zip-009 clinical investigation will enroll 26 paediatric and adult subjects requiring laceration repair and fulfilling the eligibility criteria for the clinical investigation.
- Trial name
- NCT03199456
- Testing
- Zip surgical skin closure device, Standard of Care sutures
- Where
- 2 sites in Sweden
- Volunteers
- 26 people
- Sponsor
- ZipLine Medical Inc.
Perineal Laceration Involving Skin, Delivery; Trauma
Perineal Body Length and Perineal Lacerations
The aim of this study was to evaluate the relationship between perineal body length and perineal laceration risk in primigravid patients.
- Trial name
- NCT03880552
- Testing
- Primigravid women with singleton pregnancy at 35th week over
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Cuff Tear Arthropathy, Osteoarthritis With Cuff Deficiency
Long-term Clinical Effectiveness of the Delta Xtend Reverse Total Shoulder
This post-marketing study is designed to collect data relating to the use of the Delta Xtend™ Total Shoulder Replacement System in shoulder with rotator cuff deficiencies.
- Conditions
- Cuff Tear Arthropathy, Osteoarthritis With Cuff Deficiency, Rheumatoid Arthritis, Post Traumatic Injury to Shoulder
- Trial name
- NCT00737087
- Testing
- Delta Xtend Reverse Total Shoulder
- Where
- 5 sites in Belgium, France and 1 more
- Volunteers
- 144 people
- Sponsor
- DePuy International
Conjunctival Diseases, Atopic Dermatitis
Cytokine Profile of Conjunctivitis, Performed Through Tears Analysis Among Patients Treated With Dupilumab
This study aims to assess the cytokine profile of tears in patients suffering from conjunctivitis versus patients without ocular involvement, when treated with Dupilumab
- Conditions
- Conjunctival Diseases, Atopic Dermatitis, Side Effect
- Trial name
- CYCLADDE (NCT04066998)
- Testing
- Tears sampling, Lashes sampling
- Volunteers
- 15 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon