Clinical trials: Skin Testing
Lupus Nephritis, Lupus Erythematosus, Systemic
Establishing Clinical Utility of a New Diagnostic Test for Rheumatology Patients
This study will collect high-quality randomized controlled data from a nationally representative sample of practicing rheumatologists to determine how they currently manage patients with SLE (systemic lupus erythematosus) and how…
- Trial name
- NCT04266860
- Testing
- Experimental - Test Results and Education
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Healthy Volunteers
Skin Safety Study to Evaluate the Irritation Potential in Healthy Volunteers
This is a single center, randomized, controlled, within-subject comparison, multiple dose study to determine the irritation potential of M518101 on normal skin under occlusive patch condition.
- Trial name
- NCT02227069
- Testing
- M518101, M518101 Vehicle, sodium lauryl sulfate
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maruho North America Inc.
Breast Cancer
Biomarker Testing and Treatment Patterns Among Patients With PIK3CA Mutation in Advanced Breast Cancer
This was a retrospective observational study of patients with advanced breast cancer (BC). This non-interventional study was conducted using discrete structured data and medical record abstraction, if needed, from patients…
- Trial name
- NCT05982886
- Where
- United States
- Volunteers
- 1,093 people
- Sponsor
- Novartis Pharmaceuticals
Breast Neoplasms
Comparison of Diagnostic Performance of Digital Breast Tomosynthesis and Ultrasound in Women With Dense Breasts
Diagnostic performance of digital breast tomosynthesis (DBT) would be not inferior to the that of breast ultrasound in women with dense breast.
- Trial name
- NCT01910103
- Where
- South Korea
- Volunteers
- 825 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Immune Thrombocytopenia
RP% Measurement by FCM as a Diagnostic Test for ITP
Immature platelets-also termed reticulated platelets (RP)-are platelets newly released into the circulation, and have been associated with a variety of pathological bleeding events including primary immune thrombocytopenia (ITP).
- Trial name
- NCT02967328
- Testing
- RP% Measurement by FCM as a Diagnostic Test for ITP
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Shandong University
Lupus Erythematosus, Systemic
Relationship Between Data Obtained With the LuGENE® Multiparameter Transcriptomics Blood Test and Clinical and Standard Laboratory Features of Patients With SLE (ReLATE)
This is an open label study to determine the association of the data obtained with LuGENE®, a transcriptomic-based LDT, with standard evaluation of patients diagnosed with SLE, including clinical involvement, SLEDAI score…
- Trial name
- ReLATE (NCT05845593)
- Testing
- Decision Support Test
- Where
- 11 sites in United States
- Volunteers
- 200 people
- Sponsor
- Ampel BioSolutions, LLC
Breast Cancer, Ovarian Cancer
Genetic Testing for Breast, Ovarian, Pancreatic, and Prostate Cancers
This study is evaluating the effect of two pre-test education methods on participants interested in genetic testing for hereditary cancer risk.
- Conditions
- Breast Cancer, Ovarian Cancer, Pancreatic Cancer, Metastatic Prostate Cancer
- Trial name
- GeneBOPP (NCT04330716)
- Testing
- Standard Genetic Counseling, Educational Video
- Where
- 6 sites in United States
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
TNBC - Triple-Negative Breast Cancer, Minimal Residual Disease
CtDNA Based MRD Testing for NAC Monitoring in TNBC
A prospective, multicenter, observational study to evaluate the correlation of Molecular Residual Disease (MRD) detection using circulating tumor DNA guided test to pathological complete response (pCR) after neoadjuvant…
- Trial name
- B-STRONGER-I (NCT06230185)
- Where
- 14 sites in United States
- Volunteers
- 422 people
- Sponsor
- Personalis Inc.
Atopic Dermatitis, Food Allergies
Frequency of Food Allergy Confirm by Oral Food Challenge Among Foods Avoidance in Atopic Dermatitis Children
Atopic dermatitis can be caused by several factors, including food allergy. Currently, the diagnosis of food allergy often performing skin tests and measuring specific IgE foods that many studies have shown that about 53% of…
- Trial name
- NCT06947252
- Testing
- Oral food challenge test
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Mahidol University
Netherton Syndrome
A Study to Test Whether Spesolimab Helps People With a Skin Disease Called Netherton Syndrome
This study is open to people with a skin disease called Netherton syndrome (NS). People can join the study if they are 12 years or older.
- Trial name
- NCT05856526
- Testing
- Spesolimab - solution for infusion, Spesolimab - solution for injection
- Where
- 28 sites in United States, Australia and 12 more
- Volunteers
- 43 people
- Sponsor
- Boehringer Ingelheim
Tuberculosis
Conversion Rate of (TST) Tuberculin Skin Test and Quantiferon-TB Gold In Tube Assay in Health Care Workers
The purpose of this study is to access conversion rate of TST (Tuberculin skin test) and Quantiferon-TB Gold In tube assay in health care workers.
- Trial name
- NCT01376843
- Where
- South Korea
- Volunteers
- 53 people
- Sponsor
- Yonsei University
Systemic Sclerosis, Pulmonary Arterial Hypertension
Early, Simple and Reliable Detection of Pulmonary Arterial Hypertension (PAH) in Systemic Sclerosis (SSc)
A two-stage prospective observational cohort study in scleroderma patients to evaluate screening tests and the incidence of pulmonary arterial hypertension and pulmonary hypertension
- Conditions
- Systemic Sclerosis, Pulmonary Arterial Hypertension, Pulmonary Hypertension
- Trial name
- DETECT (NCT00706082)
- Where
- 83 sites in United States, Austria and 18 more
- Volunteers
- 490 people
- Sponsor
- Actelion
Preeclampsia, Pregnancy Complications
The Correlation Between Immunological Reaction of the Seminal Fluid in the Mother's Blood and Pregnancy Complications
It is known that if there isn't an efficient exposure to the paternal antigens before conception, there is an increased risk for the pre-eclampsia (PE) cascade and other pregnancy complications to take place.
- Conditions
- Preeclampsia, Pregnancy Complications, Insemination; Complication, Immune Tolerance
- Trial name
- NCT04314518
- Where
- 2 sites in Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Metastatic Breast Cancer, Hormon Receptor Positive Breast Cancer
Organ Culture for Endocrine Resistant Next Line: A Treatment Selection Study in Metastatic Breast Cancer
This study evaluates whether testing fresh tumor samples outside the body can help guide treatment selection for patients with hormone receptor-positive, HER2-negative metastatic breast cancer that has progressed during endocrine…
- Trial name
- OCEAN (NCT07895160)
- Testing
- cResponse Ex Vivo Organ Culture (EVOC) Drug Sensitivity Assay
- Where
- Israel
- Volunteers
- 39 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Hypersensitivity
Open-Label Study to Evaluate the Immunogenicity of Bovine Collagen in ArteFill® by Skin Testing
The purpose of this study is to assess the clinical utility of the ArteFill® pre-treatment Skin Test in predicting and preventing hypersensitivity reactions to treatment with ArteFill® implant
- Trial name
- NCT00778089
- Testing
- ArteFill® Skin Test
- Where
- United States
- Volunteers
- 498 people, healthy volunteers welcome
- Sponsor
- Suneva Medical, Inc.
Pressure Ulcers
Simplified Acute Physiology Score 2 and Pressure Ulcer Prediction in ICU.
Critically ill patients admitted in intensive care units are at high risk of developing pressure ulcer (also known as pressure injury).
- Trial name
- IGS-2-MIR (NCT07732517)
- Testing
- Pressure ulcer
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Bordeaux
Heat Cramps, Heat Rash
Testing Interventions to Mitigate the Health Impact of Heatwaves on Primary School Children in Climate-vulnerable Districts of Bangladesh.
The goal of this clinical trial is to assess the impact of implementing a combination of heat education and school-based physical infrastructure interventions in reducing heat related illnesses and improving educational outcomes…
- Conditions
- Heat Cramps, Heat Rash, Heat Exhaustion, Heat Stress
- Trial name
- NCT07877935
- Testing
- Solar reflective paint, Bamboo ceiling with polyethylene foam, Heat education toolkit
- Where
- 2 sites in Bangladesh
- Volunteers
- 2,875 people, healthy volunteers welcome
- Sponsor
- BRAC University
Breast Neoplasms, Uterine Cervical Neoplasms
Nudging Preventive Screening Via Message Framing and Bundling
This study is a randomized controlled field experiment embedded in the medical institution Early Diagnosis Program in Chile. Participants with two exams pending (a cancer screening test and a chronic disease test for diabetes and…
- Conditions
- Breast Neoplasms, Uterine Cervical Neoplasms, Colorectal Neoplasms, Prostatic Neoplasms
- Trial name
- NCT07644910
- Testing
- Basic cancer screening message, Basic chronic disease test message, Basic combined message
- Volunteers
- 235,000 people
- Sponsor
- University of Chile
Invasive Breast Carcinoma, Stage I Breast Cancer AJCC v7
Molecular Testing and Imaging in Improving Response in Patients With Stage I-III Triple-Negative Breast Cancer Receiving Chemotherapy MDACC Breast Moonshot Initiative
This clinical trial assesses whether a newly designed algorithm which looks at the genomic signature of each patient's tumor to predict their sensitivity to standard of care treatment verses being placed on a personally designed…
- Conditions
- Invasive Breast Carcinoma, Stage I Breast Cancer AJCC v7, Stage IA Breast Cancer AJCC v7, Stage IB Breast Cancer AJCC v7
- Trial name
- NCT02276443
- Testing
- Chemotherapy, Immunotherapy, Laboratory Biomarker Analysis
- Where
- 5 sites in United States
- Volunteers
- 798 people
- Sponsor
- M.D. Anderson Cancer Center
Body Image, Psychological Distress
Testing a Body-functionality Intervention for Body Image in Individuals With Skin Conditions
'Expand Your Horizons', a self-help writing intervention that seeks to train individuals to focus on what their body can do (functionality) rather than what it looks like (appearance), has produced promising results in improving…
- Conditions
- Body Image, Psychological Distress, Dermatologic Disease, Quality of Life
- Trial name
- NCT04445974
- Testing
- Expand your horizons: More than my skin, Creative writing activities
- Where
- United Kingdom
- Volunteers
- 454 people
- Sponsor
- University of Sheffield
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