Clinical trials: Skin Tests
Breast Cancer
Accurate, Rapid and Inexpensive MRI Protocol for Breast Cancer Screening
The purpose of this study is to test an innovative MRI breast cancer screening method in women with mammographically dense breasts as well as other women with moderately increased cancer risk.
- Trial name
- NCT04877912
- Testing
- MRI Abbreviated Scan, Abbreviated MRI Scan
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Melanoma
Utility of Novel BRAF Test for Melanoma
This primary purpose of this study is to obtain blood samples from participants with both early and later stages of melanoma (Stage II/III and Stage IV).
- Trial name
- NCT01840527
- Where
- 3 sites in United States
- Volunteers
- 220 people
- Sponsor
- Massachusetts General Hospital
Breast Cancer, Colorectal Cancer
KanSurvive: Testing a Model for Improving Cancer Survivorship Care in Rural Practice
Approximately, 20 rural primary care practices to participate in a delayed intervention-controlled trial. Phase I: Formal and structured work flow evaluations to better identify specific gaps in processes of care while assessing…
- Conditions
- Breast Cancer, Colorectal Cancer, Lung Cancer, Prostate Cancer
- Trial name
- KANSURVIVE (NCT04763824)
- Testing
- KanSurvive ECHO and Practice Facilitation
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Eosinophilic Esophagitis, Connective Tissue Disorders
Testing Effectiveness of Losartan in Patients With EoE With or Without a CTD
The purpose of this research study is to test the safety of losartan potassium and see what effects (good and bad) it has on you and your eosinophilic esophagitis.
- Trial name
- NCT01808196
- Testing
- Losartan Potassium
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Skin Irritation
Cetaphil® Daily Facial Moisturizer With Sunscreen SPF 50+ - Human Repeat Insult Patch Test
This study examined the possible sensitization and irritation effects of a moisturizer with sunscreen SPF 50+.
- Trial name
- NCT01892657
- Testing
- Facial Moisturizer with SPF 50+
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Melanoma, Young Adult
Risk Information and Skin-cancer Education for Undergraduate Prevention
The purpose of this study will be to provide undergraduate students information about skin cancer risk and prevention. The study will last between 2-3 months.
- Trial name
- RISE-UP (NCT03979872)
- Testing
- MC1R Genetic Testing, Skin Cancer Education, UV Photo
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Utah
Healthy
A Study in Healthy Men to Test How BI 765080 is Taken up in the Body When Given as an Injection Under the Skin Compared With an Infusion Into the Vein
A study in healthy man to investigate the absolute bioavailability of 100mg BI 765080, once administered as subcutaneous (SC) injection and once administered as intravenous infusion.
- Trial name
- NCT05075772
- Testing
- BI 765080
- Where
- Belgium
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Metastatic Breast Adenocarcinoma, Metastatic HER2-Positive Breast Carcinoma
Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer
This randomized phase III trial studies how well paclitaxel, trastuzumab, and pertuzumab with or without atezolizumab works in treating patients with breast cancer that has spread to other parts of the body (metastatic).
- Conditions
- Metastatic Breast Adenocarcinoma, Metastatic HER2-Positive Breast Carcinoma, Recurrent Breast Adenocarcinoma, Recurrent HER2-Positive Breast Carcinoma
- Trial name
- NCT03199885
- Testing
- Atezolizumab, Biopsy, Bone Scan
- Where
- 673 sites in United States, Canada
- Volunteers
- 190 people
- Sponsor
- National Cancer Institute (NCI)
Healthy, Psoriasis
This Study Tests How Healthy Men Tolerate Different Doses of BI 730357 and How the Metabolism of Midazolam is Affected by BI 730357
Phase Ib evaluation of the safety, tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) properties of Multiple Rising Dose (MRD) administration of BI 730357 to healthy volunteers for up to 28 days.
- Trial name
- NCT03279978
- Testing
- BI 730357, Midazolam
- Where
- Germany
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Colostomy Stoma
Human Skin Test Model in Colostomists
The aim of the study is to investigate the correlation in peel force when peeling off a standard hydrocolloid adhesive strip and standard strata adhesive strip from peristomal skin compared to pre-stripped healthy abdominal skin…
- Trial name
- NCT01918085
- Testing
- Hydrocolloid strip, Strata strip
- Volunteers
- 22 people
- Sponsor
- Coloplast A/S
Advanced Solid Tumor
Pembrolizumab (Anti-PD-1) and AMG386 (Angiopoietin-2 (Ang-2) in Patients With Advanced Solid Tumor
This research study is studying an investigational combination of drugs as a possible treatment for advanced solid tumors: melanoma, ovarian, renal, or colorectal cancer. The drugs involved in this study are: Pembrolizumab AMG386
- Trial name
- NCT03239145
- Testing
- Pembrolizumab, Trebananib
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- Dana-Farber Cancer Institute
Erythema, Edema
Human Repeat Insult Patch Test to Evaluate Personal Lubricants
The purpose of this test is to evaluate the sensitizing potential of a personal lubricant, as a result of repeated occlusive patch.
- Trial name
- HRIPT (NCT02737631)
- Testing
- "Chameleon" Personal Lubricant
- Where
- United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Metastatic Melanoma, Stage IIIB Cutaneous Melanoma AJCC v7
Imiquimod and Pembrolizumab in Treating Patients With Stage IIIB-IV Melanoma
This pilot early phase I trial studies the side effects and how well imiquimod and pembrolizumab work in treating patients with stage IIIB-IV melanoma. Imiquimod may stimulate the immune system.
- Conditions
- Metastatic Melanoma, Stage IIIB Cutaneous Melanoma AJCC v7, Stage IIIC Cutaneous Melanoma AJCC v7, Stage IV Cutaneous Melanoma AJCC v6 and v7
- Trial name
- NCT03276832
- Testing
- Imiquimod, Biopsy, Pembrolizumab
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Mayo Clinic
Dermatitis, Atopic
A Study to Test the Long-term Safety of BI 655130 in Patients With Atopic Eczema Who Took Part in Study 1368-0032
To assess the long term safety and efficacy of treatment with BI 655130 in patients with AD who have completed and have responded to treatment in the parent study 1368-0032
- Trial name
- NCT04086121
- Testing
- Spesolimab
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 14 people
- Sponsor
- Boehringer Ingelheim
Skin Diseases
Evaluation of CL Detect™ Rapid Test to Detect Cutaneous Leishmaniasis
This study is a single-site trial assessing the specificity of CL Detect™ Rapid Test versus the gold standard for Leishmania diagnosis in the US which is microscopic identification of Leishmania amastigotes in a stained lesion…
- Trial name
- NCT01865032
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- U.S. Army Medical Research and Development Command
Hypersensitivity
Study to Determine Skin Irritation Potential of an Antifungal Cream Containing Trolamine After Repeated Skin Application (Cumulative Irritation Patch Test)
In this study researchers want to study the potential skin reaction after repeated application of an antifungal cream containing trolamine.
- Trial name
- NCT04531813
- Testing
- Butenafine HCl 1% (BAY1896425), Positive Control-Sodium lauryl sulfate (SLS), Negative Control
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bayer
Antimicrobial Effectiveness
Topical Antimicrobial Effectiveness Testing
The primary objective of this study is to measure the antimicrobial effectiveness of ChloraPrep one-Step.
- Trial name
- NCT01314703
- Testing
- ChloraPrep One-Step, 70% isopropyl alcohol
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- C. R. Bard
Breast Carcinoma, Colon Carcinoma
Clinical Outcomes for Offering Genetic Testing in a Tiered Approach
This clinical quality improvement study reviews and develops a clinical operations workflow to identify cancer patients who meet criteria for genetic counseling and testing.
- Conditions
- Breast Carcinoma, Colon Carcinoma, Malignant Solid Neoplasm, Ovarian Carcinoma
- Trial name
- NCT04902144
- Testing
- Electronic Health Record Review, Questionnaire Administration, Behavioral Intervention
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Fred Hutchinson Cancer Center
Psoriasis
This Study is Done in Patients With Plaque Psoriasis and Tests How Well They Tolerate BI 730357 and How Effective it is
The primary objective is based on Week 12 co-primary endpoints of PASI (Psoriasis Area and Severity Index) 75 and sPGA (Static Physician's Global Assessment) 0/1, and overall safety Secondary objectives of Part 1 are to evaluate…
- Trial name
- NCT03635099
- Testing
- BI 25 mg (fasted), BI 50 mg (fasted), BI 100 mg (fasted)
- Where
- 34 sites in United States, Canada and 1 more
- Volunteers
- 274 people
- Sponsor
- Boehringer Ingelheim
Allergic Contact Dermatitis
Bioequivalence of Ethylenediamine Dihydrochloride Study
The purpose of this study is to compare the allergen ethylenediamine dihydrochloride when prepared using methylcellulose versus preparation using polyvinylpyrrolidone.
- Trial name
- NCT01798589
- Testing
- Ethylenediamine dihydrochloride allergen patch
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Allerderm